Experiment set2IT017 for Pseudomonas fluorescens FW300-N2E2

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m-Inositol carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.6 -7.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -6.5 -7.7 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4826 -6.1 -8.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3751 -5.8 -13.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3630 -5.8 -8.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3782 -5.8 -5.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4047 -5.7 -5.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5006 -5.6 -10.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3839 -5.5 -6.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4279 -5.4 -14.8 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4596 -5.4 -12.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -5.3 -7.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5175 -5.2 -19.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_64 -5.2 -4.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_2258 -5.0 -12.9 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3842 -5.0 -7.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5150 -5.0 -7.5 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2073 -4.8 -7.4 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3752 -4.8 -23.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4048 -4.7 -8.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3253 -4.7 -8.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4752 -4.7 -15.1 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_5176 -4.7 -13.1 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4762 -4.7 -4.4 Biotin synthesis protein BioH compare
Pf6N2E2_3841 -4.6 -7.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4564 -4.6 -11.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3783 -4.5 -7.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4071 -4.5 -6.9 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5177 -4.4 -12.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3610 -4.4 -5.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_77 -4.4 -6.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_2074 -4.3 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5527 -4.2 -4.7 Cold shock protein CspC compare
Pf6N2E2_4278 -4.2 -12.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4797 -4.1 -2.6 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3932 -4.0 -5.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3661 -4.0 -7.6 hypothetical protein compare
Pf6N2E2_4277 -3.9 -10.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_2217 -3.9 -8.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4803 -3.9 -2.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_4759 -3.9 -19.0 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_5156 -3.8 -3.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4372 -3.8 -7.6 FIG00460773: hypothetical protein compare
Pf6N2E2_5014 -3.7 -2.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5723 -3.7 -13.5 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_1381 -3.7 -9.1 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_3252 -3.7 -7.6 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_516 -3.6 -8.0 Inosose isomerase (EC 5.3.99.-) conserved
Pf6N2E2_3940 -3.5 -9.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_523 -3.5 -14.1 Inositol transport system ATP-binding protein conserved
Pf6N2E2_524 -3.4 -13.6 Inositol transport system permease protein conserved
Pf6N2E2_66 -3.4 -7.8 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4638 -3.4 -5.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2186 -3.3 -9.4 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_513 -3.3 -8.0 Myo-inosose-2 dehydratase (EC 4.2.1.44) (from data) conserved
Pf6N2E2_3248 -3.2 -6.2 Probable transmembrane protein compare
Pf6N2E2_4761 -3.2 -11.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_512 -3.2 -15.8 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) (from data) conserved
Pf6N2E2_517 -3.2 -15.5 Epi-inositol hydrolase (EC 3.7.1.-) (from data) conserved
Pf6N2E2_2753 -3.2 -5.5 HtrA protease/chaperone protein compare
Pf6N2E2_518 -3.1 -11.1 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) conserved
Pf6N2E2_4077 -3.0 -3.8 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_302 -3.0 -6.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_50 -2.9 -6.5 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_63 -2.9 -4.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_514 -2.8 -6.5 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) conserved
Pf6N2E2_515 -2.8 -8.0 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) conserved
Pf6N2E2_4764 -2.8 -5.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5160 -2.7 -2.8 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3170 -2.7 -6.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5252 -2.7 -4.0 FIG00956396: hypothetical protein compare
Pf6N2E2_1056 -2.6 -1.5 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_1400 -2.6 -14.6 Sensory box histidine kinase/response regulator compare
Pf6N2E2_5178 -2.6 -3.4 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_5579 -2.6 -6.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3346 -2.4 -9.2 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4631 -2.4 -8.9 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_1402 -2.4 -5.1 hypothetical protein compare
Pf6N2E2_522 -2.3 -3.4 Inositol transport system sugar-binding protein compare
Pf6N2E2_3264 -2.3 -2.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3251 -2.2 -11.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4763 -2.2 -9.7 Biotin synthesis protein BioC compare
Pf6N2E2_5676 -2.2 -3.7 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_2465 -2.2 -6.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_178 -2.2 -1.9 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3941 -2.1 -4.3 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_521 -2.1 -3.3 hypothetical protein compare
Pf6N2E2_3460 -2.0 -2.4 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3349 -2.0 -4.3 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2218 -2.0 -5.5 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4453 -2.0 -15.0 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_248 -1.9 -9.4 hypothetical protein compare
Pf6N2E2_5728 -1.9 -5.8 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3835 -1.9 -4.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_4187 -1.9 -3.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3060 -1.9 -4.4 Outer membrane protein H precursor compare
Pf6N2E2_5553 -1.9 -6.2 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4206 -1.9 -1.6 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4417 -1.9 -5.9 Protein of unknown function DUF484 compare
