Experiment set2IT027 for Shewanella loihica PV-4

Compare to:

LB with Paraquat dichloride 10 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_2049 +4.1 10.4 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_3377 +4.1 1.7 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_1298 guaA +3.7 24.3 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_3378 +3.2 3.4 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_1819 +2.9 6.0 GntR family transcriptional regulator (RefSeq) compare
Shew_1341 +2.9 6.5 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_0296 +2.9 2.0 heat shock protein Hsp20 (RefSeq) compare
Shew_1224 +2.8 19.2 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1058 +2.7 14.0 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_2642 +2.6 5.0 flavodoxin (RefSeq) compare
Shew_0570 +2.6 2.1 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_2572 +2.6 9.2 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1992 +2.6 6.0 hypothetical protein (RefSeq) compare
Shew_0755 +2.4 4.5 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_1011 +2.4 9.1 citrate transporter (RefSeq) compare
Shew_3273 +2.4 10.9 hypothetical protein (RefSeq) compare
Shew_3682 +2.3 15.4 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_3681 +2.2 15.9 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_1092 +2.2 9.5 amino acid carrier protein (RefSeq) compare
Shew_3431 aceE +2.1 13.6 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_1563 +2.1 9.1 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_1865 +2.0 5.1 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_3432 pdhR +2.0 3.0 transcriptional regulator PdhR (RefSeq) compare
Shew_2061 +1.9 2.2 radical SAM domain-containing protein (RefSeq) compare
Shew_1810 +1.9 4.7 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_3295 +1.9 10.6 AFG1 family ATPase (RefSeq) compare
Shew_3063 +1.9 2.6 glycine cleavage system protein H (RefSeq) compare
Shew_3664 +1.9 13.3 alpha-L-glutamate ligase (RefSeq) compare
Shew_1078 +1.9 10.6 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_1657 sucC +1.9 1.9 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_3500 +1.9 3.4 putative endoribonuclease L-PSP (RefSeq) compare
Shew_3487 pyrE +1.9 6.8 orotate phosphoribosyltransferase (RefSeq) compare
Shew_0220 +1.8 5.3 phosphoglycolate phosphatase (RefSeq) compare
Shew_0728 +1.8 11.5 dihydroorotase (RefSeq) compare
Shew_1987 +1.7 4.3 Cbb3-type cytochrome oxidase component (RefSeq) compare
Shew_3710 tdh +1.7 6.3 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_2409 +1.7 4.7 short chain dehydrogenase (RefSeq) compare
Shew_1202 +1.7 7.3 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_0799 +1.7 3.0 MarR family transcriptional regulator (RefSeq) compare
Shew_1926 +1.7 3.5 transketolase, central region (RefSeq) compare
Shew_2320 +1.7 7.0 RNA methyltransferase (RefSeq) compare
Shew_1186 +1.7 3.4 transcriptional regulator NrdR (RefSeq) compare
Shew_1990 +1.6 2.8 heavy metal translocating P-type ATPase (RefSeq) compare
Shew_1437 +1.6 7.4 transcriptional regulator, TyrR (RefSeq) compare
Shew_1644 +1.6 1.2 DSBA oxidoreductase (RefSeq) compare
Shew_2584 +1.5 9.0 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_0086 +1.5 11.1 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_2153 +1.5 1.6 LysR family transcriptional regulator (RefSeq) compare
Shew_0421 +1.5 1.2 phage shock protein C, PspC (RefSeq) compare
Shew_0057 +1.5 4.1 cytoplasmic chaperone TorD family protein (RefSeq) compare
Shew_3483 dut +1.5 1.5 deoxyuridine 5'-triphosphate nucleotidohydrolase (RefSeq) compare
Shew_2000 +1.5 1.7 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_2573 +1.5 8.2 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_1782 +1.4 7.3 MarR family transcriptional regulator (RefSeq) compare
Shew_3131 +1.4 5.0 poly(A) polymerase (RefSeq) compare
Shew_0571 +1.4 1.8 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shew_1714 +1.4 2.1 alpha/beta hydrolase fold (RefSeq) compare
Shew_1445 +1.4 0.9 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), small permease component (from data) compare
Shew_3064 gcvT +1.4 5.2 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_3498 rpoZ +1.4 2.0 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_3267 +1.4 6.5 sodium/hydrogen exchanger (RefSeq) compare
Shew_1287 +1.4 4.3 hypothetical protein (RefSeq) compare
Shew_3388 +1.4 0.7 hypothetical protein (RefSeq) compare
Shew_1769 +1.3 1.6 NapD family protein (RefSeq) compare
