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Experiment set2IT033 for
Methanococcus maripaludis S2
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Formate McCas, 2.5g/L bicarb, 200 mM MOPs, 20 psi N2CO2, SO4 FREE
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS06700
-9.0
-12.4
hypothetical protein
compare
MMP
_RS06685
-8.8
-12.1
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS06355
-8.6
-3.4
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS05515
-8.4
-6.9
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06345
-8.0
-12.1
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS06680
-7.7
-17.1
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS06715
-7.5
-20.9
cache domain-containing protein
compare
MMP
_RS06350
-7.2
-7.2
HesA/MoeB/ThiF family protein
compare
MMP
_RS01985
-7.1
-6.3
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS02195
-6.9
-5.6
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS01500
-6.7
-3.5
CBS domain-containing protein
compare
MMP
_RS06720
-6.7
-8.4
response regulator transcription factor
compare
MMP
_RS03015
-6.7
-10.2
GTP 3' 8-cyclase MoaA
compare
MMP
_RS01175
-6.4
-5.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS06705
-6.3
-9.3
formate/nitrite transporter family protein
compare
MMP
_RS06400
-6.1
-2.4
4Fe-4S binding protein
compare
MMP
_RS01020
-6.1
-1.4
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS06285
-6.0
-3.6
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS06475
-5.8
-7.9
FAD-dependent oxidoreductase
compare
MMP
_RS00895
-5.7
-5.6
hypothetical protein
compare
MMP
_RS06295
-5.7
-10.4
methanogenesis marker 14 protein
compare
MMP
_RS06625
-5.6
-3.7
DNA primase
compare
MMP
_RS03035
-5.4
-7.1
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS00305
-5.4
-2.8
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS08300
-5.3
-2.1
metal-sulfur cluster assembly factor
compare
MMP
_RS01795
-5.2
-2.5
methanogenesis marker 6 protein
compare
MMP
_RS08460
-5.2
-3.9
proteasome-activating nucleotidase
compare
MMP
_RS03025
-5.2
-9.6
molybdenum cofactor guanylyltransferase
compare
MMP
_RS05920
-5.0
-1.2
50S ribosomal protein L37e
compare
MMP
_RS07730
-4.9
-3.2
pyruvate synthase subunit beta
compare
MMP
_RS07635
-4.9
-10.1
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS01220
-4.9
-10.3
hypothetical protein
compare
MMP
_RS04585
-4.9
-12.8
AIR synthase related protein
compare
MMP
_RS03400
-4.8
-4.2
archease
compare
MMP
_RS03640
-4.8
-5.7
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS08820
-4.8
-7.7
hypothetical protein
compare
MMP
_RS08105
-4.8
-8.7
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS06370
-4.8
-7.2
biotin synthase BioB
compare
MMP
_RS08095
-4.8
-8.9
dethiobiotin synthase
compare
MMP
_RS03600
-4.8
-3.7
triose-phosphate isomerase
compare
MMP
_RS03315
-4.8
-1.8
ferrous iron transport protein A
compare
MMP
_RS01005
-4.8
-1.5
riboflavin synthase
compare
MMP
_RS01225
-4.7
-6.6
DUF5379 domain-containing protein
compare
MMP
_RS07645
-4.7
-8.0
aldehyde dehydrogenase family protein
compare
MMP
_RS04685
-4.7
-5.4
DUF126 domain-containing protein
compare
MMP
_RS04500
-4.7
-19.4
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS09020
-4.6
-2.4
hypothetical protein
compare
MMP
_RS08100
-4.6
-9.3
8-amino-7-oxononanoate synthase
compare
MMP
_RS04775
-4.5
-5.7
adenosylhomocysteinase
compare
MMP
_RS06270
-4.4
-8.1
TIGR00300 family protein
compare
MMP
_RS06120
-4.4
-2.9
UPF0147 family protein
compare
MMP
_RS08720
-4.4
-2.6
4Fe-4S binding protein
compare
MMP
_RS01610
-4.4
-4.7
hypothetical protein
compare
MMP
_RS07600
-4.4
-3.5
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS02280
-4.4
-1.4
DUF211 domain-containing protein
compare
MMP
_RS00110
-4.4
-5.2
hypothetical protein
compare
MMP
_RS06200
-4.3
-11.0
M24 family metallopeptidase
compare
MMP
_RS08635
-4.3
-3.3
UbiA family prenyltransferase
compare
MMP
_RS07580
-4.2
-4.8
DUF356 domain-containing protein
compare
MMP
_RS03435
-4.2
-3.0
ketol-acid reductoisomerase
compare
MMP
_RS07845
-4.2
-3.5
LL-diaminopimelate aminotransferase
compare
MMP
_RS03960
-4.1
-1.6
hypothetical protein
compare
MMP
_RS04780
-4.1
-4.8
ribonuclease P
compare
MMP
_RS01755
-4.1
-2.3
DUF2097 domain-containing protein
compare
MMP
_RS02900
-4.1
-0.9
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS00300
