Experiment set2IT043 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with Cisplatin 0.006 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_337 +1.6 8.0 O-antigen export system permease protein RfbD compare
Pf1N1B4_4830 +1.5 2.5 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_904 +1.5 3.5 DNA-binding protein HU-beta compare
Pf1N1B4_1457 +1.5 11.2 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_1456 +1.5 9.0 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_4826 +1.5 2.7 glutamine synthetase family protein compare
Pf1N1B4_2169 +1.4 3.2 FIG00953808: hypothetical protein compare
Pf1N1B4_5699 +1.4 2.4 ABC-type uncharacterized transport system, ATPase component compare
Pf1N1B4_292 +1.4 13.1 ErfK/YbiS/YcfS/YnhG family protein compare
Pf1N1B4_3129 +1.4 2.3 Prophage baseplate assembly protein V compare
Pf1N1B4_1458 +1.4 8.9 Probable transcription regulator Mig-14 compare
Pf1N1B4_1463 +1.4 9.0 hypothetical protein compare
Pf1N1B4_3692 +1.3 3.9 Chaperone protein HtpG compare
Pf1N1B4_3830 +1.3 3.1 CrfX protein compare
Pf1N1B4_4043 +1.3 3.5 Type II and III secretion system family protein compare
Pf1N1B4_3078 +1.3 2.2 FIG138056: a glutathione-dependent thiol reductase compare
Pf1N1B4_336 +1.3 10.5 Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) compare
Pf1N1B4_1993 +1.3 2.3 C4-type zinc finger protein, DksA/TraR family compare
Pf1N1B4_5611 +1.2 3.2 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) compare
Pf1N1B4_290 +1.2 11.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_291 +1.2 5.3 Major outer membrane lipoprotein I compare
Pf1N1B4_1465 +1.2 9.8 Carbamoyltransferase in large core OS assembly cluster compare
Pf1N1B4_4422 +1.2 2.0 ABC transporter amino acid-binding protein compare
Pf1N1B4_4900 +1.2 2.8 Alkaline proteinase inhibitor precursor compare
Pf1N1B4_749 +1.2 2.5 hypothetical protein compare
Pf1N1B4_4296 +1.1 3.4 Histidine transporter, periplasmic histidine-binding protein compare
Pf1N1B4_4459 +1.1 2.5 Thermostable hemolysin delta-VPH compare
Pf1N1B4_2168 +1.1 5.6 FIG004064: hypothetical protein compare
Pf1N1B4_1430 +1.1 1.6 Predicted signal transduction protein compare
Pf1N1B4_287 +1.1 7.0 Possible periplasmic thiredoxin compare
Pf1N1B4_5924 +1.1 6.1 hypothetical protein compare
Pf1N1B4_3909 +1.1 1.6 Cell division inhibitor-related protein compare
Pf1N1B4_515 +1.0 2.6 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf1N1B4_43 +1.0 4.8 hypothetical protein compare
Pf1N1B4_5005 +1.0 2.6 LysR family transcriptional regulator STM2281 compare
Pf1N1B4_3510 +1.0 4.8 nucleoprotein/polynucleotide-associated enzyme compare
Pf1N1B4_4470 +1.0 2.4 Cobalt-zinc-cadmium resistance protein CzcD compare
Pf1N1B4_197 +1.0 1.1 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_5500 +1.0 5.1 hypothetical protein compare
Pf1N1B4_2117 +1.0 8.2 Ribonuclease PH (EC 2.7.7.56) compare
Pf1N1B4_4814 +1.0 2.4 Iron(III) dicitrate transport system permease protein FecD (TC 3.A.1.14.1) compare
Pf1N1B4_2763 +1.0 3.6 23S rRNA (guanine-N-2-) -methyltransferase rlmG (EC 2.1.1.-) compare
Pf1N1B4_275 +1.0 1.8 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_5430 +1.0 2.0 hypothetical protein compare
Pf1N1B4_4569 +1.0 1.4 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf1N1B4_288 +1.0 6.0 FIG00958794: hypothetical protein compare
Pf1N1B4_3998 +1.0 3.2 putative exported protein compare
