Experiment set2IT035 for Shewanella loihica PV-4

Compare to:

LB with Cisplatin 1 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_2049 +2.2 6.1 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_2572 +2.1 8.6 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1224 +2.1 15.7 sodium:dicarboxylate symporter (RefSeq) compare
Shew_2642 +2.0 4.1 flavodoxin (RefSeq) compare
Shew_3377 +2.0 0.9 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_1202 +1.9 10.4 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_3660 +1.9 15.3 glutathione reductase (RefSeq) compare
Shew_3500 +1.8 3.9 putative endoribonuclease L-PSP (RefSeq) compare
Shew_3681 +1.6 11.7 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_3682 +1.6 11.8 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1186 +1.5 3.3 transcriptional regulator NrdR (RefSeq) compare
Shew_2320 +1.5 6.7 RNA methyltransferase (RefSeq) compare
Shew_0755 +1.5 3.0 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_3131 +1.4 6.8 poly(A) polymerase (RefSeq) compare
Shew_0057 +1.4 3.5 cytoplasmic chaperone TorD family protein (RefSeq) compare
Shew_1078 +1.4 8.4 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_1518 +1.4 1.6 hypothetical protein (RefSeq) compare
Shew_1092 +1.3 4.6 amino acid carrier protein (RefSeq) compare
Shew_0261 +1.3 0.9 hypothetical protein (RefSeq) compare
Shew_1819 +1.3 2.8 GntR family transcriptional regulator (RefSeq) compare
Shew_1590 +1.3 0.9 2OG-Fe(II) oxygenase (RefSeq) compare
Shew_3295 +1.3 7.8 AFG1 family ATPase (RefSeq) compare
Shew_1644 +1.3 1.0 DSBA oxidoreductase (RefSeq) compare
Shew_2554 +1.3 1.3 outer membrane protein W (RefSeq) compare
Shew_1298 guaA +1.2 7.3 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1050 +1.2 3.8 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_3442 +1.2 2.5 hypothetical protein (RefSeq) compare
Shew_3388 +1.2 0.7 hypothetical protein (RefSeq) compare
Shew_0296 +1.2 0.9 heat shock protein Hsp20 (RefSeq) compare
Shew_2573 +1.2 6.1 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_0620 +1.1 1.7 ion transport 2 domain-containing protein (RefSeq) compare
Shew_1601 +1.1 1.5 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2837 +1.1 0.8 transcription elongation factor GreA (RefSeq) compare
Shew_1865 +1.1 3.5 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_3683 +1.1 3.1 extracellular solute-binding protein (RefSeq) compare
Shew_2919 +1.1 1.7 translation-associated GTPase (RefSeq) compare
Shew_0127 +1.1 2.7 LexA repressor (RefSeq) compare
Shew_2646 +1.0 0.8 hypothetical protein (RefSeq) compare
Shew_0301 +1.0 1.1 AsnC family transcriptional regulator (RefSeq) compare
Shew_2416 +1.0 1.3 chorismate synthase (RefSeq) compare
Shew_1563 +1.0 4.5 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_2132 +1.0 2.5 hypothetical protein (RefSeq) compare
Shew_2644 +1.0 2.2 hypothetical protein (RefSeq) compare
Shew_2061 +1.0 1.2 radical SAM domain-containing protein (RefSeq) compare
Shew_1531 grxA +1.0 2.1 glutaredoxin 1 (RefSeq) compare
Shew_1731 +1.0 0.6 histidine triad (HIT) protein (RefSeq) compare
Shew_2481 +1.0 3.6 porin (RefSeq) compare
Shew_0430 +0.9 1.9 histone family protein DNA-binding protein (RefSeq) compare
Shew_1257 +0.9 2.6 DNA repair protein RadC (RefSeq) compare
