Experiment set2IT013 for Pseudomonas fluorescens FW300-N2E2

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Sodium succinate dibasic hexahydrate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3782 -6.4 -4.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_71 -6.3 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3630 -6.3 -7.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3842 -6.2 -6.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_64 -6.2 -4.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4596 -6.2 -10.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_77 -6.0 -5.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5176 -5.9 -9.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4597 -5.9 -11.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4047 -5.7 -5.6 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4826 -5.7 -9.5 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3253 -5.7 -6.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_5175 -5.6 -18.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3839 -5.5 -6.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4825 -5.5 -11.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3751 -5.2 -16.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_4564 -5.1 -12.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3248 -5.1 -6.2 Probable transmembrane protein compare
Pf6N2E2_5014 -5.1 -2.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3252 -4.7 -10.9 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5177 -4.7 -12.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3752 -4.6 -21.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5707 -4.6 -18.1 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate conserved
Pf6N2E2_3610 -4.5 -8.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3940 -4.5 -13.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4048 -4.4 -7.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -4.4 -7.8 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3251 -4.3 -13.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2074 -4.3 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_66 -4.2 -10.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_2073 -4.2 -9.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2465 -4.1 -10.7 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3783 -4.0 -8.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3883 -3.9 -8.1 C4-dicarboxylate transport transcriptional regulatory protein conserved
Pf6N2E2_302 -3.9 -7.5 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5527 -3.6 -5.4 Cold shock protein CspC compare
Pf6N2E2_4638 -3.3 -5.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_50 -3.3 -7.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3932 -3.3 -4.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3762 -3.0 -10.0 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_5242 -3.0 -2.9 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_5331 -2.9 -10.1 ATPase, AFG1 family compare
Pf6N2E2_5006 -2.9 -11.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4759 -2.9 -16.5 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3170 -2.9 -7.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2277 -2.8 -3.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5111 -2.8 -3.7 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2753 -2.8 -5.4 HtrA protease/chaperone protein compare
Pf6N2E2_5579 -2.7 -6.2 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_2218 -2.7 -6.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4204 -2.5 -2.9 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_5156 -2.4 -4.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_63 -2.4 -4.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3882 -2.3 -5.6 Signal transduction histidine kinase regulating C4-dicarboxylate transport system conserved
Pf6N2E2_4206 -2.3 -3.7 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4762 -2.2 -4.9 Biotin synthesis protein BioH compare
Pf6N2E2_4797 -2.2 -2.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_5728 -2.1 -5.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3984 -1.9 -8.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5666 -1.9 -8.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2217 -1.9 -6.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2473 -1.8 -2.0 Major outer membrane lipoprotein I compare
Pf6N2E2_4761 -1.8 -10.8 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4579 -1.8 -3.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_4009 -1.7 -11.1 GGDEF domain protein compare
Pf6N2E2_4764 -1.7 -4.9 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5667 -1.7 -7.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4071 -1.7 -5.5 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3346 -1.7 -7.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_248 -1.7 -7.9 hypothetical protein compare
Pf6N2E2_4763 -1.6 -9.4 Biotin synthesis protein BioC compare
Pf6N2E2_3349 -1.6 -2.2 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_3835 -1.5 -6.1 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5553 -1.5 -5.9 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_5950 -1.5 -4.9 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_37 -1.5 -3.3 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_2586 -1.5 -2.6 Hpt domain protein compare
Pf6N2E2_5258 -1.4 -7.5 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2514 -1.4 -3.8 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_2318 -1.4 -8.2 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4059 -1.4 -1.7 DNA-binding protein HU-alpha compare
Pf6N2E2_5338 -1.4 -8.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_6140 -1.4 -1.4 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_2675 -1.4 -1.7 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_2320 -1.3 -3.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_4631 -1.3 -7.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3825 -1.3 -5.5 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_4205 -1.3 -4.1 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2310 -1.3 -8.0 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3460 -1.3 -2.1 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2286 -1.3 -3.4 FIG00953287: hypothetical protein compare
