Experiment set2IT051 for Sinorhizobium meliloti 1021

Compare to:

LB with Sodium perchlorate monohydrate 10 mM

200 most detrimental genes:

  gene name fitness t score description  
SMc00647 +10.2 40.9 ribosomal large subunit pseudouridine synthase compare
SMc04003 +9.9 35.5 50S ribosomal protein L36 compare
SMc02659 +9.7 22.7 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00565 +8.7 13.6 50S ribosomal protein L9 compare
SMc00566 +8.0 20.3 hypothetical protein compare
SMc00349 +7.9 52.2 GTP-binding protein LepA compare
SMc03069 +7.8 22.2 6-phosphogluconolactonase compare
SMc00427 +7.7 22.4 peptide chain release factor RF-3 protein compare
SMc01099 +7.6 34.2 tRNA pseudouridine synthase A compare
SMc00711 +7.2 34.3 cyclohexadienyl dehydrogenase compare
SMc02367 +6.5 44.8 sensor histidine kinase transmembrane protein compare
SMc02366 +6.4 49.9 transcriptional regulator compare
SMc03826 +6.3 22.1 argininosuccinate synthase compare
SMc02365 +6.3 17.4 protease precursor protein compare
SMc02137 +6.1 43.7 ornithine carbamoyltransferase compare
SMc03863 +6.0 3.8 50S ribosomal protein L19 compare
SMc02695 +6.0 40.3 GTP-dependent nucleic acid-binding protein EngD compare
SMc00131 +6.0 41.7 transcriptional regulator compare
SMc03855 +5.8 9.8 hypothetical protein compare
SMc02112 +5.8 28.8 hypothetical protein compare
SMc01206 +5.8 23.4 queuine tRNA-ribosyltransferase compare
SMc03900 +5.6 37.6 cyclic beta-1,2-glucan ABc transporter compare
SMc04382 +5.6 38.4 beta-(1,2)-glucan production associated transmembrane protein compare
SMc00320 +5.5 11.0 ribosome-binding factor A compare
SMc04454 +5.4 29.5 ABC transporter ATP-binding protein compare
SMc01275 +5.0 10.8 ribosomal large subunit pseudouridine synthase C protein compare
SMc00495 +5.0 13.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02558 +4.9 16.1 hypothetical protein compare
SMc01124 +4.8 11.4 PII uridylyl-transferase compare
SMc01215 +4.7 27.4 carbamoyl phosphate synthase large subunit compare
SMc02058 +4.6 11.1 YAJC protein compare
SMc04094 +4.6 14.7 hypothetical protein compare
SMc01569 +4.5 10.1 carbamoyl phosphate synthase small subunit compare
SMa2020 +4.4 11.2 Transcriptional regulator compare
SMc00458 +4.4 33.5 transcriptional regulator compare
SMc00150 +4.2 38.0 hypothetical protein compare
SMc01222 +4.2 9.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc01801 +4.1 4.5 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00419 +4.1 16.7 glutathione synthetase compare
SMc02757 +4.0 4.1 hypothetical protein compare
SMc02497 +3.9 9.2 hypothetical protein compare
SMc01907 +3.9 30.6 hypothetical protein compare
SMc01207 +3.8 8.6 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc00321 +3.8 17.1 tRNA pseudouridine synthase B compare
SMc00482 +3.7 16.9 hypothetical protein compare
SMc01223 +3.7 3.3 transcriptional regulator compare
SMc02520 +3.6 25.7 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) (from data) compare
SMc02055 +3.6 8.2 phytoene synthase compare
SM_b20613 +3.5 18.9 C4-dicarboxylate transport transcriptional regulator compare
SMc01858 +3.5 8.2 S-adenosyl-methyltransferase MraW compare
SMc00710 +3.5 6.8 histidinol-phosphate aminotransferase compare
SMc02138 +3.5 8.1 acetylornithine transaminase compare
SMc00070 +3.5 19.0 signal peptide protein compare
SMc02434 +3.4 6.8 hypothetical protein compare
SMc02640 +3.3 14.2 UDP-glucuronic acid epimerase compare
SMc00622 +3.3 18.6 ribonuclease D protein compare
SM_b20414 +3.2 3.5 hypothetical protein compare
SMc02503 +3.2 8.2 hypothetical protein compare
SMc02714 +3.2 6.9 hypothetical protein compare
SMc02095 +3.0 8.9 hypothetical protein compare
SMc00403 +3.0 18.5 NOL1/NOP2/SUN family signature protein compare
SMc04001 +3.0 4.2 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc04235 +3.0 15.7 tRNA-dihydrouridine synthase A compare
SMc00998 +3.0 18.1 signal peptide protein compare
