Experiment set2IT033 for Shewanella loihica PV-4

Compare to:

LB with Thallium(I) acetate 10 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_3097 +4.8 30.7 TonB-dependent siderophore receptor (RefSeq) compare
Shew_3658 +3.2 15.4 hypothetical protein (RefSeq) compare
Shew_3841 +2.9 5.4 TonB-dependent siderophore receptor (RefSeq) compare
Shew_1796 +2.2 9.5 hypothetical protein (RefSeq) compare
Shew_0127 +2.2 5.2 LexA repressor (RefSeq) compare
Shew_1797 +2.2 2.9 paraquat-inducible protein A (RefSeq) compare
Shew_0468 +2.1 9.3 LysR family transcriptional regulator (RefSeq) compare
Shew_1458 +2.0 9.7 serine/threonine transporter SstT (RefSeq) compare
Shew_2950 +2.0 3.2 RluA family pseudouridine synthase (RefSeq) compare
Shew_1798 +1.9 6.1 paraquat-inducible protein A (RefSeq) compare
Shew_2481 +1.8 6.7 porin (RefSeq) compare
Shew_1852 +1.8 4.0 acriflavin resistance protein (RefSeq) compare
Shew_3311 +1.8 8.3 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_1851 +1.8 1.2 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_1186 +1.7 3.6 transcriptional regulator NrdR (RefSeq) compare
Shew_1397 +1.7 3.9 amino acid/peptide transporter (RefSeq) compare
Shew_0467 +1.7 5.3 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_3805 +1.7 3.9 rhodanese domain-containing protein (RefSeq) compare
Shew_2349 +1.6 7.6 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0939 +1.6 9.1 leucyl aminopeptidase (RefSeq) compare
Shew_2052 +1.6 5.2 TetR family transcriptional regulator (RefSeq) compare
Shew_1861 +1.6 4.3 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin (RefSeq) compare
Shew_3560 +1.6 4.9 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) compare
Shew_1673 fabG +1.5 1.2 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_2569 +1.5 4.4 MerR family transcriptional regulator (RefSeq) compare
Shew_0782 +1.5 4.1 DNA-binding transcriptional regulator AsnC (RefSeq) compare
Shew_2061 +1.5 1.7 radical SAM domain-containing protein (RefSeq) compare
Shew_3570 +1.5 6.9 two component transcriptional regulator (RefSeq) compare
Shew_R0076 +1.5 1.4 tRNA-Asn (RefSeq) compare
Shew_1731 +1.5 0.9 histidine triad (HIT) protein (RefSeq) compare
Shew_2327 +1.4 0.8 hypothetical protein (RefSeq) compare
Shew_2708 +1.4 3.1 Na(+)-translocating NADH-quinone reductase subunit B (RefSeq) compare
Shew_3638 envZ +1.4 8.3 osmolarity sensor protein (RefSeq) compare
Shew_0950 +1.4 4.6 DEAD/DEAH box helicase domain-containing protein (RefSeq) compare
Shew_2923 +1.4 7.3 tRNA-i(6)A37 thiotransferase enzyme MiaB (RefSeq) compare
Shew_2959 +1.4 2.3 LysR family transcriptional regulator (RefSeq) compare
Shew_1889 +1.4 6.5 alpha amylase, catalytic region (RefSeq) compare
Shew_3561 +1.3 7.1 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) compare
Shew_3637 ompR +1.3 6.1 osmolarity response regulator (RefSeq) compare
Shew_1995 +1.3 1.5 PP-loop domain-containing protein (RefSeq) compare
Shew_0462 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_0895 +1.2 6.2 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_0322 +1.2 4.2 diaminopimelate decarboxylase (RefSeq) compare
Shew_3657 +1.2 5.7 oligopeptidase A (RefSeq) compare
Shew_2646 +1.2 0.9 hypothetical protein (RefSeq) compare
Shew_2785 +1.2 0.9 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_2494 +1.2 2.0 phage shock protein C, PspC (RefSeq) compare
Shew_0343 +1.2 1.1 hypothetical protein (RefSeq) compare
