Experiment set2IT027 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Phenylalanine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3782 -6.3 -4.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3839 -6.0 -5.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_77 -5.9 -5.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4597 -5.7 -11.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4071 -5.7 -6.7 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4047 -5.6 -5.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3842 -5.6 -6.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2630 -5.5 -8.4 Phenylalanine 4-monooxygenase (EC 1.14.16.1) (from data) conserved
Pf6N2E2_5176 -5.4 -11.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -5.3 -11.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -5.3 -11.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3253 -5.2 -7.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_71 -5.2 -8.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5175 -5.0 -18.6 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_5014 -5.0 -2.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3630 -5.0 -9.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4564 -4.9 -11.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4826 -4.8 -9.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_2629 -4.7 -12.4 Phenylalanine hydroxylase transcriptional activator PhhR conserved
Pf6N2E2_3783 -4.7 -7.0 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4048 -4.6 -8.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2258 -4.6 -13.5 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5177 -4.6 -12.5 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3252 -4.5 -10.5 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_64 -4.5 -4.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5006 -4.5 -11.7 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3610 -4.4 -6.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_456 -4.4 -13.5 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (from data) conserved
Pf6N2E2_4279 -4.3 -16.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4372 -4.2 -7.0 FIG00460773: hypothetical protein compare
Pf6N2E2_5290 -4.2 -12.0 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) conserved
Pf6N2E2_5292 -4.2 -7.9 Maleylacetoacetate isomerase (EC 5.2.1.2) (from data) conserved
Pf6N2E2_2217 -4.2 -7.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5291 -4.1 -20.5 Fumarylacetoacetase (EC 3.7.1.2) compare
Pf6N2E2_4752 -4.0 -14.2 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_5178 -4.0 -2.7 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3932 -4.0 -6.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5527 -4.0 -5.3 Cold shock protein CspC compare
Pf6N2E2_5156 -3.8 -3.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5723 -3.8 -14.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_66 -3.7 -8.4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4278 -3.7 -13.9 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2073 -3.6 -10.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3940 -3.5 -11.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3251 -3.5 -13.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2632 -3.3 -7.5 tyrosine aminotransferase (EC 2.6.1.57) (from data) conserved
Pf6N2E2_3841 -3.2 -8.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3248 -3.2 -5.7 Probable transmembrane protein compare
Pf6N2E2_4638 -3.2 -5.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2277 -3.1 -4.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_1381 -3.1 -10.9 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_63 -2.9 -5.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3170 -2.9 -7.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2074 -2.8 -2.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4453 -2.7 -16.5 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_2588 -2.5 -3.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4353 -2.5 -7.4 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_2218 -2.5 -6.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_1056 -2.5 -1.5 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4277 -2.4 -8.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_302 -2.4 -7.9 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5579 -2.3 -6.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4803 -2.3 -2.3 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4759 -2.3 -14.1 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3984 -2.1 -10.3 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4599 -2.1 -5.0 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4773 -2.1 -1.9 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_2753 -2.1 -5.1 HtrA protease/chaperone protein compare
