Experiment set2IT043 for Shewanella sp. ANA-3

Compare to:

LB with Cisplatin 0.05 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shewana3_0300 glnA +5.4 7.2 glutamine synthetase (RefSeq) compare
Shewana3_0197 +3.9 2.3 elongation factor Tu (RefSeq) compare
Shewana3_3728 +3.8 7.5 twin arginine-targeting protein translocase (RefSeq) compare
Shewana3_3811 rpoZ +3.3 2.3 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shewana3_1395 +3.2 1.6 putative lipoprotein (RefSeq) compare
Shewana3_2467 +3.2 5.0 hypothetical protein (RefSeq) compare
Shewana3_1005 +3.1 2.6 CBS domain-containing protein (RefSeq) compare
Shewana3_0547 +3.0 1.8 histone family protein DNA-binding protein (RefSeq) compare
Shewana3_3812 +3.0 3.8 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shewana3_1044 deoD +2.9 2.0 purine nucleoside phosphorylase (RefSeq) compare
Shewana3_2110 +2.8 2.3 cytochrome c oxidase, cbb3-type, subunit III (RefSeq) compare
Shewana3_0426 aceE +2.7 7.3 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shewana3_1862 +2.6 2.0 methyl-accepting chemotaxis sensory transducer (RefSeq) compare
Shewana3_3103 +2.5 1.9 rhodanese domain-containing protein (RefSeq) compare
Shewana3_1039 +2.5 4.2 nucleoside permease (cytidine, inosine, uridine, or thymidine) (from data) compare
Shewana3_1757 +2.5 2.4 17 kDa surface antigen (RefSeq) compare
Shewana3_3035 +2.5 3.9 hypothetical protein (RefSeq) compare
Shewana3_2443 +2.5 11.1 heat shock protein 90 (RefSeq) compare
Shewana3_1182 trmB +2.3 1.7 tRNA (guanine-N(7)-)-methyltransferase (RefSeq) compare
Shewana3_1231 +2.3 2.6 hypothetical protein (RefSeq) compare
Shewana3_1498 +2.3 0.9 hypothetical protein (RefSeq) compare
Shewana3_0672 +2.2 5.8 RNA polymerase factor sigma-54 (RefSeq) compare
Shewana3_2107 +2.2 8.2 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shewana3_2402 +2.1 1.0 diacylglycerol kinase (RefSeq) compare
Shewana3_2104 +2.1 2.4 phage integrase family protein (RefSeq) compare
Shewana3_1012 +2.1 6.6 GTP-dependent nucleic acid-binding protein EngD (RefSeq) compare
Shewana3_3509 +2.1 4.2 malate dehydrogenase (RefSeq) compare
Shewana3_2422 +2.1 1.4 hypothetical protein (RefSeq) compare
Shewana3_3569 +2.0 7.2 MATE efflux family protein (RefSeq) compare
Shewana3_0427 +2.0 6.9 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shewana3_1722 +2.0 1.1 prolyl 4-hydroxylase, alpha subunit (RefSeq) compare
Shewana3_1994 +2.0 1.7 outer membrane efflux protein (RefSeq) compare
Shewana3_0602 +2.0 7.8 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shewana3_1946 +1.9 2.2 response regulator receiver protein (RefSeq) compare
Shewana3_0425 pdhR +1.9 3.2 transcriptional regulator PdhR (RefSeq) compare
Shewana3_2780 phhB +1.9 2.1 pterin-4-alpha-carbinolamine dehydratase (RefSeq) compare
Shewana3_1730 +1.9 0.8 hypothetical protein (RefSeq) compare
Shewana3_0041 +1.9 5.0 coproporphyrinogen III oxidase (RefSeq) compare