Shew_3571 +1.2 7.2 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_2458 +1.1 0.9 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_1445 +1.1 0.8 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), small permease component (from data) compare
Shew_1518 +1.1 1.1 hypothetical protein (RefSeq) compare
Shew_1732 +1.1 2.0 hypothetical protein (RefSeq) compare
Shew_3295 +1.1 5.7 AFG1 family ATPase (RefSeq) compare
Shew_2919 +1.1 1.3 translation-associated GTPase (RefSeq) compare
Shew_1455 +1.1 0.9 dual specificity protein phosphatase (RefSeq) compare
Shew_0973 +1.1 2.9 extracellular solute-binding protein (RefSeq) compare
Shew_3122 +1.1 0.9 PepSY-associated TM helix domain-containing protein (RefSeq) compare
Shew_0390 +1.1 1.0 MSHA biogenesis protein MshM (RefSeq) compare
Shew_3513 +1.0 1.6 hypothetical protein (RefSeq) compare
Shew_2337 tgt +1.0 5.2 queuine tRNA-ribosyltransferase (RefSeq) compare
Shew_2258 +1.0 1.2 NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30 (RefSeq) compare
Shew_3684 +1.0 5.4 binding-protein-dependent transport systems inner membrane component (RefSeq) compare
Shew_1444 +1.0 2.1 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), large permease component (from data) compare
Shew_0450 +1.0 3.0 1-acyl-sn-glycerol-3-phosphate acyltransferase (RefSeq) compare
Shew_2403 +1.0 1.2 arylesterase (RefSeq) compare
Shew_1387 +1.0 1.2 chemotaxis-specific methylesterase (RefSeq) compare
Shew_2188 +1.0 4.2 long-chain-fatty-acid--CoA ligase (RefSeq) compare
Shew_2436 +1.0 3.4 membrane protein involved in aromatic hydrocarbon degradation (RefSeq) compare
Shew_1488 +1.0 1.5 FAD linked oxidase domain-containing protein (RefSeq) compare
Shew_1278 +1.0 0.6 hypothetical protein (RefSeq) compare
Shew_0410 +1.0 4.4 peptidase U62, modulator of DNA gyrase (RefSeq) compare
Shew_3247 +1.0 0.8 hypothetical protein (RefSeq) compare
Shew_1896 +1.0 0.9 putative lipoprotein (RefSeq) compare
Shew_1052 +1.0 2.8 GTP-binding protein LepA (RefSeq) compare
Shew_3718 +0.9 1.1 hypothetical protein (RefSeq) compare
Shew_3617 +0.9 1.0 general secretion pathway protein F (RefSeq) compare
Shew_0396 +0.9 0.9 methylation site containing protein (RefSeq) compare
Shew_2654 queF +0.9 2.3 7-cyano-7-deazaguanine reductase (RefSeq) compare
Shew_1050 +0.9 2.2 sigma E regulatory protein, MucB/RseB (RefSeq) compare
Shew_3509 +0.9 2.4 hypothetical protein (RefSeq) compare
Shew_2434 +0.9 1.8 hypothetical protein (RefSeq) compare
Shew_2459 +0.9 0.8 hypothetical protein (RefSeq) compare
Shew_2582 +0.9 2.6 Na+/H+ antiporter NhaC (RefSeq) compare
Shew_3135 +0.9 3.2 L-lactate permease (RefSeq) compare
Shew_0718 +0.9 2.4 cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) compare
Shew_2768 +0.9 1.7 flagellar motor protein PomA (RefSeq) compare
Shew_1782 +0.9 5.0 MarR family transcriptional regulator (RefSeq) compare
Shew_0860 +0.9 0.8 hypothetical protein (RefSeq) compare
Shew_2043 +0.9 1.2 cation diffusion facilitator family transporter (RefSeq) compare
Shew_1092 +0.9 2.3 amino acid carrier protein (RefSeq) compare
Shew_2185 +0.9 3.2 septum site-determining protein MinD (RefSeq) compare
Shew_0057 +0.9 2.2 cytoplasmic chaperone TorD family protein (RefSeq) compare
Shew_0857 +0.9 2.1 hypothetical protein (RefSeq) compare
Shew_3522 +0.8 0.9 hypothetical protein (RefSeq) compare
Shew_1432 +0.8 1.0 ferredoxin-type protein NapF (RefSeq) compare
Shew_1686 +0.8 1.4 hypothetical protein (RefSeq) compare
Shew_0833 +0.8 0.8 hypoxanthine-guanine phosphoribosyltransferase (RefSeq) compare
