Experiment set2IT021 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS07845		-1.3	-4.0	LL-diaminopimelate aminotransferase
MMP_RS05355		-1.1	-1.1	hypothetical protein
MMP_RS06130		-1.1	-3.8	peptidylprolyl isomerase
MMP_RS07605		-0.9	-3.8	diadenylate cyclase
MMP_RS06855		-0.8	-5.6	hypothetical protein
MMP_RS08440		-0.8	-2.6	cell division protein SepF
MMP_RS07005		-0.8	-0.8	4Fe-4S binding protein
MMP_RS08280		-0.8	-2.9	proteasome assembly chaperone family protein
MMP_RS07390		-0.8	-2.5	cell division protein FtsZ
MMP_RS06630		-0.8	-1.1	UPF0058 family protein
MMP_RS06530		-0.8	-3.9	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS06230		-0.8	-2.1	helix-turn-helix domain-containing protein
MMP_RS08155		-0.7	-3.8	hypothetical protein
MMP_RS01775		-0.7	-1.8	TIGR00297 family protein
MMP_RS06315		-0.7	-0.9	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS06625		-0.7	-2.0	DNA primase
MMP_RS02310		-0.7	-1.4	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS08790		-0.7	-1.5	translation initiation factor IF-2 subunit alpha
MMP_RS08760		-0.7	-2.6	hypothetical protein
MMP_RS03895		-0.6	-1.8	hypothetical protein
MMP_RS06865		-0.6	-1.6	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS06435		-0.6	-3.5	CBS domain-containing protein
MMP_RS02345		-0.6	-2.1	GTP-dependent dephospho-CoA kinase family protein
MMP_RS06535		-0.6	-3.2	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS06555		-0.6	-2.1	cupin domain-containing protein
MMP_RS06925		-0.6	-1.7	ribonuclease VapC4
MMP_RS03305		-0.5	-3.2	winged helix-turn-helix domain-containing protein
MMP_RS07380		-0.5	-1.6	transcription elongation factor Spt5
MMP_RS04265		-0.5	-1.4	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06120		-0.5	-1.3	UPF0147 family protein
MMP_RS01270		-0.5	-4.2	prepilin peptidase
MMP_RS01540		-0.5	-1.9	DUF504 domain-containing protein
MMP_RS06270		-0.5	-2.5	TIGR00300 family protein
MMP_RS04585		-0.5	-3.6	AIR synthase related protein
MMP_RS00985		-0.5	-2.8	CDC48 family AAA ATPase
MMP_RS03555		-0.5	-2.7	transcriptional regulator
MMP_RS01755		-0.5	-0.8	DUF2097 domain-containing protein
MMP_RS08435		-0.5	-0.9	Era-like GTP-binding protein
MMP_RS01460		-0.5	-1.8	hypothetical protein
MMP_RS00810		-0.5	-3.3	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS08785		-0.5	-0.7	RNA-protein complex protein Nop10
MMP_RS03250		-0.5	-2.1	MJ1244 family protein
MMP_RS01700		-0.4	-0.5	dihydroxy-acid dehydratase
MMP_RS01545		-0.4	-0.6	CBS domain-containing protein
MMP_RS00770		-0.4	-2.0	hypothetical protein
MMP_RS03840		-0.4	-1.9	hypothetical protein
MMP_RS07645		-0.4	-2.4	aldehyde dehydrogenase family protein
MMP_RS06885		-0.4	-1.3	50S ribosome-binding GTPase
MMP_RS00400		-0.4	-2.4	tributyrin esterase
MMP_RS01675		-0.4	-0.8	hypothetical protein
MMP_RS03320		-0.4	-1.0	metal-dependent transcriptional regulator
MMP_RS07580		-0.4	-1.5	DUF356 domain-containing protein
MMP_RS08365		-0.4	-1.5	energy conserving hydrogenase EhbF
MMP_RS08370		-0.4	-0.3	cation:proton antiporter subunit C
MMP_RS00655		-0.4	-1.4	hypothetical protein
MMP_RS01385		-0.4	-0.3	imidazole glycerol phosphate synthase subunit HisH
MMP_RS03700		-0.4	-2.5	sodium:proton antiporter
MMP_RS05250		-0.4	-0.6	NFYB/HAP3 family transcription factor subunit
MMP_RS08645		-0.4	-1.9	UPF0179 family protein
MMP_RS01720		-0.4	-0.9	replication factor C large subunit
MMP_RS06895		-0.4	-0.7	selenocysteine-specific translation elongation factor
MMP_RS07680		-0.4	-1.8	DUF366 family protein
MMP_RS02940		-0.4	-2.3	TatD family hydrolase
MMP_RS06605		-0.4	-2.9	DUF5814 domain-containing protein
MMP_RS05345		-0.4	-2.1	hypothetical protein
MMP_RS00300		-0.4	-0.4	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS00305		-0.4	-0.8	phosphoribosyl-ATP diphosphatase