Shew_3498 rpoZ +0.9 1.9 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_1223 +0.9 0.9 hypothetical protein (RefSeq) compare
Shew_3267 +0.9 3.3 sodium/hydrogen exchanger (RefSeq) compare
Shew_3064 gcvT +0.9 7.7 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_1455 +0.9 0.8 dual specificity protein phosphatase (RefSeq) compare
Shew_1812 +0.9 4.6 23S rRNA m(2)G2445 methyltransferase (RefSeq) compare
Shew_2571 +0.9 3.9 propionyl-CoA carboxylase (RefSeq) compare
Shew_2950 +0.9 1.5 RluA family pseudouridine synthase (RefSeq) compare
Shew_0799 +0.9 1.7 MarR family transcriptional regulator (RefSeq) compare
Shew_1514 upp +0.9 2.5 uracil phosphoribosyltransferase (RefSeq) compare
Shew_1295 +0.9 1.5 hypothetical protein (RefSeq) compare
Shew_2232 +0.9 1.9 heat shock protein 90 (RefSeq) compare
Shew_1782 +0.9 5.6 MarR family transcriptional regulator (RefSeq) compare
Shew_0594 +0.9 2.1 hypothetical protein (RefSeq) compare
Shew_3710 tdh +0.9 6.0 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_2910 +0.8 1.0 hypothetical protein (RefSeq) compare
Shew_3265 +0.8 1.3 CutA1 divalent ion tolerance protein (RefSeq) compare
Shew_3261 +0.8 1.3 thiopurine S-methyltransferase (RefSeq) compare
Shew_2406 +0.8 1.2 AraC family transcriptional regulator (RefSeq) compare
Shew_1287 +0.8 2.8 hypothetical protein (RefSeq) compare
Shew_0121 +0.8 1.0 hypothetical protein (RefSeq) compare
Shew_0695 +0.8 1.1 hypothetical protein (RefSeq) compare
Shew_2327 +0.8 0.5 hypothetical protein (RefSeq) compare
Shew_0433 +0.8 1.9 hypothetical protein (RefSeq) compare
Shew_2228 +0.8 3.3 inosine kinase (RefSeq) compare
Shew_0220 +0.8 2.5 phosphoglycolate phosphatase (RefSeq) compare
Shew_2282 +0.8 1.0 Fis family transcriptional regulator (RefSeq) compare
Shew_0091 +0.8 3.3 molybdopterin biosynthesis MoaE (RefSeq) compare
Shew_3522 +0.8 0.9 hypothetical protein (RefSeq) compare
Shew_0546 +0.8 2.1 hypothetical protein (RefSeq) compare
Shew_2194 +0.8 0.5 hypothetical protein (RefSeq) compare
Shew_3378 +0.8 0.8 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_0678 +0.8 1.9 protoporphyrinogen oxidase (RefSeq) compare
Shew_2429 +0.8 0.7 hypothetical protein (RefSeq) compare
Shew_2926 +0.8 1.4 CBS domain-containing protein (RefSeq) compare
Shew_0438 +0.7 0.6 GumN family protein (RefSeq) compare
Shew_0026 +0.7 1.0 hypothetical protein (RefSeq) compare
Shew_2804 +0.7 0.9 type IV pilus assembly PilZ (RefSeq) compare
Shew_2199 +0.7 2.0 histidinol-phosphate aminotransferase (RefSeq) compare
Shew_0462 +0.7 0.6 hypothetical protein (RefSeq) compare
Shew_0718 +0.7 2.0 cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) compare
Shew_1470 +0.7 3.2 sulfatase (RefSeq) compare
Shew_0056 +0.7 4.7 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_1018 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_2059 +0.7 2.1 hypothetical protein (RefSeq) compare
Shew_2278 +0.7 0.8 LysR family transcriptional regulator (RefSeq) compare
Shew_3537 +0.7 1.4 hypothetical protein (RefSeq) compare
Shew_1932 cls +0.7 2.4 cardiolipin synthetase (RefSeq) compare
Shew_1144 +0.7 2.4 hypothetical protein (RefSeq) compare
Shew_2035 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_0364 +0.7 1.4 MshA, mannose-sensitive haemaglutinin (RefSeq) compare
Shew_3512 +0.7 2.4 acyl carrier protein (RefSeq) compare
