Experiment set2IT034 for Bifidobacterium breve UCC2003

Compare to:

CDM1 without Biotin

200 most important genes:

  gene name fitness t score description  
BBR_RS11205 -7.4 -5.1 HPr family phosphocarrier protein compare
BBR_RS11210 -7.3 -7.2 phosphoenolpyruvate--protein phosphotransferase compare
BBR_RS18695 -7.3 -7.1 PRD domain-containing protein compare
BBR_RS18735 -6.8 -19.1 hypothetical protein compare
BBR_RS16820 -6.2 -4.3 RNA polymerase sigma factor RpoE compare
BBR_RS10625 -6.2 -3.8 FHA domain-containing protein compare
BBR_RS11015 -6.1 -10.2 aspartate kinase compare
BBR_RS11025 -6.1 -14.7 aspartate-semialdehyde dehydrogenase compare
BBR_RS19475 -6.0 -20.2 AEC family transporter compare
BBR_RS12235 -5.9 -1.9 hypothetical protein compare
BBR_RS17375 -5.9 -5.8 amino acid ABC transporter ATP-binding protein compare
BBR_RS12995 -5.9 -9.1 4-hydroxy-tetrahydrodipicolinate synthase compare
BBR_RS17370 -5.9 -5.7 ABC transporter substrate-binding protein compare
BBR_RS11020 -5.8 -13.1 ACT domain-containing protein compare
BBR_RS17365 -5.8 -4.0 ABC transporter permease compare
BBR_RS18570 -5.8 -5.6 phosphoserine transaminase compare
BBR_RS19535 -5.7 -11.0 homoserine kinase (EC 2.7.1.39) (from data) compare
BBR_RS10445 -5.6 -6.7 HlyC/CorC family transporter compare
BBR_RS13040 -5.5 -3.8 CHAP domain-containing protein compare
BBR_RS17615 -5.5 -11.2 phosphoserine phosphatase SerB compare
BBR_RS11720 -5.4 -9.1 DUF2469 domain-containing protein compare
BBR_RS18955 -5.3 -15.9 bifunctional acetaldehyde-CoA/alcohol dehydrogenase compare
BBR_RS18690 -5.1 -7.8 diacylglycerol kinase compare
BBR_RS17990 -5.1 -15.7 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase compare
BBR_RS10660 -5.0 -24.7 esterase compare
BBR_RS19355 -5.0 -2.7 tRNA-Gly compare
BBR_RS16970 -5.0 -5.9 phosphoglycerate dehydrogenase compare
BBR_RS15675 -4.9 -6.7 ADP-forming succinate--CoA ligase subunit beta compare
BBR_RS17460 -4.8 -9.3 TPM domain-containing protein compare
BBR_RS12900 -4.8 -4.0 DeoR/GlpR transcriptional regulator compare
BBR_RS16610 -4.8 -6.5 hypothetical protein compare
BBR_RS19240 -4.7 -16.2 LacI family transcriptional regulator compare
BBR_RS15070 -4.7 -3.2 endolytic transglycosylase MltG compare
BBR_RS19760 -4.6 -2.9 polysaccharide ABC transporter ATPase compare
BBR_RS16430 -4.6 -3.1 nucleotide pyrophosphatase compare
BBR_RS13035 -4.5 -3.1 ABC transporter permease compare
BBR_RS17290 -4.5 -10.1 Fused ATP-binding protein and permease of ABC transporter compare
BBR_RS14070 -4.4 -5.2 threonine synthase (EC 4.2.3.1) (from data) compare
BBR_RS15170 -4.4 -6.0 HlyC/CorC family transporter compare
BBR_RS16670 -4.4 -6.3 hypothetical protein compare
BBR_RS11675 -4.4 -2.7 hypothetical protein compare
BBR_RS16155 -4.4 -10.7 isocitrate dehydrogenase (NADP(+)) compare
BBR_RS12545 -4.3 -6.2 DUF4012 domain-containing protein compare
BBR_RS16750 -4.3 -2.9 ParA family protein compare
BBR_RS13820 -4.2 -1.9 ATP-binding protein compare
BBR_RS11540 -4.2 -4.0 DUF1727 domain-containing protein compare
BBR_RS19740 -4.2 -19.9 DUF2142 domain-containing protein compare
BBR_RS14365 -4.1 -7.8 hypothetical protein compare