SMc04385 +3.0 7.9 L-2-aminoadipate semialdehyde dehydrogenase (EC 1.2.1.31) (from data) compare
SMc01613 +3.0 10.7 ribose-5-phosphate isomerase B compare
SMc00129 +3.0 14.9 sensor histidine kinase compare
SMc02713 +2.9 7.8 RNA polymerase sigma-E factor (sigma-24) protein compare
SMc01768 +2.9 5.0 transcriptional regulator compare
SM_b20131 +2.8 1.6 oxidoreductase compare
SM_b20146 +2.8 6.5 pyridoxal phosphate biosynthetic protein compare
SMc03933 +2.8 21.8 sarcosine oxidase subunit B protein compare
SMc00169 +2.8 22.6 malic enzyme compare
SM_b21397 +2.8 1.7 hypothetical protein compare
SMc04000 +2.8 3.4 hypothetical protein compare
SMc01726 +2.8 11.8 acetylglutamate kinase compare
SMc02385 +2.8 9.6 hypothetical protein compare
SMc03159 +2.7 4.7 ABC transporter ATP-binding protein compare
SMc00522 +2.7 16.7 ATP-dependent RNA helicase compare
SMc02245 +2.7 11.6 dihydroorotate dehydrogenase 2 compare
SMc02166 +2.6 15.2 dihydroorotase compare
SMc00329 +2.6 7.9 iron response regulator protein compare
SMa2029 +2.6 2.2 amidohydrolase compare
SMc00877 +2.6 18.0 transcriptional regulator compare
SMc03931 +2.6 19.5 sarcosine oxidase subunit alpha compare
SMc01120 +2.5 6.5 hypothetical protein compare
SMc04383 +2.5 7.9 putative hydrolase, required for lysine catabolism (from data) compare
SMc00450 +2.5 7.9 protoheme IX farnesyltransferase compare
SMc00761 +2.5 17.5 oxidoreductase compare
SMa0674 +2.4 1.8 hypothetical protein compare
SMc02050 +2.4 7.8 trigger factor compare
SMc01698 +2.3 14.2 oxidoreductase compare
SMc03996 +2.3 6.7 thiamine-phosphate pyrophosphorylase compare
SMc03158 +2.2 2.7 ABC transporter permease compare
SMc02755 +2.2 9.5 S-adenosyl-L-homocysteine hydrolase compare
SMc01454 +2.2 17.3 hypothetical protein compare
SMc03932 +2.2 7.8 sarcosine oxidase subunit delta compare
SMc01439 +2.2 9.3 hypothetical protein compare
SM_b21443 +2.1 1.3 hypothetical protein compare
SMc00513 +2.1 9.6 amino acid-binding periplasmic protein compare
SMc03930 +2.1 3.4 sarcosine oxidase subunit gamma compare
SMc00325 +2.1 12.5 hypothetical protein compare
SMc00727 +2.1 10.8 3-hydroxybutyryl-CoA dehydrogenase compare
SMc03157 +2.1 11.2 outer membrane lipoprotein transmembrane compare
SMc02384 +2.1 11.9 glycosyltransferase transmembrane protein compare
SMc02056 +2.0 3.4 hypothetical protein compare
SMc00648 +2.0 4.8 hypothetical protein compare
SMc02504 +2.0 3.9 transcriptional regulator compare
SMc02246 +2.0 2.8 hypothetical protein compare
SMc00009 +2.0 5.3 cytochrome C oxidase subunit II protein compare
SMc01852 +2.0 10.4 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SMc02765 +2.0 12.5 tryptophan synthase subunit alpha compare
SMa1256 +1.9 1.6 hypothetical protein compare
SMc03111 +1.9 8.2 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMc01131 +1.9 4.8 hypothetical protein compare
SMc02981 +1.9 1.3 amino acid efflux transmembrane protein compare
SM_b21192 +1.8 11.2 fructose-1,6-bisphosphate aldolase compare
SMc02407 +1.8 8.6 hypothetical protein compare
SMc02766 +1.8 12.2 tryptophan synthase subunit beta compare
SM_b21265 +1.8 4.4 glycosyltransferase compare
SMc01139 +1.8 6.0 RNA polymerase factor sigma-54 compare
SMc03037 +1.8 1.0 flagellin A compare
SMc00010 +1.7 3.8 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc00904 +1.7 4.5 hypothetical protein compare
SM_b21181 +1.6 6.2 glutaryl-CoA dehydrogenase compare
SMc01440 +1.6 6.8 hydrolase serine protease transmembrane protein compare
SMc00061 +1.6 3.1 hypothetical protein compare
SMc00709 +1.6 4.4 hypothetical protein compare
SMc04002 +1.6 8.6 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00361 +1.6 3.8 hypothetical protein compare
SM_b21491 +1.6 9.4 hypothetical protein compare
SMa0222 +1.6 2.0 GntR family transcriptional regulator compare
SMc01193 +1.6 8.8 hypothetical protein compare
SMc01885 +1.6 8.4 aminopeptidase P protein compare