Shewana3_0148 hslO +1.9 4.4 Hsp33-like chaperonin (RefSeq) compare
Shewana3_2817 +1.9 8.6 PII uridylyl-transferase (RefSeq) compare
Shewana3_2120 +1.9 2.5 hypothetical protein (RefSeq) compare
Shewana3_3730 +1.8 5.2 Sec-independent protein translocase TatC (RefSeq) compare
Shewana3_2112 +1.8 4.2 heavy metal translocating P-type ATPase (RefSeq) compare
Shewana3_0258 +1.8 9.0 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shewana3_3022 acpS +1.8 2.7 4'-phosphopantetheinyl transferase (RefSeq) compare
Shewana3_2867 +1.8 1.6 Fmu (Sun) domain-containing protein (RefSeq) compare
Shewana3_0825 +1.8 3.5 hypothetical protein (RefSeq) compare
Shewana3_3350 +1.8 7.5 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shewana3_1736 +1.8 3.7 phosphoenolpyruvate synthase (RefSeq) compare
Shewana3_2382 minC +1.8 2.6 septum formation inhibitor (RefSeq) compare
Shewana3_2589 +1.8 2.4 type IV pilus assembly PilZ (RefSeq) compare
Shewana3_3019 +1.7 2.9 cytochrome c assembly protein (RefSeq) compare
Shewana3_1528 +1.7 2.6 short chain dehydrogenase (RefSeq) compare
Shewana3_0259 +1.7 7.0 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shewana3_2896 +1.7 8.1 thiamine biosynthesis protein ThiI (RefSeq) compare
Shewana3_0505 fre +1.7 8.5 FMN reductase (RefSeq) compare
Shewana3_2384 minE +1.7 2.4 cell division topological specificity factor MinE (RefSeq) compare
Shewana3_2281 +1.7 5.0 BadM/Rrf2 family transcriptional regulator (RefSeq) compare
Shewana3_2466 +1.7 2.4 anti-ECFsigma factor, ChrR (RefSeq) compare
Shewana3_1691 +1.6 1.3 LysR family transcriptional regulator (RefSeq) compare
Shewana3_2394 +1.6 3.3 2OG-Fe(II) oxygenase (RefSeq) compare
Shewana3_2122 +1.6 2.0 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shewana3_2480 +1.6 2.5 LysR family transcriptional regulator (RefSeq) compare
Shewana3_2400 +1.6 1.9 hypothetical protein (RefSeq) compare
Shewana3_1686 +1.6 1.3 1,4-dihydroxy-2-naphtoate prenyltransferase (RefSeq) compare
Shewana3_2149 +1.6 1.0 phosphogluconate dehydratase (RefSeq) compare
Shewana3_3408 panB +1.6 7.5 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) compare
Shewana3_2295 +1.6 2.1 L-serine ammonia-lyase (RefSeq) compare
Shewana3_0005 trmE +1.6 3.9 tRNA modification GTPase TrmE (RefSeq) compare
Shewana3_1775 +1.6 3.0 YebG family protein (RefSeq) compare
Shewana3_0820 +1.6 4.2 SH3 type 3 domain-containing protein (RefSeq) compare
Shewana3_1435 tgt +1.5 2.8 queuine tRNA-ribosyltransferase (RefSeq) compare
Shewana3_2990 +1.5 2.7 hypothetical protein (RefSeq) compare
Shewana3_2292 +1.5 2.7 hypothetical protein (RefSeq) compare
Shewana3_2519 +1.5 0.5 biotin synthase (RefSeq) compare
Shewana3_2175 +1.5 0.7 phage integrase family protein (RefSeq) compare
Shewana3_0235 +1.5 4.5 periplasmic protein thiol--disulphide oxidoreductase DsbE (RefSeq) compare
Shewana3_1894 +1.5 2.3 surface antigen (D15) (RefSeq) compare