BBR_RS13030 -4.1 -4.0 cell division ATP-binding protein FtsE compare
BBR_RS14625 -4.0 -8.6 pyrroline-5-carboxylate reductase compare
BBR_RS12905 -4.0 -5.0 galactose-1-phosphate uridylyltransferase compare
BBR_RS16675 -4.0 -3.8 prephenate dehydrogenase/arogenate dehydrogenase family protein compare
BBR_RS13830 -3.9 -1.2 DUF4191 domain-containing protein compare
BBR_RS10620 -3.8 -7.8 phosphoprotein phosphatase compare
BBR_RS15080 -3.8 -2.6 chorismate synthase compare
BBR_RS19470 -3.7 -22.4 succinyl-diaminopimelate desuccinylase compare
BBR_RS12460 -3.7 -9.0 LacI family DNA-binding transcriptional regulator compare
BBR_RS15180 -3.7 -10.6 long-chain fatty acid--CoA ligase compare
BBR_RS19120 -3.7 -14.9 helicase compare
BBR_RS19555 -3.6 -25.2 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
BBR_RS18745 -3.6 -2.1 bifunctional riboflavin kinase/FMN adenylyltransferase compare
BBR_RS15680 -3.6 -8.3 succinate--CoA ligase subunit alpha compare
BBR_RS15520 -3.6 -2.5 shikimate 5-dehydrogenase compare
BBR_RS19700 -3.6 -23.6 ATP-dependent chaperone ClpB compare
BBR_RS19190 -3.5 -6.4 3-deoxy-7-phosphoheptulonate synthase compare
BBR_RS16555 -3.5 -1.1 DNA translocase FtsK compare
BBR_RS14205 -3.4 -4.8 hypothetical protein compare
BBR_RS11515 -3.4 -18.8 ammonium transporter compare
BBR_RS14210 -3.4 -2.9 hypothetical protein compare
BBR_RS14215 -3.4 -4.3 peptidase compare
BBR_RS17905 -3.4 -27.3 2-hydroxyglutaryl-CoA dehydratase activator compare
BBR_RS14260 -3.4 -1.5 ABC transporter ATP-binding protein compare
BBR_RS11470 -3.3 -1.5 6-phosphogluconolactonase compare
BBR_RS19945 -3.3 -10.5 MarR family transcriptional regulator compare
BBR_RS15085 -3.3 -1.8 3-dehydroquinate synthase compare
BBR_RS16600 -3.3 -12.5 aconitate hydratase AcnA compare
BBR_RS12660 -3.3 -9.6 EpsG family protein compare
BBR_RS13740 -3.3 -6.1 DUF3052 domain-containing protein compare
BBR_RS14370 -3.2 -4.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BBR_RS13700 -3.2 -12.3 diaminopimelate epimerase compare
BBR_RS13735 -3.1 -1.4 Lon protease compare
BBR_RS15300 -3.0 -5.1 peroxiredoxin compare
BBR_RS14190 -3.0 -10.1 transcriptional regulator compare
BBR_RS12760 -3.0 -9.6 hypothetical protein compare
BBR_RS13805 -3.0 -2.7 hypothetical protein compare
BBR_RS11680 -2.9 -12.5 23S rRNA methyltransferase compare
BBR_RS19390 -2.9 -2.8 hypothetical protein compare
BBR_RS18725 -2.9 -4.3 ribonuclease HI compare
BBR_RS12770 -2.9 -5.2 hypothetical protein compare
BBR_RS17360 -2.9 -5.7 amino acid ABC transporter permease compare
BBR_RS20920 -2.9 -4.7 hypothetical protein compare
BBR_RS13375 -2.8 -6.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BBR_RS11505 -2.8 -15.1 TetR/AcrR family transcriptional regulator compare
BBR_RS14265 -2.8 -6.2 Solute-binding protein of ABC transporter system for metals compare
BBR_RS12375 -2.8 -2.1 pantetheine-phosphate adenylyltransferase compare
BBR_RS20465 -2.8 -9.5 chromosome partitioning protein compare
BBR_RS19125 -2.7 -10.9 hypothetical protein compare
BBR_RS13455 -2.7 -4.0 formate-dependent phosphoribosylglycinamide formyltransferase compare
BBR_RS11355 -2.7 -8.4 hypothetical protein compare
