Experiment set2IT025 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_77 -6.7 -4.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4597 -6.2 -9.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4596 -6.2 -9.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3630 -5.9 -8.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3782 -5.3 -6.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3060 -5.2 -5.1 Outer membrane protein H precursor compare
Pf6N2E2_71 -5.2 -7.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3751 -5.2 -15.9 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5527 -5.2 -4.5 Cold shock protein CspC compare
Pf6N2E2_4825 -5.1 -11.8 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4391 -5.1 -4.9 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_5175 -5.0 -18.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_5014 -5.0 -2.0 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3839 -4.9 -7.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3783 -4.9 -7.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_2753 -4.9 -4.7 HtrA protease/chaperone protein compare
Pf6N2E2_4279 -4.9 -15.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3248 -4.7 -6.8 Probable transmembrane protein compare
Pf6N2E2_4047 -4.6 -8.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5006 -4.4 -12.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_1381 -4.4 -10.5 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_4278 -4.4 -12.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3752 -4.4 -21.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4759 -4.3 -19.5 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3253 -4.2 -9.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3610 -4.2 -7.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3942 -4.2 -15.1 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4826 -4.1 -10.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4564 -4.1 -11.0 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3841 -4.1 -8.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3842 -4.0 -7.4 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3932 -4.0 -5.6 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5723 -4.0 -16.2 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5160 -3.9 -2.2 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_5177 -3.9 -11.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4390 -3.9 -9.5 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system conserved
Pf6N2E2_3661 -3.9 -7.8 hypothetical protein compare
Pf6N2E2_4803 -3.9 -2.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_5156 -3.8 -3.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4418 -3.6 -1.4 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_50 -3.6 -10.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3349 -3.6 -5.3 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3940 -3.6 -10.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4048 -3.6 -8.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4277 -3.5 -11.2 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2513 -3.5 -6.4 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_66 -3.4 -8.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_64 -3.4 -3.7 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5666 -3.3 -10.8 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3252 -3.2 -8.6 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2510 -3.2 -7.0 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5176 -3.1 -9.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3941 -3.0 -3.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_4372 -2.9 -7.5 FIG00460773: hypothetical protein compare
Pf6N2E2_2074 -2.9 -2.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_63 -2.9 -5.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3346 -2.9 -9.2 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4638 -2.9 -5.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2022 -2.8 -9.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3271 -2.8 -2.4 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_4453 -2.8 -17.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3460 -2.7 -3.1 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3270 -2.7 -6.7 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_5720 -2.7 -14.3 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_5780 -2.6 -10.5 Periplasmic protease compare
Pf6N2E2_2574 -2.6 -3.6 Flagellar synthesis regulator FleN compare
Pf6N2E2_4352 -2.6 -3.8 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_4764 -2.6 -7.4 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2473 -2.5 -1.9 Major outer membrane lipoprotein I compare
Pf6N2E2_2507 -2.5 -7.4 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5579 -2.5 -6.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_1932 -2.5 -5.5 Transcriptional regulator, IclR family compare
Pf6N2E2_1056 -2.4 -1.2 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_5459 -2.4 -11.0 D-serine/D-alanine/glycine transporter conserved
Pf6N2E2_4624 -2.4 -1.5 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_3251 -2.3 -9.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2277 -2.3 -3.3 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2073 -2.3 -8.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4071 -2.3 -5.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4763 -2.3 -10.9 Biotin synthesis protein BioC compare
Pf6N2E2_5219 -2.3 -9.6 FIG140336: TPR domain protein compare
Pf6N2E2_5841 -2.2 -1.6 GlcG protein compare
Pf6N2E2_5950 -2.2 -5.5 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_5338 -2.2 -9.6 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_3786 -2.2 -3.4 Twin-arginine translocation protein TatC compare
Pf6N2E2_4187 -2.1 -4.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2258 -2.1 -8.8 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2218 -2.1 -5.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_1545 -2.1 -6.5 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_4761 -2.1 -11.2 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5316 -2.1 -2.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2752 -2.1 -9.8 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_5337 -2.1 -4.9 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_3170 -2.0 -5.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_1400 -1.9 -10.6 Sensory box histidine kinase/response regulator compare
Pf6N2E2_5430 -1.9 -10.5 Transglycosylase, Slt family compare
Pf6N2E2_5328 -1.9 -5.5 FIG00958649: hypothetical protein compare
