Experiment set2IT039 for Methanococcus maripaludis S2

Compare to:

Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 & Casamino Acid FREE

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS07815 +4.0 11.4 DUF2120 domain-containing protein compare
MMP_RS06485 +3.7 8.7 zinc ribbon domain-containing protein compare
MMP_RS02550 +2.8 9.1 helix-turn-helix transcriptional regulator compare
MMP_RS01370 +2.5 19.3 acetate--CoA ligase family protein compare
MMP_RS06870 +2.4 12.2 DedA family protein compare
MMP_RS06905 +1.6 1.6 hypothetical protein compare
MMP_RS08340 +1.4 8.2 4Fe-4S binding protein compare
MMP_RS08350 +1.3 2.0 hypothetical protein compare
MMP_RS01495 +1.3 11.3 TraB/GumN family protein compare
MMP_RS07095 +1.3 1.8 PspC domain-containing protein compare
MMP_RS08365 +1.2 5.1 energy conserving hydrogenase EhbF compare
MMP_RS00625 +1.2 2.3 hypothetical protein compare
MMP_RS08345 +1.2 9.2 4Fe-4S binding protein compare
MMP_RS02245 +1.1 5.4 hypothetical protein compare
MMP_RS08360 +1.1 6.4 hypothetical protein compare
MMP_RS08355 +1.1 6.3 Na(+)/H(+) antiporter subunit B compare
MMP_RS05950 +1.1 7.0 nickel-dependent hydrogenase large subunit compare
MMP_RS08370 +1.0 1.1 cation:proton antiporter subunit C compare
MMP_RS08845 +1.0 8.6 archaellum operon transcriptional activator EarA family protein compare
MMP_RS03875 +1.0 1.5 hypothetical protein compare
MMP_RS01775 +1.0 3.5 TIGR00297 family protein compare
MMP_RS01240 +1.0 0.8 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS08850 +1.0 8.0 hypothetical protein compare
MMP_RS02645 +0.9 1.9 ArsR family transcriptional regulator compare
MMP_RS07725 +0.9 4.6 4Fe-4S dicluster domain-containing protein compare
MMP_RS06900 +0.9 1.8 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS08335 +0.9 3.7 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS01765 +0.9 1.7 HIT family protein compare
MMP_RS06520 +0.9 1.8 DUF1786 domain-containing protein compare
MMP_RS04610 +0.9 0.9 Dabb family protein compare
MMP_RS03870 +0.8 1.6 purine NTPase compare
MMP_RS08380 +0.8 3.1 phosphatase PAP2 family protein compare
MMP_RS07685 +0.8 4.6 TIGR01212 family radical SAM protein compare
MMP_RS06610 +0.8 1.0 DUF2334 domain-containing protein compare
MMP_RS06545 +0.8 5.5 ferredoxin family protein compare
MMP_RS01645 +0.8 1.9 SWIM zinc finger family protein compare
MMP_RS08445 +0.7 2.2 DUF2099 family protein compare
MMP_RS08400 +0.7 0.6 MJ0307 family thioredoxin compare
MMP_RS05715 +0.7 1.5 hypothetical protein compare
MMP_RS06540 +0.7 2.5 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS00520 +0.7 1.2 RNA polymerase Rpb4 family protein compare
MMP_RS08405 +0.6 1.9 MFS transporter compare
MMP_RS06185 +0.6 1.8 thermonuclease family protein compare
MMP_RS00125 +0.6 1.4 DUF2798 domain-containing protein compare
MMP_RS01335 +0.6 1.8 prefoldin subunit beta compare
MMP_RS04410 +0.6 0.8 hypothetical protein compare
MMP_RS03215 +0.6 4.0 MBL fold metallo-hydrolase compare
MMP_RS00565 +0.6 1.4 CBS domain-containing protein compare
MMP_RS08215 +0.6 2.0 DUF483 domain-containing protein compare
MMP_RS00990 +0.6 2.8 hypothetical protein compare
MMP_RS05435 +0.6 2.4 5'/3'-nucleotidase SurE compare
MMP_RS01660 +0.6 0.7 hypothetical protein compare
MMP_RS01850 +0.6 1.9 phosphate ABC transporter substrate-binding protein compare
MMP_RS07130 +0.6 1.6 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS06550 +0.6 4.0 AMP-binding protein compare
MMP_RS06365 +0.6 1.9 hypothetical protein compare
MMP_RS08835 +0.6 1.5 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS06990 +0.5 2.2 CatB-related O-acetyltransferase compare
MMP_RS00345 +0.5 3.7 DUF2666 domain-containing protein compare
MMP_RS05315 +0.5 1.1 hypothetical protein compare
MMP_RS07765 +0.5 1.4 sodium:alanine symporter family protein compare
MMP_RS08290 +0.5 4.3 DNA-binding protein Alba compare
MMP_RS01675 +0.5 1.2 hypothetical protein compare
MMP_RS05955 +0.5 1.6 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS00540 +0.5 1.4 PLP-dependent aminotransferase family protein compare
