Experiment set2IT045 for Methanococcus maripaludis S2

Compare to:

Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE

200 most important genes:

  gene name fitness t score description  
MMP_RS01985 -9.4 -7.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06685 -8.8 -12.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06355 -8.7 -4.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06680 -8.6 -16.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06715 -8.5 -19.9 cache domain-containing protein compare
MMP_RS06975 -8.0 -3.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06720 -8.0 -9.3 response regulator transcription factor compare
MMP_RS08105 -7.9 -9.4 6-carboxyhexanoate--CoA ligase compare
MMP_RS06700 -7.9 -15.5 hypothetical protein compare
MMP_RS06345 -7.7 -11.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06350 -7.6 -8.5 HesA/MoeB/ThiF family protein compare
MMP_RS06895 -7.6 -3.7 selenocysteine-specific translation elongation factor compare
MMP_RS03015 -7.5 -12.5 GTP 3' 8-cyclase MoaA compare
MMP_RS06625 -7.5 -4.2 DNA primase compare
MMP_RS05515 -7.4 -8.4 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01175 -7.0 -6.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08100 -6.6 -9.0 8-amino-7-oxononanoate synthase compare
MMP_RS04500 -6.4 -20.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06705 -6.3 -8.6 formate/nitrite transporter family protein compare
MMP_RS07605 -6.3 -6.4 diadenylate cyclase compare
MMP_RS01980 -6.2 -19.4 trimeric intracellular cation channel family protein compare
MMP_RS06400 -6.2 -3.0 4Fe-4S binding protein compare
MMP_RS07845 -6.1 -4.5 LL-diaminopimelate aminotransferase compare
MMP_RS06370 -5.9 -8.7 biotin synthase BioB compare
MMP_RS07380 -5.8 -4.8 transcription elongation factor Spt5 compare
MMP_RS08095 -5.5 -8.7 dethiobiotin synthase compare
MMP_RS00300 -5.4 -1.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08300 -5.4 -2.6 metal-sulfur cluster assembly factor compare
MMP_RS08460 -5.4 -4.8 proteasome-activating nucleotidase compare
MMP_RS07005 -5.3 -1.5 4Fe-4S binding protein compare
MMP_RS04585 -5.2 -11.6 AIR synthase related protein compare
MMP_RS04775 -5.2 -5.8 adenosylhomocysteinase compare
MMP_RS08715 -5.1 -3.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04685 -5.1 -6.0 DUF126 domain-containing protein compare
MMP_RS00110 -5.0 -5.8 hypothetical protein compare
MMP_RS07645 -4.9 -7.4 aldehyde dehydrogenase family protein compare
MMP_RS02195 -4.9 -6.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS08820 -4.9 -9.2 hypothetical protein compare
MMP_RS01020 -4.9 -1.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS08645 -4.9 -10.7 UPF0179 family protein compare
MMP_RS00895 -4.9 -5.9 hypothetical protein compare
MMP_RS03960 -4.9 -1.9 hypothetical protein compare
MMP_RS01005 -4.8 -1.9 riboflavin synthase compare
MMP_RS04780 -4.8 -4.6 ribonuclease P compare
MMP_RS03315 -4.8 -2.2 ferrous iron transport protein A compare
MMP_RS08790 -4.7 -4.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS06295 -4.6 -10.2 methanogenesis marker 14 protein compare
MMP_RS03600 -4.5 -4.3 triose-phosphate isomerase compare
MMP_RS03025 -4.5 -10.0 molybdenum cofactor guanylyltransferase compare
MMP_RS00685 -4.4 -6.5 2-phospho-L-lactate guanylyltransferase compare
MMP_RS02345 -4.4 -6.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07635 -4.4 -9.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03035 -4.3 -7.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06475 -4.3 -6.5 FAD-dependent oxidoreductase compare
MMP_RS01500 -4.2 -4.6 CBS domain-containing protein compare
MMP_RS06630 -4.2 -2.3 UPF0058 family protein compare
MMP_RS06270 -4.2 -9.2 TIGR00300 family protein compare
MMP_RS07445 -4.2 -4.8 helix-turn-helix domain-containing protein compare
MMP_RS03580 -4.2 -4.4 signal recognition particle-docking protein FtsY compare
MMP_RS06730 -4.1 -3.7 phosphopantothenate/pantothenate synthetase compare
MMP_RS01755 -4.1 -2.8 DUF2097 domain-containing protein compare
MMP_RS00515 -4.1 -1.6 DUF655 domain-containing protein compare
MMP_RS02900 -4.1 -1.1 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06285 -4.1 -3.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01225 -4.0 -7.3 DUF5379 domain-containing protein compare
