Experiment set2IT044 for Methanococcus maripaludis S2

Compare to:

Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Vitamin FREE

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01370 +4.2 31.3 acetate--CoA ligase family protein compare
MMP_RS03215 +2.9 18.7 MBL fold metallo-hydrolase compare
MMP_RS07115 +2.3 13.8 MBL fold metallo-hydrolase compare
MMP_RS01960 +1.9 1.4 hypothetical protein compare
MMP_RS04480 +1.5 12.5 lysine 2 3-aminomutase compare
MMP_RS05535 +1.3 4.7 hypothetical protein compare
MMP_RS07850 +1.2 5.1 prephenate dehydratase compare
MMP_RS00530 +1.1 5.6 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS06600 +1.1 2.6 class III signal peptide-containing protein compare
MMP_RS04485 +1.0 8.4 putative beta-lysine N-acetyltransferase compare
MMP_RS02960 +1.0 5.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS06575 +1.0 4.4 fluoride efflux transporter CrcB compare
MMP_RS08275 +0.9 6.1 hypothetical protein compare
MMP_RS03420 +0.7 2.6 acetolactate synthase small subunit compare
MMP_RS05975 +0.7 1.8 hypothetical protein compare
MMP_RS06335 +0.7 5.2 HAD family hydrolase compare
MMP_RS06570 +0.7 4.1 DUF190 domain-containing protein compare
MMP_RS02310 +0.7 2.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS08775 +0.7 2.9 methanogenesis marker 9 domain-containing protein compare
MMP_RS07820 +0.6 3.0 UPF0104 family protein compare
MMP_RS08360 +0.6 2.2 hypothetical protein compare
MMP_RS07725 +0.6 2.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS06485 +0.6 1.3 zinc ribbon domain-containing protein compare
MMP_RS03320 +0.6 2.1 metal-dependent transcriptional regulator compare
MMP_RS08350 +0.6 1.0 hypothetical protein compare
MMP_RS07435 +0.6 1.3 GMP synthase subunit A compare
MMP_RS08340 +0.6 2.4 4Fe-4S binding protein compare
MMP_RS01030 +0.6 4.0 MTAP family purine nucleoside phosphorylase compare
MMP_RS05700 +0.5 4.1 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS06545 +0.5 3.1 ferredoxin family protein compare
MMP_RS08345 +0.5 3.8 4Fe-4S binding protein compare
MMP_RS00665 +0.5 2.4 hypothetical protein compare
MMP_RS05365 +0.5 1.0 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS08315 +0.5 2.0 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS09025 +0.5 1.0 hypothetical protein compare
MMP_RS08485 +0.5 3.6 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS01940 +0.5 1.9 MoxR family ATPase compare
MMP_RS08400 +0.5 2.3 MJ0307 family thioredoxin compare
MMP_RS08455 +0.5 1.9 multiprotein bridging factor aMBF1 compare
MMP_RS06290 +0.5 3.5 DNA repair and recombination protein RadA compare
MMP_RS08215 +0.5 2.0 DUF483 domain-containing protein compare
MMP_RS07410 +0.5 3.0 4-demethylwyosine synthase TYW1 compare
MMP_RS01660 +0.5 2.0 hypothetical protein compare
MMP_RS06585 +0.5 1.3 DMT family protein compare
MMP_RS05720 +0.4 1.6 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS07350 +0.4 1.5 preprotein translocase subunit Sec61beta compare
MMP_RS03450 +0.4 1.3 glycine synthesis protein GlyXS (from data) compare
MMP_RS08555 +0.4 1.5 hypothetical protein compare
MMP_RS07560 +0.4 2.6 prefoldin subunit alpha compare
MMP_RS02605 +0.4 0.6 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS00345 +0.4 3.1 DUF2666 domain-containing protein compare
MMP_RS01435 +0.4 2.1 DMT family transporter compare
MMP_RS07095 +0.4 1.4 PspC domain-containing protein compare
MMP_RS05950 +0.4 2.7 nickel-dependent hydrogenase large subunit compare
MMP_RS00285 +0.4 2.0 TIGR04013 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS07330 +0.4 3.2 membrane protein compare
MMP_RS05675 +0.4 1.2 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS08335 +0.4 1.9 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS01785 +0.4 2.9 hypothetical protein compare
MMP_RS06610 +0.4 2.0 DUF2334 domain-containing protein compare
MMP_RS03395 +0.4 1.6 hypothetical protein compare
MMP_RS02235 +0.4 2.3 CBS domain-containing protein compare
MMP_RS05435 +0.4 2.5 5'/3'-nucleotidase SurE compare
MMP_RS01990 +0.4 1.6 hypothetical protein compare
MMP_RS02935 +0.4 1.7 A24 family peptidase compare
