Experiment set2IT042 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with Thallium(I) acetate 0.008 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_5820 +2.6 9.2 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_866 +2.3 5.4 Iron-sulfur cluster regulator IscR compare
Pf1N1B4_2173 +2.1 5.0 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf1N1B4_1307 +1.9 5.0 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_4830 +1.6 2.7 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_3078 +1.5 2.7 FIG138056: a glutathione-dependent thiol reductase compare
Pf1N1B4_5924 +1.5 8.8 hypothetical protein compare
Pf1N1B4_4422 +1.5 2.6 ABC transporter amino acid-binding protein compare
Pf1N1B4_3246 +1.4 5.4 RND efflux system, inner membrane transporter CmeB compare
Pf1N1B4_5926 +1.4 9.3 hypothetical protein compare
Pf1N1B4_1430 +1.4 2.2 Predicted signal transduction protein compare
Pf1N1B4_3153 +1.3 2.0 hypothetical protein compare
Pf1N1B4_5917 +1.3 2.7 Multimeric flavodoxin WrbA compare
Pf1N1B4_2283 +1.3 1.9 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_4054 +1.3 6.0 ATP-dependent Clp protease adaptor protein ClpS compare
Pf1N1B4_5925 +1.3 8.7 hypothetical protein compare
Pf1N1B4_4799 +1.2 2.2 Multidrug resistance protein B compare
Pf1N1B4_2419 +1.2 6.4 High-affinity choline uptake protein BetT conserved
Pf1N1B4_262 +1.2 10.1 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf1N1B4_4168 +1.2 2.4 putative membrane protein compare
Pf1N1B4_4824 +1.1 2.4 Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) compare
Pf1N1B4_2823 +1.1 2.3 COG1496: Uncharacterized conserved protein compare
Pf1N1B4_1780 +1.1 3.0 FIG00961586: hypothetical protein compare
Pf1N1B4_4459 +1.1 2.0 Thermostable hemolysin delta-VPH compare
Pf1N1B4_324 +1.1 2.4 Glycosyl transferase, group 2 family protein compare
Pf1N1B4_4317 +1.1 0.9 DNA/RNA non-specific endonuclease compare
Pf1N1B4_4043 +1.1 2.8 Type II and III secretion system family protein compare
Pf1N1B4_3446 +1.0 1.8 Putative GTPases (G3E family) compare
Pf1N1B4_2674 +1.0 2.0 hypothetical protein compare
Pf1N1B4_4462 +1.0 1.9 LysR family transcriptional regulator YbhD compare
Pf1N1B4_5239 +1.0 2.4 hypothetical protein compare
Pf1N1B4_2635 +1.0 2.2 hypothetical protein compare
Pf1N1B4_3549 +1.0 1.9 YciL protein compare
Pf1N1B4_2380 +1.0 7.8 Cytochrome B561 compare
Pf1N1B4_629 +1.0 2.1 Queuosine Biosynthesis QueE Radical SAM compare
Pf1N1B4_4478 +1.0 1.5 Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) compare
Pf1N1B4_2854 +1.0 3.5 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf1N1B4_399 +1.0 2.1 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21) compare
Pf1N1B4_4192 +1.0 2.6 Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase compare
Pf1N1B4_338 +1.0 2.5 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_740 +1.0 2.0 Leucyl-tRNA synthetase compare
Pf1N1B4_3152 +0.9 4.9 LysR family transcriptional regulator PA3398 compare
Pf1N1B4_5342 +0.9 2.2 hypothetical protein compare
Pf1N1B4_4751 +0.9 2.6 Ku domain protein compare
Pf1N1B4_636 +0.9 3.2 4-hydroxybenzoyl-CoA thioesterase family active site compare
Pf1N1B4_2047 +0.9 2.5 Chorismate--pyruvate lyase (EC 4.1.3.40) compare
Pf1N1B4_5957 +0.9 2.1 Arsenical resistance operon repressor compare
Pf1N1B4_138 +0.9 1.3 Putative dipeptidase, pyoverdin biosynthesis PvdM compare
Pf1N1B4_339 +0.9 2.0 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf1N1B4_5912 +0.9 2.4 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_4812 +0.9 2.9 Site-specific recombinase, phage integrase family compare
