Experiment set2IT045 for Shewanella loihica PV-4

Compare to:

LB with Sodium Chlorite 200 mM

200 most detrimental genes:

  gene name fitness t score description  
Shew_3729 +3.9 4.7 coproporphyrinogen III oxidase (RefSeq) compare
Shew_2642 +3.6 6.2 flavodoxin (RefSeq) compare
Shew_2000 +3.6 3.7 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_0755 +3.6 5.8 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_1058 +3.5 13.5 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_3660 +3.5 27.6 glutathione reductase (RefSeq) compare
Shew_1563 +3.3 15.5 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_3311 +3.3 14.6 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_2572 +3.1 8.1 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1224 +3.1 22.7 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1601 +2.9 3.3 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_0296 +2.9 1.8 heat shock protein Hsp20 (RefSeq) compare
Shew_3500 +2.8 5.1 putative endoribonuclease L-PSP (RefSeq) compare
Shew_R0076 +2.6 2.3 tRNA-Asn (RefSeq) compare
Shew_1819 +2.6 4.5 GntR family transcriptional regulator (RefSeq) compare
Shew_1992 +2.4 5.5 hypothetical protein (RefSeq) compare
Shew_1341 +2.3 4.4 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_0709 +2.2 14.5 catalase/peroxidase HPI (RefSeq) compare
Shew_1278 +2.2 1.2 hypothetical protein (RefSeq) compare
Shew_1092 +2.0 6.8 amino acid carrier protein (RefSeq) compare
Shew_3682 +2.0 10.9 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1810 +1.9 5.9 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_1985 +1.9 3.6 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shew_1298 guaA +1.9 6.9 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_3262 +1.9 1.4 hypothetical protein (RefSeq) compare
Shew_1445 +1.9 1.1 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), small permease component (from data) compare
Shew_0728 +1.8 11.9 dihydroorotase (RefSeq) compare
Shew_3681 +1.8 9.1 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2906 +1.8 1.7 hypothetical protein (RefSeq) compare
Shew_3710 tdh +1.8 7.1 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1202 +1.8 9.9 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_3786 +1.8 1.5 hypothetical protein (RefSeq) compare
Shew_0086 +1.7 13.2 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_0570 +1.7 1.2 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_1432 +1.7 1.9 ferredoxin-type protein NapF (RefSeq) compare
Shew_3379 +1.7 3.2 hypothetical protein (RefSeq) compare
Shew_3498 rpoZ +1.7 4.8 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_1657 sucC +1.7 1.6 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_3709 +1.7 12.7 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_0462 +1.7 1.2 hypothetical protein (RefSeq) compare
Shew_2584 +1.6 7.7 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_3560 +1.6 6.7 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_3442 +1.6 2.9 hypothetical protein (RefSeq) compare
Shew_3295 +1.6 10.0 AFG1 family ATPase (RefSeq) compare
Shew_1987 +1.6 3.4 Cbb3-type cytochrome oxidase component (RefSeq) compare
Shew_0450 +1.6 7.9 1-acyl-sn-glycerol-3-phosphate acyltransferase (RefSeq) compare
Shew_3684 +1.5 9.9 binding-protein-dependent transport systems inner membrane component (RefSeq) compare
Shew_0932 +1.5 1.5 radical SAM domain-containing protein (RefSeq) compare