Shew_3709 +0.7 4.4 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_0570 +0.7 0.5 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_1163 +0.7 1.5 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0614 +0.7 2.9 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_2403 +0.7 0.9 arylesterase (RefSeq) compare
Shew_3167 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_0421 +0.7 1.0 phage shock protein C, PspC (RefSeq) compare
Shew_1828 +0.7 2.2 peptidoglycan binding domain-containing protein (RefSeq) compare
Shew_2892 +0.7 2.0 major facilitator transporter (RefSeq) compare
Shew_2026 +0.7 1.5 alanine dehydrogenase (RefSeq) compare
Shew_2766 +0.7 1.7 thiamine biosynthesis protein ThiI (RefSeq) compare
Shew_2957 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_2389 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_0086 +0.6 4.2 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_0932 +0.6 0.9 radical SAM domain-containing protein (RefSeq) compare
Shew_2584 +0.6 3.9 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_1510 +0.6 1.0 peptidase M28 (RefSeq) compare
Shew_1867 +0.6 2.0 hypothetical protein (RefSeq) compare
Shew_2785 +0.6 0.5 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_0560 +0.6 2.0 hypothetical protein (RefSeq) compare
Shew_1210 +0.6 1.5 stationary-phase survival protein SurE (RefSeq) compare
Shew_0846 +0.6 1.5 nitrogen regulatory protein P-II (RefSeq) compare
Shew_1110 +0.6 1.5 nitrogen regulatory protein P-II (RefSeq) compare
Shew_2241 +0.6 0.8 hypothetical protein (RefSeq) compare
Shew_2882 +0.6 1.4 S-ribosylhomocysteinase (RefSeq) compare
Shew_3625 +0.6 1.5 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1227 +0.6 0.7 glutamate--cysteine ligase (RefSeq) compare
Shew_3685 +0.6 2.9 ABC transporter-related protein (RefSeq) compare
Shew_1606 +0.6 0.5 hypothetical protein (RefSeq) compare
Shew_0383 +0.6 2.2 malate dehydrogenase (RefSeq) compare
Shew_3271 +0.6 2.6 galactokinase (RefSeq) compare
Shew_2900 +0.6 1.9 hypothetical protein (RefSeq) compare
Shew_2175 nhaB +0.6 2.6 sodium/proton antiporter (RefSeq) compare
Shew_1023 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_0788 +0.6 1.5 dienelactone hydrolase (RefSeq) compare
Shew_1929 +0.6 2.5 methyl-accepting chemotaxis sensory transducer (RefSeq) compare
Shew_0834 +0.6 0.5 hypothetical protein (RefSeq) compare
Shew_0616 +0.6 1.4 SH3 domain-containing protein (RefSeq) compare
Shew_0342 +0.6 1.8 hypothetical protein (RefSeq) compare
Shew_0343 +0.6 0.7 hypothetical protein (RefSeq) compare
Shew_0055 +0.6 3.8 hypothetical protein (RefSeq) compare
Shew_1439 +0.6 2.9 maleylacetoacetate isomerase (RefSeq) compare
Shew_3509 +0.6 2.4 hypothetical protein (RefSeq) compare
Shew_2185 +0.6 2.9 septum site-determining protein MinD (RefSeq) compare
Shew_0047 +0.6 4.0 molybdopterin biosynthesis protein MoeB (RefSeq) compare
Shew_0842 +0.6 1.5 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_1851 +0.6 0.4 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_1769 +0.6 0.7 NapD family protein (RefSeq) compare
Shew_1391 +0.6 0.6 CheW protein (RefSeq) compare
Shew_3487 pyrE +0.6 1.8 orotate phosphoribosyltransferase (RefSeq) compare
Shew_1133 +0.6 3.0 hypothetical protein (RefSeq) compare
Shew_1776 +0.6 2.0 acetolactate synthase 3 catalytic subunit (RefSeq) compare