Pf1N1B4_4540 +0.9 1.0 Uncharacterized protein ImpJ/VasE compare
Pf1N1B4_5927 +0.9 7.8 Capsular polysaccharide biosynthesis protein compare
Pf1N1B4_5005 +0.9 2.2 LysR family transcriptional regulator STM2281 compare
Pf1N1B4_1906 +0.9 3.1 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_733 +0.9 1.3 Methionyl-tRNA synthetase (EC 6.1.1.10) compare
Pf1N1B4_2241 +0.9 4.1 Adenylate cyclase (EC 4.6.1.1) compare
Pf1N1B4_1279 +0.9 2.1 Flp pilus assembly protein TadB compare
Pf1N1B4_2067 +0.9 2.7 Type VI secretion lipoprotein/VasD compare
Pf1N1B4_4219 +0.9 1.8 FIG01074225: hypothetical protein compare
Pf1N1B4_909 +0.8 1.6 Ketosteroid isomerase-related protein compare
Pf1N1B4_5745 +0.8 1.3 FIG139928: Putative protease compare
Pf1N1B4_617 +0.8 1.5 Carbamate kinase (EC 2.7.2.2) compare
Pf1N1B4_5306 +0.8 2.2 hypothetical protein compare
Pf1N1B4_5886 +0.8 2.9 Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) compare
Pf1N1B4_4960 +0.8 1.5 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf1N1B4_4972 +0.8 1.8 CELL PROCESSES; Adaptation; adaptations, atypical conditions compare
Pf1N1B4_2381 +0.8 6.5 Protein yceI precursor compare
Pf1N1B4_3352 +0.8 2.4 tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34) compare
Pf1N1B4_649 +0.8 2.9 Small-conductance mechanosensitive channel compare
Pf1N1B4_1312 +0.8 2.7 hypothetical protein compare
Pf1N1B4_1332 +0.8 2.0 Cobalt-precorrin-6 synthase, anaerobic compare
Pf1N1B4_1671 +0.8 2.3 FIG00954962: hypothetical protein compare
Pf1N1B4_3980 +0.8 2.1 Transcriptional regulator, HxlR family compare
Pf1N1B4_696 +0.8 3.4 Acetolactate synthase, large subunit (EC 2.2.1.6) compare
Pf1N1B4_3672 +0.8 3.2 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf1N1B4_230 +0.8 1.3 FIG00953472: hypothetical protein compare
Pf1N1B4_554 +0.8 2.7 Putative threonine efflux protein compare
Pf1N1B4_2983 +0.8 2.2 hypothetical protein compare
Pf1N1B4_175 +0.8 1.6 sigma-54 dependent transcriptional regulator compare
Pf1N1B4_232 +0.8 1.8 DNA-binding response regulator, LuxR family compare
Pf1N1B4_1464 +0.7 4.9 Glycosyl transferase compare
Pf1N1B4_2791 +0.7 2.0 Putative inner membrane protein (Fragment) compare
Pf1N1B4_561 +0.7 1.9 Glutathione S-transferase (EC 2.5.1.18) compare
Pf1N1B4_124 +0.7 1.5 Mechanosensitive ion channel compare
Pf1N1B4_2249 +0.7 1.7 Alkanesulfonate monooxygenase (EC 1.14.14.5) compare
Pf1N1B4_240 +0.7 1.0 Transcriptional regulators compare
Pf1N1B4_2526 +0.7 6.2 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_3973 +0.7 2.3 ABC-type spermidine/putrescine transport system, permease component I compare
Pf1N1B4_4777 +0.7 2.1 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf1N1B4_4455 +0.7 1.6 FIG00953528: hypothetical protein compare
Pf1N1B4_1339 +0.7 2.3 ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component compare
Pf1N1B4_2640 +0.7 2.4 FIG003461: hypothetical protein compare
Pf1N1B4_1263 +0.7 2.0 Cu(I)-responsive transcriptional regulator compare
Pf1N1B4_5078 +0.7 1.5 Transcriptional regulator PhnF compare
Pf1N1B4_5827 +0.7 2.1 Na(+) H(+) antiporter subunit G compare
Pf1N1B4_1472 +0.7 1.1 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
Pf1N1B4_1535 +0.7 2.5 hypothetical protein compare
Pf1N1B4_4814 +0.7 1.1 Iron(III) dicitrate transport system permease protein FecD (TC 3.A.1.14.1) compare
Pf1N1B4_3466 +0.7 1.6 FIG00955605: hypothetical protein compare
Pf1N1B4_4906 +0.7 2.6 Lipase (EC 3.1.1.3) compare
