Experiment set2IT038 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with Thallium(I) acetate 0.008 mg/ml

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_731 -3.1 -4.9 Scaffold protein for [4Fe-4S] cluster assembly ApbC, MRP-like compare
Pf1N1B4_1463 -2.9 -10.0 hypothetical protein compare
Pf1N1B4_1916 -2.9 -3.3 Chaperone protein YscY (Yop proteins translocation protein Y) compare
Pf1N1B4_1460 -2.8 -11.4 Lipid A core - O-antigen ligase and related enzymes compare
Pf1N1B4_2106 -2.8 -4.4 Hydrogen peroxide-inducible genes activator compare
Pf1N1B4_337 -2.7 -6.3 O-antigen export system permease protein RfbD compare
Pf1N1B4_1403 -2.7 -8.1 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_5659 -2.6 -12.8 NfuA Fe-S protein maturation compare
Pf1N1B4_1461 -2.6 -3.4 Protein fixF compare
Pf1N1B4_1554 -2.6 -8.3 predicted FeS cluster maintenance protein (from data) compare
Pf1N1B4_2386 -2.6 -5.9 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf1N1B4_2416 -2.3 -8.3 Choline dehydrogenase (EC 1.1.99.1) conserved
Pf1N1B4_336 -2.3 -14.8 Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) compare
Pf1N1B4_3143 -2.2 -3.2 RecA protein compare
Pf1N1B4_2668 -1.9 -10.3 DedA protein compare
Pf1N1B4_2764 -1.7 -4.5 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) conserved
Pf1N1B4_2105 -1.7 -3.0 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_769 -1.6 -7.3 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_1830 -1.6 -7.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_2874 -1.5 -2.5 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_2418 -1.5 -5.0 HTH-type transcriptional regulator BetI conserved
Pf1N1B4_644 -1.5 -2.4 Cold shock protein CspC compare
Pf1N1B4_3566 -1.5 -6.0 Phenylalanine-4-hydroxylase (EC 1.14.16.1) compare
Pf1N1B4_1475 -1.5 -5.0 FIG00962376: hypothetical protein compare
Pf1N1B4_2037 -1.5 -4.1 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf1N1B4_4028 -1.4 -4.3 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
Pf1N1B4_1632 -1.4 -4.0 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf1N1B4_2026 -1.4 -3.4 Transcriptional regulator compare
Pf1N1B4_3248 -1.4 -4.2 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf1N1B4_3906 -1.3 -3.9 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_1052 -1.3 -2.7 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
Pf1N1B4_412 -1.3 -2.3 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_5556 -1.3 -3.2 hypothetical protein compare
Pf1N1B4_2560 -1.2 -4.6 hypothetical protein compare
Pf1N1B4_4571 -1.2 -2.6 ADA regulatory protein / Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf1N1B4_1115 -1.2 -7.5 Dna binding response regulator PrrA (RegA) compare
Pf1N1B4_4518 -1.2 -3.3 Possible pyrimidine permease in reductive pathway compare
Pf1N1B4_3911 -1.2 -3.8 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf1N1B4_4366 -1.2 -2.6 hypothetical protein compare
Pf1N1B4_1492 -1.2 -1.6 FIG00959437: hypothetical protein compare
Pf1N1B4_6037 -1.2 -3.1 L-asparaginase (EC 3.5.1.1) compare
Pf1N1B4_3005 -1.2 -7.5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf1N1B4_69 -1.2 -2.5 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_4299 -1.2 -3.5 sensor histidine kinase compare
Pf1N1B4_2272 -1.2 -3.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf1N1B4_379 -1.2 -3.7 Protein of unknown function UPF0060 compare
Pf1N1B4_2417 -1.2 -2.7 Betaine aldehyde dehydrogenase (EC 1.2.1.8) compare
Pf1N1B4_2489 -1.1 -3.9 Biotin synthesis protein BioH compare