MMP_RS00675 +0.5 0.6 nitroreductase family protein compare
MMP_RS02810 +0.5 2.0 hypothetical protein compare
MMP_RS07905 +0.5 0.9 DUF3343 domain-containing protein compare
MMP_RS02745 +0.5 1.7 hypothetical protein compare
MMP_RS05365 +0.5 1.2 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS02985 +0.5 1.4 hypothetical protein compare
MMP_RS05660 +0.5 1.2 phosphate ABC transporter substrate-binding protein compare
MMP_RS00150 +0.5 1.3 AAA family ATPase compare
MMP_RS01525 +0.5 1.3 nucleoside-diphosphate kinase compare
MMP_RS05830 +0.5 0.6 peptidyl-prolyl cis-trans isomerase compare
MMP_RS08235 +0.5 2.9 hypothetical protein compare
MMP_RS08535 +0.5 3.1 bis-aminopropyl spermidine synthase family protein compare
MMP_RS07890 +0.5 1.6 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS05295 +0.5 2.3 minichromosome maintenance protein MCM compare
MMP_RS07355 +0.5 0.7 transcription factor S compare
MMP_RS00080 +0.5 2.8 RecB-family nuclease compare
MMP_RS04445 +0.5 1.3 P-II family nitrogen regulator compare
MMP_RS06575 +0.5 2.4 fluoride efflux transporter CrcB compare
MMP_RS06190 +0.4 0.9 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS03520 +0.4 1.4 YwbE family protein compare
MMP_RS08775 +0.4 1.9 methanogenesis marker 9 domain-containing protein compare
MMP_RS00880 +0.4 2.1 ribosome assembly RNA-binding protein YhbY compare
MMP_RS08750 +0.4 1.4 hypothetical protein compare
MMP_RS08555 +0.4 1.9 hypothetical protein compare
MMP_RS08685 +0.4 2.1 hypothetical protein compare
MMP_RS02605 +0.4 0.5 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS05970 +0.4 1.8 class II SORL domain-containing protein compare
MMP_RS07125 +0.4 1.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02590 +0.4 1.1 low molecular weight phosphatase family protein compare
MMP_RS07680 +0.4 1.9 DUF366 family protein compare
MMP_RS02790 +0.4 0.7 class III signal peptide-containing protein compare
MMP_RS08660 +0.4 2.0 DHH family phosphoesterase compare
MMP_RS02025 +0.4 1.8 DNA-directed DNA polymerase compare
MMP_RS02805 +0.4 0.7 HEPN domain-containing protein compare
MMP_RS02990 +0.4 1.8 AMP-binding protein compare
MMP_RS08085 +0.4 2.8 hypothetical protein compare
MMP_RS04460 +0.4 1.7 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS02595 +0.4 0.7 putative zinc-binding protein compare
MMP_RS06080 +0.4 1.5 radical SAM protein compare
MMP_RS02320 +0.4 1.2 glutamate-cysteine ligase family protein compare
MMP_RS06150 +0.4 1.2 hypothetical protein compare
MMP_RS08705 +0.4 2.7 sulfopyruvate decarboxylase subunit beta compare
MMP_RS00810 +0.4 1.5 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06515 +0.4 1.3 UPF0489 family protein compare
MMP_RS01540 +0.4 1.4 DUF504 domain-containing protein compare
MMP_RS04055 +0.4 0.8 hypothetical protein compare
MMP_RS03150 +0.4 2.7 phosphoglycerate mutase compare
MMP_RS08205 +0.3 1.3 stage II sporulation protein M compare
MMP_RS05935 +0.3 2.0 uroporphyrinogen decarboxylase family protein compare
MMP_RS04175 +0.3 1.3 permease compare
MMP_RS08230 +0.3 2.4 50S ribosomal protein L11 methyltransferase compare
MMP_RS06290 +0.3 1.6 DNA repair and recombination protein RadA compare
MMP_RS04625 +0.3 2.1 DEAD/DEAH box helicase compare
MMP_RS06225 +0.3 1.0 DNA double-strand break repair nuclease NurA compare
MMP_RS01055 +0.3 1.8 hypothetical protein compare
MMP_RS07590 +0.3 2.7 hypothetical protein compare
MMP_RS01100 +0.3 0.6 ABC transporter ATP-binding protein compare
MMP_RS02895 +0.3 2.4 DHH family phosphoesterase compare
MMP_RS00660 +0.3 2.8 alkaline phosphatase family protein compare
MMP_RS04785 +0.3 2.3 hypothetical protein compare
MMP_RS05535 +0.3 1.1 hypothetical protein compare
MMP_RS05545 +0.3 2.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00280 +0.3 1.4 DUF2118 domain-containing protein compare
MMP_RS06910 +0.3 2.3 RlmF-related methyltransferase compare
MMP_RS07715 +0.3 2.2 YfcE family phosphodiesterase compare
MMP_RS03820 +0.3 1.7 EamA family transporter compare
MMP_RS06745 +0.3 1.4 DUF2119 domain-containing protein compare
