Experiment set2IT022 for Pseudomonas fluorescens FW300-N2E2

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L-Histidine carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.8 -6.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -6.3 -6.1 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4596 -6.1 -10.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -6.0 -8.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_1401 -5.8 -6.9 FIG00955631: hypothetical protein compare
Pf6N2E2_77 -5.8 -5.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4825 -5.8 -10.4 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4047 -5.7 -5.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5175 -5.4 -18.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4071 -5.3 -6.4 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4564 -5.2 -13.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3804 -5.1 -13.5 Cytosine/purine/uracil/thiamine/allantoin permease family protein conserved
Pf6N2E2_4759 -5.0 -19.8 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3630 -4.9 -8.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3617 -4.9 -6.9 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_2574 -4.9 -3.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_5176 -4.9 -12.9 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3799 -4.8 -6.0 Histidine ammonia-lyase (EC 4.3.1.3) (from data) conserved
Pf6N2E2_4048 -4.8 -10.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5177 -4.6 -13.5 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_1381 -4.6 -8.2 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_4077 -4.5 -4.3 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_2753 -4.5 -5.3 HtrA protease/chaperone protein compare
Pf6N2E2_5006 -4.4 -11.2 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3661 -4.4 -7.2 hypothetical protein compare
Pf6N2E2_2073 -4.4 -8.3 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5156 -4.3 -2.9 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2258 -4.2 -14.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3805 -4.1 -12.3 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
Pf6N2E2_3808 -4.0 -8.7 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) conserved
Pf6N2E2_2277 -4.0 -3.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_1402 -3.9 -7.8 hypothetical protein compare
Pf6N2E2_1932 -3.9 -8.9 Transcriptional regulator, IclR family compare
Pf6N2E2_2752 -3.9 -12.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3941 -3.9 -5.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3798 -3.8 -8.6 Imidazolonepropionase (EC 3.5.2.7) (from data) conserved
Pf6N2E2_302 -3.8 -7.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_1400 -3.8 -11.0 Sensory box histidine kinase/response regulator compare
Pf6N2E2_5252 -3.8 -3.6 FIG00956396: hypothetical protein compare
Pf6N2E2_4638 -3.7 -5.0 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5553 -3.6 -7.5 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_50 -3.6 -9.1 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5723 -3.5 -11.8 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_3062 -3.5 -7.5 Membrane-associated zinc metalloprotease compare
Pf6N2E2_66 -3.4 -9.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_5430 -3.4 -12.5 Transglycosylase, Slt family compare
Pf6N2E2_64 -3.4 -4.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_2074 -3.4 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3797 -3.4 -8.3 N-formylglutamate deformylase (EC 3.5.1.68) (from data) conserved
Pf6N2E2_5780 -3.2 -13.4 Periplasmic protease compare
Pf6N2E2_2507 -3.0 -8.4 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_4372 -3.0 -6.9 FIG00460773: hypothetical protein compare
Pf6N2E2_3834 -2.9 -8.7 Lipoprotein NlpD compare
Pf6N2E2_63 -2.9 -4.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3060 -2.8 -5.3 Outer membrane protein H precursor compare
Pf6N2E2_5160 -2.8 -3.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3762 -2.8 -8.1 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_2217 -2.7 -7.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5014 -2.7 -2.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5579 -2.7 -7.0 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3663 -2.7 -9.2 Glycosyl transferase compare
Pf6N2E2_3932 -2.6 -2.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4279 -2.5 -11.4 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_2510 -2.5 -6.7 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2508 -2.5 -3.5 hypothetical protein compare
Pf6N2E2_3803 -2.5 -8.2 Histidine ABC transporter, histidine-binding protein (TC 3.A.1) conserved