Shew_3621 +0.8 3.8 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_3204 +0.8 1.6 cytochrome B561 (RefSeq) compare
Shew_1080 +0.8 1.4 homoserine kinase (RefSeq) compare
Shew_3080 +0.8 1.9 thiol:disulfide interchange protein, putative (RefSeq) compare
Shew_2199 +0.8 1.8 histidinol-phosphate aminotransferase (RefSeq) compare
Shew_2766 +0.8 1.8 thiamine biosynthesis protein ThiI (RefSeq) compare
Shew_3595 +0.8 2.8 hypothetical protein (RefSeq) compare
Shew_1669 +0.8 3.3 butyryl-CoA dehydrogenase (RefSeq) compare
Shew_2074 +0.8 2.7 TonB-dependent receptor (RefSeq) compare
Shew_2483 dinG +0.8 5.4 ATP-dependent DNA helicase DinG (RefSeq) compare
Shew_1473 +0.8 2.2 hypothetical protein (RefSeq) compare
Shew_1231 +0.8 0.8 ECF subfamily RNA polymerase sigma-24 factor (RefSeq) compare
Shew_2105 +0.8 0.7 methylated-DNA-(protein)-cysteine S-methyltransferase (RefSeq) compare
Shew_0027 +0.8 2.0 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_3622 hslO +0.8 3.7 Hsp33-like chaperonin (RefSeq) compare
Shew_2544 +0.8 1.3 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) compare
Shew_1591 +0.8 1.0 bifunctional methionine sulfoxide reductase B/A protein (RefSeq) compare
Shew_2416 +0.8 1.0 chorismate synthase (RefSeq) compare
Shew_3164 +0.8 1.8 ABC transporter-related protein (RefSeq) compare
Shew_1411 +0.8 5.9 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_2386 +0.8 2.6 hypothetical protein (RefSeq) compare
Shew_1933 +0.7 0.9 endonuclease/exonuclease/phosphatase (RefSeq) compare
Shew_2241 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_0084 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_2395 +0.7 1.2 hypothetical protein (RefSeq) compare
Shew_2228 +0.7 4.2 inosine kinase (RefSeq) compare
Shew_2652 +0.7 1.9 hypothetical protein (RefSeq) compare
Shew_2189 +0.7 2.0 alpha/beta hydrolase fold (RefSeq) compare
Shew_0687 +0.7 2.7 heat shock protein DnaJ domain-containing protein (RefSeq) compare
Shew_0802 +0.7 2.7 chromate transporter (RefSeq) compare
Shew_3853 +0.7 4.4 parB-like partition protein (RefSeq) compare
Shew_0218 +0.7 3.2 hypothetical protein (RefSeq) compare
Shew_1583 yebU +0.7 2.1 rRNA (cytosine-C(5)-)-methyltransferase RsmF (RefSeq) compare
Shew_0932 +0.7 0.9 radical SAM domain-containing protein (RefSeq) compare
Shew_2407 +0.7 1.9 putative periplasmic protease (RefSeq) compare
Shew_2132 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_1741 +0.7 1.7 beta-lactamase domain-containing protein (RefSeq) compare
Shew_2589 +0.7 0.7 hypothetical protein (RefSeq) compare
Shew_0136 +0.7 3.4 stearoyl-CoA 9-desaturase (RefSeq) compare
Shew_3265 +0.7 0.9 CutA1 divalent ion tolerance protein (RefSeq) compare
Shew_1677 +0.7 1.8 leucyl aminopeptidase (RefSeq) compare
Shew_1287 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_1665 +0.7 0.8 peptidase S51, dipeptidase E (RefSeq) compare
Shew_2448 nrdG +0.7 1.8 anaerobic ribonucleotide reductase-activating protein (RefSeq) compare
Shew_0537 +0.7 0.7 hypothetical protein (RefSeq) compare
Shew_3069 +0.7 0.7 5-formyltetrahydrofolate cyclo-ligase (RefSeq) compare
Shew_1173 +0.7 1.3 hypothetical protein (RefSeq) compare
Shew_3328 +0.7 2.2 Ig domain-containing protein (RefSeq) compare
Shew_3525 fabG +0.7 2.2 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_1023 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_0406 +0.7 1.8 maf protein (RefSeq) compare
Shew_3854 +0.7 2.5 cobyrinic acid a,c-diamide synthase (RefSeq) compare
Shew_1828 +0.7 2.7 peptidoglycan binding domain-containing protein (RefSeq) compare