Shewana3_2399 +1.5 3.0 protein tyrosine phosphatase (RefSeq) compare
Shewana3_1809 +1.5 3.2 hypothetical protein (RefSeq) compare
Shewana3_0154 +1.5 2.4 general secretion pathway protein G (RefSeq) compare
Shewana3_1934 +1.5 2.2 hemolysin III family channel protein (RefSeq) compare
Shewana3_0780 +1.4 5.7 2-dehydropantoate 2-reductase (RefSeq) compare
Shewana3_2118 +1.4 2.0 hypothetical protein (RefSeq) compare
Shewana3_2448 +1.4 2.4 hypothetical protein (RefSeq) compare
Shewana3_2453 +1.4 1.1 TraR/DksA family transcriptional regulator (RefSeq) compare
Shewana3_2794 +1.4 1.2 putative hydrolase (RefSeq) compare
Shewana3_1996 +1.4 0.8 phage integrase family protein (RefSeq) compare
Shewana3_1368 +1.4 1.2 hypothetical protein (RefSeq) compare
Shewana3_2541 +1.4 4.9 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen (RefSeq) compare
Shewana3_2544 upp +1.4 3.4 uracil phosphoribosyltransferase (RefSeq) compare
Shewana3_1823 +1.4 2.3 hypothetical protein (RefSeq) compare
Shewana3_1718 +1.4 1.0 hypothetical protein (RefSeq) compare
Shewana3_2405 +1.4 1.1 alpha-L-glutamate ligase (RefSeq) compare
Shewana3_3359 +1.4 1.4 GGDEF domain-containing protein (RefSeq) compare
Shewana3_2133 +1.4 1.2 peptide methionine sulfoxide reductase (RefSeq) compare
Shewana3_1938 +1.4 1.5 UBA/THIF-type NAD/FAD binding protein (RefSeq) compare
Shewana3_2594 +1.4 0.5 putative two-component response-regulatory protein YehT (RefSeq) compare
Shewana3_1450 +1.4 2.3 membrane protein involved in aromatic hydrocarbon degradation (RefSeq) compare
Shewana3_0603 +1.4 3.1 cytochrome c1 (RefSeq) compare
Shewana3_1956 ruvA +1.4 1.5 Holliday junction DNA helicase RuvA (RefSeq) compare
Shewana3_1903 +1.4 2.2 restriction endonuclease (RefSeq) compare
Shewana3_3493 +1.4 3.5 hypothetical protein (RefSeq) compare
Shewana3_1648 +1.3 0.7 arsenate reductase (RefSeq) compare
Shewana3_1612 +1.3 1.6 hypothetical protein (RefSeq) compare
Shewana3_1561 +1.3 3.9 cysteine synthase (RefSeq) compare
Shewana3_3382 +1.3 1.7 hypothetical protein (RefSeq) compare
Shewana3_2460 +1.3 2.8 hypothetical protein (RefSeq) compare
Shewana3_2178 +1.3 1.2 hypothetical protein (RefSeq) compare
Shewana3_2898 +1.3 2.4 flagellar motor protein PomA (RefSeq) compare
Shewana3_2021 +1.3 3.4 metal dependent phosphohydrolase (RefSeq) compare
Shewana3_3146 +1.3 2.2 OmpA/MotB domain-containing protein (RefSeq) compare
Shewana3_1333 +1.3 4.6 flagellin domain-containing protein (RefSeq) compare
Shewana3_0158 +1.3 6.4 general secretion pathway protein K (RefSeq) compare
Shewana3_0717 +1.3 2.6 putative hydroxylase (RefSeq) compare
Shewana3_2566 +1.3 1.2 ribosomal large subunit pseudouridine synthase C (RefSeq) compare
Shewana3_1337 fliS +1.3 6.7 flagellar protein FliS (RefSeq) compare
Shewana3_1873 +1.3 1.7 formate dehydrogenase family accessory protein FdhD (RefSeq) compare
Shewana3_0656 +1.3 1.3 two component LuxR family transcriptional regulator (RefSeq) compare