Shew_1531 grxA +1.5 2.6 glutaredoxin 1 (RefSeq) compare
Shew_1731 +1.5 0.8 histidine triad (HIT) protein (RefSeq) compare
Shew_3443 +1.5 1.3 hypothetical protein (RefSeq) compare
Shew_2957 +1.5 3.4 hypothetical protein (RefSeq) compare
Shew_1673 fabG +1.5 1.2 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_1223 +1.4 1.1 hypothetical protein (RefSeq) compare
Shew_2895 +1.4 4.2 2-dehydropantoate 2-reductase (RefSeq) compare
Shew_3683 +1.4 4.0 extracellular solute-binding protein (RefSeq) compare
Shew_1990 +1.4 2.1 heavy metal translocating P-type ATPase (RefSeq) compare
Shew_2061 +1.4 1.5 radical SAM domain-containing protein (RefSeq) compare
Shew_3687 +1.4 10.3 molybdopterin-guanine dinucleotide biosynthesis protein B (RefSeq) compare
Shew_1287 +1.4 2.7 hypothetical protein (RefSeq) compare
Shew_2175 nhaB +1.4 5.1 sodium/proton antiporter (RefSeq) compare
Shew_3487 pyrE +1.4 2.9 orotate phosphoribosyltransferase (RefSeq) compare
Shew_1477 +1.3 3.5 anti-ECFsigma factor, ChrR (RefSeq) compare
Shew_3305 +1.3 3.5 CaCA family Na(+)/Ca(+) antiporter (RefSeq) compare
Shew_0343 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_0373 +1.3 3.0 hypothetical protein (RefSeq) compare
Shew_2643 +1.3 1.3 pseudouridylate synthase (RefSeq) compare
Shew_1865 +1.3 2.9 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_0261 +1.3 0.7 hypothetical protein (RefSeq) compare
Shew_1470 +1.3 3.8 sulfatase (RefSeq) compare
Shew_0860 +1.3 1.8 hypothetical protein (RefSeq) compare
Shew_2434 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_3685 +1.3 6.4 ABC transporter-related protein (RefSeq) compare
Shew_0390 +1.3 1.1 MSHA biogenesis protein MshM (RefSeq) compare
Shew_2327 +1.3 0.6 hypothetical protein (RefSeq) compare
Shew_3759 +1.2 7.1 imidazolonepropionase (RefSeq) compare
Shew_1716 +1.2 1.6 3-beta hydroxysteroid dehydrogenase/isomerase (RefSeq) compare
Shew_0055 +1.2 8.3 hypothetical protein (RefSeq) compare
Shew_1455 +1.2 0.8 dual specificity protein phosphatase (RefSeq) compare
Shew_1713 +1.2 1.7 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_1574 +1.2 3.9 ATP-binding Mrp/Nbp35 family protein (RefSeq) compare
Shew_2664 +1.2 5.0 transcriptional regulator, putative (RefSeq) compare
Shew_2349 +1.2 2.2 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_1230 +1.2 2.7 phosphoribosylaminoimidazole carboxylase, catalytic subunit (RefSeq) compare
Shew_0056 +1.2 8.2 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_1173 +1.2 1.9 hypothetical protein (RefSeq) compare
Shew_2140 +1.2 1.5 hypothetical protein (RefSeq) compare
Shew_2228 +1.2 4.8 inosine kinase (RefSeq) compare
Shew_0939 +1.2 5.8 leucyl aminopeptidase (RefSeq) compare
Shew_2406 +1.1 1.5 AraC family transcriptional regulator (RefSeq) compare
Shew_2668 +1.1 4.3 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_0396 +1.1 1.4 methylation site containing protein (RefSeq) compare
Shew_0059 +1.1 8.0 molybdopterin oxidoreductase (RefSeq) compare
Shew_2667 +1.1 7.0 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_0220 +1.1 3.6 phosphoglycolate phosphatase (RefSeq) compare
Shew_2386 +1.1 3.5 hypothetical protein (RefSeq) compare
Shew_2458 +1.1 0.7 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_0383 +1.1 4.7 malate dehydrogenase (RefSeq) compare
