Experiment set2IT039 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with Cisplatin 0.006 mg/ml

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_5618 -3.6 -3.4 Excinuclease ABC subunit C compare
Pf1N1B4_2005 -3.5 -2.4 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_1180 -2.9 -2.5 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_26 -2.9 -8.0 Excinuclease ABC subunit B compare
Pf1N1B4_890 -2.9 -2.7 DNA recombination and repair protein RecO compare
Pf1N1B4_3864 -2.7 -7.2 Recombination protein RecR compare
Pf1N1B4_2874 -2.7 -2.5 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_3091 -2.6 -5.2 Membrane-associated zinc metalloprotease compare
Pf1N1B4_3965 -2.6 -2.5 FIG033889: YebC paralog in Betaproteobacteria compare
Pf1N1B4_1927 -2.5 -8.3 DNA recombination and repair protein RecF conserved
Pf1N1B4_2611 -2.4 -12.5 Excinuclease ABC subunit A conserved
Pf1N1B4_3916 -2.3 -11.4 Transcription-repair coupling factor conserved
Pf1N1B4_3483 -2.2 -5.4 Transcriptional regulatory protein PhoP compare
Pf1N1B4_2105 -2.2 -3.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_5224 -2.2 -2.8 tRNA-Arg-CCT compare
Pf1N1B4_2791 -2.2 -2.8 Putative inner membrane protein (Fragment) compare
Pf1N1B4_2283 -2.2 -2.1 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf1N1B4_4640 -2.2 -5.3 MoxR-like ATPase in aerotolerance operon compare
Pf1N1B4_3812 -2.1 -8.7 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_2493 -2.1 -3.6 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_2682 -2.1 -2.6 Antiholin-like protein LrgA compare
Pf1N1B4_1624 -2.1 -9.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_1626 -2.1 -7.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_3447 -2.0 -5.6 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf1N1B4_4934 -2.0 -6.7 DNA damage response nuclease (from data) conserved
Pf1N1B4_4636 -2.0 -2.8 TPR domain protein in aerotolerance operon compare
Pf1N1B4_5278 -1.9 -2.5 hypothetical protein compare
Pf1N1B4_1234 -1.9 -4.3 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_4040 -1.9 -3.6 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
Pf1N1B4_1403 -1.9 -7.4 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_769 -1.9 -7.5 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_1627 -1.9 -5.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2959 -1.8 -5.4 FIG067310: hypothetical protein compare
Pf1N1B4_3143 -1.8 -2.8 RecA protein compare
Pf1N1B4_2768 -1.8 -4.4 DNA repair protein RadA compare
Pf1N1B4_3590 -1.8 -6.7 hypothetical protein compare
Pf1N1B4_2352 -1.8 -6.2 Glutathione synthetase (EC 6.3.2.3) compare
Pf1N1B4_722 -1.8 -1.6 SAM-dependent methyltransferases compare
Pf1N1B4_4935 -1.7 -5.5 DinG family ATP-dependent helicase CPE1197 conserved
Pf1N1B4_967 -1.7 -2.4 hypothetical protein compare
Pf1N1B4_3605 -1.7 -2.6 Flagellar motor switch protein FliG compare
Pf1N1B4_2888 -1.6 -4.0 FIG00961017: hypothetical protein compare
Pf1N1B4_4123 -1.6 -1.9 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf1N1B4_5450 -1.6 -8.6 Error-prone, lesion bypass DNA polymerase V (UmuC) conserved
Pf1N1B4_1565 -1.6 -3.7 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_4612 -1.6 -2.6 FIG00954117: hypothetical protein compare
Pf1N1B4_888 -1.6 -4.3 Transglycosylase, Slt family compare
Pf1N1B4_4051 -1.6 -4.3 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf1N1B4_2085 -1.6 -3.5 Uncharacterized protein similar to VCA0109 compare