Shewana3_2363 +1.3 3.1 cytochrome c552 (RefSeq) compare
Shewana3_2447 +1.3 2.7 adenine phosphoribosyltransferase (RefSeq) compare
Shewana3_1585 cpdB +1.3 3.4 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (RefSeq) compare
Shewana3_R0102 +1.3 3.0 tRNA-Pro (RefSeq) compare
Shewana3_1299 +1.3 2.3 hypothetical protein (RefSeq) compare
Shewana3_3576 dipZ +1.3 6.0 thiol:disulfide interchange protein precursor (RefSeq) compare
Shewana3_3815 +1.2 4.8 CaCA family Na(+)/Ca(+) antiporter (RefSeq) compare
Shewana3_2211 +1.2 0.9 NERD domain-containing protein (RefSeq) compare
Shewana3_2498 +1.2 3.3 nicotinamide mononucleotide transporter PnuC (RefSeq) compare
Shewana3_2737 +1.2 3.1 putative esterase (RefSeq) compare
Shewana3_2398 +1.2 0.5 hypothetical protein (RefSeq) compare
Shewana3_2199 +1.2 1.1 hypothetical protein (RefSeq) compare
Shewana3_2181 +1.2 3.8 hypothetical protein (RefSeq) compare
Shewana3_0152 +1.2 6.7 type II secretion system protein E (GspE) (RefSeq) compare
Shewana3_1803 +1.2 1.7 hypothetical protein (RefSeq) compare
Shewana3_3465 +1.2 5.5 agmatine deiminase (RefSeq) compare
Shewana3_2662 tig +1.2 3.8 trigger factor (RefSeq) compare
Shewana3_0232 +1.2 5.8 cytochrome c, class I (RefSeq) compare
Shewana3_2891 +1.2 1.8 putative RNA 2'-O-ribose methyltransferase (RefSeq) compare
Shewana3_0002 +1.2 2.8 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA (RefSeq) compare
Shewana3_2601 +1.2 2.7 hypothetical protein (RefSeq) compare
Shewana3_0724 +1.2 3.1 hypothetical protein (RefSeq) compare
Shewana3_2283 +1.2 1.0 RNA methyltransferase (RefSeq) compare
Shewana3_0156 +1.2 1.6 general secretion pathway protein I (RefSeq) compare
Shewana3_1331 flgL +1.2 2.6 flagellar hook-associated protein FlgL (RefSeq) compare
Shewana3_1904 +1.2 0.6 GCN5-related N-acetyltransferase (RefSeq) compare
Shewana3_0014 +1.2 1.2 transcriptional regulator (RefSeq) compare
Shewana3_2352 +1.2 1.1 hypothetical protein (RefSeq) compare
Shewana3_2469 +1.2 1.6 hypothetical protein (RefSeq) compare
Shewana3_0567 +1.2 2.6 ABC-3 protein (RefSeq) compare
Shewana3_1954 +1.2 0.9 hypothetical protein (RefSeq) compare
Shewana3_1755 +1.2 1.5 arginyl-tRNA-protein transferase (RefSeq) compare
Shewana3_0160 +1.2 4.4 general secretion pathway M protein (RefSeq) compare
Shewana3_4062 +1.2 2.5 hypothetical protein (RefSeq) compare
Shewana3_1040 +1.2 2.0 nucleoside-specific channel-forming protein, Tsx (RefSeq) compare
Shewana3_2160 +1.2 0.8 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) (RefSeq) compare
Shewana3_0591 +1.2 1.8 hypothetical protein (RefSeq) compare
Shewana3_1773 +1.2 0.7 paraquat-inducible protein A (RefSeq) compare
Shewana3_2455 +1.2 2.7 phospholipase/carboxylesterase (RefSeq) compare
Shewana3_0234 +1.2 5.3 cytochrome c-type biogenesis protein CcmF (RefSeq) compare
Shewana3_2019 +1.2 2.6 hypothetical protein (RefSeq) compare
