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Experiment set2IT050 for
Methanococcus maripaludis JJ
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H2 McCas, 5g/L bicarb, 40 psi H2CO2
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS09190
-5.2
-3.2
tryptophan synthase subunit beta
compare
MMJJ
_RS09375
-4.1
-2.6
hypothetical protein
compare
MMJJ
_RS07950
-4.1
-4.8
4Fe-4S binding protein
compare
MMJJ
_RS04730
-3.9
-3.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS00370
-3.7
-3.4
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS01755
-3.5
-3.4
ferrous iron transport protein B
compare
MMJJ
_RS06840
-3.4
-4.6
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS04475
-3.4
-6.0
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS05535
-3.4
-15.9
hypothetical protein
compare
MMJJ
_RS00275
-3.4
-3.9
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS05650
-3.3
-3.9
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS03055
-3.3
-4.7
hypothetical protein
compare
MMJJ
_RS04685
-3.3
-11.2
carbamoyltransferase HypF
compare
MMJJ
_RS07350
-3.2
-5.2
4Fe-4S binding protein
compare
MMJJ
_RS08625
-3.2
-9.8
magnesium/cobalt transporter CorA
compare
MMJJ
_RS00355
-3.2
-4.3
ribonuclease P protein component 4
compare
MMJJ
_RS05620
-3.2
-5.2
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS05590
-3.1
-3.3
homoserine dehydrogenase
compare
MMJJ
_RS04485
-3.1
-10.9
riboflavin synthase
compare
MMJJ
_RS07455
-3.1
-8.1
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS00560
-3.1
-4.4
homoisocitrate dehydrogenase
compare
MMJJ
_RS06750
-3.1
-3.6
homoaconitase large subunit
compare
MMJJ
_RS07945
-3.0
-4.0
4Fe-4S binding protein
compare
MMJJ
_RS06600
-3.0
-4.4
DUF555 domain-containing protein
compare
MMJJ
_RS01600
-3.0
-4.4
radical SAM protein
compare
MMJJ
_RS06910
-3.0
-4.9
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS06490
-3.0
-4.0
methanogenesis marker 2 protein
compare
MMJJ
_RS06155
-3.0
-7.2
phosphatidylglycerophosphatase A
compare
MMJJ
_RS08660
-2.9
-4.7
acetylornithine transaminase
compare
MMJJ
_RS03620
-2.9
-6.5
DUF2097 domain-containing protein
compare
MMJJ
_RS08080
-2.9
-11.2
TIGR00300 family protein
compare
MMJJ
_RS03670
-2.8
-5.5
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS07725
-2.8
-8.4
DNA primase DnaG
compare
MMJJ
_RS06855
-2.8
-2.6
DUF2104 domain-containing protein
compare
MMJJ
_RS01350
-2.8
-7.2
sodium:proton antiporter
compare
MMJJ
_RS07470
-2.8
-2.7
50S ribosome-binding GTPase
compare
MMJJ
_RS03005
-2.8
-4.1
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS01935
-2.7
-6.1
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS04700
-2.7
-8.7
deoxyhypusine synthase
compare
MMJJ
_RS04595
-2.7
-6.5
hypothetical protein
compare
MMJJ
_RS07360
-2.7
-2.6
TIGR00269 family protein
compare
MMJJ
_RS06255
-2.7
-8.3
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS06860
-2.7
-4.0
hypothetical protein
compare
MMJJ
_RS06225
-2.7
-2.8
adenosylmethionine decarboxylase
compare
MMJJ
_RS03230
-2.7
-6.0
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS06270
-2.7
-9.4
dethiobiotin synthase
compare
MMJJ
_RS00645
-2.6
-14.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS08095
-2.6
-4.8
cobyric acid synthase CobQ
compare
MMJJ
_RS02045
-2.6
-4.7
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS04200
-2.6
-8.1
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS05380
-2.5
-2.2
hypothetical protein
compare
MMJJ
_RS06625
-2.5
-2.5
pyruvate synthase subunit PorB
compare
MMJJ
_RS06040
-2.5
-5.1
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS07000
-2.5
-2.7
TrkH family potassium uptake protein
compare
MMJJ
_RS05995
-2.5
-3.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04980
-2.5
-5.5
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS03580
-2.5
-3.9
TIGR00303 family protein
compare
MMJJ
_RS00270
-2.4
-3.9
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS04995
-2.4
-6.4
Tfx family DNA-binding protein
compare
MMJJ
_RS08010
-2.4
-7.3
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS06510
-2.4
-3.3
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS03225
-2.4
-3.8
4Fe-4S binding protein
compare
MMJJ
_RS09135
-2.4
-11.2
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS07980
-2.4
-12.7
biotin synthase BioB
compare
MMJJ
_RS05155
-2.4
-7.8
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS04145