Pf1N1B4_4829 +0.7 2.1 Membrane protein, putative compare
Pf1N1B4_2359 +0.7 1.9 Chemotaxis signal transduction protein compare
Pf1N1B4_5884 +0.7 1.3 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf1N1B4_2060 +0.7 1.8 hypothetical protein compare
Pf1N1B4_2731 +0.7 1.4 Uncharacterized protein conserved in bacteria compare
Pf1N1B4_5378 +0.7 2.0 Phage protein compare
Pf1N1B4_340 +0.7 3.7 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_3795 +0.7 1.1 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_1458 +0.7 3.9 Probable transcription regulator Mig-14 compare
Pf1N1B4_3044 +0.7 2.0 Putative lipoprotein, specific for Pseudomonas, in cluster with COG2110 compare
Pf1N1B4_516 +0.7 1.4 Sensor histidine kinase compare
Pf1N1B4_539 +0.7 1.5 Transcriptional regulators compare
Pf1N1B4_4024 +0.7 1.3 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_4433 +0.7 1.1 FIG035246: DoxX family protein compare
Pf1N1B4_4151 +0.7 2.3 FIG00960153: hypothetical protein compare
Pf1N1B4_3804 +0.7 2.4 Glycine-rich cell wall structural protein precursor compare
Pf1N1B4_3263 +0.7 2.8 FIG126011: Hypothetical protein compare
Pf1N1B4_4725 +0.7 1.9 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) compare
Pf1N1B4_2863 +0.7 3.2 Valine--pyruvate aminotransferase (EC 2.6.1.66) compare
Pf1N1B4_1313 +0.7 3.4 tRNA dihydrouridine synthase B (EC 1.-.-.-) compare
Pf1N1B4_4976 +0.7 1.5 D-serine/D-alanine/glycine transporter compare
Pf1N1B4_3630 +0.7 2.1 Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) compare
Pf1N1B4_2372 +0.7 2.3 Transcriptional regulator, LysR family compare
Pf1N1B4_3777 +0.7 2.3 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p compare
Pf1N1B4_2486 +0.7 1.5 hypothetical protein compare
Pf1N1B4_4249 +0.7 2.3 transcriptional regulator, LuxR family compare
Pf1N1B4_5289 +0.6 1.5 hypothetical protein compare
Pf1N1B4_3413 +0.6 1.2 Transcriptional regulator, LysR family compare
Pf1N1B4_4023 +0.6 2.1 hypothetical protein compare
Pf1N1B4_4296 +0.6 1.9 Histidine transporter, periplasmic histidine-binding protein compare
Pf1N1B4_131 +0.6 1.4 hypothetical protein compare
Pf1N1B4_108 +0.6 1.6 FIG00954456: hypothetical protein compare
Pf1N1B4_3468 +0.6 1.4 Negative regulator of flagellin synthesis FlgM compare
Pf1N1B4_3610 +0.6 2.9 Serine phosphatase RsbU, regulator of sigma subunit compare
Pf1N1B4_1612 +0.6 1.4 FIG00955429: hypothetical protein compare
Pf1N1B4_5261 +0.6 1.3 hypothetical protein compare
Pf1N1B4_5645 +0.6 1.7 Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2) compare
Pf1N1B4_4552 +0.6 2.6 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
Pf1N1B4_4017 +0.6 1.3 DNA-binding heavy metal response regulator compare
Pf1N1B4_675 +0.6 1.4 hypothetical protein compare
Pf1N1B4_239 +0.6 1.5 Similar to ribosomal large subunit pseudouridine synthase A compare
Pf1N1B4_4822 +0.6 1.3 Paraquat-inducible protein A compare
Pf1N1B4_2713 +0.6 1.6 FIG00955339: hypothetical protein compare
Pf1N1B4_228 +0.6 1.6 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Pf1N1B4_3966 +0.6 1.6 serine/threonine protein kinase compare
Pf1N1B4_1891 +0.6 1.1 ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C compare
Pf1N1B4_3900 +0.6 2.3 Universal stress protein family COG0589 compare
Pf1N1B4_4404 +0.6 1.8 Transcriptional regulator, LysR family compare
Pf1N1B4_611 +0.6 1.2 CoA transferase, CAIB/BAIF family compare
Pf1N1B4_3984 +0.6 2.6 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) compare
Pf1N1B4_3786 +0.6 2.1 FIG00955145: hypothetical protein compare