Shew_2571 +1.3 8.2 propionyl-CoA carboxylase (RefSeq) compare
Shew_1995 +1.3 1.6 PP-loop domain-containing protein (RefSeq) compare
Shew_3709 +1.3 7.8 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_3271 +1.3 8.4 galactokinase (RefSeq) compare
Shew_0462 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_1555 +1.3 2.1 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_0618 +1.3 2.0 hypothetical protein (RefSeq) compare
Shew_3247 +1.3 1.1 hypothetical protein (RefSeq) compare
Shew_1013 +1.2 7.2 aspartate carbamoyltransferase (RefSeq) compare
Shew_1812 +1.2 5.4 23S rRNA m(2)G2445 methyltransferase (RefSeq) compare
Shew_0301 +1.2 1.2 AsnC family transcriptional regulator (RefSeq) compare
Shew_3499 +1.2 4.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_1985 +1.2 2.3 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shew_1673 fabG +1.2 1.1 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_3442 +1.2 2.3 hypothetical protein (RefSeq) compare
Shew_1925 +1.2 5.2 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_3430 +1.1 1.9 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_2403 +1.1 1.4 arylesterase (RefSeq) compare
Shew_2838 carB +1.1 6.3 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_3625 +1.1 2.2 sodium:dicarboxylate symporter (RefSeq) compare
Shew_0860 +1.1 1.7 hypothetical protein (RefSeq) compare
Shew_1646 +1.1 1.1 beta-lactamase domain-containing protein (RefSeq) compare
Shew_0614 +1.1 3.7 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_0121 +1.1 1.0 hypothetical protein (RefSeq) compare
Shew_2839 +1.1 7.6 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_0216 +1.1 0.8 DNA adenine methylase (RefSeq) compare
Shew_2211 +1.1 2.6 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) compare
Shew_0390 +1.1 1.0 MSHA biogenesis protein MshM (RefSeq) compare
Shew_2026 +1.1 2.2 alanine dehydrogenase (RefSeq) compare
Shew_3311 +1.0 4.3 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_0718 +1.0 2.2 cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) compare
Shew_2668 +1.0 4.7 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_0854 +1.0 2.7 hypothetical protein (RefSeq) compare
Shew_2666 +1.0 5.5 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_2804 +1.0 1.2 type IV pilus assembly PilZ (RefSeq) compare
Shew_0613 +1.0 2.9 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_3683 +1.0 3.2 extracellular solute-binding protein (RefSeq) compare
Shew_1223 +1.0 0.8 hypothetical protein (RefSeq) compare
Shew_3065 +1.0 3.6 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_0226 +1.0 2.1 hypothetical protein (RefSeq) compare
Shew_1521 +1.0 2.5 OmpA/MotB domain-containing protein (RefSeq) compare
Shew_0091 +1.0 2.6 molybdopterin biosynthesis MoaE (RefSeq) compare
Shew_1920 +1.0 3.0 alpha/beta hydrolase fold (RefSeq) compare
Shew_2644 +0.9 2.0 hypothetical protein (RefSeq) compare
Shew_3716 +0.9 1.9 cytochrome c, class I (RefSeq) compare
Shew_1962 +0.9 1.7 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase (RefSeq) compare
Shew_3653 +0.9 1.0 hypothetical protein (RefSeq) compare
Shew_0843 +0.9 5.3 nitrate/nitrite sensor protein NarQ (RefSeq) compare
Shew_3537 +0.9 1.7 hypothetical protein (RefSeq) compare
Shew_1678 +0.9 1.1 hypothetical protein (RefSeq) compare
Shew_2643 +0.9 1.0 pseudouridylate synthase (RefSeq) compare
Shew_1669 +0.9 3.9 butyryl-CoA dehydrogenase (RefSeq) compare
Shew_1518 +0.9 0.9 hypothetical protein (RefSeq) compare
Shew_3443 +0.9 1.7 hypothetical protein (RefSeq) compare
Shew_2481 +0.9 4.7 porin (RefSeq) compare
Shew_0546 +0.9 2.8 hypothetical protein (RefSeq) compare
Shew_0584 +0.9 0.8 hypothetical protein (RefSeq) compare
Shew_2121 +0.9 1.3 diguanylate cyclase (RefSeq) compare
Shew_1927 +0.9 1.0 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_0914 +0.9 2.9 NADPH-dependent FMN reductase (RefSeq) compare
Shew_0839 +0.9 2.1 WD-40 repeat-containing protein (RefSeq) compare
Shew_3080 +0.9 2.0 thiol:disulfide interchange protein, putative (RefSeq) compare
Shew_1425 +0.9 2.6 adenylyl-sulfate kinase (RefSeq) compare
Shew_0620 +0.8 1.1 ion transport 2 domain-containing protein (RefSeq) compare
Shew_3772 +0.8 1.0 thioesterase superfamily protein (RefSeq) compare
Shew_1163 +0.8 1.5 RND family efflux transporter MFP subunit (RefSeq) compare
Shew_0127 +0.8 2.3 LexA repressor (RefSeq) compare
Shew_2350 +0.8 1.2 2OG-Fe(II) oxygenase (RefSeq) compare
Shew_2700 +0.8 1.9 antibiotic biosynthesis monooxygenase (RefSeq) compare
Shew_1315 +0.8 2.6 hypothetical protein (RefSeq) compare