-2.4
-10.0
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS01750
-2.4
-3.6
ferrous iron transport protein A
compare
MMJJ
_RS07720
-2.4
-2.9
UPF0058 family protein
compare
MMJJ
_RS08535
-2.4
-4.8
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS02200
-2.4
-10.0
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS01880
-2.3
-3.5
RlmE family RNA methyltransferase
compare
MMJJ
_RS06695
-2.3
-3.4
amidohydrolase
compare
MMJJ
_RS05260
-2.3
-6.3
ATP-grasp domain-containing protein
compare
MMJJ
_RS07705
-2.3
-3.5
GTP-binding protein EngB
compare
MMJJ
_RS03840
-2.3
-4.7
DHH family phosphoesterase
compare
MMJJ
_RS02090
-2.3
-6.7
tyramine--L-glutamate ligase
compare
MMJJ
_RS01200
-2.3
-3.3
PRC-barrel domain-containing protein
compare
MMJJ
_RS06715
-2.3
-12.0
lactaldehyde dehydrogenase
compare
MMJJ
_RS08840
-2.3
-4.6
calcium/sodium antiporter
compare
MMJJ
_RS08055
-2.2
-8.1
methanogenesis marker 14 protein
compare
MMJJ
_RS02920
-2.2
-3.1
30S ribosomal protein S27ae
compare
MMJJ
_RS06260
-2.2
-7.3
6-carboxyhexanoate--CoA ligase
compare
MMJJ
_RS01870
-2.2
-2.0
methanogenesis marker 15 protein
compare
MMJJ
_RS03760
-2.2
-4.1
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS00475
-2.2
-3.4
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS00125
-2.2
-3.2
KEOPS complex subunit Cgi121
compare
MMJJ
_RS05655
-2.2
-6.5
HisA/HisF family protein
compare
MMJJ
_RS08850
-2.2
-2.4
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS03190
-2.2
-4.0
phosphopyruvate hydratase
compare
MMJJ
_RS04155
-2.2
-7.3
hypothetical protein
compare
MMJJ
_RS03865
-2.2
-3.4
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS04520
-2.1
-6.2
coenzyme F430 synthase
compare
MMJJ
_RS06875
-2.1
-2.1
hypothetical protein
compare
MMJJ
_RS06390
-2.1
-2.7
NADPH-dependent F420 reductase
compare
MMJJ
_RS00215
-2.1
-3.3
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS06175
-2.1
-3.1
DUF1743 domain-containing protein
compare
MMJJ
_RS03615
-2.1
-3.8
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS06725
-2.1
-13.0
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05375
-2.1
-14.3
radical SAM protein
compare
MMJJ
_RS07430
-2.1
-5.2
ribonuclease VapC
compare
MMJJ
_RS06265
-2.1
-12.9
8-amino-7-oxononanoate synthase
compare
MMJJ
_RS08575
-2.1
-5.9
hypothetical protein
compare
MMJJ
_RS03965
-2.1
-3.1
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS07190
-2.0
-4.5
RtcB family protein
compare
MMJJ
_RS08330
-2.0
-3.8
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS00205
-2.0
-5.9
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS03200
-2.0
-2.3
uroporphyrinogen-III synthase
compare
MMJJ
_RS05930
-2.0
-2.1
cell division protein SepF
compare
MMJJ
_RS03820
-2.0
-3.8
hydrogenase formation protein HypD
compare
MMJJ
_RS03540
-2.0
-5.9
TIGR00289 family protein
compare
MMJJ
_RS05575
-2.0
-4.6
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS08870
-2.0
-2.2
2-isopropylmalate synthase
compare
MMJJ
_RS06805
-2.0
-3.9
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS01690
-2.0
-3.7
methanogenesis marker 12 protein
compare
MMJJ
_RS03895
-2.0
-4.0
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS06185
-2.0
-4.9
cobalamin biosynthesis protein
compare
MMJJ
_RS03125
-1.9
-4.3
GMC oxidoreductase
compare
MMJJ
_RS04565
-1.9
-3.3
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS05070
-1.9
-2.3
DNA primase catalytic subunit PriS
compare
MMJJ
_RS04150
-1.9
-3.8
DUF5379 domain-containing protein
compare
MMJJ
_RS06220
-1.9
-5.7
polyamine aminopropyltransferase
compare
MMJJ
_RS07160
-1.9
-15.1
M20 family metallo-hydrolase
compare
MMJJ
_RS00425
-1.9
-4.0
hypothetical protein
compare
MMJJ
_RS06835
-1.9
-11.5
4Fe-4S binding protein
compare
MMJJ
_RS03115
-1.9
-6.1
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS02275
-1.9
-4.0
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03845
-1.9
-3.1
translation initiation factor IF-2
compare
MMJJ
_RS06930
-1.9
-3.4
type II methionyl aminopeptidase
compare
MMJJ
_RS01830
-1.9
-3.9
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS04800
-1.8
-7.0
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS06375
-1.8
-3.1
UbiX family flavin prenyltransferase
compare
MMJJ
_RS07275
-1.8
-2.4
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS03095
-1.8
-2.8
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS01875
-1.8
-5.2