MMP_RS08280 +0.4 1.6 proteasome assembly chaperone family protein compare
MMP_RS03245 +0.3 1.8 DNA repair and recombination protein RadB compare
MMP_RS06540 +0.3 1.5 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS08995 +0.3 0.8 hypothetical protein compare
MMP_RS02370 +0.3 1.2 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS08205 +0.3 2.0 stage II sporulation protein M compare
MMP_RS01115 +0.3 2.6 molybdopterin molybdotransferase MoeA compare
MMP_RS00100 +0.3 2.7 tRNA pseudouridine(13) synthase TruD compare
MMP_RS06325 +0.3 0.8 hypothetical protein compare
MMP_RS01055 +0.3 2.0 hypothetical protein compare
MMP_RS00770 +0.3 2.0 hypothetical protein compare
MMP_RS08365 +0.3 1.3 energy conserving hydrogenase EhbF compare
MMP_RS03670 +0.3 1.3 DUF1890 domain-containing protein compare
MMP_RS00990 +0.3 2.2 hypothetical protein compare
MMP_RS06860 +0.3 0.9 4Fe-4S binding protein compare
MMP_RS01945 +0.3 2.0 DUF4350 domain-containing protein compare
MMP_RS00630 +0.3 2.0 ECF transporter S component compare
MMP_RS08240 +0.3 1.8 methanogenesis marker 16 metalloprotein compare
MMP_RS08700 +0.3 2.2 hypothetical protein compare
MMP_RS02675 +0.3 0.9 hypothetical protein compare
MMP_RS01260 +0.3 1.3 HDIG domain-containing protein compare
MMP_RS05780 +0.3 2.8 multidrug resistance efflux transporter family protein compare
MMP_RS00700 +0.3 2.2 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS00655 +0.3 1.5 hypothetical protein compare
MMP_RS03300 +0.3 0.3 TOBE domain-containing protein compare
MMP_RS06300 +0.3 2.1 ABC transporter substrate-binding protein compare
MMP_RS00675 +0.3 0.4 nitroreductase family protein compare
MMP_RS06550 +0.3 2.0 AMP-binding protein compare
MMP_RS06655 +0.3 2.0 glycoside hydrolase family 15 protein compare
MMP_RS01460 +0.3 1.1 hypothetical protein compare
MMP_RS07090 +0.3 1.7 tRNA (adenine-N1)-methyltransferase compare
MMP_RS06490 +0.3 1.6 hypothetical protein compare
MMP_RS01570 +0.3 0.7 hypothetical protein compare
MMP_RS05990 +0.3 1.1 DsrE family protein compare
MMP_RS01775 +0.3 1.1 TIGR00297 family protein compare
MMP_RS08430 +0.3 1.7 HAD family hydrolase compare
MMP_RS00185 +0.3 2.3 potassium channel protein compare
MMP_RS05900 +0.3 1.9 tetratricopeptide repeat protein compare
MMP_RS01650 +0.3 0.4 sulfurtransferase TusA family protein compare
MMP_RS08835 +0.3 2.2 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS01420 +0.3 0.9 hypothetical protein compare
MMP_RS02480 +0.3 1.0 hypothetical protein compare
MMP_RS01180 +0.3 0.3 XTP/dITP diphosphatase compare
MMP_RS05315 +0.3 0.7 hypothetical protein compare
MMP_RS00385 +0.3 1.9 P-II family nitrogen regulator compare
MMP_RS03405 +0.3 1.4 RNA 3'-terminal phosphate cyclase compare
MMP_RS02895 +0.3 1.6 DHH family phosphoesterase compare
MMP_RS07970 +0.3 1.3 hypothetical protein compare
MMP_RS01095 +0.3 1.5 iron ABC transporter permease compare
MMP_RS07840 +0.3 1.2 ribonuclease III compare
MMP_RS08640 +0.3 2.2 TIM barrel protein compare
MMP_RS06480 +0.3 1.8 ABC transporter substrate-binding protein compare
MMP_RS01155 +0.3 1.8 XRE family transcriptional regulator compare
MMP_RS07900 +0.3 0.8 YeeE/YedE family protein compare
MMP_RS07125 +0.3 1.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00080 +0.3 0.9 RecB-family nuclease compare
MMP_RS08480 +0.3 2.0 molybdate ABC transporter substrate-binding protein compare
MMP_RS01515 +0.3 1.9 PINc/VapC family ATPase compare
MMP_RS06520 +0.3 1.8 DUF1786 domain-containing protein compare
MMP_RS08380 +0.3 1.6 phosphatase PAP2 family protein compare
MMP_RS01930 +0.3 1.9 hypothetical protein compare
MMP_RS05140 +0.3 1.1 helix-turn-helix transcriptional regulator compare
MMP_RS03465 +0.3 0.5 adenine phosphoribosyltransferase compare
MMP_RS02790 +0.3 0.5 class III signal peptide-containing protein compare
MMP_RS07100 +0.3 1.8 hypothetical protein compare
MMP_RS00375 +0.2 2.0 ammonium transporter compare
MMP_RS08390 +0.2 1.8 DUF5400 domain-containing protein compare
MMP_RS08355 +0.2 1.2 Na(+)/H(+) antiporter subunit B compare