Pf6N2E2_5780 -1.9 -9.6 Periplasmic protease compare
Pf6N2E2_3942 -1.9 -10.4 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_3984 -1.8 -9.5 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_70 -1.8 -5.5 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_4009 -1.8 -8.8 GGDEF domain protein compare
Pf6N2E2_3770 -1.8 -3.2 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_2189 -1.7 -6.3 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_5103 -1.7 -1.9 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5950 -1.7 -5.4 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_4205 -1.6 -5.2 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_4611 -1.6 -4.9 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4351 -1.5 -8.6 Predicted signal transduction protein compare
Pf6N2E2_2473 -1.5 -1.8 Major outer membrane lipoprotein I compare
Pf6N2E2_4305 -1.5 -1.9 FIG00959590: hypothetical protein compare
Pf6N2E2_1401 -1.5 -4.0 FIG00955631: hypothetical protein compare
Pf6N2E2_2885 -1.4 -7.1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3271 -1.4 -3.2 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_2758 -1.4 -9.8 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_2574 -1.4 -1.6 Flagellar synthesis regulator FleN compare
Pf6N2E2_4049 -1.4 -8.3 Glycine cleavage system transcriptional activator compare
Pf6N2E2_2899 -1.4 -5.4 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_5219 -1.4 -7.5 FIG140336: TPR domain protein compare
Pf6N2E2_1932 -1.4 -5.5 Transcriptional regulator, IclR family compare
Pf6N2E2_2312 -1.4 -1.8 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_5571 -1.4 -2.3 hypothetical protein compare
Pf6N2E2_3938 -1.4 -10.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_4352 -1.4 -2.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3885 -1.3 -2.7 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2514 -1.3 -4.5 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_5155 -1.3 -3.7 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_4773 -1.3 -1.5 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_3062 -1.3 -3.3 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2261 -1.3 -6.6 VacJ-like lipoprotein precursor compare
Pf6N2E2_4369 -1.3 -2.6 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_4476 -1.2 -6.8 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_3300 -1.2 -3.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_4362 -1.2 -3.6 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_51 -1.2 -4.8 hypothetical protein compare
Pf6N2E2_2274 -1.2 -5.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2496 -1.2 -2.4 FIG00956575: hypothetical protein compare
Pf6N2E2_5722 -1.2 -2.8 23S rRNA (Uracil-5-) -methyltransferase RumA (EC 2.1.1.-) ## LSU rRNA m(5)U1939 compare
Pf6N2E2_2219 -1.2 -2.4 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_3039 -1.2 -6.1 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_5666 -1.2 -6.8 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2320 -1.2 -3.5 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_5328 -1.2 -3.5 FIG00958649: hypothetical protein compare
Pf6N2E2_3461 -1.1 -1.7 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_1147 -1.1 -2.1 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) compare
Pf6N2E2_5001 -1.1 -2.0 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5494 -1.1 -3.5 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_4579 -1.1 -1.3 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_4479 -1.1 -2.6 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_4416 -1.1 -1.8 Tyrosine recombinase XerC compare
Pf6N2E2_3270 -1.1 -3.9 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_2586 -1.1 -1.9 Hpt domain protein compare
Pf6N2E2_4160 -1.1 -1.7 Cytochrome c5 compare
Pf6N2E2_309 -1.1 -2.3 FIG00957702: hypothetical protein compare
Pf6N2E2_5190 -1.0 -6.8 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_279 -1.0 -5.1 Isocitrate lyase (EC 4.1.3.1) compare
Pf6N2E2_3534 -1.0 -2.0 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_4204 -1.0 -1.8 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_519 -1.0 -3.1 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) compare
Pf6N2E2_5536 -0.9 -1.4 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3198 -0.9 -1.6 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_2282 -0.9 -3.5 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_3171 -0.9 -1.4 hypothetical protein compare
Pf6N2E2_3933 -0.9 -5.5 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_3516 -0.9 -1.6 Probable transmembrane protein compare
Pf6N2E2_1492 -0.9 -3.1 No significant database matches compare
Pf6N2E2_2756 -0.9 -4.2 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5088 -0.9 -2.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4451 -0.9 -3.9 FIG139438: lipoprotein B compare
Pf6N2E2_3847 -0.9 -2.4 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_3260 -0.8 -4.0 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_4454 -0.8 -3.8 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_4993 -0.8 -2.2 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_2513 -0.8 -3.2 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_3834 -0.8 -4.5 Lipoprotein NlpD compare
Pf6N2E2_3258 -0.8 -2.5 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_2080 -0.8 -1.2 hypothetical protein compare
Pf6N2E2_5520 -0.8 -3.9 Sensory box histidine kinase compare
Pf6N2E2_2927 -0.8 -1.1 Putative signal peptide protein compare
Pf6N2E2_5936 -0.8 -2.1 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_6065 -0.8 -2.0 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_5337 -0.8 -3.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_4414 -0.8 -2.5 FIG00953808: hypothetical protein compare
Pf6N2E2_2503 -0.8 -1.7 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_2510 -0.8 -3.2 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2072 -0.8 -2.0 hypothetical protein compare
Pf6N2E2_16 -0.8 -1.4 hypothetical protein compare
Pf6N2E2_156 -0.8 -1.5 Carbon storage regulator compare
Pf6N2E2_2992 -0.8 -3.5 Regulatory protein RecX compare
Pf6N2E2_2844 -0.8 -3.1 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) compare
Pf6N2E2_5258 -0.8 -4.9 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4273 -0.8 -4.7 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2852 -0.8 -5.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_3505 -0.8 -1.2 Translation initiation factor SUI1-related protein compare
Pf6N2E2_5257 -0.8 -4.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3325 -0.8 -2.5 ABC transporter, ATP-binding protein compare
Pf6N2E2_712 -0.8 -2.8 hypothetical protein compare
Pf6N2E2_2413 -0.8 -1.7 FIG074102: hypothetical protein compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source m-Inositol in Pseudomonas fluorescens FW300-N2E2

For carbon source m-Inositol across organisms