Experiment set2IT022 for Pseudomonas fluorescens FW300-N2E2

Compare to:

L-Histidine carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_1379 +6.5 43.8 Sensory box histidine kinase/response regulator compare
Pf6N2E2_1399 +6.2 39.7 Transcriptional regulator, LuxR family compare
Pf6N2E2_1389 +6.0 48.8 Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.99.8) compare
Pf6N2E2_1981 +5.8 9.1 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_1391 +5.5 25.8 DNA-binding response regulator, LuxR family compare
Pf6N2E2_1393 +5.4 29.3 hypothetical protein compare
Pf6N2E2_1392 +5.3 27.3 sensor histidine kinase compare
Pf6N2E2_828 +4.6 14.5 Transcriptional regulator, TetR family compare
Pf6N2E2_1387 +3.9 24.7 Cytochrome C550 (Soluble cytochrome C) compare
Pf6N2E2_1398 +3.7 6.3 Rhodanese-related sulfurtransferase compare
Pf6N2E2_3351 +3.7 16.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_2447 +3.1 17.9 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_3938 +3.0 26.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_1147 +2.9 8.0 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_4414 +2.5 10.5 FIG00953808: hypothetical protein compare
Pf6N2E2_5084 +2.5 20.0 Glutathione-regulated potassium-efflux system ATP-binding protein compare
Pf6N2E2_3264 +2.4 9.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_4776 +2.3 19.2 Coenzyme PQQ synthesis protein F compare
Pf6N2E2_5534 +2.2 13.9 FIG000859: hypothetical protein YebC compare
Pf6N2E2_5420 +2.2 15.5 Cytosol aminopeptidase PepA (EC 3.4.11.1) compare
Pf6N2E2_4365 +2.2 16.3 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_4772 +2.2 13.4 Coenzyme PQQ synthesis protein E compare
Pf6N2E2_5155 +2.2 9.0 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5425 +2.1 3.1 hypothetical protein compare
Pf6N2E2_4774 +2.0 14.4 Pyrroloquinoline-quinone synthase (EC 1.3.3.11) compare
Pf6N2E2_3899 +2.0 15.0 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5705 +2.0 4.2 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_4369 +1.9 7.0 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_2389 +1.9 14.6 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_2390 +1.7 5.9 FIG00959101: hypothetical protein compare
Pf6N2E2_1386 +1.7 9.8 amino acid ABC transporter, periplasmic substrate-binding protein compare
Pf6N2E2_2605 +1.6 8.2 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2552 +1.6 7.3 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_2312 +1.6 1.9 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_4775 +1.6 6.9 Coenzyme PQQ synthesis protein B conserved
Pf6N2E2_4980 +1.5 4.5 hypothetical protein compare
Pf6N2E2_5676 +1.5 6.4 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_3903 +1.5 8.3 Ribosomal protein S6 glutaminyl transferase compare
Pf6N2E2_2466 +1.4 7.7 Universal stress protein family compare
Pf6N2E2_5365 +1.4 8.5 Heavy metal sensor histidine kinase compare
Pf6N2E2_5406 +1.4 5.6 FIG00958224: hypothetical protein compare
Pf6N2E2_5520 +1.4 7.9 Sensory box histidine kinase compare
Pf6N2E2_3908 +1.3 9.2 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_4383 +1.3 10.4 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.99); 4-guanidinobutyraldehyde dehydrogenase (EC 1.2.1.54) (from data) compare
Pf6N2E2_2469 +1.3 3.8 hypothetical protein compare
Pf6N2E2_2646 +1.3 1.9 FIG00953416: hypothetical protein compare
Pf6N2E2_3037 +1.3 9.8 RNA polymerase sigma factor RpoS compare