Shew_2049 +1.1 2.6 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_3267 +1.1 3.4 sodium/hydrogen exchanger (RefSeq) compare
Shew_1859 +1.1 0.8 carbonate dehydratase (RefSeq) compare
Shew_0060 +1.1 6.9 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_1714 +1.1 1.4 alpha/beta hydrolase fold (RefSeq) compare
Shew_3686 +1.1 4.5 molybdopterin-guanine dinucleotide biosynthesis protein A (RefSeq) compare
Shew_0414 +1.1 4.0 ABC-2 type transporter (RefSeq) compare
Shew_1140 +1.0 2.0 ferrochelatase (RefSeq) compare
Shew_2654 queF +1.0 2.0 7-cyano-7-deazaguanine reductase (RefSeq) compare
Shew_0412 +1.0 2.6 secretion protein HlyD family protein (RefSeq) compare
Shew_1575 +1.0 3.6 uridine kinase (RefSeq) compare
Shew_2537 +1.0 1.9 AraC family transcriptional regulator (RefSeq) compare
Shew_3064 gcvT +1.0 4.3 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_0284 +1.0 4.6 hypothetical protein (RefSeq) compare
Shew_2544 +1.0 1.5 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) compare
Shew_2199 +1.0 2.2 histidinol-phosphate aminotransferase (RefSeq) compare
Shew_0413 +1.0 3.3 ABC-2 type transporter (RefSeq) compare
Shew_0058 +1.0 4.8 twin-arginine translocation pathway signal (RefSeq) compare
Shew_3135 +1.0 3.3 L-lactate permease (RefSeq) compare
Shew_1295 +1.0 2.4 hypothetical protein (RefSeq) compare
Shew_2907 +1.0 1.6 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_0127 +1.0 2.3 LexA repressor (RefSeq) compare
Shew_3063 +1.0 1.1 glycine cleavage system protein H (RefSeq) compare
Shew_0054 +1.0 3.7 hypothetical protein (RefSeq) compare
Shew_2892 +1.0 2.3 major facilitator transporter (RefSeq) compare
Shew_0411 +1.0 2.9 outer membrane efflux protein (RefSeq) compare
Shew_2414 +1.0 3.3 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_1475 +1.0 3.7 hypothetical protein (RefSeq) compare
Shew_3561 +1.0 4.6 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_1898 +0.9 1.4 ApbE family lipoprotein (RefSeq) compare
Shew_1867 +0.9 1.7 hypothetical protein (RefSeq) compare
Shew_0588 +0.9 1.7 hypothetical protein (RefSeq) compare
Shew_2666 +0.9 5.2 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_3427 +0.9 3.3 patatin (RefSeq) compare
Shew_1669 +0.9 3.2 butyryl-CoA dehydrogenase (RefSeq) compare
Shew_0885 djlA +0.9 0.8 DNA-J like membrane chaperone protein (RefSeq) compare
Shew_0061 +0.9 5.0 formate dehydrogenase, gamma subunit (RefSeq) compare
Shew_1427 +0.9 1.3 3'(2'),5'-bisphosphate nucleotidase (RefSeq) compare
Shew_1820 prpB +0.9 1.7 2-methylisocitrate lyase (RefSeq) compare
Shew_0695 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_0620 +0.9 1.0 ion transport 2 domain-containing protein (RefSeq) compare
Shew_2665 +0.9 6.5 beta-ketoacyl synthase (RefSeq) compare
Shew_2410 +0.9 0.5 beta-ketoacyl synthase (RefSeq) compare
Shew_1357 +0.9 3.6 flagellin domain-containing protein (RefSeq) compare
Shew_0537 +0.8 0.8 hypothetical protein (RefSeq) compare
Shew_0854 +0.8 2.0 hypothetical protein (RefSeq) compare
Shew_0057 +0.8 1.4 cytoplasmic chaperone TorD family protein (RefSeq) compare
Shew_1122 +0.8 3.3 hypothetical protein (RefSeq) compare
Shew_3062 +0.8 4.1 glycine dehydrogenase (RefSeq) compare
Shew_1615 +0.8 2.2 ABC transporter-related protein (RefSeq) compare
Shew_1606 +0.8 0.5 hypothetical protein (RefSeq) compare
Shew_2992 +0.8 1.6 amidohydrolase (RefSeq) compare
Shew_1159 +0.8 1.6 thioesterase superfamily protein (RefSeq) compare