Pf6N2E2_4464 -2.1 -4.5 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_5242 -2.1 -2.7 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2574 -2.0 -3.1 Flagellar synthesis regulator FleN compare
Pf6N2E2_4824 -2.0 -5.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_3762 -1.9 -7.8 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_2465 -1.8 -6.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5261 -1.8 -1.8 FIG00956983: hypothetical protein compare
Pf6N2E2_5160 -1.7 -1.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_1396 -1.7 -3.6 ABC transporter, ATP-binding protein compare
Pf6N2E2_4009 -1.6 -9.3 GGDEF domain protein compare
Pf6N2E2_5659 -1.6 -13.8 Acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
Pf6N2E2_3460 -1.6 -2.5 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2112 -1.6 -5.6 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit B (from data) conserved
Pf6N2E2_5155 -1.5 -3.4 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_4206 -1.5 -2.0 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2274 -1.5 -5.0 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3349 -1.5 -3.7 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_6099 -1.5 -2.1 tRNA-Glu-TTC compare
Pf6N2E2_3885 -1.5 -2.9 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2166 -1.4 -7.8 protein of unknown function DUF6, transmembrane compare
Pf6N2E2_4351 -1.4 -9.8 Predicted signal transduction protein compare
Pf6N2E2_3933 -1.4 -7.1 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_3062 -1.4 -4.4 Membrane-associated zinc metalloprotease compare
Pf6N2E2_3899 -1.4 -7.9 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_477 -1.4 -5.4 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
Pf6N2E2_4414 -1.4 -3.0 FIG00953808: hypothetical protein compare
Pf6N2E2_434 -1.4 -2.4 hypothetical protein compare
Pf6N2E2_3346 -1.3 -4.9 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_3665 -1.3 -1.4 serine/threonine protein kinase compare
Pf6N2E2_1379 -1.3 -5.5 Sensory box histidine kinase/response regulator compare
Pf6N2E2_2189 -1.3 -4.8 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_1705 -1.3 -2.1 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_424 -1.3 -5.9 Decarboxylase family protein compare
Pf6N2E2_1395 -1.3 -5.1 Uncharacterized conserved protein compare
Pf6N2E2_1932 -1.3 -5.1 Transcriptional regulator, IclR family compare
Pf6N2E2_3261 -1.3 -3.5 hypothetical protein compare
Pf6N2E2_1397 -1.3 -8.5 ABC transporter permease protein compare
Pf6N2E2_4360 -1.3 -8.7 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_4417 -1.3 -3.6 Protein of unknown function DUF484 compare
Pf6N2E2_4776 -1.2 -9.0 Coenzyme PQQ synthesis protein F compare
Pf6N2E2_2186 -1.2 -4.8 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5955 -1.2 -3.5 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_510 -1.2 -7.3 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_5536 -1.2 -1.4 Holliday junction DNA helicase RuvA compare
Pf6N2E2_2080 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_3725 -1.2 -2.8 FIG085779: Lipoprotein compare
Pf6N2E2_3938 -1.2 -8.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3461 -1.1 -1.7 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_81 -1.1 -3.4 hypothetical protein compare
Pf6N2E2_446 -1.1 -6.7 Glutathione reductase (EC 1.8.1.7) compare
Pf6N2E2_1387 -1.1 -5.6 Cytochrome C550 (Soluble cytochrome C) compare
Pf6N2E2_279 -1.1 -6.6 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_4579 -1.1 -1.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_4416 -1.1 -2.1 Tyrosine recombinase XerC compare
Pf6N2E2_4059 -1.1 -1.4 DNA-binding protein HU-alpha compare
Pf6N2E2_4204 -1.1 -1.8 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_309 -1.1 -1.8 FIG00957702: hypothetical protein compare
Pf6N2E2_5328 -1.1 -3.1 FIG00958649: hypothetical protein compare
Pf6N2E2_1400 -1.1 -6.9 Sensory box histidine kinase/response regulator compare
Pf6N2E2_4797 -1.0 -1.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_440 -1.0 -2.6 FIG00954920: hypothetical protein compare
Pf6N2E2_3300 -1.0 -2.9 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_1402 -1.0 -5.6 hypothetical protein compare
Pf6N2E2_2453 -1.0 -5.8 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase II (EC 2.5.1.54) conserved
Pf6N2E2_1386 -1.0 -4.3 amino acid ABC transporter, periplasmic substrate-binding protein compare