Pf6N2E2_2279 +1.3 5.7 FIG00954981: hypothetical protein compare
Pf6N2E2_1980 +1.2 3.2 hypothetical protein compare
Pf6N2E2_2399 +1.2 7.9 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
Pf6N2E2_2181 +1.2 1.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_863 +1.2 6.0 Transcriptional regulator, IclR family compare
Pf6N2E2_525 +1.2 7.4 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2684 +1.2 9.2 Peptidyl-prolyl cis-trans isomerase PpiA precursor (EC 5.2.1.8) compare
Pf6N2E2_3829 +1.1 5.1 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_4556 +1.1 4.9 FIG00953078: hypothetical protein compare
Pf6N2E2_2384 +1.1 4.7 CmpX compare
Pf6N2E2_5258 +1.0 6.9 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_5666 +1.0 5.4 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_1382 +1.0 7.3 Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.99.8) compare
Pf6N2E2_2219 +1.0 1.7 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_3807 +0.9 5.5 Histidine utilization repressor compare
Pf6N2E2_1656 +0.9 2.2 hypothetical protein compare
Pf6N2E2_5257 +0.9 6.4 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2428 +0.9 3.4 Thiol-disulfide isomerase and thioredoxins compare
Pf6N2E2_6047 +0.9 2.4 hypothetical protein compare
Pf6N2E2_4054 +0.9 1.9 Osmotically inducible protein C compare
Pf6N2E2_1463 +0.9 2.1 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf6N2E2_5665 +0.9 5.6 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2253 +0.9 2.1 hypothetical protein compare
Pf6N2E2_5962 +0.9 6.0 Molybdenum cofactor biosynthesis protein MoaA compare
Pf6N2E2_1305 +0.9 1.0 Homoprotocatechuate degradative operon repressor compare
Pf6N2E2_5340 +0.9 4.5 Stringent starvation protein A compare
Pf6N2E2_5435 +0.9 3.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1083 +0.9 1.7 hypothetical protein compare
Pf6N2E2_2533 +0.9 6.4 Rhodanese domain protein UPF0176 compare
Pf6N2E2_2606 +0.9 3.3 hypothetical protein compare
Pf6N2E2_3303 +0.9 3.3 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf6N2E2_2201 +0.9 4.1 Transmembrane regulator protein PrtR compare
Pf6N2E2_942 +0.8 1.2 Mll6465 protein compare
Pf6N2E2_2472 +0.8 1.9 hypothetical protein compare
Pf6N2E2_4454 +0.8 5.0 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2468 +0.8 4.4 2-dehydropantoate 2-reductase (EC 1.1.1.169) compare
Pf6N2E2_1095 +0.8 1.9 Opine oxidase subunit C compare
Pf6N2E2_5872 +0.8 5.6 Sensor histidine kinase/response regulator compare
Pf6N2E2_2423 +0.8 5.3 Molybdenum cofactor biosynthesis protein MoaB compare
Pf6N2E2_5394 +0.8 4.0 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_1534 +0.8 2.0 Probable transmembrane protein compare
Pf6N2E2_2886 +0.8 7.2 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5392 +0.8 2.5 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_2681 +0.8 3.5 3-phosphoglycerate kinase compare
Pf6N2E2_5103 +0.8 1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2252 +0.8 4.4 NreA-like protein compare
Pf6N2E2_3667 +0.8 1.8 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3901 +0.8 2.0 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Pf6N2E2_2470 +0.8 5.7 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf6N2E2_5816 +0.8 0.8 Smr domain protein compare
Pf6N2E2_2344 +0.8 6.0 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3517 +0.8 4.2 tRNA dihydrouridine synthase B (EC 1.-.-.-) compare
Pf6N2E2_2999 +0.8 2.7 probable tail fiber assembly protein compare
