Experiment set2IT039 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with Cisplatin 0.006 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Pf1N1B4_5611 +2.4 4.9 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) compare
Pf1N1B4_2169 +2.3 5.5 FIG00953808: hypothetical protein compare
Pf1N1B4_904 +2.2 5.1 DNA-binding protein HU-beta compare
Pf1N1B4_1457 +2.2 13.3 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_1456 +2.1 11.1 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf1N1B4_337 +2.1 10.5 O-antigen export system permease protein RfbD compare
Pf1N1B4_1463 +2.1 14.4 hypothetical protein compare
Pf1N1B4_292 +2.1 19.1 ErfK/YbiS/YcfS/YnhG family protein compare
Pf1N1B4_291 +2.0 8.7 Major outer membrane lipoprotein I compare
Pf1N1B4_5924 +2.0 12.9 hypothetical protein compare
Pf1N1B4_336 +2.0 16.0 Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) compare
Pf1N1B4_1458 +1.9 11.2 Probable transcription regulator Mig-14 compare
Pf1N1B4_2117 +1.8 14.2 Ribonuclease PH (EC 2.7.7.56) compare
Pf1N1B4_290 +1.8 15.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2168 +1.8 7.6 FIG004064: hypothetical protein compare
Pf1N1B4_1472 +1.7 2.6 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
Pf1N1B4_3692 +1.7 3.8 Chaperone protein HtpG compare
Pf1N1B4_1469 +1.7 13.7 Heptose kinase WapQ, eukaryotic type compare
Pf1N1B4_3815 +1.7 5.7 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf1N1B4_3549 +1.6 3.1 YciL protein compare
Pf1N1B4_1370 +1.5 2.7 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf1N1B4_3909 +1.5 2.4 Cell division inhibitor-related protein compare
Pf1N1B4_3911 +1.5 6.1 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf1N1B4_3906 +1.5 4.0 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_5972 +1.5 2.6 Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1) compare
Pf1N1B4_284 +1.5 11.0 Universal stress protein family compare
Pf1N1B4_1668 +1.5 7.1 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf1N1B4_3224 +1.5 6.4 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
Pf1N1B4_2694 +1.5 9.7 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf1N1B4_287 +1.5 9.1 Possible periplasmic thiredoxin compare
Pf1N1B4_4024 +1.5 3.1 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_4830 +1.4 2.3 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_3454 +1.4 4.8 Mg/Co/Ni transporter MgtE / CBS domain compare
Pf1N1B4_3830 +1.4 3.0 CrfX protein compare
Pf1N1B4_1465 +1.4 10.9 Carbamoyltransferase in large core OS assembly cluster compare
Pf1N1B4_293 +1.4 8.0 hypothetical protein compare
Pf1N1B4_4337 +1.4 2.7 Transcriptional regulator compare
Pf1N1B4_4699 +1.4 1.9 Multidrug translocase MdfA compare
Pf1N1B4_909 +1.4 2.9 Ketosteroid isomerase-related protein compare
Pf1N1B4_2701 +1.4 12.5 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf1N1B4_5568 +1.4 3.4 hypothetical protein compare
Pf1N1B4_5311 +1.4 1.3 hypothetical protein compare
Pf1N1B4_296 +1.4 2.8 ABC transporter ATP-binding protein YvcR compare
Pf1N1B4_288 +1.4 7.7 FIG00958794: hypothetical protein compare
Pf1N1B4_4470 +1.3 3.2 Cobalt-zinc-cadmium resistance protein CzcD compare
Pf1N1B4_1466 +1.3 4.2 hypothetical protein compare
Pf1N1B4_441 +1.3 2.1 hypothetical protein compare
Pf1N1B4_289 +1.3 10.0 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf1N1B4_4422 +1.3 2.2 ABC transporter amino acid-binding protein compare