BBR_RS16845 -2.6 -1.9 bifunctional folylpolyglutamate synthase/dihydrofolate synthase compare
BBR_RS14660 -2.6 -2.5 transcriptional regulator compare
BBR_RS20935 -2.6 -3.1 hypothetical protein compare
BBR_RS19155 -2.6 -8.2 phosphate ABC transporter, permease protein PstA compare
BBR_RS19095 -2.6 -10.9 magnesium transporter compare
BBR_RS19375 -2.6 -1.8 acyl-CoA carboxylase subunit beta compare
BBR_RS14655 -2.6 -6.3 AraC family transcriptional regulator compare
BBR_RS15845 -2.5 -1.1 hypothetical protein compare
BBR_RS15360 -2.5 -3.0 hypothetical protein compare
BBR_RS12810 -2.5 -9.1 hypothetical protein compare
BBR_RS13910 -2.3 -1.7 arginine repressor compare
BBR_RS12635 -2.3 -13.1 polysaccharide biosynthesis protein compare
BBR_RS18215 -2.3 -7.3 AI-2E family transporter compare
BBR_RS18555 -2.3 -9.4 NlpC/P60 family protein compare
BBR_RS13420 -2.3 -2.5 DUF4230 domain-containing protein compare
BBR_RS12705 -2.2 -10.3 hypothetical protein compare
BBR_RS15090 -2.2 -1.0 type II 3-dehydroquinate dehydratase compare
BBR_RS10755 -2.2 -5.3 adenylosuccinate synthase compare
BBR_RS17510 -2.2 -7.8 VWA domain-containing protein compare
BBR_RS18700 -2.2 -3.9 PTS beta-glucoside transporter subunit EIIBCA compare
BBR_RS15880 -2.2 -3.0 hypothetical protein compare
BBR_RS13125 -2.2 -1.2 ABC transporter permease compare
BBR_RS15330 -2.2 -4.6 hypothetical protein compare
BBR_RS13070 -2.2 -1.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
BBR_RS17490 -2.2 -10.9 MoxR family ATPase compare
BBR_RS19540 -2.1 -2.1 homoserine dehydrogenase compare
BBR_RS12630 -2.1 -12.4 glycosyltransferase family 1 protein compare
BBR_RS16575 -2.1 -6.9 (p)ppGpp synthetase compare
BBR_RS16940 -2.1 -2.4 hypothetical protein compare
BBR_RS17495 -2.1 -7.8 DUF58 domain-containing protein compare
BBR_RS14665 -2.1 -7.0 MATE family efflux transporter compare
BBR_RS12640 -2.1 -9.1 glycosyl transferase compare
BBR_RS17505 -2.1 -10.3 VWA domain-containing protein compare
BBR_RS12980 -2.0 -11.7 ATP-dependent DNA helicase UvrD/REP family compare
BBR_RS11715 -2.0 -12.5 N-acetyltransferase compare
BBR_RS16255 -2.0 -2.5 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE compare
BBR_RS13445 -2.0 -8.2 phosphoribosylformylglycinamidine synthase compare
BBR_RS14330 -2.0 -1.3 glycogen debranching enzyme GlgX compare
BBR_RS11500 -2.0 -10.3 glycosyltransferase family 2 protein compare
BBR_RS16975 -2.0 -3.3 transcriptional repressor NrdR compare
BBR_RS16425 -2.0 -1.5 DUF3071 domain-containing protein compare
BBR_RS12975 -1.9 -10.4 ATP-dependent DNA helicase UvrD/REP family compare
BBR_RS19050 -1.9 -13.1 succinyldiaminopimelate transaminase compare
BBR_RS19270 -1.9 -1.0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase compare
BBR_RS19165 -1.9 -2.4 phosphate ABC transporter substrate-binding protein PstS compare
BBR_RS13370 -1.9 -2.2 phosphoribosylamine--glycine ligase compare
BBR_RS12835 -1.9 -4.8 thioredoxin compare
BBR_RS18050 -1.9 -3.1 threonylcarbamoyl-AMP synthase compare
BBR_RS20850 -1.9 -0.8 resolvase compare
BBR_RS11770 -1.9 -3.6 chorismate mutase compare
BBR_RS19645 -1.9 -7.5 RNA degradosome polyphosphate kinase compare
BBR_RS20430 -1.8 -4.5 hypothetical protein compare