Shew_3063 +0.5 0.8 glycine cleavage system protein H (RefSeq) compare
Shew_2700 +0.5 1.5 antibiotic biosynthesis monooxygenase (RefSeq) compare
Shew_0707 +0.5 2.0 YbaK/prolyl-tRNA synthetase associated region (RefSeq) compare
Shew_0621 +0.5 1.3 hypothetical protein (RefSeq) compare
Shew_3095 +0.5 2.1 hypothetical protein (RefSeq) compare
Shew_2708 +0.5 1.1 Na(+)-translocating NADH-quinone reductase subunit B (RefSeq) compare
Shew_3052 +0.5 1.8 AraC family transcriptional regulator (RefSeq) compare
Shew_3525 fabG +0.5 1.9 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_1458 +0.5 2.7 serine/threonine transporter SstT (RefSeq) compare
Shew_1926 +0.5 1.2 transketolase, central region (RefSeq) compare
Shew_2570 +0.5 4.1 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1797 +0.5 0.7 paraquat-inducible protein A (RefSeq) compare
Shew_0722 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_1483 +0.5 1.4 hypothetical protein (RefSeq) compare
Shew_1781 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_0860 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_2121 +0.5 1.6 diguanylate cyclase (RefSeq) compare
Shew_1313 +0.5 1.1 TetR family transcriptional regulator (RefSeq) compare
Shew_2153 +0.5 0.6 LysR family transcriptional regulator (RefSeq) compare
Shew_1418 +0.5 2.5 UTP-glucose-1-phosphate uridylyltransferase GalU (RefSeq) compare
Shew_2795 +0.5 1.7 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_0372 +0.5 1.4 hypothetical protein (RefSeq) compare
Shew_1183 +0.5 2.6 putative ABC transporter ATP-binding protein (RefSeq) compare
Shew_2652 +0.5 1.2 hypothetical protein (RefSeq) compare
Shew_0729 +0.5 2.0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase (RefSeq) compare
Shew_1969 +0.5 1.0 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_2724 +0.5 1.6 indigoidine synthase A family protein (RefSeq) compare
Shew_2739 +0.5 1.4 Fmu (Sun) domain-containing protein (RefSeq) compare
Shew_3379 +0.5 1.0 hypothetical protein (RefSeq) compare
Shew_3499 +0.5 1.6 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_3687 +0.5 3.3 molybdopterin-guanine dinucleotide biosynthesis protein B (RefSeq) compare
Shew_3653 +0.5 0.6 hypothetical protein (RefSeq) compare
Shew_1884 +0.5 1.4 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_1044 nhaR +0.5 1.5 transcriptional activator NhaR (RefSeq) compare
Shew_2340 +0.5 1.8 redoxin domain-containing protein (RefSeq) compare
Shew_2106 +0.5 1.8 hypothetical protein (RefSeq) compare
Shew_1246 +0.5 0.7 hypothetical protein (RefSeq) compare
Shew_1477 +0.5 1.4 anti-ECFsigma factor, ChrR (RefSeq) compare
Shew_1194 +0.5 1.1 glutathione-dependent formaldehyde-activating, GFA (RefSeq) compare
Shew_3255 +0.5 0.5 hypothetical protein (RefSeq) compare
Shew_2155 +0.5 1.1 4-hydroxyphenylpyruvate dioxygenase (RefSeq) compare
Shew_3371 +0.5 1.2 hypothetical protein (RefSeq) compare
Shew_1281 +0.5 0.9 hypothetical protein (RefSeq) compare
Shew_0054 +0.5 2.3 hypothetical protein (RefSeq) compare
Shew_2821 +0.5 1.6 lipoprotein NlpI (RefSeq) compare
Shew_3684 +0.5 2.7 binding-protein-dependent transport systems inner membrane component (RefSeq) compare
Shew_3345 +0.5 1.6 lipid kinase (RefSeq) compare


Specific Phenotypes

For 6 genes in this experiment

For stress Cisplatin in Shewanella loihica PV-4

For stress Cisplatin across organisms