MMP_RS01365		-0.4	-1.5	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS01275		-0.4	-1.9	class III signal peptide-containing protein
MMP_RS05765		-0.4	-1.5	M42 family metallopeptidase
MMP_RS02170		-0.4	-1.9	CBS domain-containing protein
MMP_RS08585		-0.4	-2.1	flagellin
MMP_RS04630		-0.4	-1.4	3'-5' exonuclease
MMP_RS07685		-0.3	-2.2	TIGR01212 family radical SAM protein
MMP_RS07420		-0.3	-1.7	metalloregulator ArsR/SmtB family transcription factor
MMP_RS00040		-0.3	-2.0	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS05990		-0.3	-1.2	DsrE family protein
MMP_RS08070		-0.3	-2.1	DUF2096 domain-containing protein
MMP_RS05295		-0.3	-2.3	minichromosome maintenance protein MCM
MMP_RS00320		-0.3	-0.5	class I SAM-dependent methyltransferase
MMP_RS01685		-0.3	-1.0	indolepyruvate oxidoreductase subunit beta
MMP_RS03800		-0.3	-1.1	hypothetical protein
MMP_RS02725		-0.3	-2.3	molybdate ABC transporter permease subunit
MMP_RS03140		-0.3	-2.8	hypothetical protein
MMP_RS07335		-0.3	-2.0	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS05430		-0.3	-2.2	TIGR00288 family NYN domain-containing protein
MMP_RS08360		-0.3	-1.4	hypothetical protein
MMP_RS09025		-0.3	-0.5	hypothetical protein
MMP_RS02595		-0.3	-0.5	putative zinc-binding protein
MMP_RS03440		-0.3	-0.5	MoaD/ThiS family protein
MMP_RS00635		-0.3	-1.5	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS02495		-0.3	-1.0	hypothetical protein
MMP_RS04015		-0.3	-1.0	hypothetical protein
MMP_RS00140		-0.3	-1.2	DUF192 domain-containing protein
MMP_RS06485		-0.3	-0.4	zinc ribbon domain-containing protein
MMP_RS06600		-0.3	-0.7	class III signal peptide-containing protein
MMP_RS08580		-0.3	-1.1	flagellin
MMP_RS04090		-0.3	-0.8	hypothetical protein
MMP_RS02265		-0.3	-1.0	nitroreductase family protein
MMP_RS05635		-0.3	-2.0	NAD-dependent epimerase/dehydratase family protein
MMP_RS02970		-0.3	-1.8	hypothetical protein
MMP_RS01310		-0.3	-2.1	hypothetical protein
MMP_RS08445		-0.3	-1.2	DUF2099 family protein
MMP_RS04715		-0.3	-2.2	CBS domain-containing protein
MMP_RS06340		-0.3	-1.6	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06730		-0.3	-0.6	phosphopantothenate/pantothenate synthetase
MMP_RS00625		-0.3	-2.0	hypothetical protein
MMP_RS04325		-0.3	-1.4	MtaA/CmuA family methyltransferase
MMP_RS09010		-0.3	-1.7	hypothetical protein
MMP_RS02815		-0.3	-1.0	hypothetical protein
MMP_RS03095		-0.3	-1.8	diphthine synthase
MMP_RS02550		-0.3	-1.1	helix-turn-helix transcriptional regulator
MMP_RS08975		-0.3	-1.3	hypothetical protein
MMP_RS07820		-0.3	-1.0	UPF0104 family protein
MMP_RS01525		-0.3	-0.7	nucleoside-diphosphate kinase
MMP_RS08480		-0.3	-1.8	molybdate ABC transporter substrate-binding protein
MMP_RS03680		-0.3	-2.0	hypothetical protein
MMP_RS08840		-0.3	-1.7	class I SAM-dependent methyltransferase
MMP_RS02425		-0.3	-1.2	hypothetical protein
MMP_RS08705		-0.3	-1.6	sulfopyruvate decarboxylase subunit beta
MMP_RS07875		-0.3	-1.0	hypothetical protein
MMP_RS00110		-0.3	-0.7	hypothetical protein
MMP_RS02645		-0.3	-1.5	ArsR family transcriptional regulator
MMP_RS07185		-0.3	-1.7	pyridoxal phosphate-dependent aminotransferase
MMP_RS00395		-0.3	-0.5	MGMT family protein
MMP_RS02915		-0.2	-1.4	amino acid ABC transporter permease
MMP_RS03490		-0.2	-0.6	DUF2115 domain-containing protein
MMP_RS04795		-0.2	-1.7	tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY
MMP_RS00240		-0.2	-1.7	type II secretion system F family protein
MMP_RS07615		-0.2	-1.1	energy-coupling factor ABC transporter permease
MMP_RS00245		-0.2	-2.1	type II secretion system F family protein
MMP_RS06480		-0.2	-1.6	ABC transporter substrate-binding protein
MMP_RS03325		-0.2	-1.7	hypothetical protein
MMP_RS08265		-0.2	-0.8	rubrerythrin