Pf1N1B4_2526 -1.6 -11.5 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf1N1B4_958 -1.6 -2.3 Stringent starvation protein B compare
Pf1N1B4_2412 -1.6 -3.4 ATP-dependent 23S rRNA helicase DbpA compare
Pf1N1B4_4305 -1.5 -3.1 PUTATIVE METHYLTRANSFERASE compare
Pf1N1B4_2917 -1.5 -7.2 FIG140336: TPR domain protein compare
Pf1N1B4_3011 -1.5 -2.2 Tyrosine recombinase XerD compare
Pf1N1B4_1008 -1.5 -1.6 FIG006045: Sigma factor, ECF subfamily compare
Pf1N1B4_886 -1.5 -2.4 FIG137478: Hypothetical protein compare
Pf1N1B4_1492 -1.4 -1.5 FIG00959437: hypothetical protein compare
Pf1N1B4_3752 -1.4 -9.3 Aspartyl aminopeptidase conserved
Pf1N1B4_2106 -1.4 -3.2 Hydrogen peroxide-inducible genes activator compare
Pf1N1B4_3111 -1.4 -2.0 tRNA pseudouridine 13 synthase (EC 4.2.1.-) compare
Pf1N1B4_3492 -1.4 -3.4 DNA-3-methyladenine glycosylase (EC 3.2.2.20) compare
Pf1N1B4_959 -1.4 -9.3 Stringent starvation protein A compare
Pf1N1B4_1625 -1.4 -3.9 FIG00956267: hypothetical protein compare
Pf1N1B4_3591 -1.4 -5.9 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.41) compare
Pf1N1B4_1695 -1.4 -1.9 Cystine ABC transporter, ATP-binding protein compare
Pf1N1B4_1 -1.4 -2.0 Colicin V production protein compare
Pf1N1B4_2004 -1.4 -1.8 putative membrane protein compare
Pf1N1B4_644 -1.4 -2.0 Cold shock protein CspC compare
Pf1N1B4_6039 -1.3 -5.1 Endonuclease I precursor (EC 3.1.21.1) conserved
Pf1N1B4_5797 -1.3 -2.9 1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase (EC 1.3.1.25) compare
Pf1N1B4_5507 -1.3 -2.3 hypothetical protein compare
Pf1N1B4_1619 -1.3 -7.1 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf1N1B4_683 -1.3 -2.8 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_652 -1.3 -7.4 Sensory box histidine kinase compare
Pf1N1B4_4568 -1.3 -1.1 FIG00793915: hypothetical protein compare
Pf1N1B4_2253 -1.3 -4.3 Transcriptional regulator, TetR family compare
Pf1N1B4_1194 -1.3 -2.1 hypothetical protein compare
Pf1N1B4_1105 -1.3 -2.4 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf1N1B4_3547 -1.3 -1.9 DNA-binding response regulator compare
Pf1N1B4_4038 -1.3 -2.5 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
Pf1N1B4_3991 -1.3 -1.9 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf1N1B4_724 -1.3 -3.0 DNA-binding response regulator ColR compare
Pf1N1B4_2878 -1.3 -6.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf1N1B4_5833 -1.3 -2.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) compare
Pf1N1B4_544 -1.3 -2.2 Small-conductance mechanosensitive channel compare
Pf1N1B4_4030 -1.2 -2.7 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
Pf1N1B4_2706 -1.2 -2.6 FIG00954871: hypothetical protein compare
Pf1N1B4_5105 -1.2 -2.7 Peptide ABC transporter, ATP-binding protein compare
Pf1N1B4_1307 -1.2 -1.8 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_4505 -1.2 -3.0 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_3552 -1.2 -3.3 Hypothetical YciO protein, TsaC/YrdC paralog compare
Pf1N1B4_912 -1.2 -3.8 Toxin mRNA interferase YgiU compare
Pf1N1B4_345 -1.2 -1.4 Integration host factor beta subunit compare
Pf1N1B4_275 -1.2 -1.6 Organic hydroperoxide resistance transcriptional regulator compare
Pf1N1B4_21 -1.2 -3.0 Probable hydrolase compare
Pf1N1B4_2377 -1.2 -5.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_1116 -1.2 -7.4 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf1N1B4_3799 -1.2 -2.9 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) compare