Pf1N1B4_6041 +1.3 2.9 Carbon storage regulator compare
Pf1N1B4_3510 +1.3 4.4 nucleoprotein/polynucleotide-associated enzyme compare
Pf1N1B4_3078 +1.3 2.1 FIG138056: a glutathione-dependent thiol reductase compare
Pf1N1B4_733 +1.2 1.3 Methionyl-tRNA synthetase (EC 6.1.1.10) compare
Pf1N1B4_1554 +1.2 7.0 predicted FeS cluster maintenance protein (from data) compare
Pf1N1B4_4296 +1.2 3.6 Histidine transporter, periplasmic histidine-binding protein compare
Pf1N1B4_539 +1.2 2.2 Transcriptional regulators compare
Pf1N1B4_4132 +1.2 2.3 Mobile element protein compare
Pf1N1B4_2713 +1.2 3.4 FIG00955339: hypothetical protein compare
Pf1N1B4_3113 +1.2 8.9 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf1N1B4_4462 +1.2 2.0 LysR family transcriptional regulator YbhD compare
Pf1N1B4_4731 +1.2 2.7 Sigma-54 dependent transcriptional regulator compare
Pf1N1B4_5926 +1.2 7.7 hypothetical protein compare
Pf1N1B4_2958 +1.2 2.2 Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-) compare
Pf1N1B4_197 +1.2 1.1 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_230 +1.2 2.4 FIG00953472: hypothetical protein compare
Pf1N1B4_2228 +1.2 3.8 FIG001590: Putative conserved exported protein precursor compare
Pf1N1B4_5393 +1.2 2.6 hypothetical protein compare
Pf1N1B4_338 +1.2 2.3 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_5500 +1.2 5.5 hypothetical protein compare
Pf1N1B4_1584 +1.1 1.6 Histidine ABC transporter, permease protein (TC 3.A.1) compare
Pf1N1B4_5927 +1.1 9.9 Capsular polysaccharide biosynthesis protein compare
Pf1N1B4_1461 +1.1 3.3 Protein fixF compare
Pf1N1B4_4975 +1.1 3.6 hypothetical protein compare
Pf1N1B4_3582 +1.1 2.3 C-methyltransferase compare
Pf1N1B4_340 +1.1 4.9 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_4219 +1.1 2.0 FIG01074225: hypothetical protein compare
Pf1N1B4_5275 +1.1 2.2 hypothetical protein compare
Pf1N1B4_1135 +1.1 2.3 FIG00960055: hypothetical protein compare
Pf1N1B4_3229 +1.1 5.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_4980 +1.1 1.4 putative lipoprotein compare
Pf1N1B4_5745 +1.1 1.6 FIG139928: Putative protease compare
Pf1N1B4_3129 +1.1 1.5 Prophage baseplate assembly protein V compare
Pf1N1B4_4433 +1.1 2.6 FIG035246: DoxX family protein compare
Pf1N1B4_3816 +1.1 5.9 FIG139976: hypothetical protein compare
Pf1N1B4_5838 +1.1 1.6 FIG00956589: hypothetical protein compare
Pf1N1B4_5242 +1.1 1.6 hypothetical protein compare
Pf1N1B4_3927 +1.1 1.4 hypothetical protein compare
Pf1N1B4_3458 +1.1 1.9 hypothetical protein compare
Pf1N1B4_3525 +1.1 1.9 hydrolase, alpha/beta fold family compare
Pf1N1B4_295 +1.1 6.6 Arylesterase precursor (EC 3.1.1.2) compare
Pf1N1B4_286 +1.1 7.5 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf1N1B4_611 +1.1 2.4 CoA transferase, CAIB/BAIF family compare
Pf1N1B4_2695 +1.1 2.0 Rare lipoprotein A precursor compare
Pf1N1B4_561 +1.0 2.7 Glutathione S-transferase (EC 2.5.1.18) compare
Pf1N1B4_2209 +1.0 6.6 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_2731 +1.0 3.1 Uncharacterized protein conserved in bacteria compare
Pf1N1B4_1460 +1.0 7.1 Lipid A core - O-antigen ligase and related enzymes compare
Pf1N1B4_3501 +1.0 4.3 BarA sensory histidine kinase (= VarS = GacS) compare
Pf1N1B4_1527 +1.0 2.8 Queuosine Biosynthesis QueC ATPase compare