BBR_RS14240 -1.8 -5.3 1,4-alpha-glucan branching protein GlgB compare
BBR_RS16955 -1.8 -2.7 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH compare
BBR_RS19055 -1.8 -1.7 ferredoxin family protein compare
BBR_RS13840 -1.8 -3.3 DUF3043 domain-containing protein compare
BBR_RS14280 -1.8 -2.4 dephospho-CoA kinase compare
BBR_RS16965 -1.8 -1.2 ATP-dependent DNA helicase compare
BBR_RS16905 -1.8 -3.7 hypothetical protein compare
BBR_RS15805 -1.8 -4.6 prolipoprotein diacylglyceryl transferase compare
BBR_RS16540 -1.7 -3.0 XRE family transcriptional regulator compare
BBR_RS10910 -1.7 -9.6 molecular chaperone DnaJ compare
BBR_RS17515 -1.7 -5.2 hypothetical protein compare
BBR_RS20450 -1.7 -11.3 murein biosynthesis integral membrane protein MurJ compare
BBR_RS20455 -1.7 -6.6 thioredoxin-disulfide reductase compare
BBR_RS20460 -1.7 -3.6 chromosome partitioning protein ParB compare
BBR_RS16655 -1.7 -3.9 tyrosine recombinase XerC compare
BBR_RS12805 -1.7 -2.7 hypothetical protein compare
BBR_RS20525 -1.6 -5.5 DUF3800 domain-containing protein compare
BBR_RS19325 -1.6 -2.6 hypothetical protein compare
BBR_RS13215 -1.6 -1.3 hypothetical protein compare
BBR_RS17860 -1.6 -9.2 ABC transporter ATP-binding protein compare
BBR_RS18755 -1.6 -1.4 30S ribosome-binding factor RbfA compare
BBR_RS12710 -1.6 -3.1 hypothetical protein compare
BBR_RS17455 -1.5 -4.7 DNA-binding response regulator compare
BBR_RS12700 -1.5 -6.1 hypothetical protein compare
BBR_RS19445 -1.5 -11.7 glutamate 5-kinase compare
BBR_RS15755 -1.5 -1.8 hypothetical protein compare
BBR_RS15370 -1.5 -2.6 macro domain-containing protein compare
BBR_RS16150 -1.5 -4.9 GuaB3 family IMP dehydrogenase-related protein compare
BBR_RS15230 -1.5 -4.3 elongation factor 4 compare
BBR_RS10900 -1.5 -1.0 molecular chaperone DnaK compare
BBR_RS13510 -1.5 -4.8 LysR family transcriptional regulator compare
BBR_RS17895 -1.5 -5.4 TetR/AcrR family transcriptional regulator compare
BBR_RS12650 -1.5 -7.0 polysaccharide pyruvyl transferase family protein compare
BBR_RS19755 -1.5 -8.9 glycosyl transferase compare
BBR_RS14230 -1.5 -4.5 HAMP domain-containing histidine kinase compare
BBR_RS18565 -1.4 -1.1 CHAP domain-containing protein compare
BBR_RS17720 -1.4 -7.1 CRISPR-associated helicase/endonuclease Cas3 compare
BBR_RS16250 -1.4 -3.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB compare
BBR_RS13770 -1.4 -2.6 DNA repair protein RecO compare
BBR_RS17855 -1.4 -8.6 ABC transporter ATP-binding protein compare
BBR_RS19745 -1.4 -10.1 LTA synthase family protein compare
BBR_RS17865 -1.4 -3.3 MarR family transcriptional regulator compare
BBR_RS15355 -1.4 -2.0 DUF3800 domain-containing protein compare
BBR_RS12755 -1.4 -9.2 DUF4365 domain-containing protein compare
BBR_RS20795 -1.4 -1.3 cystathionine gamma-lyase compare
BBR_RS18375 -1.4 -6.3 ATP-dependent helicase compare
BBR_RS15375 -1.4 -4.4 phosphoesterase compare
BBR_RS18550 -1.3 -5.1 universal stress protein compare
BBR_RS16165 -1.3 -3.7 M23 family peptidase compare


Specific Phenotypes

For 1 genes in this experiment

For nutrient dropout no Biotin in Bifidobacterium breve UCC2003

For nutrient dropout no Biotin across organisms