Pf1N1B4_483 +1.0 1.6 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_5835 +1.0 1.8 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_5860 +1.0 1.9 Two-component response regulator compare
Pf1N1B4_157 +1.0 2.7 ThiJ/PfpI family protein compare
Pf1N1B4_284 +1.0 7.4 Universal stress protein family compare
Pf1N1B4_4024 +1.0 2.0 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_1584 +0.9 1.7 Histidine ABC transporter, permease protein (TC 3.A.1) compare
Pf1N1B4_293 +0.9 5.3 hypothetical protein compare
Pf1N1B4_2635 +0.9 1.9 hypothetical protein compare
Pf1N1B4_5925 +0.9 6.1 hypothetical protein compare
Pf1N1B4_4355 +0.9 2.1 Gamma-glutamyl-aminobutyraldehyde dehydrogenase (EC 1.2.1.-) compare
Pf1N1B4_5838 +0.9 1.8 FIG00956589: hypothetical protein compare
Pf1N1B4_2163 +0.9 1.5 hypothetical protein compare
Pf1N1B4_909 +0.9 1.8 Ketosteroid isomerase-related protein compare
Pf1N1B4_3549 +0.9 1.6 YciL protein compare
Pf1N1B4_2003 +0.9 4.1 FIG00956226: hypothetical protein compare
Pf1N1B4_5349 +0.9 2.7 hypothetical protein compare
Pf1N1B4_3815 +0.9 3.6 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf1N1B4_3966 +0.9 1.7 serine/threonine protein kinase compare
Pf1N1B4_611 +0.9 2.0 CoA transferase, CAIB/BAIF family compare
Pf1N1B4_4980 +0.9 1.7 putative lipoprotein compare
Pf1N1B4_883 +0.9 1.9 Hypothetical nudix hydrolase YeaB compare
Pf1N1B4_3064 +0.9 2.6 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_3858 +0.9 2.9 FIG00954563: hypothetical protein compare
Pf1N1B4_5926 +0.9 5.2 hypothetical protein compare
Pf1N1B4_3113 +0.9 7.0 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf1N1B4_1469 +0.9 7.4 Heptose kinase WapQ, eukaryotic type compare
Pf1N1B4_289 +0.9 6.8 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf1N1B4_1242 +0.9 3.4 FIG000605: protein co-occurring with transport systems (COG1739) compare
Pf1N1B4_3889 +0.8 1.2 hypothetical protein compare
Pf1N1B4_2441 +0.8 2.8 Electron transfer flavoprotein, alpha subunit compare
Pf1N1B4_3134 +0.8 1.8 probable tail fiber assembly-like protein compare
Pf1N1B4_2380 +0.8 6.1 Cytochrome B561 compare
Pf1N1B4_5311 +0.8 1.6 hypothetical protein compare
Pf1N1B4_4349 +0.8 2.6 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
Pf1N1B4_399 +0.8 1.6 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21) compare
Pf1N1B4_232 +0.8 1.7 DNA-binding response regulator, LuxR family compare
Pf1N1B4_2713 +0.8 2.2 FIG00955339: hypothetical protein compare
Pf1N1B4_4601 +0.8 1.9 Streptothricin acetyltransferase, Streptomyces lavendulae type compare
Pf1N1B4_2694 +0.8 6.2 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf1N1B4_4358 +0.8 1.6 Acetyltransferase, GNAT family compare
Pf1N1B4_4549 +0.8 2.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
Pf1N1B4_4289 +0.8 3.1 Methyl-accepting chemotaxis protein compare
Pf1N1B4_3030 +0.8 3.0 Transcriptional regulators, LysR family compare
Pf1N1B4_5598 +0.8 1.7 hypothetical protein compare
Pf1N1B4_2701 +0.8 7.5 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf1N1B4_5927 +0.8 7.1 Capsular polysaccharide biosynthesis protein compare
Pf1N1B4_267 +0.8 1.8 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf1N1B4_2695 +0.8 1.4 Rare lipoprotein A precursor compare
Pf1N1B4_1008 +0.8 0.8 FIG006045: Sigma factor, ECF subfamily compare
Pf1N1B4_4280 +0.8 1.8 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf1N1B4_3390 +0.8 1.9 RNA polymerase sigma factor RpoE compare
Pf1N1B4_3808 +0.8 3.1 hydrolase, haloacid dehalogenase-like family compare
Pf1N1B4_1535 +0.8 2.7 hypothetical protein compare