MMP_RS04890 -3.9 -1.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06925 -3.9 -4.4 ribonuclease VapC4 compare
MMP_RS08720 -3.9 -2.9 4Fe-4S binding protein compare
MMP_RS06230 -3.8 -5.1 helix-turn-helix domain-containing protein compare
MMP_RS04710 -3.8 -3.4 hypothetical protein compare
MMP_RS01220 -3.7 -11.7 hypothetical protein compare
MMP_RS02280 -3.7 -1.8 DUF211 domain-containing protein compare
MMP_RS00295 -3.7 -5.0 gamma carbonic anhydrase family protein compare
MMP_RS02340 -3.7 -3.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS06340 -3.6 -9.7 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02165 -3.6 -10.8 tRNA-dihydrouridine synthase compare
MMP_RS07765 -3.6 -10.8 sodium:alanine symporter family protein compare
MMP_RS03435 -3.6 -3.9 ketol-acid reductoisomerase compare
MMP_RS03475 -3.6 -1.4 hypothetical protein compare
MMP_RS03445 -3.5 -2.2 methanogenesis marker 17 protein compare
MMP_RS08435 -3.5 -3.6 Era-like GTP-binding protein compare
MMP_RS07195 -3.5 -13.8 M20 family metallo-hydrolase compare
MMP_RS00305 -3.4 -3.5 phosphoribosyl-ATP diphosphatase compare
MMP_RS06930 -3.4 -15.3 MBL fold metallo-hydrolase compare
MMP_RS01385 -3.4 -1.3 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS08650 -3.4 -5.1 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS02240 -3.4 -5.4 methanogenesis marker 7 protein compare
MMP_RS05510 -3.3 -10.0 Rrf2 family transcriptional regulator compare
MMP_RS00695 -3.3 -1.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS03640 -3.3 -5.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07630 -3.2 -3.0 ATP-binding cassette domain-containing protein compare
MMP_RS06120 -3.2 -2.6 UPF0147 family protein compare
MMP_RS08635 -3.2 -3.8 UbiA family prenyltransferase compare
MMP_RS00040 -3.2 -5.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01325 -3.2 -4.5 dihydroneopterin aldolase family protein compare
MMP_RS01800 -3.2 -5.4 TIGR00303 family protein compare
MMP_RS09020 -3.2 -2.2 hypothetical protein compare
MMP_RS02010 -3.1 -10.0 PHP domain-containing protein compare
MMP_RS07600 -3.1 -5.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08745 -3.1 -9.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07775 -3.1 -9.4 alanine dehydrogenase compare
MMP_RS03400 -3.0 -3.7 archease compare
MMP_RS00130 -3.0 -2.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS06020 -3.0 -5.4 archaeoflavoprotein AfpA compare
MMP_RS05815 -2.9 -4.7 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS02875 -2.9 -14.3 chorismate pyruvate-lyase family protein compare
MMP_RS08210 -2.8 -3.7 phosphatidylglycerophosphatase A compare
MMP_RS07580 -2.8 -3.5 DUF356 domain-containing protein compare
MMP_RS08320 -2.7 -7.8 molybdopterin molybdotransferase MoeA compare
MMP_RS01725 -2.7 -5.0 class I SAM-dependent methyltransferase family protein compare
MMP_RS05920 -2.7 -1.4 50S ribosomal protein L37e compare
MMP_RS02145 -2.6 -8.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS05430 -2.6 -3.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS06885 -2.6 -5.6 50S ribosome-binding GTPase compare
MMP_RS07735 -2.6 -1.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06200 -2.6 -12.3 M24 family metallopeptidase compare
MMP_RS01700 -2.5 -1.9 dihydroxy-acid dehydratase compare
MMP_RS02135 -2.5 -5.3 DUF5612 domain-containing protein compare
MMP_RS01610 -2.5 -5.2 hypothetical protein compare
MMP_RS07525 -2.5 -8.0 4Fe-4S binding protein compare
MMP_RS01380 -2.5 -5.9 PHP domain-containing protein compare
MMP_RS00290 -2.4 -8.8 hypothetical protein compare
MMP_RS05845 -2.4 -2.5 tRNA-intron lyase compare
MMP_RS07200 -2.4 -8.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS07755 -2.4 -2.4 DUF555 domain-containing protein compare
MMP_RS02355 -2.3 -4.4 30S ribosomal protein S27ae compare
MMP_RS06315 -2.3 -1.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS05345 -2.2 -7.3 hypothetical protein compare
MMP_RS05060 -2.2 -12.6 AAA family ATPase compare
MMP_RS03095 -2.2 -9.2 diphthine synthase compare
MMP_RS08840 -2.2 -12.6 class I SAM-dependent methyltransferase compare
MMP_RS00985 -2.2 -8.5 CDC48 family AAA ATPase compare
MMP_RS05085 -2.2 -12.2 AAA family ATPase compare
MMP_RS07575 -2.2 -5.1 RNA ligase partner protein compare