Pf6N2E2_4453 -2.5 -16.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4418 -2.5 -1.6 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3346 -2.5 -9.3 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_3835 -2.4 -5.0 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_3801 -2.4 -4.0 Histidine ABC transporter, ATP-binding protein (TC 3.A.1) compare
Pf6N2E2_4764 -2.4 -6.9 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_4810 -2.3 -9.2 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
Pf6N2E2_1056 -2.3 -1.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_4187 -2.3 -5.3 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2186 -2.3 -7.5 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4352 -2.3 -4.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3170 -2.3 -5.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4611 -2.3 -3.3 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_2588 -2.2 -4.2 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3655 -2.2 -12.5 Hypothetical protein FIG015671 in large core OS assembly cluster compare
Pf6N2E2_4075 -2.2 -6.8 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4584 -2.2 -4.5 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2465 -2.1 -7.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4278 -2.1 -9.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4059 -2.1 -2.1 DNA-binding protein HU-alpha compare
Pf6N2E2_3282 -2.1 -3.9 FIG005080: Possible exported protein compare
Pf6N2E2_4762 -2.1 -3.1 Biotin synthesis protein BioH compare
Pf6N2E2_4585 -2.1 -12.7 Cell division protein FtsX compare
Pf6N2E2_622 -2.1 -6.6 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_3802 -2.1 -2.6 Histidine ABC transporter, permease protein (TC 3.A.1) compare
Pf6N2E2_621 -2.1 -9.2 TPR domain protein in aerotolerance operon compare
Pf6N2E2_4631 -2.1 -9.5 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3833 -2.0 -4.4 hypothetical protein compare
Pf6N2E2_4803 -2.0 -2.3 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4362 -2.0 -5.0 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_4761 -2.0 -10.5 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5219 -2.0 -9.1 FIG140336: TPR domain protein compare
Pf6N2E2_2509 -2.0 -3.3 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_2526 -2.0 -7.3 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_4752 -2.0 -13.4 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_3349 -1.9 -3.0 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3800 -1.9 -4.4 Histidine ammonia-lyase (EC 4.3.1.3) compare
Pf6N2E2_3656 -1.8 -5.5 Probable transcription regulator Mig-14 compare
Pf6N2E2_4763 -1.8 -10.1 Biotin synthesis protein BioC compare
Pf6N2E2_5405 -1.8 -7.0 ABC transporter for D-Alanine, ATPase component (from data) compare
Pf6N2E2_2586 -1.8 -2.8 Hpt domain protein compare
Pf6N2E2_624 -1.8 -6.3 hypothetical protein PA3071 compare
Pf6N2E2_3460 -1.8 -2.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_5403 -1.8 -10.7 ABC transporter for D-Alanine, permease component 2 (from data) conserved
Pf6N2E2_2756 -1.7 -8.3 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_6058 -1.7 -6.2 FIG139976: hypothetical protein compare
Pf6N2E2_2513 -1.7 -4.3 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_5316 -1.7 -3.2 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_5158 -1.7 -4.9 FIG00954153: hypothetical protein compare
Pf6N2E2_5865 -1.6 -9.3 Chaperone protein HtpG compare
Pf6N2E2_5527 -1.6 -4.2 Cold shock protein CspC compare
Pf6N2E2_5178 -1.6 -2.2 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3984 -1.6 -8.8 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3659 -1.6 -6.1 Protein fixF compare
Pf6N2E2_5242 -1.6 -2.3 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5157 -1.6 -8.6 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4072 -1.6 -5.1 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_4009 -1.6 -9.2 GGDEF domain protein compare
Pf6N2E2_5255 -1.6 -10.0 Outer membrane stress sensor protease DegS compare
Pf6N2E2_4159 -1.6 -4.0 Cytochrome c4 compare
Pf6N2E2_4351 -1.6 -9.9 Predicted signal transduction protein compare
Pf6N2E2_5339 -1.6 -7.3 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_2318 -1.5 -8.7 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_5402 -1.5 -8.6 ABC transporter for D-Alanine, periplasmic substrate-binding component (from data) conserved
Pf6N2E2_2506 -1.5 -11.4 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_6059 -1.5 -4.7 FIG008443: hypothetical protein compare
Pf6N2E2_75 -1.5 -4.8 Colicin V production protein compare
