Experiment set2IT014 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium propionate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -6.5 -7.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.5 -4.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3630 -6.5 -6.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3783 -6.3 -6.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4826 -6.2 -7.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_71 -6.1 -5.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4825 -6.0 -9.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4279 -6.0 -12.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_6062 -5.9 -8.1 2-methylcitrate synthase (EC 2.3.3.5) (from data) compare
Pf6N2E2_5176 -5.7 -9.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_6061 -5.7 -6.8 Methylisocitrate lyase (EC 4.1.3.30) (from data) conserved
Pf6N2E2_4047 -5.6 -5.4 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3248 -5.5 -6.1 Probable transmembrane protein compare
Pf6N2E2_3839 -5.5 -6.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5175 -5.3 -17.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3782 -5.3 -6.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3841 -5.2 -6.1 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5177 -5.1 -13.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_6060 -5.1 -3.5 Propionate catabolism operon transcriptional regulator of GntR family [predicted] conserved
Pf6N2E2_3610 -5.1 -7.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5014 -5.0 -1.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3842 -5.0 -6.3 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3253 -4.9 -7.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4278 -4.9 -13.3 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_64 -4.8 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3932 -4.7 -6.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4048 -4.7 -8.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_288 -4.6 -3.2 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_4596 -4.6 -10.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5723 -4.6 -15.0 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4764 -4.4 -8.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5006 -4.4 -9.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4761 -4.4 -11.9 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_2282 -4.3 -6.5 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_4277 -4.3 -10.7 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4762 -4.3 -4.5 Biotin synthesis protein BioH compare
Pf6N2E2_3270 -4.3 -5.8 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_4564 -4.3 -9.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5258 -4.3 -10.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_66 -4.2 -9.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3661 -4.2 -6.9 hypothetical protein compare
Pf6N2E2_5527 -4.1 -4.3 Cold shock protein CspC compare
Pf6N2E2_4759 -4.1 -20.1 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_6063 -4.1 -10.2 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_2217 -4.1 -6.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3460 -4.1 -2.8 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2073 -4.1 -8.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5160 -4.0 -2.0 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_302 -3.9 -7.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5279 -3.9 -5.2 Hypothetical flavoprotein YqcA (clustered with tRNA pseudouridine synthase C) conserved
Pf6N2E2_5153 -3.9 -8.9 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_6064 -3.9 -6.9 2-methylaconitate isomerase compare
Pf6N2E2_5178 -3.8 -2.6 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4803 -3.8 -2.6 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3252 -3.8 -8.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5406 -3.8 -3.6 FIG00958224: hypothetical protein compare
Pf6N2E2_4579 -3.8 -3.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_4638 -3.7 -4.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3940 -3.7 -11.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5156 -3.7 -3.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4763 -3.6 -13.1 Biotin synthesis protein BioC compare
Pf6N2E2_50 -3.6 -9.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3751 -3.5 -14.9 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_2218 -3.4 -5.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4599 -3.4 -5.2 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_3908 -3.4 -9.8 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3666 -3.4 -4.3 InaA protein compare
Pf6N2E2_4071 -3.3 -4.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2753 -3.3 -5.4 HtrA protease/chaperone protein compare
Pf6N2E2_3884 -3.3 -11.1 Histone acetyltransferase HPA2 and related acetyltransferases conserved
Pf6N2E2_5728 -3.3 -6.3 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4187 -3.2 -5.3 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_248 -3.2 -10.5 hypothetical protein compare
Pf6N2E2_2188 -3.2 -6.6 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family compare
Pf6N2E2_3752 -3.2 -18.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4272 -3.2 -6.6 putative membrane protein compare
Pf6N2E2_3612 -3.1 -3.7 HflK protein compare
Pf6N2E2_4072 -3.1 -5.5 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_4631 -3.0 -9.4 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_63 -3.0 -4.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4075 -3.0 -6.6 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_2574 -3.0 -3.4 Flagellar synthesis regulator FleN compare
Pf6N2E2_3611 -3.0 -2.3 HflC protein compare
Pf6N2E2_5520 -3.0 -8.7 Sensory box histidine kinase compare
Pf6N2E2_2261 -3.0 -9.4 VacJ-like lipoprotein precursor compare
Pf6N2E2_3257 -2.9 -6.1 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_5579 -2.9 -7.8 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_1636 -2.9 -11.1 Ferrichrome-iron receptor compare
Pf6N2E2_3170 -2.9 -6.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5257 -2.8 -9.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5950 -2.8 -4.7 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2465 -2.8 -5.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5157 -2.8 -11.0 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2274 -2.8 -5.8 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3667 -2.7 -1.5 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3260 -2.7 -7.6 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_4372 -2.7 -7.6 FIG00460773: hypothetical protein compare
Pf6N2E2_4612 -2.7 -6.6 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_2277 -2.5 -3.1 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5190 -2.5 -11.5 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_178 -2.5 -1.4 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5242 -2.5 -2.8 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2219 -2.4 -2.2 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_1625 -2.4 -4.8 Ferric reductase (1.6.99.14) compare