Pf1N1B4_1994 +0.8 2.3 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf1N1B4_2381 +0.8 5.9 Protein yceI precursor compare
Pf1N1B4_3224 +0.8 3.7 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
Pf1N1B4_4337 +0.8 1.7 Transcriptional regulator compare
Pf1N1B4_139 +0.8 2.1 Pyoverdin biosynthesis protein PvdN, putative aminotransferase, class V compare
Pf1N1B4_1893 +0.8 2.7 ABC-type transport system involved in resistance to organic solvents, permease component USSDB6A compare
Pf1N1B4_2067 +0.8 2.5 Type VI secretion lipoprotein/VasD compare
Pf1N1B4_1154 +0.8 2.4 FIG00957702: hypothetical protein compare
Pf1N1B4_2993 +0.8 2.2 hypothetical protein compare
Pf1N1B4_138 +0.8 1.3 Putative dipeptidase, pyoverdin biosynthesis PvdM compare
Pf1N1B4_2851 +0.8 1.3 hypothetical protein compare
Pf1N1B4_1466 +0.8 2.7 hypothetical protein compare
Pf1N1B4_3117 +0.8 4.3 DNA mismatch repair protein MutS compare
Pf1N1B4_4402 +0.8 1.7 SoxH protein, homolog compare
Pf1N1B4_124 +0.8 1.6 Mechanosensitive ion channel compare
Pf1N1B4_5082 +0.8 2.2 Capsular polysaccharide synthesis enzyme CpsB compare
Pf1N1B4_2314 +0.8 1.9 FIG028932: hypothetical protein compare
Pf1N1B4_4812 +0.8 2.0 Site-specific recombinase, phage integrase family compare
Pf1N1B4_5568 +0.8 1.6 hypothetical protein compare
Pf1N1B4_1554 +0.7 4.6 predicted FeS cluster maintenance protein (from data) compare
Pf1N1B4_3907 +0.7 1.6 FIG00953287: hypothetical protein compare
Pf1N1B4_1472 +0.7 1.2 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
Pf1N1B4_1668 +0.7 3.8 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_2224 +0.7 1.6 FIG00953390: hypothetical protein compare
Pf1N1B4_3345 +0.7 5.1 Ribonuclease D (EC 3.1.26.3) compare
Pf1N1B4_5024 +0.7 3.3 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf1N1B4_4273 +0.7 2.7 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf1N1B4_4901 +0.7 2.8 ABC-type protease exporter, ATP-binding component PrtD/AprD compare
Pf1N1B4_3926 +0.7 2.0 membrane protein, putative compare
Pf1N1B4_3976 +0.7 3.4 Transmembrane regulator protein PrtR compare
Pf1N1B4_3530 +0.7 2.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf1N1B4_3672 +0.7 2.8 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf1N1B4_340 +0.7 3.0 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_2567 +0.7 4.0 FIG00956941: hypothetical protein compare
Pf1N1B4_1713 +0.7 2.9 Glutamate transport membrane-spanning protein compare
Pf1N1B4_4731 +0.7 1.9 Sigma-54 dependent transcriptional regulator compare
Pf1N1B4_302 +0.7 2.5 Membrane protein, distant similarity to thiosulphate:quinone oxidoreductase DoxD compare
Pf1N1B4_3829 +0.7 5.6 Magnesium and cobalt transport protein CorA compare
Pf1N1B4_2209 +0.7 4.5 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_4975 +0.7 2.2 hypothetical protein compare
Pf1N1B4_5084 +0.7 2.1 Capsular polysaccharide synthesis enzyme CpsD, exopolysaccharide synthesis compare
Pf1N1B4_2739 +0.7 1.1 acetyltransferase, GNAT family compare
Pf1N1B4_3742 +0.7 1.3 Oxidoreductase, zinc-binding compare
Pf1N1B4_4846 +0.7 2.3 Multiple polyol-specific dehydrogenase (EC 1.1.1.-) compare
Pf1N1B4_3263 +0.7 3.0 FIG126011: Hypothetical protein compare
Pf1N1B4_3973 +0.7 2.2 ABC-type spermidine/putrescine transport system, permease component I compare
Pf1N1B4_5711 +0.7 2.0 Salicylate hydroxylase (EC 1.14.13.1) compare
