Experiment set2IT034 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS05975		+1.1	2.8	hypothetical protein
MMP_RS02745		+0.8	2.7	hypothetical protein
MMP_RS07345		+0.8	4.9	glycine synthesis protein GlyXL (from data)
MMP_RS03300		+0.7	0.9	TOBE domain-containing protein
MMP_RS01650		+0.6	1.0	sulfurtransferase TusA family protein
MMP_RS07125		+0.6	3.1	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS02605		+0.6	0.9	MotA/TolQ/ExbB proton channel family protein
MMP_RS09025		+0.6	1.2	hypothetical protein
MMP_RS03450		+0.6	2.1	glycine synthesis protein GlyXS (from data)
MMP_RS08500		+0.6	3.1	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS07835		+0.5	2.1	TldD/PmbA family protein
MMP_RS07840		+0.5	2.4	ribonuclease III
MMP_RS05970		+0.5	1.7	class II SORL domain-containing protein
MMP_RS07650		+0.5	4.1	TldD/PmbA family protein
MMP_RS01890		+0.5	2.0	nucleotide sugar dehydrogenase
MMP_RS08775		+0.5	3.0	methanogenesis marker 9 domain-containing protein
MMP_RS03215		+0.5	3.6	MBL fold metallo-hydrolase
MMP_RS06975		+0.5	1.5	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS08980		+0.5	3.0	hypothetical protein
MMP_RS08675		+0.5	1.6	class III signal peptide-containing protein
MMP_RS06545		+0.5	2.6	ferredoxin family protein
MMP_RS08620		+0.5	3.3	flagellar accessory protein FlaH
MMP_RS06610		+0.5	2.4	DUF2334 domain-containing protein
MMP_RS07130		+0.5	3.2	coenzyme F420 hydrogenase subunit gamma
MMP_RS03535		+0.5	1.5	helix-turn-helix transcriptional regulator
MMP_RS07120		+0.5	3.4	coenzyme F420 hydrogenase subunit alpha
MMP_RS06910		+0.5	3.5	RlmF-related methyltransferase
MMP_RS02595		+0.5	1.0	putative zinc-binding protein
MMP_RS08615		+0.5	1.4	flagellar protein G
MMP_RS08265		+0.4	2.2	rubrerythrin
MMP_RS09050		+0.4	2.3	CAP domain-containing protein
MMP_RS02675		+0.4	1.4	hypothetical protein
MMP_RS05965		+0.4	1.4	carboxymuconolactone decarboxylase family protein
MMP_RS07900		+0.4	1.3	YeeE/YedE family protein
MMP_RS08430		+0.4	3.1	HAD family hydrolase
MMP_RS06520		+0.4	2.0	DUF1786 domain-containing protein
MMP_RS07560		+0.4	2.1	prefoldin subunit alpha
MMP_RS08455		+0.4	2.2	multiprotein bridging factor aMBF1
MMP_RS07970		+0.4	1.9	hypothetical protein
MMP_RS01435		+0.4	1.9	DMT family transporter
MMP_RS00675		+0.4	0.5	nitroreductase family protein
MMP_RS08470		+0.4	2.6	ATP-binding cassette domain-containing protein
MMP_RS08700		+0.4	2.8	hypothetical protein
MMP_RS07985		+0.4	3.3	nitroreductase family protein
MMP_RS06540		+0.4	1.6	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS01370		+0.4	2.7	acetate--CoA ligase family protein
MMP_RS01420		+0.4	1.3	hypothetical protein
MMP_RS06190		+0.4	1.9	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS08480		+0.4	3.0	molybdate ABC transporter substrate-binding protein
MMP_RS00545		+0.4	1.5	XRE family transcriptional regulator
MMP_RS08395		+0.4	2.6	DsrE family protein
MMP_RS08205		+0.4	2.7	stage II sporulation protein M
MMP_RS06485		+0.3	0.6	zinc ribbon domain-containing protein
MMP_RS01150		+0.3	1.8	aldo/keto reductase
MMP_RS08280		+0.3	1.6	proteasome assembly chaperone family protein
MMP_RS08830		+0.3	1.6	GTP-binding protein
MMP_RS08080		+0.3	2.7	YchF/TatD family DNA exonuclease
MMP_RS02370		+0.3	1.8	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS08090		+0.3	1.3	hypothetical protein
MMP_RS01260		+0.3	2.2	HDIG domain-containing protein
MMP_RS06165		+0.3	2.8	ABC transporter permease
MMP_RS06495		+0.3	1.3	YkgJ family cysteine cluster protein
MMP_RS03340		+0.3	0.5	ABC transporter ATP-binding protein
MMP_RS08390		+0.3	1.7	DUF5400 domain-containing protein
MMP_RS08245		+0.3	1.8	DUF4013 domain-containing protein