Pf6N2E2_4277 -1.5 -6.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3786 -1.4 -3.7 Twin-arginine translocation protein TatC compare
Pf6N2E2_4162 -1.4 -2.6 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_5727 -1.4 -6.6 FIG00955360: hypothetical protein compare
Pf6N2E2_625 -1.4 -4.6 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_6140 -1.4 -1.5 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_620 -1.4 -6.9 BatD compare
Pf6N2E2_1759 -1.4 -1.4 uncharacterized domain 1 compare
Pf6N2E2_4204 -1.4 -1.8 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_5555 -1.4 -1.7 Cold shock protein CspA compare
Pf6N2E2_5331 -1.4 -5.9 ATPase, AFG1 family compare
Pf6N2E2_2758 -1.4 -10.0 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_5524 -1.3 -9.6 Outer membrane porin, OprD family compare
Pf6N2E2_5337 -1.3 -5.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_3942 -1.3 -9.1 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_5508 -1.3 -1.5 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3461 -1.3 -1.9 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5338 -1.3 -8.0 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_5404 -1.3 -7.6 ABC transporter for D-Alanine, permease component 1 (from data) conserved
Pf6N2E2_3521 -1.3 -7.1 Sensor histidine kinase/response regulator compare
Pf6N2E2_4169 -1.2 -5.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4074 -1.2 -8.0 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_5771 -1.2 -6.6 FKBP-type peptidyl-prolyl cis-trans isomerase FklB (EC 5.2.1.8) compare
Pf6N2E2_4416 -1.2 -3.1 Tyrosine recombinase XerC compare
Pf6N2E2_2519 -1.2 -1.6 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_2340 -1.2 -3.3 Transcriptional regulator, GntR family compare
Pf6N2E2_4273 -1.2 -6.6 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5183 -1.2 -9.2 Paraquat-inducible protein B compare
Pf6N2E2_1596 -1.2 -2.4 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_180 -1.2 -4.3 Transcriptional regulator, MerR family compare
Pf6N2E2_3869 -1.2 -7.5 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_4084 -1.2 -6.0 Transcriptional regulator compare
Pf6N2E2_3074 -1.2 -2.0 FIG00960973: hypothetical protein compare
Pf6N2E2_51 -1.2 -4.8 hypothetical protein compare
Pf6N2E2_3344 -1.2 -4.1 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD compare
Pf6N2E2_2218 -1.1 -3.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5401 -1.1 -6.5 phospholipase/carboxylesterase family protein conserved
Pf6N2E2_510 -1.1 -8.1 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
Pf6N2E2_3612 -1.1 -1.9 HflK protein compare
Pf6N2E2_6057 -1.1 -2.3 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_2320 -1.1 -3.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_4630 -1.1 -3.5 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
Pf6N2E2_5664 -1.1 -4.8 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
Pf6N2E2_5567 -1.1 -2.2 Glutamate Aspartate transport ATP-binding protein GltL (TC 3.A.1.3.4) compare
Pf6N2E2_2727 -1.1 -5.9 Ribonuclease D (EC 3.1.26.3) compare
Pf6N2E2_5182 -1.1 -6.5 Paraquat-inducible protein A compare
Pf6N2E2_4478 -1.1 -5.3 FIG019278: hypothetical protein compare
Pf6N2E2_3132 -1.1 -3.4 FIG00954548: hypothetical protein compare
Pf6N2E2_5950 -1.1 -4.3 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_5766 -1.1 -1.6 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_2282 -1.0 -3.6 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_3713 -1.0 -3.2 Acyl carrier protein compare
Pf6N2E2_5243 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_3271 -1.0 -2.2 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_3763 -1.0 -1.4 hypothetical protein compare
Pf6N2E2_4272 -1.0 -3.2 putative membrane protein compare
Pf6N2E2_3312 -1.0 -4.1 Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) compare
Pf6N2E2_4618 -1.0 -4.3 Chemotaxis signal transduction protein compare
Pf6N2E2_5342 -1.0 -2.5 21 kDa hemolysin precursor compare
Pf6N2E2_5181 -1.0 -7.2 Paraquat-inducible protein A compare
Pf6N2E2_4097 -1.0 -6.6 FIG00953365: hypothetical protein compare
Pf6N2E2_5878 -1.0 -5.0 FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein compare
Pf6N2E2_3885 -1.0 -3.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_3134 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_5544 -0.9 -5.2 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf6N2E2_3192 -0.9 -2.8 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_2746 -0.9 -4.6 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare


Specific Phenotypes

For 21 genes in this experiment

For carbon source L-Histidine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Histidine across organisms