Pf1N1B4_5133 -1.2 -2.9 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) compare
Pf1N1B4_2935 -1.2 -2.1 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf1N1B4_2879 -1.1 -5.1 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf1N1B4_3491 -1.1 -2.6 tRNA(Cytosine32)-2-thiocytidine synthetase compare
Pf1N1B4_6038 -1.1 -2.0 FIG00953874: hypothetical protein compare
Pf1N1B4_4486 -1.1 -1.9 Outer membrane protein (porin) compare
Pf1N1B4_2887 -1.1 -5.4 Chromosome segregation ATPases compare
Pf1N1B4_3855 -1.1 -2.8 Chromosome partition protein smc compare
Pf1N1B4_4993 -1.1 -3.3 Arabinose efflux permease compare
Pf1N1B4_691 -1.1 -2.1 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf1N1B4_4041 -1.1 -2.0 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
Pf1N1B4_1252 -1.1 -3.4 Adenosine deaminase (EC 3.5.4.4) compare
Pf1N1B4_1914 -1.1 -4.2 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf1N1B4_2736 -1.1 -2.6 ATP-dependent RNA helicase PA3950 compare
Pf1N1B4_1936 -1.1 -4.4 Chromosome (plasmid) partitioning protein ParA compare
Pf1N1B4_2712 -1.1 -3.5 tRNA-i(6)A37 methylthiotransferase compare
Pf1N1B4_901 -1.1 -2.7 hypothetical protein compare
Pf1N1B4_2891 -1.1 -2.0 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf1N1B4_4553 -1.1 -2.9 FIG00959354: hypothetical protein compare
Pf1N1B4_5219 -1.1 -2.0 tRNA-Gly-CCC compare
Pf1N1B4_3782 -1.1 -1.9 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) compare
Pf1N1B4_1845 -1.1 -2.5 FIG00954395: hypothetical protein compare
Pf1N1B4_2807 -1.0 -1.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf1N1B4_5013 -1.0 -1.9 Cointegrate resolution protein T compare
Pf1N1B4_765 -1.0 -1.8 Cys-tRNA(Pro) deacylase YbaK compare
Pf1N1B4_4571 -1.0 -2.2 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf1N1B4_103 -1.0 -3.6 Histidine permease YuiF compare
Pf1N1B4_1115 -1.0 -6.3 Dna binding response regulator PrrA (RegA) compare
Pf1N1B4_3833 -1.0 -5.2 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_3362 -1.0 -2.9 Multidrug resistance protein B compare
Pf1N1B4_5279 -1.0 -2.1 hypothetical protein compare
Pf1N1B4_1069 -1.0 -3.8 YrbA protein compare
Pf1N1B4_3448 -1.0 -2.7 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.78) compare
Pf1N1B4_4446 -1.0 -1.8 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_259 -1.0 -2.0 Glutathione peroxidase family protein compare
Pf1N1B4_3456 -1.0 -3.4 ATP-binding protein PhnN; Guanylate kinase (EC 2.7.4.8) compare
Pf1N1B4_1750 -1.0 -2.2 Death on curing protein, Doc toxin compare
Pf1N1B4_2552 -1.0 -2.5 OsmC/Ohr family protein compare
Pf1N1B4_3750 -1.0 -2.6 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel compare
Pf1N1B4_2026 -1.0 -2.3 Transcriptional regulator compare
Pf1N1B4_2912 -1.0 -1.6 GTP-binding and nucleic acid-binding protein YchF compare
Pf1N1B4_3074 -1.0 -1.8 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf1N1B4_1661 -1.0 -3.5 Agmatine deiminase (EC 3.5.3.12) compare
Pf1N1B4_4474 -1.0 -1.9 transcription regulator protein compare
Pf1N1B4_193 -1.0 -3.1 Transporter, LysE family compare
Pf1N1B4_2189 -1.0 -2.4 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_668 -1.0 -4.2 Exodeoxyribonuclease I (EC 3.1.11.1) compare
Pf1N1B4_2527 -1.0 -5.9 ApaG protein compare
Pf1N1B4_2889 -1.0 -3.2 FIG00954491: hypothetical protein compare
Pf1N1B4_5949 -1.0 -1.1 Phosphomannomutase (EC 5.4.2.8) compare
Pf1N1B4_3347 -1.0 -4.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_4460 -1.0 -1.9 Cytochrome b561 compare