Pf6N2E2_2318 -1.8 -9.7 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3835 -1.8 -3.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_4762 -1.8 -4.7 Biotin synthesis protein BioH compare
Pf6N2E2_4631 -1.8 -6.9 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_2186 -1.8 -7.5 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2217 -1.7 -6.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2508 -1.7 -5.6 hypothetical protein compare
Pf6N2E2_5536 -1.7 -2.0 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3663 -1.7 -7.5 Glycosyl transferase compare
Pf6N2E2_3899 -1.7 -7.2 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5553 -1.7 -6.2 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5001 -1.7 -3.2 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3834 -1.7 -6.8 Lipoprotein NlpD compare
Pf6N2E2_5544 -1.7 -8.2 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_3300 -1.6 -3.8 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_3062 -1.6 -5.6 Membrane-associated zinc metalloprotease compare
Pf6N2E2_3984 -1.6 -9.0 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5339 -1.6 -6.2 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_445 -1.6 -6.2 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_2320 -1.6 -4.1 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_2311 -1.5 -8.0 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_2317 -1.5 -3.7 Putative analog of CcoH, COG3198 compare
Pf6N2E2_4205 -1.5 -5.6 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_5027 -1.5 -9.4 AMP nucleosidase (EC 3.2.2.4) compare
Pf6N2E2_1402 -1.5 -5.3 hypothetical protein compare
Pf6N2E2_2178 -1.5 -6.4 FIG00960144: hypothetical protein compare
Pf6N2E2_3461 -1.5 -1.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5667 -1.5 -6.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4611 -1.5 -3.7 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2313 -1.5 -3.0 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_2526 -1.4 -4.8 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_3761 -1.4 -12.0 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_4160 -1.4 -1.7 Cytochrome c5 compare
Pf6N2E2_621 -1.4 -7.4 TPR domain protein in aerotolerance operon compare
Pf6N2E2_2919 -1.4 -2.3 FIG00955830: hypothetical protein compare
Pf6N2E2_2527 -1.4 -4.4 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_4585 -1.4 -8.7 Cell division protein FtsX compare
Pf6N2E2_89 -1.4 -3.0 hypothetical protein compare
Pf6N2E2_3833 -1.3 -3.0 hypothetical protein compare
Pf6N2E2_4499 -1.3 -2.1 protein of unknown function DUF86 compare
Pf6N2E2_3204 -1.3 -3.1 Rho-specific inhibitor of transcription termination (YaeO) compare
Pf6N2E2_2286 -1.3 -3.5 FIG00953287: hypothetical protein compare
Pf6N2E2_4810 -1.3 -5.4 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_4364 -1.3 -2.0 Protein YicC compare
Pf6N2E2_2264 -1.3 -3.3 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_2465 -1.3 -3.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5727 -1.3 -5.7 FIG00955360: hypothetical protein compare
Pf6N2E2_1676 -1.3 -1.7 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_6164 -1.3 -1.4 tRNA-Val-TAC compare
Pf6N2E2_5771 -1.3 -5.6 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_4159 -1.2 -3.2 Cytochrome c4 compare
Pf6N2E2_1870 -1.2 -2.8 hypothetical protein compare
Pf6N2E2_2309 -1.2 -2.2 hypothetical protein compare
Pf6N2E2_3198 -1.2 -2.2 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_1081 -1.2 -1.5 probable membrane protein YPO3302 compare
Pf6N2E2_2312 -1.2 -1.0 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_4969 -1.2 -1.4 hypothetical protein compare
Pf6N2E2_2310 -1.2 -7.7 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3885 -1.2 -2.3 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_3171 -1.2 -1.4 hypothetical protein compare
Pf6N2E2_622 -1.2 -4.3 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_1294 -1.1 -2.9 Carbon starvation protein A compare
Pf6N2E2_2714 -1.1 -1.9 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_2200 -1.1 -1.5 RNA polymerase sigma-54 factor RpoN compare
Pf6N2E2_4362 -1.1 -1.9 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_5943 -1.1 -2.7 hypothetical protein compare
Pf6N2E2_4601 -1.1 -1.8 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_3384 -1.1 -3.5 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3264 -1.1 -2.5 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3257 -1.1 -3.2 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_6065 -1.1 -2.5 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_3383 -1.1 -5.6 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4982 -1.1 -5.0 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) compare
Pf6N2E2_3826 -1.1 -4.9 Nitrogen regulation protein NR(I) compare
Pf6N2E2_3096 -1.1 -1.1 Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_624 -1.1 -3.7 hypothetical protein PA3071 compare
Pf6N2E2_2506 -1.1 -7.6 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_620 -1.1 -5.1 BatD compare
Pf6N2E2_5078 -1.1 -2.9 Carbon starvation protein A compare
Pf6N2E2_2514 -1.0 -3.2 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_1886 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_4009 -1.0 -5.0 GGDEF domain protein compare
Pf6N2E2_3516 -1.0 -1.9 Probable transmembrane protein compare
Pf6N2E2_4584 -1.0 -2.1 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_75 -1.0 -3.2 Colicin V production protein compare
Pf6N2E2_625 -1.0 -3.3 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_481 -1.0 -3.5 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) compare
Pf6N2E2_1762 -1.0 -3.5 putative lipase compare
Pf6N2E2_2852 -1.0 -6.5 GGDEF domain/EAL domain protein compare
Pf6N2E2_2717 -1.0 -2.6 putative cytoplasmic protein compare
Pf6N2E2_2674 -1.0 -1.2 FIG00953856: hypothetical protein compare
Pf6N2E2_1490 -1.0 -2.7 hypothetical protein compare
Pf6N2E2_2274 -1.0 -3.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_818 -1.0 -3.8 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_2488 -1.0 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4360 -1.0 -6.0 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_1492 -1.0 -2.3 No significant database matches compare
Pf6N2E2_2367 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_4733 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_1092 -0.9 -3.0 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
Pf6N2E2_2588 -0.9 -2.4 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_5181 -0.9 -5.8 Paraquat-inducible protein A compare
Pf6N2E2_1441 -0.9 -2.4 Uncharacterized oxidoreductase ydgJ (EC 1.-.-.-) compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source L-Alanine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Alanine across organisms