Pf6N2E2_3183 -2.4 -4.7 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_600 -2.4 -2.7 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_3261 -2.3 -4.7 hypothetical protein compare
Pf6N2E2_2586 -2.3 -3.2 Hpt domain protein compare
Pf6N2E2_4611 -2.3 -3.6 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_4052 -2.2 -2.0 FIG00955481: hypothetical protein compare
Pf6N2E2_2824 -2.2 -10.3 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_1056 -2.2 -1.0 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3258 -2.1 -6.1 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_3251 -2.1 -10.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4800 -2.1 -10.3 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) (from data) conserved
Pf6N2E2_4799 -2.1 -10.6 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) conserved
Pf6N2E2_4453 -2.1 -13.2 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5181 -2.1 -13.0 Paraquat-inducible protein A compare
Pf6N2E2_2010 -2.1 -2.4 hypothetical protein compare
Pf6N2E2_4801 -2.1 -12.8 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) conserved
Pf6N2E2_1626 -2.0 -4.5 Putative ATP-binding component of a transport system compare
Pf6N2E2_3346 -2.0 -7.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_2823 -2.0 -6.0 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_3062 -2.0 -3.2 Membrane-associated zinc metalloprotease compare
Pf6N2E2_424 -1.9 -6.5 Decarboxylase family protein conserved
Pf6N2E2_4120 -1.9 -10.5 Trk system potassium uptake protein TrkA compare
Pf6N2E2_5553 -1.9 -9.1 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_2533 -1.9 -9.5 Rhodanese domain protein UPF0176 conserved
Pf6N2E2_5183 -1.9 -11.6 Paraquat-inducible protein B compare
Pf6N2E2_2258 -1.9 -8.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3984 -1.9 -7.3 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4276 -1.9 -5.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2634 -1.9 -9.1 Potassium uptake protein TrkH compare
Pf6N2E2_2514 -1.9 -4.5 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_4025 -1.9 -1.9 hypothetical protein compare
Pf6N2E2_3770 -1.8 -2.9 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_5567 -1.8 -2.7 Glutamate Aspartate transport ATP-binding protein GltL (TC 3.A.1.3.4) compare
Pf6N2E2_623 -1.8 -1.2 FIG00954674: hypothetical protein compare
Pf6N2E2_5331 -1.8 -8.3 ATPase, AFG1 family compare
Pf6N2E2_4204 -1.8 -1.9 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_4009 -1.8 -7.0 GGDEF domain protein compare
Pf6N2E2_3537 -1.8 -3.7 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_4074 -1.8 -9.5 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_5494 -1.8 -5.4 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_2872 -1.8 -9.1 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_5346 -1.8 -2.9 rRNA small subunit methyltransferase I compare
Pf6N2E2_4418 -1.7 -1.0 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2646 -1.7 -1.4 FIG00953416: hypothetical protein compare
Pf6N2E2_4614 -1.7 -4.1 twitching motility protein PilH compare
Pf6N2E2_5430 -1.7 -9.1 Transglycosylase, Slt family compare
Pf6N2E2_5182 -1.7 -5.7 Paraquat-inducible protein A compare
Pf6N2E2_5111 -1.6 -3.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_3665 -1.6 -1.2 serine/threonine protein kinase compare
Pf6N2E2_6140 -1.6 -1.2 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_4417 -1.6 -4.6 Protein of unknown function DUF484 compare
Pf6N2E2_3264 -1.6 -2.3 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3656 -1.6 -5.1 Probable transcription regulator Mig-14 compare
Pf6N2E2_5538 -1.6 -5.6 4-hydroxybenzoyl-CoA thioesterase family active site compare
Pf6N2E2_5746 -1.6 -1.6 Cobalamin synthase compare
Pf6N2E2_75 -1.6 -3.2 Colicin V production protein compare
Pf6N2E2_2387 -1.6 -4.0 Ribonuclease E inhibitor RraA compare
Pf6N2E2_5155 -1.5 -2.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3037 -1.5 -8.5 RNA polymerase sigma factor RpoS compare
Pf6N2E2_3384 -1.5 -2.5 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_5188 -1.5 -3.9 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5223 -1.5 -3.4 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_367 -1.5 -2.8 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_3103 -1.5 -6.4 Phosphoenolpyruvate carboxylase (EC 4.1.1.31) conserved
Pf6N2E2_2253 -1.5 -2.0 hypothetical protein compare
Pf6N2E2_5671 -1.5 -3.2 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_2200 -1.5 -1.5 RNA polymerase sigma-54 factor RpoN compare
Pf6N2E2_3533 -1.4 -4.0 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_4073 -1.4 -5.5 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
Pf6N2E2_1169 -1.4 -1.9 TnpR protein compare
Pf6N2E2_5536 -1.4 -1.6 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5392 -1.4 -3.5 Molybdenum cofactor biosynthesis protein MoaC compare
Pf6N2E2_2074 -1.4 -1.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3039 -1.4 -5.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_634 -1.4 -6.7 NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form compare
Pf6N2E2_3807 -1.4 -5.3 Histidine utilization repressor compare
Pf6N2E2_5793 -1.4 -5.9 Aspartyl aminopeptidase compare
Pf6N2E2_5745 -1.3 -5.8 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_2640 -1.3 -2.0 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_127 -1.3 -1.8 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_3461 -1.3 -1.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5093 -1.3 -8.6 ATP-dependent protease La (EC 3.4.21.53) Type II compare
Pf6N2E2_4205 -1.3 -3.0 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_3531 -1.3 -4.6 Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_3328 -1.3 -2.1 transcriptional regulator compare
Pf6N2E2_339 -1.3 -3.0 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_3847 -1.3 -3.9 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_3586 -1.3 -5.4 NAD synthetase (EC 6.3.1.5) compare
Pf6N2E2_4511 -1.3 -5.6 glutamine synthetase family protein compare
Pf6N2E2_2068 -1.3 -6.2 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_4150 -1.3 -3.8 probable exported protein YPO0432 compare
Pf6N2E2_5986 -1.3 -2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_233 -1.3 -6.5 Transcriptional regulator, TetR family compare
Pf6N2E2_2825 -1.3 -4.0 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_2065 -1.3 -3.0 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_37 -1.3 -3.2 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare


Specific Phenotypes

For 21 genes in this experiment

For carbon source Sodium propionate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium propionate across organisms