Pf6N2E2_4815 +0.8 4.4 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_3568 +0.8 3.4 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_3009 +0.8 2.7 Phage tail tube protein compare
Pf6N2E2_693 +0.7 2.0 hypothetical protein compare
Pf6N2E2_750 +0.7 1.9 Transcriptional regulator, DeoR family compare
Pf6N2E2_2564 +0.7 3.3 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_3902 +0.7 2.9 Ribosomal protein S6 glutaminyl transferase compare
Pf6N2E2_5312 +0.7 2.2 FIG00964214: hypothetical protein compare
Pf6N2E2_1606 +0.7 3.2 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2422 +0.7 5.2 Molybdopterin biosynthesis protein MoeA compare
Pf6N2E2_719 +0.7 2.0 Molybdenum cofactor biosynthesis protein MoaB compare
Pf6N2E2_1817 +0.7 2.0 hypothetical protein compare
Pf6N2E2_4612 +0.7 4.6 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_1032 +0.7 1.2 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_2702 +0.7 3.3 FIG00962464: hypothetical protein compare
Pf6N2E2_4155 +0.7 5.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_2712 +0.7 4.6 Permeases of the major facilitator superfamily compare
Pf6N2E2_2477 +0.7 1.5 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_3891 +0.7 5.9 Putative formate dehydrogenase oxidoreductase protein compare
Pf6N2E2_82 +0.7 1.5 hypothetical protein compare
Pf6N2E2_1673 +0.7 1.7 Transcriptional regulator, TetR family compare
Pf6N2E2_445 +0.7 3.4 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_2845 +0.7 4.8 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
Pf6N2E2_4271 +0.7 4.4 FIG00956226: hypothetical protein compare
Pf6N2E2_5679 +0.7 3.7 hypothetical protein compare
Pf6N2E2_69 +0.7 4.0 Probable type IV pilus assembly FimV-related transmembrane protein compare
Pf6N2E2_2106 +0.7 0.6 hypothetical protein compare
Pf6N2E2_4427 +0.7 2.3 FIG00954215: hypothetical protein compare
Pf6N2E2_377 +0.7 1.8 hypothetical protein compare
Pf6N2E2_3770 +0.7 2.0 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_5667 +0.6 3.9 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5460 +0.6 2.9 Phage protein compare
Pf6N2E2_3820 +0.6 1.4 hypothetical protein compare
Pf6N2E2_5874 +0.6 5.8 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins compare
Pf6N2E2_3792 +0.6 4.1 Glucans biosynthesis protein G precursor compare
Pf6N2E2_3040 +0.6 4.0 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2471 +0.6 4.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3454 +0.6 2.3 hypothetical protein compare
Pf6N2E2_2847 +0.6 4.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3619 +0.6 3.8 NAD(P)HX epimerase / NAD(P)HX dehydratase compare
Pf6N2E2_2867 +0.6 3.6 hypothetical protein compare
Pf6N2E2_291 +0.6 2.5 ATP-dependent Clp protease adaptor protein ClpS compare
Pf6N2E2_1099 +0.6 1.8 Hypothetical protein GlcG in glycolate utilization operon compare
Pf6N2E2_2441 +0.6 3.2 putative ATP/GTP-binding protein compare
Pf6N2E2_1110 +0.6 2.2 FIG00964414: hypothetical protein compare
Pf6N2E2_2175 +0.6 2.7 Transcriptional regulator, RpiR family compare
Pf6N2E2_1033 +0.6 2.4 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components compare
Pf6N2E2_2825 +0.6 2.7 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_1281 +0.6 1.2 ATPase involved in DNA repair compare
Pf6N2E2_848 +0.6 2.7 hypothetical protein compare
Pf6N2E2_5902 +0.6 1.5 hypothetical protein compare