MMP_RS05100 -2.2 -17.2 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05095 -2.2 -8.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS02170 -2.1 -5.9 CBS domain-containing protein compare
MMP_RS02190 -2.1 -2.4 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS00115 -2.1 -14.4 radical SAM protein compare
MMP_RS01840 -2.1 -10.6 TIGR00289 family protein compare
MMP_RS06215 -2.1 -4.4 30S ribosomal protein S6e compare
MMP_RS07730 -2.0 -3.4 pyruvate synthase subunit beta compare
MMP_RS05925 -2.0 -7.3 small nuclear ribonucleoprotein compare
MMP_RS07390 -2.0 -3.7 cell division protein FtsZ compare
MMP_RS03590 -2.0 -10.5 METTL5 family protein compare
MMP_RS05070 -2.0 -7.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS03155 -1.9 -6.7 precorrin-6A reductase compare
MMP_RS07790 -1.9 -9.3 segregation/condensation protein A compare
MMP_RS07425 -1.9 -8.9 GTP-binding protein compare
MMP_RS07420 -1.9 -4.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05075 -1.9 -14.3 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS01795 -1.9 -1.7 methanogenesis marker 6 protein compare
MMP_RS07710 -1.9 -8.6 cell division protein FtsZ compare
MMP_RS07685 -1.9 -11.1 TIGR01212 family radical SAM protein compare
MMP_RS07545 -1.9 -1.8 HTH domain-containing protein compare
MMP_RS08445 -1.9 -5.7 DUF2099 family protein compare
MMP_RS01265 -1.9 -2.5 hypothetical protein compare
MMP_RS01830 -1.9 -2.5 tRNA-Val compare
MMP_RS04605 -1.8 -4.6 cobalt ECF transporter T component CbiQ compare
MMP_RS05090 -1.8 -10.4 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05055 -1.8 -13.6 DUF166 domain-containing protein compare
MMP_RS05540 -1.8 -2.5 hypothetical protein compare
MMP_RS05250 -1.8 -1.9 NFYB/HAP3 family transcription factor subunit compare
MMP_RS00720 -1.8 -8.9 metal-dependent hydrolase compare
MMP_RS06105 -1.8 -8.7 hydrogenase maturation peptidase HycI compare
MMP_RS05080 -1.8 -9.7 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00050 -1.7 -8.4 AarF/UbiB family protein compare
MMP_RS05545 -1.7 -9.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS05555 -1.7 -2.1 DUF4040 domain-containing protein compare
MMP_RS00035 -1.7 -8.6 DUF2098 family protein compare
MMP_RS01545 -1.7 -1.7 CBS domain-containing protein compare
MMP_RS02885 -1.7 -12.1 molybdopterin biosynthesis protein compare
MMP_RS04720 -1.7 -3.0 DedA family protein compare
MMP_RS07750 -1.6 -4.4 DUF357 domain-containing protein compare
MMP_RS05550 -1.6 -1.1 cation:proton antiporter compare
MMP_RS06980 -1.6 -6.9 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS05440 -1.6 -9.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS05765 -1.6 -6.2 M42 family metallopeptidase compare
MMP_RS03305 -1.6 -9.6 winged helix-turn-helix domain-containing protein compare
MMP_RS06725 -1.5 -8.9 hypothetical protein compare
MMP_RS07385 -1.5 -2.0 protein translocase SEC61 complex subunit gamma compare
MMP_RS08570 -1.5 -9.9 coenzyme F420-0:L-glutamate ligase compare
MMP_RS00730 -1.5 -5.8 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01720 -1.5 -1.1 replication factor C large subunit compare
MMP_RS04955 -1.5 -2.2 DNA topoisomerase I compare
MMP_RS04090 -1.5 -3.6 hypothetical protein compare
MMP_RS00915 -1.5 -6.2 DUF116 domain-containing protein compare
MMP_RS05505 -1.4 -9.8 class IV adenylate cyclase compare
MMP_RS00320 -1.4 -2.7 class I SAM-dependent methyltransferase compare
MMP_RS05065 -1.4 -4.3 CooT family nickel-binding protein compare
MMP_RS08690 -1.4 -8.5 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS03555 -1.4 -8.8 transcriptional regulator compare
MMP_RS03250 -1.4 -3.0 MJ1244 family protein compare
MMP_RS00900 -1.4 -3.4 50S ribosomal protein L39e compare
MMP_RS06865 -1.4 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02800 -1.4 -5.3 nucleotidyltransferase domain-containing protein compare
MMP_RS00060 -1.4 -2.3 3-dehydroquinate synthase II compare
MMP_RS07555 -1.4 -1.0 monovalent cation/H+ antiporter subunit E compare
MMP_RS08330 -1.4 -6.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS01085 -1.3 -2.9 hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For nutrient t2 Sodium acetate in Methanococcus maripaludis S2

For nutrient t2 Sodium acetate across organisms