Pf1N1B4_3386 +0.7 2.1 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf1N1B4_4870 +0.7 1.2 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf1N1B4_5567 +0.7 2.4 transcriptional regulator MvaT, P16 subunit, putative compare
Pf1N1B4_2733 +0.7 1.2 DNA polymerase III alpha subunit (EC 2.7.7.7) compare
Pf1N1B4_1346 +0.7 1.9 Urea ABC transporter, ATPase protein UrtD compare
Pf1N1B4_1816 +0.7 4.0 Glutaryl-CoA dehydrogenase (EC 1.3.99.7) compare
Pf1N1B4_5549 +0.7 1.8 hypothetical protein compare
Pf1N1B4_216 +0.7 2.1 Sigma factor PvdS, controling pyoverdin biosynthesis compare
Pf1N1B4_3722 +0.7 2.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_4397 +0.7 1.7 Succinylglutamate desuccinylase/aspartoacylase compare
Pf1N1B4_1418 +0.7 5.2 Epoxyqueuosine (oQ) reductase QueG compare
Pf1N1B4_2948 +0.7 1.4 FIG00954698: hypothetical protein compare
Pf1N1B4_3980 +0.7 1.7 Transcriptional regulator, HxlR family compare
Pf1N1B4_719 +0.7 3.4 Probable Co/Zn/Cd efflux system membrane fusion protein compare
Pf1N1B4_4239 +0.7 1.4 hypothetical protein compare
Pf1N1B4_548 +0.7 2.7 Transcriptional regulator, LysR family compare
Pf1N1B4_1468 +0.7 5.7 InaA protein compare
Pf1N1B4_4392 +0.7 2.0 MocE compare
Pf1N1B4_1135 +0.7 1.6 FIG00960055: hypothetical protein compare
Pf1N1B4_285 +0.7 4.2 5'-nucleotidase (EC 3.1.3.5) compare
Pf1N1B4_4749 +0.7 2.5 ABC transporter ATP-binding protein uup compare
Pf1N1B4_4962 +0.7 1.8 C4-dicarboxylate transport protein compare
Pf1N1B4_296 +0.7 1.8 ABC transporter ATP-binding protein YvcR compare
Pf1N1B4_2866 +0.7 2.1 Periplasmic hemin-binding protein compare
Pf1N1B4_286 +0.7 4.7 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf1N1B4_968 +0.7 2.9 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Pf1N1B4_3927 +0.7 1.0 hypothetical protein compare
Pf1N1B4_5353 +0.7 2.5 hypothetical protein compare
Pf1N1B4_2269 +0.7 1.7 Purine nucleoside phosphorylase (EC 2.4.2.1) compare
Pf1N1B4_3885 +0.7 2.3 Predicted hydrolase of the alpha/beta-hydrolase fold compare
Pf1N1B4_6041 +0.7 1.6 Carbon storage regulator compare
Pf1N1B4_3772 +0.7 2.4 Glutaredoxin compare
Pf1N1B4_295 +0.6 4.5 Arylesterase precursor (EC 3.1.1.2) compare
Pf1N1B4_3816 +0.6 3.4 FIG139976: hypothetical protein compare
Pf1N1B4_4455 +0.6 1.5 FIG00953528: hypothetical protein compare
Pf1N1B4_2731 +0.6 1.1 Uncharacterized protein conserved in bacteria compare
Pf1N1B4_2615 +0.6 3.0 Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1 compare
Pf1N1B4_5476 +0.6 1.8 hypothetical protein compare
Pf1N1B4_3793 +0.6 1.7 COG2010: Cytochrome c, mono- and diheme variants compare
Pf1N1B4_4787 +0.6 2.0 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
Pf1N1B4_3783 +0.6 1.1 FIG00958237: hypothetical protein compare
Pf1N1B4_150 +0.6 1.7 SyrP-like protein compare
Pf1N1B4_53 +0.6 1.9 hypothetical protein compare
Pf1N1B4_16 +0.6 2.1 Cys regulon transcriptional activator CysB compare
Pf1N1B4_2415 +0.6 2.4 TldD family protein, Beta/Gamma-proteobacterial subgroup compare
Pf1N1B4_3413 +0.6 1.2 Transcriptional regulator, LysR family compare
Pf1N1B4_5289 +0.6 1.4 hypothetical protein compare
Pf1N1B4_5306 +0.6 1.5 hypothetical protein compare
Pf1N1B4_1311 +0.6 2.6 Probable transmembrane protein compare
Pf1N1B4_2854 +0.6 2.4 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf1N1B4_3454 +0.6 3.3 Mg/Co/Ni transporter MgtE / CBS domain compare
Pf1N1B4_5435 +0.6 1.9 hypothetical protein compare


Specific Phenotypes

For 8 genes in this experiment

For stress Cisplatin in Pseudomonas fluorescens FW300-N1B4

For stress Cisplatin across organisms