Shew_2213 +0.7 1.5 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (RefSeq) compare
Shew_2892 +0.7 1.9 major facilitator transporter (RefSeq) compare
Shew_1668 +0.7 3.3 methylmalonate-semialdehyde dehydrogenase (RefSeq) compare
Shew_1891 +0.7 0.8 Fmu (Sun) domain-containing protein (RefSeq) compare
Shew_1568 +0.7 2.0 arginyl-tRNA-protein transferase (RefSeq) compare
Shew_2637 +0.6 1.1 PII uridylyl-transferase (RefSeq) compare
Shew_3230 +0.6 4.1 rRNA (guanine-N(2)-)-methyltransferase (RefSeq) compare
Shew_0108 +0.6 4.4 polysaccharide deacetylase (RefSeq) compare
Shew_2903 +0.6 1.4 hypothetical protein (RefSeq) compare
Shew_0722 +0.6 0.5 hypothetical protein (RefSeq) compare
Shew_1428 +0.6 1.0 fructokinase (RefSeq) compare
Shew_1514 upp +0.6 1.6 uracil phosphoribosyltransferase (RefSeq) compare
Shew_0898 +0.6 1.4 MltA-interacting MipA family protein (RefSeq) compare
Shew_0121 +0.6 0.6 hypothetical protein (RefSeq) compare
Shew_3515 +0.6 2.8 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_2053 +0.6 2.2 peptidyl-dipeptidase A (RefSeq) compare
Shew_2417 +0.6 2.0 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase (RefSeq) compare
Shew_2423 +0.6 1.3 hypothetical protein (RefSeq) compare
Shew_0466 +0.6 3.1 acriflavin resistance protein (RefSeq) compare
Shew_3495 +0.6 0.9 hypothetical protein (RefSeq) compare
Shew_1071 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_1630 +0.6 1.7 transcription-repair coupling factor (RefSeq) compare
Shew_1194 +0.6 1.4 glutathione-dependent formaldehyde-activating, GFA (RefSeq) compare
Shew_1812 +0.6 2.6 23S rRNA m(2)G2445 methyltransferase (RefSeq) compare
Shew_1511 +0.6 1.1 UMP phosphatase (RefSeq) compare
Shew_1423 +0.6 0.7 sulfate adenylyltransferase, large subunit (RefSeq) compare
Shew_0196 +0.6 1.6 redoxin domain-containing protein (RefSeq) compare
Shew_2202 +0.6 0.5 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq) compare
Shew_3733 +0.6 2.9 hypothetical protein (RefSeq) compare
Shew_1968 +0.6 0.7 beta-lactamase (RefSeq) compare
Shew_1265 +0.6 0.9 hypothetical protein (RefSeq) compare
Shew_2783 +0.6 3.7 peptidase U32 (RefSeq) compare
Shew_1202 +0.6 2.7 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_0434 +0.6 1.5 hypothetical protein (RefSeq) compare
Shew_3683 +0.6 2.2 extracellular solute-binding protein (RefSeq) compare
Shew_1039 +0.6 3.1 phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq) compare
Shew_1960 +0.6 0.5 hypothetical protein (RefSeq) compare
Shew_1570 +0.6 1.7 17 kDa surface antigen (RefSeq) compare
Shew_2884 +0.6 1.0 glycine cleavage system regulatory protein-like protein (RefSeq) compare
Shew_0930 +0.6 0.7 AMMECR1 domain-containing protein (RefSeq) compare
Shew_3855 gidB +0.6 2.1 glucose-inhibited division protein B (RefSeq) compare
Shew_3099 +0.6 0.7 TetR family transcriptional regulator (RefSeq) compare
Shew_2210 +0.6 2.1 proprotein convertase, P (RefSeq) compare
Shew_2148 +0.6 1.1 hypothetical protein (RefSeq) compare
Shew_3487 pyrE +0.6 2.2 orotate phosphoribosyltransferase (RefSeq) compare
Shew_0972 +0.6 2.6 glutamate--ammonia ligase (RefSeq) compare
Shew_2287 +0.6 1.0 galactokinase (RefSeq) compare
Shew_0414 +0.6 2.5 ABC-2 type transporter (RefSeq) compare
Shew_1776 +0.6 2.2 acetolactate synthase 3 catalytic subunit (RefSeq) compare


Specific Phenotypes

For 12 genes in this experiment

For stress Thallium(I) acetate in Shewanella loihica PV-4

For stress Thallium(I) acetate across organisms