MMP_RS05700 +0.3 2.4 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS00195 +0.3 2.6 DUF4013 domain-containing protein compare
MMP_RS08430 +0.3 2.2 HAD family hydrolase compare
MMP_RS08245 +0.3 0.9 DUF4013 domain-containing protein compare
MMP_RS08395 +0.3 1.4 DsrE family protein compare
MMP_RS03755 +0.3 2.3 MarR family transcriptional regulator compare
MMP_RS07835 +0.3 1.4 TldD/PmbA family protein compare
MMP_RS06860 +0.3 0.4 4Fe-4S binding protein compare
MMP_RS06590 +0.3 1.0 GNAT family N-acetyltransferase compare
MMP_RS05720 +0.3 1.7 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS08265 +0.3 1.4 rubrerythrin compare
MMP_RS08640 +0.3 2.2 TIM barrel protein compare
MMP_RS06280 +0.3 0.7 alpha-glucan family phosphorylase compare
MMP_RS08325 +0.3 2.3 hypothetical protein compare
MMP_RS07855 +0.3 1.1 class I SAM-dependent methyltransferase compare
MMP_RS08250 +0.3 1.4 pyruvate kinase compare
MMP_RS08830 +0.3 0.7 GTP-binding protein compare
MMP_RS08130 +0.3 1.3 IGHMBP2 family helicase compare
MMP_RS02300 +0.3 2.0 NAD(P)H-dependent oxidoreductase compare
MMP_RS06660 +0.3 0.9 glycosyltransferase family 4 protein compare
MMP_RS02975 +0.3 0.9 DUF2124 domain-containing protein compare
MMP_RS01415 +0.3 1.2 DUF2067 domain-containing protein compare
MMP_RS01465 +0.3 1.2 hypothetical protein compare
MMP_RS01120 +0.3 0.8 permease compare
MMP_RS08315 +0.3 0.9 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS02495 +0.3 1.0 hypothetical protein compare
MMP_RS06310 +0.3 0.7 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS03775 +0.3 1.0 4Fe-4S dicluster domain-containing protein compare
MMP_RS05225 +0.3 1.6 RluA family pseudouridine synthase compare
MMP_RS02640 +0.3 1.6 DUF6198 family protein compare
MMP_RS00335 +0.3 1.4 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS01990 +0.3 1.0 hypothetical protein compare
MMP_RS05355 +0.3 0.4 hypothetical protein compare
MMP_RS02965 +0.3 1.2 carboxymuconolactone decarboxylase family protein compare
MMP_RS07560 +0.3 1.3 prefoldin subunit alpha compare
MMP_RS04880 +0.3 1.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03860 +0.3 2.1 hypothetical protein compare
MMP_RS02575 +0.3 1.1 CAAX prenyl protease Rce1 compare
MMP_RS04510 +0.3 1.3 ABC transporter permease subunit compare
MMP_RS06200 +0.3 2.0 M24 family metallopeptidase compare
MMP_RS08990 +0.3 1.0 hypothetical protein compare
MMP_RS01155 +0.3 1.8 XRE family transcriptional regulator compare
MMP_RS02740 +0.3 1.3 hypothetical protein compare
MMP_RS00670 +0.3 1.1 TIM barrel protein compare
MMP_RS00850 +0.3 1.3 TIGR01177 family methyltransferase compare
MMP_RS05975 +0.3 0.5 hypothetical protein compare
MMP_RS06490 +0.2 1.3 hypothetical protein compare
MMP_RS05235 +0.2 1.3 exodeoxyribonuclease III compare
MMP_RS06975 +0.2 0.7 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS09035 +0.2 1.0 hypothetical protein compare
MMP_RS04190 +0.2 1.6 hypothetical protein compare
MMP_RS02230 +0.2 2.0 sodium-dependent transporter compare
MMP_RS08160 +0.2 1.5 EamA family transporter compare
MMP_RS06300 +0.2 1.3 ABC transporter substrate-binding protein compare
MMP_RS01570 +0.2 0.5 hypothetical protein compare
MMP_RS06525 +0.2 0.4 YciI family protein compare
MMP_RS01115 +0.2 2.0 molybdopterin molybdotransferase MoeA compare
MMP_RS01845 +0.2 1.4 hypothetical protein compare
MMP_RS00650 +0.2 1.3 ABC transporter ATP-binding protein compare
MMP_RS04495 +0.2 0.8 cation:proton antiporter compare
MMP_RS08625 +0.2 1.8 type II/IV secretion system ATPase subunit compare
MMP_RS08175 +0.2 1.6 7-cyano-7-deazaguanine synthase compare
MMP_RS08755 +0.2 2.0 sodium:solute symporter family protein compare
MMP_RS02565 +0.2 1.1 hypothetical protein compare
MMP_RS04505 +0.2 1.5 glycine betaine ABC transporter substrate-binding protein compare
MMP_RS03220 +0.2 0.8 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS00645 +0.2 1.6 iron ABC transporter permease compare
MMP_RS04100 +0.2 0.8 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For nutrient t2 Sodium acetate in Methanococcus maripaludis S2

For nutrient t2 Sodium acetate across organisms