Shew_2687 +0.8 2.0 hypothetical protein (RefSeq) compare
Shew_3080 +0.8 2.2 thiol:disulfide interchange protein, putative (RefSeq) compare
Shew_0322 +0.8 3.7 diaminopimelate decarboxylase (RefSeq) compare
Shew_0834 +0.8 0.6 hypothetical protein (RefSeq) compare
Shew_0103 +0.8 2.1 sodium/glutamate symporter (RefSeq) compare
Shew_1602 +0.8 1.9 malonyl CoA-acyl carrier protein transacylase (RefSeq) compare
Shew_0421 +0.8 1.0 phage shock protein C, PspC (RefSeq) compare
Shew_2481 +0.8 2.1 porin (RefSeq) compare
Shew_2554 +0.8 0.6 outer membrane protein W (RefSeq) compare
Shew_3483 dut +0.8 0.4 deoxyuridine 5'-triphosphate nucleotidohydrolase (RefSeq) compare
Shew_1974 +0.8 2.1 hypothetical protein (RefSeq) compare
Shew_1797 +0.8 0.8 paraquat-inducible protein A (RefSeq) compare
Shew_2656 +0.8 3.6 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_3266 dipZ +0.8 1.1 thiol:disulfide interchange protein precursor (RefSeq) compare
Shew_1213 +0.8 0.8 RpoD family RNA polymerase sigma factor (RefSeq) compare
Shew_1300 +0.8 1.8 lytic transglycosylase, catalytic (RefSeq) compare
Shew_2153 +0.8 0.6 LysR family transcriptional regulator (RefSeq) compare
Shew_0078 +0.8 4.2 ribokinase-like domain-containing protein (RefSeq) compare
Shew_1163 +0.7 0.7 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_2961 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_2423 +0.7 1.4 hypothetical protein (RefSeq) compare
Shew_1085 +0.7 0.9 response regulator receiver protein (RefSeq) compare
Shew_3594 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_3499 +0.7 1.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_2910 +0.7 0.6 hypothetical protein (RefSeq) compare
Shew_1082 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_0422 +0.7 2.4 hypothetical protein (RefSeq) compare
Shew_0434 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_0802 +0.7 2.0 chromate transporter (RefSeq) compare
Shew_1684 +0.7 1.4 lysine exporter protein LysE/YggA (RefSeq) compare
Shew_2735 +0.7 3.2 patatin (RefSeq) compare
Shew_0053 +0.7 5.8 formate dehydrogenase, subunit FdhD (RefSeq) compare
Shew_0295 +0.7 2.1 hypothetical protein (RefSeq) compare
Shew_3364 +0.7 1.2 acetyl-CoA carboxylase, biotin carboxyl carrier protein (RefSeq) compare
Shew_2188 +0.7 1.8 long-chain-fatty-acid--CoA ligase (RefSeq) compare
Shew_2795 +0.7 2.6 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_1514 upp +0.7 1.5 uracil phosphoribosyltransferase (RefSeq) compare
Shew_1186 +0.7 1.1 transcriptional regulator NrdR (RefSeq) compare
Shew_2157 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_2956 +0.7 2.0 ECF subfamily RNA polymerase sigma-24 factor (RefSeq) compare
Shew_3349 +0.7 2.1 ATP-dependent protease La (RefSeq) compare
Shew_1126 +0.7 1.6 glutaminase (RefSeq) compare
Shew_1855 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_3319 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_1769 +0.7 0.7 NapD family protein (RefSeq) compare
Shew_3601 +0.7 1.7 O-succinylbenzoate synthase (RefSeq) compare
Shew_3653 +0.7 0.6 hypothetical protein (RefSeq) compare
Shew_2148 +0.7 1.1 hypothetical protein (RefSeq) compare
Shew_0548 +0.7 2.2 yqiA-like hydrolase, affects the cell envelope (from data) compare


Specific Phenotypes

For 9 genes in this experiment

For stress Sodium Chlorite in Shewanella loihica PV-4

For stress Sodium Chlorite across organisms