MMP_RS07120 +0.2 1.8 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06910 +0.2 1.8 RlmF-related methyltransferase compare
MMP_RS06965 +0.2 1.6 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS06430 +0.2 1.5 6-carboxytetrahydropterin synthase QueD compare
MMP_RS09050 +0.2 1.3 CAP domain-containing protein compare
MMP_RS08265 +0.2 0.9 rubrerythrin compare
MMP_RS01485 +0.2 1.6 right-handed parallel beta-helix repeat-containing protein compare
MMP_RS04260 +0.2 1.3 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS06190 +0.2 1.6 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS00395 +0.2 0.6 MGMT family protein compare
MMP_RS06555 +0.2 1.2 cupin domain-containing protein compare
MMP_RS07415 +0.2 1.5 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS08405 +0.2 1.6 MFS transporter compare
MMP_RS02360 +0.2 1.3 hypothetical protein compare
MMP_RS01675 +0.2 0.6 hypothetical protein compare
MMP_RS04730 +0.2 1.5 flavodoxin family protein compare
MMP_RS07590 +0.2 1.7 hypothetical protein compare
MMP_RS02440 +0.2 1.5 hypothetical protein compare
MMP_RS08415 +0.2 0.9 radical SAM protein compare
MMP_RS07155 +0.2 1.5 MFS transporter compare
MMP_RS00635 +0.2 1.3 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS07620 +0.2 1.0 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS05460 +0.2 1.6 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS05355 +0.2 0.3 hypothetical protein compare
MMP_RS07130 +0.2 1.2 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS08830 +0.2 1.1 GTP-binding protein compare
MMP_RS08165 +0.2 0.2 phosphoglycerate dehydrogenase compare
MMP_RS08990 +0.2 0.9 hypothetical protein compare
MMP_RS05275 +0.2 1.6 AI-2E family transporter compare
MMP_RS01540 +0.2 1.0 DUF504 domain-containing protein compare
MMP_RS03965 +0.2 0.7 hypothetical protein compare
MMP_RS07955 +0.2 1.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS03990 +0.2 1.5 recombinase family protein compare
MMP_RS08075 +0.2 1.3 DUF749 domain-containing protein compare
MMP_RS08660 +0.2 1.4 DHH family phosphoesterase compare
MMP_RS00435 +0.2 1.5 CPBP family intramembrane metalloprotease compare
MMP_RS01430 +0.2 1.1 mechanosensitive ion channel family protein compare
MMP_RS03460 +0.2 1.3 U32 family peptidase compare
MMP_RS02680 +0.2 1.3 ABC transporter permease compare
MMP_RS01270 +0.2 1.7 prepilin peptidase compare
MMP_RS09060 +0.2 1.6 hypothetical protein compare
MMP_RS05225 +0.2 1.4 RluA family pseudouridine synthase compare
MMP_RS05970 +0.2 0.9 class II SORL domain-containing protein compare
MMP_RS04165 +0.2 1.1 TetR/AcrR family transcriptional regulator compare
MMP_RS08470 +0.2 1.0 ATP-binding cassette domain-containing protein compare
MMP_RS08235 +0.2 1.2 hypothetical protein compare
MMP_RS08500 +0.2 1.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS00800 +0.2 1.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS04740 +0.2 0.9 DUF473 domain-containing protein compare
MMP_RS01950 +0.2 1.3 hypothetical protein compare
MMP_RS02595 +0.2 0.4 putative zinc-binding protein compare
MMP_RS00830 +0.2 0.6 purine phosphoribosyltransferase family protein compare
MMP_RS00645 +0.2 1.4 iron ABC transporter permease compare
MMP_RS03340 +0.2 0.2 ABC transporter ATP-binding protein compare
MMP_RS07985 +0.2 1.5 nitroreductase family protein compare
MMP_RS01935 +0.2 1.3 DUF58 domain-containing protein compare
MMP_RS00955 +0.2 1.4 coenzyme gamma-F420-2:alpha-L-glutamate ligase compare
MMP_RS00105 +0.2 1.2 hypothetical protein compare
MMP_RS04300 +0.2 1.1 hypothetical protein compare
MMP_RS07680 +0.2 0.7 DUF366 family protein compare
MMP_RS03955 +0.2 1.5 DUF3578 domain-containing protein compare
MMP_RS05935 +0.2 1.3 uroporphyrinogen decarboxylase family protein compare
MMP_RS02570 +0.2 1.5 cation:proton antiporter compare
MMP_RS00125 +0.2 0.4 DUF2798 domain-containing protein compare
MMP_RS05980 +0.2 1.0 ferritin compare
MMP_RS04190 +0.2 1.2 hypothetical protein compare
MMP_RS00400 +0.2 1.1 tributyrin esterase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t2 experiments

For nutrient t2 Sodium acetate across organisms