Pf1N1B4_3713 -1.1 -2.3 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
Pf1N1B4_141 -1.1 -5.6 PvdE, pyoverdine ABC export system, fused ATPase and permease components compare
Pf1N1B4_623 -1.1 -1.8 Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10) compare
Pf1N1B4_2465 -1.1 -1.5 Two-component response regulator CreB compare
Pf1N1B4_2552 -1.1 -3.1 OsmC/Ohr family protein compare
Pf1N1B4_3582 -1.1 -2.0 C-methyltransferase compare
Pf1N1B4_4029 -1.1 -2.4 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
Pf1N1B4_364 -1.1 -3.3 Rhodanese domain protein UPF0176 compare
Pf1N1B4_2085 -1.1 -3.0 Uncharacterized protein similar to VCA0109 compare
Pf1N1B4_1034 -1.1 -3.7 hypothetical protein compare
Pf1N1B4_1615 -1.1 -3.0 Glutaredoxin 3 (Grx3) compare
Pf1N1B4_3241 -1.1 -2.3 hypothetical protein compare
Pf1N1B4_1474 -1.1 -3.7 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf1N1B4_2005 -1.1 -2.1 ATP-dependent DNA helicase UvrD/PcrA compare
Pf1N1B4_4918 -1.1 -2.5 Predicted enzyme of the cupin superfamily compare
Pf1N1B4_3508 -1.1 -3.2 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf1N1B4_2550 -1.1 -3.6 Lipoate-protein ligase A compare
Pf1N1B4_1866 -1.0 -2.7 Methionine ABC transporter ATP-binding protein compare
Pf1N1B4_4505 -1.0 -2.2 Coenzyme PQQ synthesis protein E compare
Pf1N1B4_3751 -1.0 -0.8 FIG00953060: hypothetical protein compare
Pf1N1B4_5146 -1.0 -1.9 Chromosome initiation inhibitor compare
Pf1N1B4_365 -1.0 -3.8 Cell division protein BolA compare
Pf1N1B4_4055 -1.0 -5.5 ATP-dependent Clp protease ATP-binding subunit ClpA compare
Pf1N1B4_3486 -1.0 -2.5 Transcriptional regulator, AraC family compare
Pf1N1B4_4857 -1.0 -4.1 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf1N1B4_198 -1.0 -2.3 FIG137877: Hypothetical protein in pyoverdin gene cluster compare
Pf1N1B4_6035 -1.0 -2.3 D-ribose ABC transporter, substrate-binding component RbsB (from data) compare
Pf1N1B4_4485 -1.0 -1.7 membrane protein, putative compare
Pf1N1B4_3942 -1.0 -3.3 Murein-DD-endopeptidase (EC 3.4.99.-) compare
Pf1N1B4_1565 -1.0 -2.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_1057 -1.0 -2.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_656 -1.0 -5.4 Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1) compare
Pf1N1B4_1756 -0.9 -2.6 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases compare
Pf1N1B4_2209 -0.9 -4.2 Exopolyphosphatase (EC 3.6.1.11) compare
Pf1N1B4_880 -0.9 -3.7 Putative preQ0 transporter compare
Pf1N1B4_3775 -0.9 -1.2 FIG00956876: hypothetical protein compare
Pf1N1B4_5718 -0.9 -2.1 Transcriptional regulator, Cro/CI family compare
Pf1N1B4_2339 -0.9 -1.4 COG1872 compare
Pf1N1B4_2218 -0.9 -4.0 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf1N1B4_1234 -0.9 -3.0 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
Pf1N1B4_65 -0.9 -4.5 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf1N1B4_2189 -0.9 -2.6 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_525 -0.9 -2.3 Agmatinase (EC 3.5.3.11) compare
Pf1N1B4_165 -0.9 -2.2 FIG00638667: hypothetical protein compare
Pf1N1B4_5014 -0.9 -1.8 Glutathione reductase (EC 1.8.1.7) compare
Pf1N1B4_4969 -0.9 -2.0 FIG00956189: hypothetical protein compare
Pf1N1B4_3833 -0.9 -5.0 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_5519 -0.9 -2.6 hypothetical protein compare
Pf1N1B4_2401 -0.9 -1.3 Lipoprotein, putative compare
Pf1N1B4_5073 -0.9 -3.0 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf1N1B4_3771 -0.9 -3.5 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf1N1B4_5737 -0.9 -2.1 Nitrate/nitrite transporter compare