Pf1N1B4_5312 -1.0 -3.1 Putative activity regulator of membrane protease YbbK compare
Pf1N1B4_3486 -0.9 -3.2 Transcriptional regulator, AraC family compare
Pf1N1B4_4671 -0.9 -1.9 Short-chain dehydrogenase/reductase SDR compare
Pf1N1B4_4212 -0.9 -1.6 Gfa-like protein compare
Pf1N1B4_1892 -0.9 -2.7 ABC transporter ATP-binding protein USSDB6B compare
Pf1N1B4_4358 -0.9 -1.0 Acetyltransferase, GNAT family compare
Pf1N1B4_5059 -0.9 -1.1 Transcriptional regulator, LysR family compare
Pf1N1B4_1236 -0.9 -4.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_2035 -0.9 -3.2 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf1N1B4_4396 -0.9 -2.3 Arginine/ornithine ABC transporter, ATP-binding protein AotP compare
Pf1N1B4_3700 -0.9 -2.3 Putative permease often clustered with de novo purine synthesis compare
Pf1N1B4_3686 -0.9 -4.2 Branched-chain amino acid transport system carrier protein compare
Pf1N1B4_1617 -0.9 -4.3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_1005 -0.9 -2.0 probable membrane protein YPO0899 compare
Pf1N1B4_63 -0.9 -1.5 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
Pf1N1B4_1246 -0.9 -1.4 FIG00954047: hypothetical protein compare
Pf1N1B4_3508 -0.9 -2.9 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf1N1B4_4992 -0.9 -2.6 Dienelactone hydrolase and related enzymes compare
Pf1N1B4_2686 -0.9 -3.4 DedA protein compare
Pf1N1B4_2491 -0.9 -2.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_5675 -0.9 -2.1 hypothetical protein compare
Pf1N1B4_761 -0.9 -2.3 FIG00954879: hypothetical protein compare
Pf1N1B4_1178 -0.9 -3.4 DNA repair protein RecN compare
Pf1N1B4_4667 -0.9 -1.9 Acriflavin resistance plasma membrane protein compare
Pf1N1B4_2356 -0.9 -2.2 hypothetical protein compare
Pf1N1B4_1749 -0.9 -1.4 Prevent host death protein, Phd antitoxin compare
Pf1N1B4_4235 -0.9 -2.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf1N1B4_2037 -0.9 -2.2 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf1N1B4_5330 -0.9 -1.6 hypothetical protein compare
Pf1N1B4_1781 -0.9 -1.4 hypothetical protein compare
Pf1N1B4_2612 -0.9 -2.2 Putative transport protein compare
Pf1N1B4_3405 -0.9 -2.2 Signal transduction histidine kinase compare
Pf1N1B4_3403 -0.9 -2.4 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_5334 -0.9 -1.7 hypothetical protein compare
Pf1N1B4_2282 -0.9 -4.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_3713 -0.9 -1.6 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Pf1N1B4_751 -0.9 -1.2 hypothetical protein compare
Pf1N1B4_5512 -0.9 -1.1 hypothetical protein compare
Pf1N1B4_2486 -0.9 -1.5 hypothetical protein compare
Pf1N1B4_4532 -0.9 -2.0 ClpB protein compare
Pf1N1B4_367 -0.9 -2.8 Fumarate hydratase class II (EC 4.2.1.2) compare
Pf1N1B4_5061 -0.9 -2.7 Valyl-tRNA synthetase compare
Pf1N1B4_2021 -0.9 -1.5 hypothetical protein compare
Pf1N1B4_5906 -0.8 -1.6 Esterase/lipase compare
Pf1N1B4_4669 -0.8 -1.2 Heavy metal RND efflux outer membrane protein, CzcC family compare
Pf1N1B4_974 -0.8 -2.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_2517 -0.8 -2.8 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY compare
Pf1N1B4_1389 -0.8 -1.9 Lysine decarboxylase family compare
Pf1N1B4_2237 -0.8 -2.4 Ribonucleotide reductase, alpha subunit compare


Specific Phenotypes

For 13 genes in this experiment

For stress Cisplatin in Pseudomonas fluorescens FW300-N1B4

For stress Cisplatin across organisms