MMP_RS08130		+0.3	2.8	IGHMBP2 family helicase
MMP_RS08325		+0.3	2.5	hypothetical protein
MMP_RS07135		+0.3	2.3	coenzyme F420 hydrogenase subunit beta
MMP_RS01635		+0.3	2.2	thiamine pyrophosphate-dependent enzyme
MMP_RS08260		+0.3	1.9	DUF99 family protein
MMP_RS07895		+0.3	1.6	cytochrome c
MMP_RS05720		+0.3	1.1	signal recognition particle subunit SRP19/SEC65 family protein
MMP_RS08415		+0.3	1.2	radical SAM protein
MMP_RS01430		+0.3	2.2	mechanosensitive ion channel family protein
MMP_RS02310		+0.3	0.9	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS01990		+0.3	1.7	hypothetical protein
MMP_RS01055		+0.3	1.6	hypothetical protein
MMP_RS07550		+0.3	2.2	L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
MMP_RS01775		+0.3	1.1	TIGR00297 family protein
MMP_RS08555		+0.3	1.5	hypothetical protein
MMP_RS03465		+0.3	0.6	adenine phosphoribosyltransferase
MMP_RS01485		+0.3	2.0	right-handed parallel beta-helix repeat-containing protein
MMP_RS00645		+0.3	2.3	iron ABC transporter permease
MMP_RS07590		+0.3	2.4	hypothetical protein
MMP_RS00740		+0.3	1.4	cyclase family protein
MMP_RS08275		+0.3	2.0	hypothetical protein
MMP_RS00155		+0.3	1.6	heavy metal-binding domain-containing protein
MMP_RS07805		+0.3	2.0	ABC transporter permease
MMP_RS02975		+0.3	1.1	DUF2124 domain-containing protein
MMP_RS07855		+0.3	2.1	class I SAM-dependent methyltransferase
MMP_RS03735		+0.3	2.0	indolepyruvate ferredoxin oxidoreductase subunit alpha
MMP_RS08610		+0.3	2.1	flagellar protein F
MMP_RS06465		+0.3	2.2	NERD domain-containing protein
MMP_RS08085		+0.3	1.9	hypothetical protein
MMP_RS08835		+0.3	1.8	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS06005		+0.3	1.2	heavy-metal-associated domain-containing protein
MMP_RS07915		+0.3	1.7	DUF4870 domain-containing protein
MMP_RS08485		+0.3	1.8	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS03085		+0.3	2.0	endonuclease III
MMP_RS09065		+0.3	2.2	hypothetical protein
MMP_RS02175		+0.3	0.3	DUF1611 domain-containing protein
MMP_RS01275		+0.3	1.7	class III signal peptide-containing protein
MMP_RS00185		+0.3	2.3	potassium channel protein
MMP_RS08640		+0.3	2.2	TIM barrel protein
MMP_RS07155		+0.3	2.0	MFS transporter
MMP_RS06930		+0.3	2.1	MBL fold metallo-hydrolase
MMP_RS01110		+0.3	0.9	FmdE family protein
MMP_RS08400		+0.3	1.1	MJ0307 family thioredoxin
MMP_RS07715		+0.3	1.8	YfcE family phosphodiesterase
MMP_RS07850		+0.3	0.8	prephenate dehydratase
MMP_RS02500		+0.3	1.4	minichromosome maintenance protein MCM
MMP_RS09060		+0.3	2.3	hypothetical protein
MMP_RS08750		+0.3	1.3	hypothetical protein
MMP_RS08665		+0.3	2.2	hypothetical protein
MMP_RS04060		+0.2	1.5	hypothetical protein
MMP_RS08850		+0.2	2.2	hypothetical protein
MMP_RS02320		+0.2	1.9	glutamate-cysteine ligase family protein
MMP_RS01115		+0.2	1.8	molybdopterin molybdotransferase MoeA
MMP_RS07185		+0.2	1.9	pyridoxal phosphate-dependent aminotransferase
MMP_RS03125		+0.2	1.0	cell division ATPase MinD
MMP_RS06460		+0.2	0.7	pyrimidine dimer DNA glycosylase/endonuclease V
MMP_RS06585		+0.2	0.6	DMT family protein
MMP_RS06055		+0.2	1.2	peroxiredoxin
MMP_RS03225		+0.2	1.2	acetolactate decarboxylase
MMP_RS00085		+0.2	1.7	DNA cytosine methyltransferase
MMP_RS04530		+0.2	1.6	ABC transporter permease
MMP_RS05360		+0.2	0.9	hypothetical protein
MMP_RS01785		+0.2	1.4	hypothetical protein
MMP_RS08285		+0.2	1.3	serine/threonine protein kinase
MMP_RS05780		+0.2	1.6	multidrug resistance efflux transporter family protein
MMP_RS06045		+0.2	1.2	DNA polymerase
MMP_RS06550		+0.2	1.5	AMP-binding protein
MMP_RS08405		+0.2	1.7	MFS transporter
MMP_RS08475		+0.2	1.0	ABC transporter permease