Pf1N1B4_1417 +1.0 6.5 NAD(P)HX epimerase / NAD(P)HX dehydratase compare
Pf1N1B4_2417 +1.0 3.3 Betaine aldehyde dehydrogenase (EC 1.2.1.8) compare
Pf1N1B4_5930 +1.0 4.1 Exopolysaccharide production protein ExoZ compare
Pf1N1B4_3915 +1.0 5.2 FIG00954981: hypothetical protein compare
Pf1N1B4_4336 +1.0 2.4 FMN-dependent NADH-azoreductase compare
Pf1N1B4_2622 +1.0 3.5 FIG006163: hypothetical protein compare
Pf1N1B4_1586 +1.0 6.7 Purine-cytosine permease compare
Pf1N1B4_2615 +1.0 4.0 Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1 compare
Pf1N1B4_526 +1.0 2.9 Undecaprenyl pyrophosphate synthase compare
Pf1N1B4_5386 +1.0 2.6 hypothetical protein compare
Pf1N1B4_3494 +1.0 2.2 Flavoprotein WrbA compare
Pf1N1B4_5925 +1.0 5.6 hypothetical protein compare
Pf1N1B4_4870 +1.0 1.1 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf1N1B4_2380 +1.0 7.5 Cytochrome B561 compare
Pf1N1B4_3531 +0.9 2.5 FIG039061: hypothetical protein related to heme utilization compare
Pf1N1B4_3997 +0.9 2.9 Uncharacterized protein YtfM precursor compare
Pf1N1B4_2111 +0.9 6.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_5239 +0.9 2.2 hypothetical protein compare
Pf1N1B4_4289 +0.9 3.6 Methyl-accepting chemotaxis protein compare
Pf1N1B4_5917 +0.9 1.5 Multimeric flavodoxin WrbA compare
Pf1N1B4_2381 +0.9 6.6 Protein yceI precursor compare
Pf1N1B4_1441 +0.9 6.9 Putative esterase, FIGfam005057 compare
Pf1N1B4_4826 +0.9 1.3 glutamine synthetase family protein compare
Pf1N1B4_1838 +0.9 2.1 FIG00955509: hypothetical protein compare
Pf1N1B4_1468 +0.9 7.3 InaA protein compare
Pf1N1B4_3829 +0.9 6.8 Magnesium and cobalt transport protein CorA compare
Pf1N1B4_3328 +0.9 1.8 Rhodanese-like domain protein compare
Pf1N1B4_2224 +0.9 1.6 FIG00953390: hypothetical protein compare
Pf1N1B4_3345 +0.9 5.4 Ribonuclease D (EC 3.1.26.3) compare
Pf1N1B4_1418 +0.9 6.9 Epoxyqueuosine (oQ) reductase QueG compare
Pf1N1B4_5719 +0.9 2.5 hypothetical protein compare
Pf1N1B4_1630 +0.9 2.7 A/G-specific adenine glycosylase (EC 3.2.2.-) compare
Pf1N1B4_885 +0.9 2.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_2668 +0.9 6.6 DedA protein compare
Pf1N1B4_3030 +0.9 2.9 Transcriptional regulators, LysR family compare
Pf1N1B4_1535 +0.9 2.4 hypothetical protein compare
Pf1N1B4_2401 +0.9 2.0 Lipoprotein, putative compare
Pf1N1B4_115 +0.9 1.4 Membrane protein mosC compare
Pf1N1B4_5817 +0.9 2.1 Decarboxylase family protein compare
Pf1N1B4_2640 +0.9 3.0 FIG003461: hypothetical protein compare
Pf1N1B4_3828 +0.9 5.3 Ribonuclease E inhibitor RraA compare
Pf1N1B4_4459 +0.9 1.5 Thermostable hemolysin delta-VPH compare
Pf1N1B4_1675 +0.9 2.2 Transcriptional regulator compare
Pf1N1B4_1558 +0.9 2.1 Transcriptional regulator PhaD compare
Pf1N1B4_5864 +0.9 1.7 Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF compare
Pf1N1B4_309 +0.9 2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_5640 +0.9 2.5 Transcriptional regulator, IclR family compare
Pf1N1B4_4716 +0.9 1.7 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) compare
Pf1N1B4_1311 +0.9 3.7 Probable transmembrane protein compare
Pf1N1B4_2193 +0.9 2.6 hypothetical protein compare
Pf1N1B4_4982 +0.9 1.8 Transcriptional regulator, AraC family compare
Pf1N1B4_267 +0.9 1.0 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf1N1B4_219 +0.8 2.5 Acyclic terpenes utilization regulator AtuR, TetR family compare