SMc01347 +1.5 6.5 hypothetical protein compare
SMc00075 +1.5 4.6 ribosomal-protein-alanine acetyltransferase compare
SM_b20751 +1.5 1.6 3-hydroxyisobutyrate dehydrogenase compare
SMc01471 +1.5 3.7 cytochrome C oxidase assembly factor transmembrane protein compare
SMc04384 +1.5 4.2 (R)-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
SMa5000 +1.5 1.5 hypothetical protein compare
SMc00247 +1.5 7.8 phosphatidylcholine synthase compare
SMc00787 +1.5 5.3 peptide ABC transporter permease compare
SM_b20684 +1.4 10.1 hypothetical protein compare
SM_b20819 +1.4 1.4 ferredoxin compare
SMa0870 +1.4 1.6 NodD1 nod-box dependent transcriptional activator compare
SMc01800 +1.4 2.1 cytochrome C oxidase assembly transmembrane protein compare
SM_b21170 +1.4 7.0 guanylate kinase compare
SMc02361 +1.4 1.4 cytochrome C-type biogenesis transmembrane protein compare
SMc00786 +1.4 10.6 periplasmic dipeptide-binding protein compare
SMc01412 +1.4 1.7 hypothetical protein compare
SMc04441 +1.4 1.3 hypothetical protein compare
SM_b21208 +1.4 2.2 TetR family transcriptional regulator compare
SMc01428 +1.4 2.2 cold shock transcription regulator protein compare
SMc02864 +1.4 1.2 molybdopterin biosynthesis protein MoeB compare
SMa0326 +1.4 2.9 short chain alcohol dehydrogenase-related dehydrogenase compare
SMa5036 +1.3 3.5 hypothetical protein compare
SMa0854 +1.3 0.9 3-ketoacyl-ACP reductase compare
SMa2034 +1.3 1.8 hypothetical protein compare
SMc01107 +1.3 6.7 hypothetical protein compare
SMc01441 +1.3 5.1 membrane bound protease compare
SM_b21256 +1.3 5.7 nucleotide sugar oxidase compare
SMc02449 +1.3 2.5 acetyltransferase compare
SMc02269 +1.3 4.2 capsular polysaccharide biosynthesis/export protein compare
SMc00017 +1.3 2.3 homoserine kinase compare
SMc04882 +1.3 3.7 transcriptional regulator compare
SMc02577 +1.2 6.1 ATP-dependent protease ATP-binding subunit HslU compare
SMc01108 +1.2 5.9 tRNA (guanine-N(7)-)-methyltransferase compare
SMc02565 +1.2 2.6 hypothetical protein compare
SM_b20145 +1.2 2.4 hypothetical protein compare
SMc01203 +1.2 2.7 hypothetical protein compare
SMc00790 +1.2 8.3 peptide ABC transporter ATP-binding protein compare
SMc01939 +1.2 1.7 urease subunit beta compare
SMc00618 +1.2 6.3 polyphosphate kinase compare
SMc00412 +1.2 5.4 orotidine 5'-phosphate decarboxylase compare
SM_b21431 +1.2 5.4 hypothetical protein compare
SMc02084 +1.2 1.0 biopolymer transport transmembrane protein compare
SMc02024 +1.2 1.6 hypothetical protein compare
SMc02309 +1.2 5.1 arsenate reductase compare
SMc00789 +1.2 4.8 peptide ABC transporter ATP-binding protein compare
SMa1921 +1.2 1.4 hypothetical protein compare
SMc00788 +1.2 4.2 peptide ABC transporter permease compare
SMc02165 +1.2 2.9 orotate phosphoribosyltransferase compare
SM_b21372 +1.2 8.0 LacI family transcriptional regulator compare
SMc00174 +1.2 4.3 hypothetical protein compare
SMc02057 +1.2 4.9 preprotein translocase subunit SecD/SecF compare
SMc03969 +1.2 5.7 hypothetical protein compare
SMc02052 +1.2 1.2 hypothetical protein compare
SMc00194 +1.2 4.7 hypothetical protein compare
SMc02983 +1.2 6.2 ornithine, DAP, or arginine decarboxylase compare
SMc01127 +1.2 3.9 hypothetical protein compare
SMa1630 +1.2 1.4 hypothetical protein compare
SMc02478 +1.2 5.3 hypothetical protein compare
SMc04043 +1.1 4.5 hypothetical protein compare
SMc01993 +1.1 1.6 dioxygenase ferredoxin protein compare
SMc00239 +1.1 1.2 hypothetical protein compare
SMc04341 +1.1 1.8 amino acid-binding periplasmic protein compare
SMc00880 +1.1 4.1 oxidoreductase compare
SM_b20611 +1.1 7.9 C4-dicarboxylate transporter DctA compare
SM_b20815 +1.1 1.5 outer membrane protein assembly protein compare
SMc01093 +1.1 1.7 esterase compare


Specific Phenotypes

For 11 genes in this experiment

For stress Sodium perchlorate monohydrate in Sinorhizobium meliloti 1021

For stress Sodium perchlorate monohydrate across organisms