Pf6N2E2_1394 -1.0 -4.2 FIG00953323: hypothetical protein compare
Pf6N2E2_3807 -1.0 -2.1 Histidine utilization repressor compare
Pf6N2E2_4459 -1.0 -1.8 Transcriptional regulator, GntR family compare
Pf6N2E2_4352 -1.0 -2.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4342 -0.9 -2.8 Protein phosphatase ImpM compare
Pf6N2E2_2167 -0.9 -4.9 hypothetical protein compare
Pf6N2E2_469 -0.9 -1.3 lipoprotein, putative compare
Pf6N2E2_2675 -0.9 -1.3 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_5084 -0.9 -5.5 Glutathione-regulated potassium-efflux system ATP-binding protein compare
Pf6N2E2_3786 -0.9 -3.2 Twin-arginine translocation protein TatC compare
Pf6N2E2_5150 -0.9 -4.4 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2314 -0.9 -2.2 VapB protein (antitoxin to VapC) compare
Pf6N2E2_1382 -0.9 -6.4 Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.99.8) compare
Pf6N2E2_5001 -0.9 -1.5 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_178 -0.9 -1.1 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_280 -0.9 -3.2 hypothetical protein compare
Pf6N2E2_5524 -0.9 -6.8 Outer membrane porin, OprD family compare
Pf6N2E2_2986 -0.9 -2.5 Transcriptional regulator, LuxR family compare
Pf6N2E2_2292 -0.9 -2.9 Universal stress protein family COG0589 compare
Pf6N2E2_5153 -0.9 -3.8 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_1545 -0.9 -3.5 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_4150 -0.9 -3.6 probable exported protein YPO0432 compare
Pf6N2E2_5679 -0.9 -3.2 hypothetical protein compare
Pf6N2E2_5338 -0.9 -4.5 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_2340 -0.8 -3.1 Transcriptional regulator, GntR family compare
Pf6N2E2_4772 -0.8 -5.2 Coenzyme PQQ synthesis protein E compare
Pf6N2E2_493 -0.8 -3.4 YD repeat protein compare
Pf6N2E2_5342 -0.8 -2.7 21 kDa hemolysin precursor compare
Pf6N2E2_2756 -0.8 -4.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_4817 -0.8 -7.1 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_863 -0.8 -4.9 Transcriptional regulator, IclR family compare
Pf6N2E2_3607 -0.8 -4.1 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2010 -0.8 -1.3 hypothetical protein compare
Pf6N2E2_84 -0.8 -1.2 hypothetical protein compare
Pf6N2E2_5553 -0.8 -5.2 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5219 -0.8 -4.5 FIG140336: TPR domain protein compare
Pf6N2E2_1632 -0.8 -3.5 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) compare
Pf6N2E2_1676 -0.8 -1.1 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_2693 -0.8 -1.5 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2152 -0.8 -1.5 hypothetical protein compare
Pf6N2E2_1287 -0.8 -2.9 Mobile element protein compare
Pf6N2E2_2518 -0.8 -1.2 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_5722 -0.8 -2.3 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_5420 -0.8 -4.2 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
Pf6N2E2_3264 -0.8 -1.5 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_5430 -0.8 -4.6 Transglycosylase, Slt family compare
Pf6N2E2_3060 -0.8 -2.6 Outer membrane protein H precursor compare
Pf6N2E2_579 -0.8 -1.5 FIG00962753: hypothetical protein compare
Pf6N2E2_3257 -0.8 -2.3 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_1399 -0.8 -2.5 Transcriptional regulator, LuxR family compare
Pf6N2E2_2325 -0.8 -3.9 Recombination protein RecR compare
Pf6N2E2_48 -0.8 -2.7 FIG00955661: hypothetical protein compare
Pf6N2E2_5520 -0.8 -3.8 Sensory box histidine kinase compare
Pf6N2E2_4273 -0.8 -5.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_4818 -0.8 -3.8 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_75 -0.8 -2.7 Colicin V production protein compare
Pf6N2E2_5584 -0.8 -1.7 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_2188 -0.7 -2.3 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_4764 -0.7 -4.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2706 -0.7 -1.6 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_2261 -0.7 -4.1 VacJ-like lipoprotein precursor compare
Pf6N2E2_5252 -0.7 -1.1 FIG00956396: hypothetical protein compare
Pf6N2E2_546 -0.7 -1.2 FIG00966904: hypothetical protein compare
Pf6N2E2_6056 -0.7 -4.6 Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) compare
Pf6N2E2_5243 -0.7 -1.6 hypothetical protein compare
Pf6N2E2_4601 -0.7 -1.4 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_3835 -0.7 -3.2 Carboxyl-terminal protease (EC 3.4.21.102) compare


Specific Phenotypes

For 14 genes in this experiment

For carbon source L-Phenylalanine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Phenylalanine across organisms