Pf1N1B4_5265 +0.8 2.9 hypothetical protein compare
Pf1N1B4_285 +0.8 5.2 5'-nucleotidase (EC 3.1.3.5) compare
Pf1N1B4_4293 +0.8 2.1 hypothetical protein compare
Pf1N1B4_1464 +0.8 5.1 Glycosyl transferase compare
Pf1N1B4_4273 +0.8 2.7 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf1N1B4_3976 +0.8 3.7 Transmembrane regulator protein PrtR compare
Pf1N1B4_4725 +0.8 1.7 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) compare
Pf1N1B4_438 +0.8 2.5 hypothetical protein compare
Pf1N1B4_3352 +0.8 2.3 tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34) compare
Pf1N1B4_2359 +0.8 2.0 Chemotaxis signal transduction protein compare
Pf1N1B4_5711 +0.8 2.2 Salicylate hydroxylase (EC 1.14.13.1) compare
Pf1N1B4_5077 +0.8 1.5 D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) compare
Pf1N1B4_4729 +0.8 1.4 Hemolysin-type calcium-binding region compare
Pf1N1B4_2003 +0.8 3.2 FIG00956226: hypothetical protein compare
Pf1N1B4_4255 +0.8 2.1 Putative phosphatase YfbT compare
Pf1N1B4_1096 +0.8 2.9 Septum formation protein Maf compare
Pf1N1B4_2060 +0.8 2.0 hypothetical protein compare
Pf1N1B4_3147 +0.8 3.9 Putative NADPH-quinone reductase (modulator of drug activity B) compare
Pf1N1B4_4282 +0.8 2.4 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf1N1B4_4168 +0.8 1.3 putative membrane protein compare
Pf1N1B4_3613 +0.8 1.6 hypothetical protein compare
Pf1N1B4_2485 +0.8 1.6 Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy compare
Pf1N1B4_2433 +0.8 2.1 FIG00953108: hypothetical protein compare
Pf1N1B4_3112 +0.8 2.8 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_4455 +0.8 1.3 FIG00953528: hypothetical protein compare
Pf1N1B4_3817 +0.8 2.5 FIG008443: hypothetical protein compare
Pf1N1B4_232 +0.8 1.3 DNA-binding response regulator, LuxR family compare
Pf1N1B4_3117 +0.8 5.0 DNA mismatch repair protein MutS compare
Pf1N1B4_43 +0.8 3.7 hypothetical protein compare
Pf1N1B4_2860 +0.8 4.3 FIG00954153: hypothetical protein compare
Pf1N1B4_447 +0.8 6.8 FIG004453: protein YceG like compare
Pf1N1B4_4741 +0.8 2.1 Undecaprenyl-diphosphatase (EC 3.6.1.27) compare
Pf1N1B4_1775 +0.8 4.2 hypothetical protein compare
Pf1N1B4_5282 +0.8 2.4 Phage protein compare
Pf1N1B4_2858 +0.8 5.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf1N1B4_3744 +0.8 2.5 ABC transporter, ATP-binding protein compare
Pf1N1B4_5006 +0.8 2.8 Rtn protein compare
Pf1N1B4_5090 +0.8 1.8 glycosyl transferase, family 2 compare
Pf1N1B4_78 +0.8 2.4 FIG00956937: hypothetical protein compare
Pf1N1B4_5886 +0.8 1.9 Undecaprenyl-phosphate galactosephosphotransferase (EC 2.7.8.6) compare
Pf1N1B4_4751 +0.8 1.9 Ku domain protein compare
Pf1N1B4_380 +0.8 3.2 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf1N1B4_716 +0.8 2.2 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites compare
Pf1N1B4_4698 +0.8 2.4 rfbN protein compare
Pf1N1B4_5567 +0.8 2.7 transcriptional regulator MvaT, P16 subunit, putative compare
Pf1N1B4_5294 +0.8 1.4 hypothetical protein compare
Pf1N1B4_1590 +0.8 3.9 Histidine utilization repressor compare
Pf1N1B4_855 +0.8 1.6 FIG021952: putative membrane protein compare


Specific Phenotypes

For 13 genes in this experiment

For stress Cisplatin in Pseudomonas fluorescens FW300-N1B4

For stress Cisplatin across organisms