global nitrogen regulator NrpR
compare
MMJJ
_RS07375
-1.8
-7.8
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMJJ
_RS03245
-1.8
-2.1
UMP kinase
compare
MMJJ
_RS04680
-1.8
-8.9
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMJJ
_RS07245
-1.8
-5.3
amidohydrolase family protein
compare
MMJJ
_RS05935
-1.8
-2.8
Era-like GTP-binding protein
compare
MMJJ
_RS08620
-1.8
-3.5
DUF373 family protein
compare
MMJJ
_RS03170
-1.8
-8.7
DUF5612 domain-containing protein
compare
MMJJ
_RS06915
-1.8
-10.5
helix-turn-helix domain-containing protein
compare
MMJJ
_RS03765
-1.8
-8.3
hypothetical protein
compare
MMJJ
_RS02035
-1.8
-8.4
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMJJ
_RS06250
-1.8
-2.8
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS00360
-1.8
-2.3
adenosylhomocysteinase
compare
MMJJ
_RS05295
-1.8
-8.9
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS05330
-1.8
-2.7
DNA polymerase II large subunit
compare
MMJJ
_RS05065
-1.8
-4.1
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS06010
-1.8
-6.6
hypothetical protein
compare
MMJJ
_RS01415
-1.7
-2.4
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS03650
-1.7
-5.3
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS04790
-1.7
-3.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS07785
-1.7
-2.7
fumarate reductase subunit A
compare
MMJJ
_RS03785
-1.7
-3.2
hypothetical protein
compare
MMJJ
_RS02855
-1.7
-8.5
DEAD/DEAH box helicase
compare
MMJJ
_RS04670
-1.7
-3.4
DUF2117 domain-containing protein
compare
MMJJ
_RS03150
-1.7
-5.6
2-phospho-L-lactate transferase
compare
MMJJ
_RS06905
-1.6
-2.8
hypothetical protein
compare
MMJJ
_RS03060
-1.6
-2.9
methanogenesis marker 7 protein
compare
MMJJ
_RS07875
-1.6
-2.7
FAD-dependent oxidoreductase
compare
MMJJ
_RS04650
-1.6
-4.7
nitrogenase iron protein
compare
MMJJ
_RS00600
-1.6
-3.1
hydroxymethylbilane synthase
compare
MMJJ
_RS08155
-1.6
-4.8
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS03110
-1.6
-3.8
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS01345
-1.6
-3.4
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS05950
-1.6
-3.5
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS04970
-1.6
-2.0
DUF655 domain-containing protein
compare
MMJJ
_RS06865
-1.6
-2.5
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS07715
-1.6
-3.3
UbiD family decarboxylase
compare
MMJJ
_RS00450
-1.6
-2.6
DUF126 domain-containing protein
compare
MMJJ
_RS02040
-1.6
-2.4
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS03295
-1.6
-10.3
PHP domain-containing protein
compare
MMJJ
_RS07155
-1.6
-7.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS09055
-1.6
-8.1
NFACT family protein
compare
MMJJ
_RS08250
-1.6
-5.9
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS00580
-1.6
-2.3
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS00570
-1.5
-1.4
ribonuclease P
compare
MMJJ
_RS08020
-1.5
-9.1
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS05490
-1.5
-2.7
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS08000
-1.5
-9.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS08340
-1.5
-5.0
archaeoflavoprotein AfpA
compare
MMJJ
_RS06050
-1.5
-8.6
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS05540
-1.5
-12.0
LysR family transcriptional regulator
compare
MMJJ
_RS03660
-1.5
-3.6
DUF447 family protein
compare
MMJJ
_RS08825
-1.5
-6.0
hypothetical protein
compare
MMJJ
_RS05225
-1.5
-1.1
Gar1/Naf1 family protein
compare
MMJJ
_RS04050
-1.5
-2.0
dihydroneopterin aldolase family protein
compare
MMJJ
_RS05610
-1.5
-3.8
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS01360
-1.5
-2.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS05810
-1.5
-4.9
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS06700
-1.4
-4.9
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS00210
-1.4
-1.6
DUF530 family protein
compare
MMJJ
_RS07345
-1.4
-6.1
homocysteine biosynthesis protein
compare
MMJJ
_RS04985
-1.4
-2.0
glutamyl-tRNA reductase
compare
MMJJ
_RS02190
-1.4
-9.8
molybdopterin biosynthesis protein
compare
MMJJ
_RS06785
-1.4
-5.3
RNA ligase partner protein
compare
MMJJ
_RS07370
-1.4
-3.3
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS08320
-1.4
-2.0
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS04675
-1.4
-5.3
thiamine pyrophosphate-binding protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in rich t1 experiments