Shewana3_1807 +1.2 1.5 hypothetical protein (RefSeq) compare
Shewana3_3124 +1.2 2.3 nitrogen regulatory protein P-II (RefSeq) compare
Shewana3_2429 +1.2 2.1 NADH:flavin oxidoreductase/NADH oxidase (RefSeq) compare
Shewana3_R0122 +1.1 5.2 tRNA-Leu (RefSeq) compare
Shewana3_2167 +1.1 2.3 diguanylate cyclase/phosphodiesterase (RefSeq) compare
Shewana3_2720 +1.1 2.6 hypothetical protein (RefSeq) compare
Shewana3_3030 +1.1 5.5 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shewana3_1236 guaA +1.1 3.7 GMP synthase (RefSeq) compare
Shewana3_1134 +1.1 2.3 cytochrome B561 (RefSeq) compare
Shewana3_1583 +1.1 2.0 D,D-heptose 1,7-bisphosphate phosphatase (RefSeq) compare
Shewana3_0149 +1.1 1.8 RNA-binding S4 domain-containing protein (RefSeq) compare
Shewana3_3224 +1.1 2.0 lysine exporter protein LysE/YggA (RefSeq) compare
Shewana3_2073 +1.1 1.2 L-arabinose ABC transporter, substrate-binding component AraU (from data) compare
Shewana3_3001 +1.1 1.7 hypothetical protein (RefSeq) compare
Shewana3_4144 +1.1 2.1 plastocyanin domain-containing protein (RefSeq) compare
Shewana3_2147 +1.1 0.7 deoxyguanosinetriphosphate triphosphohydrolase-like protein (RefSeq) compare
Shewana3_3505 +1.1 5.7 cell division protein ZapA (RefSeq) compare
Shewana3_1770 yebU +1.1 0.6 rRNA (cytosine-C(5)-)-methyltransferase RsmF (RefSeq) compare
Shewana3_1502 +1.1 1.1 hypothetical protein (RefSeq) compare
Shewana3_0399 +1.1 4.9 nifR3 family TIM-barrel protein (RefSeq) compare
Shewana3_0716 +1.1 6.4 TonB-dependent siderophore receptor (RefSeq) compare
Shewana3_3722 +1.1 1.9 uroporphyrinogen decarboxylase (RefSeq) compare
Shewana3_4211 +1.1 7.7 hypothetical protein (RefSeq) compare
Shewana3_1932 +1.1 1.0 hypothetical protein (RefSeq) compare
Shewana3_0159 +1.1 6.1 general secretion pathway protein L (RefSeq) compare
Shewana3_2114 +1.1 1.6 hypothetical protein (RefSeq) compare
Shewana3_1359 fliA +1.1 2.3 flagellar biosynthesis sigma factor (RefSeq) compare
Shewana3_1793 +1.1 1.9 hypothetical protein (RefSeq) compare
Shewana3_1794 +1.1 3.3 hypothetical protein (RefSeq) compare
Shewana3_1616 +1.1 3.2 hypothetical protein (RefSeq) compare
Shewana3_2915 +1.1 3.9 phage integrase family protein (RefSeq) compare
Shewana3_1192 +1.1 0.5 protein of unknown function YGGT (RefSeq) compare
Shewana3_1723 +1.1 1.1 ATPase domain-containing protein (RefSeq) compare
Shewana3_3249 +1.1 2.2 UspA domain-containing protein (RefSeq) compare
Shewana3_2202 +1.1 1.3 XRE family transcriptional regulator (RefSeq) compare
Shewana3_2029 +1.1 1.0 hypothetical protein (RefSeq) compare
Shewana3_2088 +1.1 1.4 L-arabinolactonase (EC 3.1.1.15) (from data) compare
Shewana3_2607 +1.1 1.3 hypothetical protein (RefSeq) compare
Shewana3_1487 +1.1 1.8 porin (RefSeq) compare
Shewana3_0161 +1.1 3.8 type II secretion system protein N (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Cisplatin in Shewanella sp. ANA-3

For stress Cisplatin across organisms