Pf6N2E2_3791 +0.6 4.5 Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-) compare
Pf6N2E2_4181 +0.6 1.3 Organic hydroperoxide resistance protein compare
Pf6N2E2_570 +0.6 2.2 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf6N2E2_1730 +0.6 2.7 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3107 +0.6 3.9 unknown, without homologous in databases compare
Pf6N2E2_4635 +0.6 3.9 ATP-dependent RNA helicase RhlE compare
Pf6N2E2_92 +0.6 2.2 hypothetical protein compare
Pf6N2E2_2438 +0.6 1.4 hypothetical protein compare
Pf6N2E2_1450 +0.6 1.6 FIG00960438: hypothetical protein compare
Pf6N2E2_2755 +0.6 1.5 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_1979 +0.6 2.4 Cytosine-specific DNA methyltransferase (EC 2.1.1.37) compare
Pf6N2E2_5025 +0.6 5.4 Sensor histidine kinase compare
Pf6N2E2_1699 +0.6 1.3 FIG00955832: hypothetical protein compare
Pf6N2E2_924 +0.6 1.6 Transcriptional regulator XdhR, TetR family compare
Pf6N2E2_2464 +0.6 3.6 Transcription elongation factor compare
Pf6N2E2_6085 +0.6 1.0 Aha1 domain superfamily compare
Pf6N2E2_2474 +0.6 3.8 ErfK/YbiS/YcfS/YnhG family protein compare
Pf6N2E2_414 +0.6 1.9 Chemotaxis protein CheD compare
Pf6N2E2_827 +0.6 1.4 probable dioxygenase compare
Pf6N2E2_5237 +0.6 1.9 Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) compare
Pf6N2E2_2436 +0.6 2.4 DNA-binding response regulator, LuxR family compare
Pf6N2E2_3603 +0.5 3.2 FIG003573: hypothetical protein compare
Pf6N2E2_4437 +0.5 2.6 Twin-arginine translocation protein TatB compare
Pf6N2E2_5461 +0.5 1.5 Ferredoxin-dependent glutamate synthase (EC 1.4.7.1) compare
Pf6N2E2_2467 +0.5 2.8 5'-nucleotidase (EC 3.1.3.5) compare
Pf6N2E2_5086 +0.5 1.1 hypothetical protein compare
Pf6N2E2_1434 +0.5 1.0 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_1625 +0.5 1.3 Ferric reductase (1.6.99.14) compare
Pf6N2E2_1248 +0.5 1.7 MutT/nudix family protein compare
Pf6N2E2_4963 +0.5 1.4 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_3606 +0.5 3.8 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) compare
Pf6N2E2_361 +0.5 2.2 Peptide ABC transporter, permease protein compare
Pf6N2E2_3539 +0.5 1.8 FIG00955840: hypothetical protein compare
Pf6N2E2_4359 +0.5 1.3 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1124 +0.5 1.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4624 +0.5 0.9 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_4121 +0.5 2.9 Ribosomal RNA small subunit methyltransferase B (EC 2.1.1.-) compare
Pf6N2E2_5020 +0.5 2.1 FIG00955339: hypothetical protein compare
Pf6N2E2_4417 +0.5 2.2 Protein of unknown function DUF484 compare
Pf6N2E2_3588 +0.5 2.2 hypothetical protein compare
Pf6N2E2_3634 +0.5 1.0 Transporter compare
Pf6N2E2_204 +0.5 0.6 hypothetical protein compare
Pf6N2E2_3641 +0.5 2.1 ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
Pf6N2E2_4430 +0.5 4.3 Autolysis response regulater LytR compare
Pf6N2E2_2754 +0.5 1.3 Sigma factor RpoE negative regulatory protein RseB precursor compare
Pf6N2E2_705 +0.5 2.3 Cytochrome cd1 nitrite reductase (EC:1.7.2.1) compare
Pf6N2E2_288 +0.5 1.7 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_5229 +0.5 3.2 Transcriptional regulator, MerR family, associated with photolyase compare
Pf6N2E2_3489 +0.5 4.3 FIG00956297: hypothetical protein compare


Specific Phenotypes

For 21 genes in this experiment

For carbon source L-Histidine in Pseudomonas fluorescens FW300-N2E2

For carbon source L-Histidine across organisms