MMP_RS07435		-0.2	-0.5	GMP synthase subunit A
MMP_RS05420		-0.2	-1.0	DUF61 family protein
MMP_RS07125		-0.2	-0.8	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05930		-0.2	-0.6	3-isopropylmalate dehydratase large subunit
MMP_RS00250		-0.2	-2.0	Flp pilus assembly complex ATPase component TadA
MMP_RS01215		-0.2	-1.5	sodium/proline symporter PutP
MMP_RS00940		-0.2	-1.2	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS08470		-0.2	-1.2	ATP-binding cassette domain-containing protein
MMP_RS07425		-0.2	-1.5	GTP-binding protein
MMP_RS03035		-0.2	-1.0	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS03630		-0.2	-1.8	hypothetical protein
MMP_RS06035		-0.2	-1.3	glycosyltransferase family 2 protein
MMP_RS04890		-0.2	-0.3	adenylyltransferase/cytidyltransferase family protein
MMP_RS02705		-0.2	-1.6	formylmethanofuran dehydrogenase subunit B
MMP_RS01575		-0.2	-1.3	aldolase
MMP_RS03615		-0.2	-1.4	4Fe-4S binding protein
MMP_RS01315		-0.2	-2.0	DUF2341 domain-containing protein
MMP_RS00900		-0.2	-0.4	50S ribosomal protein L39e
MMP_RS04475		-0.2	-1.5	nitrogen fixation
MMP_RS05450		-0.2	-0.9	CoB--CoM heterodisulfide reductase subunit C
MMP_RS03115		-0.2	-1.8	hypothetical protein
MMP_RS07915		-0.2	-1.0	DUF4870 domain-containing protein
MMP_RS08995		-0.2	-0.4	hypothetical protein
MMP_RS04165		-0.2	-0.8	TetR/AcrR family transcriptional regulator
MMP_RS00845		-0.2	-1.7	acetate--CoA ligase
MMP_RS04820		-0.2	-1.7	methyl-accepting chemotaxis protein
MMP_RS08855		-0.2	-1.4	hypothetical protein
MMP_RS02360		-0.2	-1.5	hypothetical protein
MMP_RS02020		-0.2	-0.8	gamma-glutamylcyclotransferase
MMP_RS06305		-0.2	-1.2	transporter substrate-binding domain-containing protein
MMP_RS04440		-0.2	-1.7	nitrogenase iron protein
MMP_RS00945		-0.2	-0.4	PadR family transcriptional regulator
MMP_RS01130		-0.2	-1.3	flavoprotein
MMP_RS08355		-0.2	-1.0	Na(+)/H(+) antiporter subunit B
MMP_RS05545		-0.2	-1.0	pyridoxal phosphate-dependent aminotransferase
MMP_RS04145		-0.2	-0.5	hypothetical protein
MMP_RS08890		-0.2	-1.6	glycosyltransferase family 4 protein
MMP_RS02500		-0.2	-1.1	minichromosome maintenance protein MCM
MMP_RS05875		-0.2	-1.0	hydroxyethylthiazole kinase
MMP_RS02880		-0.2	-1.4	AmmeMemoRadiSam system radical SAM enzyme
MMP_RS05950		-0.2	-1.3	nickel-dependent hydrogenase large subunit
MMP_RS06090		-0.2	-1.2	iron ABC transporter permease
MMP_RS02800		-0.2	-1.1	nucleotidyltransferase domain-containing protein
MMP_RS02985		-0.2	-0.7	hypothetical protein
MMP_RS04305		-0.2	-0.6	hypothetical protein
MMP_RS05525		-0.2	-1.0	calcium/sodium antiporter
MMP_RS00325		-0.2	-0.3	RNA-binding protein
MMP_RS00950		-0.2	-1.1	site-2 protease family protein
MMP_RS06770		-0.2	-1.3	DHH family phosphoesterase
MMP_RS03355		-0.2	-1.2	beta-propeller domain-containing protein
MMP_RS03550		-0.2	-0.3	DUF2124 domain-containing protein
MMP_RS06980		-0.2	-1.3	tRNA 2-thiocytidine biosynthesis TtcA family protein
MMP_RS05000		-0.2	-1.5	FmdE family protein
MMP_RS04520		-0.2	-0.5	nucleoside deaminase
MMP_RS01115		-0.2	-1.3	molybdopterin molybdotransferase MoeA
MMP_RS02690		-0.2	-1.1	FmdE family protein
MMP_RS06375		-0.2	-0.9	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS00235		-0.2	-1.1	HDIG domain-containing protein
MMP_RS06585		-0.2	-0.4	DMT family protein
MMP_RS06445		-0.2	-0.9	DUF89 domain-containing protein
MMP_RS07710		-0.2	-1.0	cell division protein FtsZ
MMP_RS00990		-0.2	-1.1	hypothetical protein
MMP_RS02895		-0.2	-1.1	DHH family phosphoesterase
MMP_RS04740		-0.2	-0.9	DUF473 domain-containing protein
MMP_RS08640		-0.2	-1.4	TIM barrel protein
MMP_RS08455		-0.2	-0.6	multiprotein bridging factor aMBF1

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in freezer experiments