Pf1N1B4_2939 +0.6 2.7 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf1N1B4_5822 +0.6 3.0 Na(+) H(+) antiporter subunit A / Na(+) H(+) antiporter subunit B compare
Pf1N1B4_2739 +0.6 1.0 acetyltransferase, GNAT family compare
Pf1N1B4_3501 +0.6 2.6 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_973 +0.6 5.3 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf1N1B4_5598 +0.6 1.7 hypothetical protein compare
Pf1N1B4_4377 +0.6 2.0 Cell wall hydrolyses involved in spore germination compare
Pf1N1B4_5725 +0.6 0.9 High-affinity iron permease compare
Pf1N1B4_1697 +0.6 2.5 Acyl-CoA dehydrogenase; probable dibenzothiophene desulfurization enzyme compare
Pf1N1B4_972 +0.6 5.3 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf1N1B4_4140 +0.6 1.6 hypothetical protein compare
Pf1N1B4_1963 +0.6 2.2 O-antigen export system permease protein RfbD compare
Pf1N1B4_1036 +0.6 2.3 Signal transduction histidine kinase compare
Pf1N1B4_150 +0.6 1.5 SyrP-like protein compare
Pf1N1B4_4912 +0.6 1.9 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf1N1B4_1194 +0.6 1.6 hypothetical protein compare
Pf1N1B4_3802 +0.6 1.2 PlcB, ORFX, ORFP, ORFB, ORFA, ldh gene compare
Pf1N1B4_483 +0.6 1.1 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_1338 +0.6 2.4 Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB compare
Pf1N1B4_3783 +0.6 1.3 FIG00958237: hypothetical protein compare
Pf1N1B4_970 +0.6 4.5 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf1N1B4_1485 +0.6 1.3 FIG00963848: hypothetical protein compare
Pf1N1B4_971 +0.6 4.6 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf1N1B4_1838 +0.6 1.9 FIG00955509: hypothetical protein compare
Pf1N1B4_5151 +0.6 1.2 FIG002283: Isochorismatase family protein compare
Pf1N1B4_4190 +0.6 2.8 transcriptional regulator, AraC family compare
Pf1N1B4_2392 +0.6 2.1 Cytochrome c556 compare
Pf1N1B4_4602 +0.6 1.2 Transcriptional regulators, LysR family compare
Pf1N1B4_5040 +0.6 1.8 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf1N1B4_3889 +0.6 0.8 hypothetical protein compare
Pf1N1B4_3722 +0.6 1.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_5972 +0.6 1.1 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) compare
Pf1N1B4_2447 +0.6 2.2 GbcA Glycine betaine demethylase subunit A compare
Pf1N1B4_1128 +0.6 1.3 hypothetical protein compare
Pf1N1B4_3235 +0.6 2.0 Protocatechuate 3,4-dioxygenase beta chain (EC 1.13.11.3) compare
Pf1N1B4_5095 +0.6 1.0 hypothetical protein compare
Pf1N1B4_4931 +0.6 1.2 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.79) compare
Pf1N1B4_4870 +0.6 0.8 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf1N1B4_1094 +0.6 1.4 FIG005080: Possible exported protein compare
Pf1N1B4_1146 +0.6 3.6 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components (from data) compare
Pf1N1B4_441 +0.6 0.9 hypothetical protein compare
Pf1N1B4_1276 +0.6 1.5 Flp pilus assembly protein RcpC/CpaB compare
Pf1N1B4_5965 +0.6 1.5 D-amino-acid oxidase (EC 1.4.3.3) compare
Pf1N1B4_4560 +0.6 1.1 Transcriptional regulator, MerR family compare
Pf1N1B4_4076 +0.6 1.0 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf1N1B4_3926 +0.5 1.5 membrane protein, putative compare
Pf1N1B4_5124 +0.5 1.9 two component transcriptional regulator, LuxR family compare
Pf1N1B4_2373 +0.5 2.2 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare


Specific Phenotypes

For 6 genes in this experiment

For stress Thallium(I) acetate in Pseudomonas fluorescens FW300-N1B4

For stress Thallium(I) acetate across organisms