-4.1
-1.3
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS06730
-4.0
-3.0
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS08745
-4.0
-9.4
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS06340
-4.0
-10.6
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS02010
-4.0
-8.0
PHP domain-containing protein
compare
MMP
_RS04890
-4.0
-1.3
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS06885
-3.9
-3.9
50S ribosome-binding GTPase
compare
MMP
_RS06230
-3.9
-4.7
helix-turn-helix domain-containing protein
compare
MMP
_RS01800
-3.9
-7.0
TIGR00303 family protein
compare
MMP
_RS07005
-3.9
-1.3
4Fe-4S binding protein
compare
MMP
_RS07195
-3.8
-14.5
M20 family metallo-hydrolase
compare
MMP
_RS08790
-3.8
-3.9
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS08210
-3.8
-3.6
phosphatidylglycerophosphatase A
compare
MMP
_RS05345
-3.8
-11.5
hypothetical protein
compare
MMP
_RS07750
-3.8
-6.5
DUF357 domain-containing protein
compare
MMP
_RS02875
-3.7
-12.0
chorismate pyruvate-lyase family protein
compare
MMP
_RS06925
-3.7
-4.6
ribonuclease VapC4
compare
MMP
_RS06895
-3.7
-3.0
selenocysteine-specific translation elongation factor
compare
MMP
_RS05875
-3.6
-9.0
hydroxyethylthiazole kinase
compare
MMP
_RS00685
-3.6
-6.6
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS06315
-3.6
-1.6
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS07545
-3.6
-1.6
HTH domain-containing protein
compare
MMP
_RS08715
-3.6
-2.7
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS00130
-3.5
-1.6
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS07755
-3.5
-1.9
DUF555 domain-containing protein
compare
MMP
_RS03580
-3.5
-4.7
signal recognition particle-docking protein FtsY
compare
MMP
_RS03205
-3.4
-1.8
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS02190
-3.4
-4.8
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS02135
-3.4
-6.1
DUF5612 domain-containing protein
compare
MMP
_RS02345
-3.4
-5.4
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS02800
-3.4
-8.5
nucleotidyltransferase domain-containing protein
compare
MMP
_RS00115
-3.4
-16.3
radical SAM protein
compare
MMP
_RS07445
-3.4
-4.4
helix-turn-helix domain-containing protein
compare
MMP
_RS01250
-3.4
-6.6
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS01385
-3.3
-1.1
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS05815
-3.3
-4.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS05250
-3.2
-2.4
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS05545
-3.2
-9.6
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS05845
-3.2
-2.4
tRNA-intron lyase
compare
MMP
_RS03155
-3.2
-10.2
precorrin-6A reductase
compare
MMP
_RS07630
-3.1
-1.8
ATP-binding cassette domain-containing protein
compare
MMP
_RS07380
-3.1
-3.4
transcription elongation factor Spt5
compare
MMP
_RS01380
-3.1
-5.3
PHP domain-containing protein
compare
MMP
_RS02355
-3.1
-3.7
30S ribosomal protein S27ae
compare
MMP
_RS08435
-3.0
-3.9
Era-like GTP-binding protein
compare
MMP
_RS02165
-3.0
-11.1
tRNA-dihydrouridine synthase
compare
MMP
_RS02235
-2.9
-15.0
CBS domain-containing protein
compare
MMP
_RS06020
-2.9
-5.9
archaeoflavoprotein AfpA
compare
MMP
_RS02240
-2.9
-4.5
methanogenesis marker 7 protein
compare
MMP
_RS03475
-2.9
-1.1
hypothetical protein
compare
MMP
_RS06215
-2.8
-4.9
30S ribosomal protein S6e
compare
MMP
_RS07735
-2.8
-1.3
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS07605
-2.8
-5.9
diadenylate cyclase
compare
MMP
_RS01830
-2.8
-2.3
tRNA-Val
compare
MMP
_RS06105
-2.8
-13.0
hydrogenase maturation peptidase HycI
compare
MMP
_RS06630
-2.8
-1.8
UPF0058 family protein
compare
MMP
_RS04870
-2.8
-4.8
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS05555
-2.8
-1.9
DUF4040 domain-containing protein
compare
MMP
_RS05930
-2.7
-3.3
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS07200
-2.7
-6.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS04605
-2.6
-2.9
cobalt ECF transporter T component CbiQ
compare
MMP
_RS08440
-2.6
-3.9
cell division protein SepF
compare
MMP
_RS08445
-2.6
-6.1
DUF2099 family protein
compare
MMP
_RS03095
-2.5
-10.0
diphthine synthase
compare
MMP
_RS07575
-2.5
-3.6
RNA ligase partner protein
compare
MMP
_RS08650
-2.5
-4.5
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS04710
-2.5
-2.3
hypothetical protein
compare
MMP
_RS05550