Shew_0942 +0.8 3.1 RDD domain-containing protein (RefSeq) compare
Shew_3069 +0.8 0.9 5-formyltetrahydrofolate cyclo-ligase (RefSeq) compare
Shew_1546 +0.8 1.7 thioesterase superfamily protein (RefSeq) compare
Shew_0054 +0.8 3.8 hypothetical protein (RefSeq) compare
Shew_3389 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_1455 +0.8 0.6 dual specificity protein phosphatase (RefSeq) compare
Shew_0738 +0.8 0.7 NTPase (RefSeq) compare
Shew_1776 +0.8 2.6 acetolactate synthase 3 catalytic subunit (RefSeq) compare
Shew_1514 upp +0.8 2.0 uracil phosphoribosyltransferase (RefSeq) compare
Shew_3324 +0.8 3.3 hypothetical protein (RefSeq) compare
Shew_2957 +0.8 2.1 hypothetical protein (RefSeq) compare
Shew_1557 +0.8 2.9 cupin 4 family protein (RefSeq) compare
Shew_3188 +0.8 4.3 aromatic amino acid permease (RefSeq) compare
Shew_2639 +0.8 1.4 hypothetical protein (RefSeq) compare
Shew_0647 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_1188 +0.8 1.3 riboflavin synthase subunit alpha (RefSeq) compare
Shew_0359 fre +0.8 3.5 FMN reductase (RefSeq) compare
Shew_2429 +0.8 0.6 hypothetical protein (RefSeq) compare
Shew_1606 +0.8 0.6 hypothetical protein (RefSeq) compare
Shew_0827 +0.8 0.7 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_1444 +0.8 1.5 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), large permease component (from data) compare
Shew_2132 +0.8 1.4 hypothetical protein (RefSeq) compare
Shew_2667 +0.8 5.7 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_1867 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_1840 +0.8 3.9 arsenate reductase (RefSeq) compare
Shew_1110 +0.8 1.6 nitrogen regulatory protein P-II (RefSeq) compare
Shew_0842 +0.8 1.3 two component LuxR family transcriptional regulator (RefSeq) compare
Shew_3049 +0.8 2.0 major facilitator transporter (RefSeq) compare
Shew_1146 +0.8 2.5 hypothetical protein (RefSeq) compare
Shew_2656 +0.8 4.1 4'-phosphopantetheinyl transferase (RefSeq) compare
Shew_0450 +0.8 2.8 1-acyl-sn-glycerol-3-phosphate acyltransferase (RefSeq) compare
Shew_0434 +0.8 1.9 hypothetical protein (RefSeq) compare
Shew_3621 +0.8 3.2 RNA-binding S4 domain-containing protein (RefSeq) compare
Shew_1583 yebU +0.7 2.2 rRNA (cytosine-C(5)-)-methyltransferase RsmF (RefSeq) compare
Shew_0097 +0.7 1.8 two component transcriptional regulator (RefSeq) compare
Shew_0788 +0.7 2.0 dienelactone hydrolase (RefSeq) compare
Shew_1456 +0.7 2.0 phospholipase D/transphosphatidylase (RefSeq) compare
Shew_0191 +0.7 2.4 cytochrome c, class I (RefSeq) compare
Shew_3268 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_2340 +0.7 1.5 redoxin domain-containing protein (RefSeq) compare
Shew_2558 +0.7 2.0 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_2389 +0.7 2.3 hypothetical protein (RefSeq) compare
Shew_2423 +0.7 1.6 hypothetical protein (RefSeq) compare
Shew_1510 +0.7 1.1 peptidase M28 (RefSeq) compare
Shew_3051 +0.7 2.5 cupin 2 domain-containing protein (RefSeq) compare
Shew_2494 +0.7 1.3 phage shock protein C, PspC (RefSeq) compare
Shew_3549 +0.7 1.9 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_1210 +0.7 1.6 stationary-phase survival protein SurE (RefSeq) compare
Shew_0932 +0.7 0.9 radical SAM domain-containing protein (RefSeq) compare
Shew_1422 +0.7 0.6 sulfate adenylyltransferase subunit 2 (RefSeq) compare
Shew_2665 +0.7 5.3 beta-ketoacyl synthase (RefSeq) compare
Shew_1587 +0.7 3.3 DNA ligase (RefSeq) compare
Shew_1713 +0.7 0.6 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_2821 +0.7 2.9 lipoprotein NlpI (RefSeq) compare
Shew_2795 +0.7 2.4 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_1278 +0.7 0.4 hypothetical protein (RefSeq) compare
Shew_1543 +0.7 2.2 secretion protein HlyD family protein (RefSeq) compare
Shew_3167 +0.7 1.5 hypothetical protein (RefSeq) compare
Shew_2570 +0.7 4.5 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_3379 +0.7 1.4 hypothetical protein (RefSeq) compare
Shew_1133 +0.7 3.3 hypothetical protein (RefSeq) compare
Shew_1313 +0.7 2.0 TetR family transcriptional regulator (RefSeq) compare
Shew_0056 +0.7 4.4 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_2544 +0.7 0.8 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) compare
Shew_2589 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_1828 +0.7 1.8 peptidoglycan binding domain-containing protein (RefSeq) compare


Specific Phenotypes

For 2 genes in this experiment

For stress Paraquat dichloride in Shewanella loihica PV-4

For stress Paraquat dichloride across organisms