MMP_RS04225		+0.2	1.4	hypothetical protein
MMP_RS07145		+0.2	1.2	AmmeMemoRadiSam system protein B
MMP_RS06655		+0.2	1.6	glycoside hydrolase family 15 protein
MMP_RS06060		+0.2	1.5	hypothetical protein
MMP_RS04100		+0.2	1.0	hypothetical protein
MMP_RS00950		+0.2	1.4	site-2 protease family protein
MMP_RS00955		+0.2	1.7	coenzyme gamma-F420-2:alpha-L-glutamate ligase
MMP_RS02025		+0.2	1.5	DNA-directed DNA polymerase
MMP_RS01460		+0.2	1.0	hypothetical protein
MMP_RS05900		+0.2	1.6	tetratricopeptide repeat protein
MMP_RS01285		+0.2	1.5	hypothetical protein
MMP_RS08755		+0.2	1.6	sodium:solute symporter family protein
MMP_RS08625		+0.2	1.5	type II/IV secretion system ATPase subunit
MMP_RS08380		+0.2	1.5	phosphatase PAP2 family protein
MMP_RS01630		+0.2	1.4	N-glycosylase/DNA lyase
MMP_RS06710		+0.2	0.9	selenium-binding protein
MMP_RS04145		+0.2	0.5	hypothetical protein
MMP_RS04580		+0.2	1.8	hypothetical protein
MMP_RS00630		+0.2	1.7	ECF transporter S component
MMP_RS07770		+0.2	1.2	alanine racemase
MMP_RS08490		+0.2	1.8	hypothetical protein
MMP_RS00055		+0.2	1.7	DUF2254 domain-containing protein
MMP_RS05455		+0.2	1.1	DUF167 domain-containing protein
MMP_RS00635		+0.2	1.2	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS05110		+0.2	1.1	16S ribosomal RNA methyltransferase A
MMP_RS01295		+0.2	1.3	hypothetical protein
MMP_RS03395		+0.2	0.8	hypothetical protein
MMP_RS06965		+0.2	1.1	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS08310		+0.2	0.6	TMEM165/GDT1 family protein
MMP_RS00395		+0.2	0.5	MGMT family protein
MMP_RS08575		+0.2	1.7	hypothetical protein
MMP_RS08845		+0.2	1.5	archaellum operon transcriptional activator EarA family protein
MMP_RS01125		+0.2	0.9	thioredoxin family protein
MMP_RS08630		+0.2	1.2	archaellar assembly protein FlaJ
MMP_RS05290		+0.2	1.4	TetR/AcrR family transcriptional regulator
MMP_RS05675		+0.2	0.7	phosphate ABC transporter ATP-binding protein PstB
MMP_RS08385		+0.2	1.1	ABC transporter substrate-binding protein
MMP_RS06300		+0.2	1.1	ABC transporter substrate-binding protein
MMP_RS05685		+0.2	1.2	winged helix-turn-helix domain-containing protein
MMP_RS00565		+0.2	0.7	CBS domain-containing protein
MMP_RS07115		+0.2	1.1	MBL fold metallo-hydrolase
MMP_RS00560		+0.2	1.4	cation:proton antiporter
MMP_RS06990		+0.2	1.0	CatB-related O-acetyltransferase
MMP_RS03220		+0.2	0.7	RNA 2' 3'-cyclic phosphodiesterase
MMP_RS01955		+0.2	0.3	hypothetical protein
MMP_RS06065		+0.2	1.5	iron ABC transporter substrate-binding protein
MMP_RS08410		+0.2	0.9	DUF169 domain-containing protein
MMP_RS04815		+0.2	1.4	chemotaxis protein CheD
MMP_RS00285		+0.2	0.9	TIGR04013 family B12-binding domain/radical SAM domain-containing protein
MMP_RS06665		+0.2	1.2	glycogen/starch synthase
MMP_RS07140		+0.2	1.4	TIGR00341 family protein
MMP_RS02570		+0.2	1.5	cation:proton antiporter
MMP_RS07595		+0.2	1.2	hypothetical protein
MMP_RS05680		+0.2	1.1	phosphate signaling complex protein PhoU
MMP_RS04055		+0.2	0.4	hypothetical protein
MMP_RS01655		+0.2	0.5	DsrE family protein
MMP_RS02810		+0.2	1.0	hypothetical protein
MMP_RS06660		+0.2	1.2	glycosyltransferase family 4 protein
MMP_RS00480		+0.2	1.2	hypothetical protein
MMP_RS05275		+0.2	1.2	AI-2E family transporter
MMP_RS00540		+0.2	1.1	PLP-dependent aminotransferase family protein
MMP_RS04435		+0.2	1.2	pyridoxamine 5'-phosphate oxidase family protein
MMP_RS07100		+0.2	1.2	hypothetical protein
MMP_RS01135		+0.2	1.3	molybdate ABC transporter substrate-binding protein
MMP_RS08670		+0.2	0.7	metallophosphoesterase
MMP_RS03900		+0.2	1.0	minichromosome maintenance protein MCM

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in rich t2 experiments