Pf1N1B4_5891 -0.9 -1.9 FIG00961753: hypothetical protein compare
Pf1N1B4_3567 -0.9 -5.3 Phenylalanine hydroxylase transcriptional activator PhhR compare
Pf1N1B4_1570 -0.9 -2.5 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
Pf1N1B4_591 -0.9 -3.7 Aldose 1-epimerase compare
Pf1N1B4_5153 -0.9 -3.9 Putative membrane-bound ClpP-class protease associated with aq_911 compare
Pf1N1B4_2724 -0.9 -4.4 Transcriptional regulator, AsnC family compare
Pf1N1B4_652 -0.9 -5.5 Sensory box histidine kinase compare
Pf1N1B4_886 -0.9 -1.7 FIG137478: Hypothetical protein compare
Pf1N1B4_989 -0.8 -4.3 Alginate lyase precursor (EC 4.2.2.3) compare
Pf1N1B4_1399 -0.8 -2.9 FIG003573: hypothetical protein compare
Pf1N1B4_5668 -0.8 -2.4 Peptidase, U7 family compare
Pf1N1B4_1247 -0.8 -2.1 transcriptional regulator, MerR family compare
Pf1N1B4_1116 -0.8 -5.9 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf1N1B4_4957 -0.8 -1.7 Transcriptional regulator, TetR family compare
Pf1N1B4_6041 -0.8 -1.7 Carbon storage regulator compare
Pf1N1B4_3703 -0.8 -2.1 NLP/P60 family protein compare
Pf1N1B4_5989 -0.8 -2.1 FIG067310: hypothetical protein compare
Pf1N1B4_2178 -0.8 -1.6 Regulator of nucleoside diphosphate kinase compare
Pf1N1B4_4166 -0.8 -1.5 Transcriptional regulator, LysR family compare
Pf1N1B4_5508 -0.8 -1.8 hypothetical protein compare
Pf1N1B4_5279 -0.8 -1.7 hypothetical protein compare
Pf1N1B4_2384 -0.8 -5.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf1N1B4_5814 -0.8 -1.9 putative membrane protein compare
Pf1N1B4_3142 -0.8 -1.7 C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS compare
Pf1N1B4_3559 -0.8 -5.9 Aromatic amino acid transport protein AroP compare
Pf1N1B4_3006 -0.8 -3.5 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf1N1B4_1888 -0.8 -2.6 Glutamate-aspartate carrier protein compare
Pf1N1B4_5904 -0.8 -1.4 FIG00955320: hypothetical protein compare
Pf1N1B4_3627 -0.8 -1.3 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf1N1B4_1845 -0.8 -2.3 FIG00954395: hypothetical protein compare
Pf1N1B4_3396 -0.8 -1.8 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf1N1B4_1040 -0.8 -2.8 FolM Alternative dihydrofolate reductase 1 compare
Pf1N1B4_4446 -0.8 -1.4 DNA topoisomerase III (EC 5.99.1.2) compare
Pf1N1B4_673 -0.8 -2.0 MoxR-like ATPases compare
Pf1N1B4_4678 -0.8 -2.7 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf1N1B4_4594 -0.8 -1.5 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) compare
Pf1N1B4_298 -0.8 -2.3 Transcription elongation factor GreB compare
Pf1N1B4_1434 -0.7 -3.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf1N1B4_4897 -0.7 -1.5 Transcriptional regulator, LysR family compare
Pf1N1B4_841 -0.7 -3.0 ABC-type sugar transport systems, ATPase components compare
Pf1N1B4_1865 -0.7 -3.0 Methionine ABC transporter permease protein compare
Pf1N1B4_407 -0.7 -0.9 ADP-ribosylglycohydrolase YegU (EC 3.2.-.-) compare
Pf1N1B4_4303 -0.7 -2.7 DipZ protein compare
Pf1N1B4_3519 -0.7 -2.4 Lipase (EC 3.1.1.3) compare
Pf1N1B4_3909 -0.7 -1.8 Cell division inhibitor-related protein compare
Pf1N1B4_4511 -0.7 -1.9 D-galacturonate dehydrogenase (EC 1.1.1.203) (from data) compare
Pf1N1B4_3435 -0.7 -1.5 ABC transporter for L-Arginine and L-Citrulline, ATPase component (from data) compare
Pf1N1B4_1693 -0.7 -3.5 Cystine ABC transporter, periplasmic cystine-binding protein FliY compare
Pf1N1B4_4301 -0.7 -2.1 hypothetical protein compare
Pf1N1B4_5995 -0.7 -1.7 Transporter, MFS superfamily compare