-2.4
-1.1
cation:proton antiporter
compare
MMP
_RS00810
-2.4
-8.9
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS03110
-2.4
-8.4
glycosyltransferase family 2 protein
compare
MMP
_RS01725
-2.4
-5.4
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS07425
-2.4
-6.8
GTP-binding protein
compare
MMP
_RS01700
-2.3
-1.1
dihydroxy-acid dehydratase
compare
MMP
_RS08320
-2.3
-7.6
molybdopterin molybdotransferase MoeA
compare
MMP
_RS01365
-2.3
-2.3
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS07525
-2.3
-7.6
4Fe-4S binding protein
compare
MMP
_RS03140
-2.2
-12.4
hypothetical protein
compare
MMP
_RS05425
-2.1
-5.1
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS03145
-2.1
-9.0
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS05430
-2.1
-4.2
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS04615
-2.1
-2.9
PDGLE domain-containing protein
compare
MMP
_RS00320
-2.1
-2.3
class I SAM-dependent methyltransferase
compare
MMP
_RS05265
-2.1
-3.0
2-isopropylmalate synthase
compare
MMP
_RS00050
-2.1
-8.6
AarF/UbiB family protein
compare
MMP
_RS05445
-2.1
-11.5
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS01840
-2.1
-10.8
TIGR00289 family protein
compare
MMP
_RS01325
-2.1
-3.1
dihydroneopterin aldolase family protein
compare
MMP
_RS00750
-2.1
-3.0
fumarate hydratase
compare
MMP
_RS04875
-2.0
-5.2
energy-converting hydrogenase B subunit P
compare
MMP
_RS08330
-2.0
-6.9
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS03445
-2.0
-1.6
methanogenesis marker 17 protein
compare
MMP
_RS02885
-2.0
-13.2
molybdopterin biosynthesis protein
compare
MMP
_RS00900
-2.0
-3.2
50S ribosomal protein L39e
compare
MMP
_RS05540
-1.9
-2.7
hypothetical protein
compare
MMP
_RS02245
-1.9
-3.2
hypothetical protein
compare
MMP
_RS02340
-1.9
-2.6
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS01265
-1.9
-2.5
hypothetical protein
compare
MMP
_RS07090
-1.9
-8.2
tRNA (adenine-N1)-methyltransferase
compare
MMP
_RS06940
-1.9
-4.2
polyprenyl diphosphate synthase
compare
MMP
_RS07555
-1.9
-0.9
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS00985
-1.9
-5.7
CDC48 family AAA ATPase
compare
MMP
_RS07435
-1.8
-2.7
GMP synthase subunit A
compare
MMP
_RS03700
-1.8
-8.0
sodium:proton antiporter
compare
MMP
_RS05440
-1.7
-8.3
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS01545
-1.7
-1.4
CBS domain-containing protein
compare
MMP
_RS07420
-1.7
-4.1
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS01600
-1.7
-2.9
50S ribosomal protein L15e
compare
MMP
_RS01475
-1.7
-9.7
phosphosulfolactate synthase
compare
MMP
_RS08355
-1.7
-5.8
Na(+)/H(+) antiporter subunit B
compare
MMP
_RS07955
-1.7
-5.3
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS00120
-1.7
-4.8
LysR family transcriptional regulator
compare
MMP
_RS08645
-1.6
-7.3
UPF0179 family protein
compare
MMP
_RS05925
-1.6
-5.2
small nuclear ribonucleoprotein
compare
MMP
_RS05450
-1.6
-3.2
CoB--CoM heterodisulfide reductase subunit C
compare
MMP
_RS08370
-1.6
-0.8
cation:proton antiporter subunit C
compare
MMP
_RS07190
-1.6
-8.7
chromosome segregation protein SMC
compare
MMP
_RS06110
-1.6
-2.8
ATP-dependent protease LonB
compare
MMP
_RS06840
-1.5
-1.0
DNA-directed RNA polymerase subunit N
compare
MMP
_RS06130
-1.5
-3.5
peptidylprolyl isomerase
compare
MMP
_RS03555
-1.5
-6.9
transcriptional regulator
compare
MMP
_RS01180
-1.5
-1.6
XTP/dITP diphosphatase
compare
MMP
_RS05525
-1.5
-7.6
calcium/sodium antiporter
compare
MMP
_RS05245
-1.5
-9.7
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS01335
-1.5
-2.7
prefoldin subunit beta
compare
MMP
_RS03305
-1.5
-8.3
winged helix-turn-helix domain-containing protein
compare
MMP
_RS07685
-1.5
-6.3
TIGR01212 family radical SAM protein
compare
MMP
_RS04620
-1.5
-4.6
cobalt transporter CbiM
compare
MMP
_RS01665
-1.5
-2.5
DUF2111 domain-containing protein
compare
MMP
_RS07390
-1.5
-3.0
cell division protein FtsZ
compare
MMP
_RS01045
-1.5
-6.3
diphthamide biosynthesis enzyme Dph2
compare
MMP
_RS00720
-1.4
-9.5
metal-dependent hydrolase
compare
MMP
_RS02170
-1.4
-4.9
CBS domain-containing protein
compare
MMP
_RS05420
-1.4
-3.3
DUF61 family protein
compare
MMP
_RS05765
-1.4
-4.3
M42 family metallopeptidase
compare
MMP
_RS00325
-1.4
-1.7
RNA-binding protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in rich t2 experiments