Pf1N1B4_5620 -0.7 -1.4 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf1N1B4_1872 -0.7 -4.1 Zinc ABC transporter, periplasmic-binding protein ZnuA compare
Pf1N1B4_1035 -0.7 -2.8 Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) compare
Pf1N1B4_2227 -0.7 -1.5 FIG019278: hypothetical protein compare
Pf1N1B4_1236 -0.7 -3.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_5684 -0.7 -2.1 Glyceraldehyde-3-phosphate dehydrogenase, putative compare
Pf1N1B4_1624 -0.7 -3.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_7 -0.7 -2.4 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf1N1B4_3074 -0.7 -1.1 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf1N1B4_2411 -0.7 -1.5 FIG00953568: hypothetical protein compare
Pf1N1B4_5747 -0.7 -1.8 Molybdopterin biosynthesis protein MoeA compare
Pf1N1B4_1402 -0.7 -1.3 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) compare
Pf1N1B4_2981 -0.7 -2.4 hypothetical protein compare
Pf1N1B4_2493 -0.7 -2.0 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf1N1B4_2050 -0.7 -4.1 Rubredoxin-NAD(+) reductase (EC 1.18.1.1) compare
Pf1N1B4_5618 -0.7 -2.0 Excinuclease ABC subunit C compare
Pf1N1B4_2096 -0.7 -1.3 Protein serine/threonine phosphatase PrpC, regulation of stationary phase compare
Pf1N1B4_856 -0.7 -3.0 Type IV pilus biogenesis protein PilF compare
Pf1N1B4_5278 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_1886 -0.7 -2.1 FIG00956005: hypothetical protein compare
Pf1N1B4_3328 -0.7 -1.0 Rhodanese-like domain protein compare
Pf1N1B4_2458 -0.7 -1.5 Sarcosine oxidase gamma subunit (EC 1.5.3.1) compare
Pf1N1B4_1812 -0.7 -1.8 Iron siderophore sensor protein compare
Pf1N1B4_1967 -0.7 -1.9 hypothetical protein compare
Pf1N1B4_2021 -0.7 -1.0 hypothetical protein compare
Pf1N1B4_1667 -0.7 -1.7 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf1N1B4_5269 -0.7 -1.7 hypothetical protein compare
Pf1N1B4_2502 -0.7 -2.9 Coenzyme PQQ synthesis protein B compare
Pf1N1B4_4979 -0.7 -1.9 Transcriptional regulator, AsnC family compare
Pf1N1B4_4053 -0.7 -2.4 Cold shock protein CspD compare
Pf1N1B4_2193 -0.7 -1.6 hypothetical protein compare
Pf1N1B4_35 -0.7 -1.5 hypothetical protein compare
Pf1N1B4_2114 -0.7 -2.7 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf1N1B4_3634 -0.7 -1.9 CheW domain protein compare
Pf1N1B4_4873 -0.7 -2.1 clavaldehyde dehydrogenase compare
Pf1N1B4_2534 -0.6 -1.3 DnaJ-like protein DjlA compare
Pf1N1B4_4418 -0.6 -2.2 hypothetical protein compare
Pf1N1B4_3537 -0.6 -2.5 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf1N1B4_5663 -0.6 -1.3 Periplasmic sugar-binding domain protein compare
Pf1N1B4_932 -0.6 -1.0 FIG00963370: hypothetical protein compare
Pf1N1B4_2284 -0.6 -1.9 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf1N1B4_3981 -0.6 -1.3 Predicted carboxypeptidase compare
Pf1N1B4_2548 -0.6 -3.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf1N1B4_2412 -0.6 -2.0 ATP-dependent 23S rRNA helicase DbpA compare
Pf1N1B4_2621 -0.6 -1.1 PspA/IM30 family protein compare
Pf1N1B4_3750 -0.6 -1.7 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel compare
Pf1N1B4_4274 -0.6 -1.8 5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain compare
Pf1N1B4_2036 -0.6 -1.9 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
Pf1N1B4_3284 -0.6 -2.2 Antitoxin 1 compare
Pf1N1B4_4593 -0.6 -2.3 ABC transporter, periplasmic substrate-binding protein compare


Specific Phenotypes

For 5 genes in this experiment

For stress Thallium(I) acetate in Pseudomonas fluorescens FW300-N1B4

For stress Thallium(I) acetate across organisms