Pf6N2E2_4417 -1.3 -3.9 Protein of unknown function DUF484 compare
Pf6N2E2_4159 -1.2 -3.9 Cytochrome c4 compare
Pf6N2E2_5339 -1.2 -5.0 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_3899 -1.2 -6.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5337 -1.1 -3.8 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_5257 -1.1 -6.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5219 -1.1 -6.5 FIG140336: TPR domain protein compare
Pf6N2E2_5103 -1.1 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2527 -1.1 -3.5 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3534 -1.1 -3.0 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_241 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_2886 -1.1 -9.0 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2317 -1.1 -3.2 Putative analog of CcoH, COG3198 compare
Pf6N2E2_5746 -1.1 -2.4 Cobalamin synthase compare
Pf6N2E2_3786 -1.1 -2.6 Twin-arginine translocation protein TatC compare
Pf6N2E2_4352 -1.0 -2.6 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_51 -1.0 -4.2 hypothetical protein compare
Pf6N2E2_2311 -1.0 -5.6 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_2313 -1.0 -3.3 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_2487 -1.0 -1.4 FIG00956090: hypothetical protein compare
Pf6N2E2_4372 -1.0 -4.5 FIG00460773: hypothetical protein compare
Pf6N2E2_3938 -1.0 -6.8 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_5316 -1.0 -2.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3257 -1.0 -3.5 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4454 -1.0 -4.1 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_4601 -1.0 -1.6 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_2340 -1.0 -3.5 Transcriptional regulator, GntR family compare
Pf6N2E2_4162 -1.0 -1.9 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_5676 -1.0 -3.1 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_3826 -0.9 -3.3 Nitrogen regulation protein NR(I) compare
Pf6N2E2_3461 -0.9 -1.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2068 -0.9 -6.0 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_5536 -0.9 -1.6 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3300 -0.9 -3.4 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_434 -0.9 -2.3 hypothetical protein compare
Pf6N2E2_1636 -0.9 -5.4 Ferrichrome-iron receptor compare
Pf6N2E2_2059 -0.9 -1.8 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_5743 -0.9 -4.7 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_1932 -0.9 -3.8 Transcriptional regulator, IclR family compare
Pf6N2E2_2367 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_5155 -0.8 -2.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5508 -0.8 -1.9 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_1288 -0.8 -2.1 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_2064 -0.8 -3.1 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_3763 -0.8 -1.2 hypothetical protein compare
Pf6N2E2_114 -0.8 -2.7 Polysaccharide biosynthesis protein compare
Pf6N2E2_3725 -0.8 -1.7 FIG085779: Lipoprotein compare
Pf6N2E2_1596 -0.8 -1.8 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_4351 -0.8 -5.5 Predicted signal transduction protein compare
Pf6N2E2_2758 -0.8 -6.4 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_2984 -0.8 -2.3 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_3039 -0.8 -4.1 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_3062 -0.8 -3.5 Membrane-associated zinc metalloprotease compare
Pf6N2E2_3885 -0.8 -2.4 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_4416 -0.8 -1.6 Tyrosine recombinase XerC compare
Pf6N2E2_4273 -0.8 -4.5 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5766 -0.8 -1.2 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_613 -0.8 -1.4 lipoprotein, putative compare
Pf6N2E2_4824 -0.8 -2.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_70 -0.8 -3.0 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3072 -0.8 -4.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_5520 -0.8 -3.4 Sensory box histidine kinase compare
Pf6N2E2_1626 -0.8 -3.4 Putative ATP-binding component of a transport system compare
Pf6N2E2_624 -0.8 -3.1 hypothetical protein PA3071 compare
Pf6N2E2_4467 -0.8 -2.5 hypothetical protein compare
Pf6N2E2_1323 -0.8 -1.3 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_3635 -0.8 -2.6 FIG00953138: hypothetical protein compare
Pf6N2E2_2062 -0.7 -1.6 FIG00955561: hypothetical protein compare
Pf6N2E2_3040 -0.7 -4.4 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_4276 -0.7 -3.1 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_3532 -0.7 -4.1 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
Pf6N2E2_5745 -0.7 -3.6 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_1987 -0.7 -0.8 hypothetical protein compare
Pf6N2E2_5261 -0.7 -1.0 FIG00956983: hypothetical protein compare
Pf6N2E2_3713 -0.7 -1.7 Acyl carrier protein compare
Pf6N2E2_3906 -0.7 -5.1 Transcription accessory protein (S1 RNA-binding domain) compare
Pf6N2E2_669 -0.7 -2.8 Nuclease inhibitor compare
Pf6N2E2_99 -0.7 -2.9 hypothetical protein compare
Pf6N2E2_3477 -0.7 -1.3 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_1676 -0.7 -1.4 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_5741 -0.7 -3.4 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_4545 -0.7 -1.7 hypothetical protein compare
Pf6N2E2_178 -0.7 -0.9 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5665 -0.7 -4.0 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2384 -0.7 -2.9 CmpX compare
Pf6N2E2_2124 -0.7 -1.1 Mg(2+) transport ATPase protein C compare
Pf6N2E2_1545 -0.7 -2.9 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_5955 -0.7 -3.1 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_5342 -0.7 -1.3 21 kDa hemolysin precursor compare
Pf6N2E2_3869 -0.7 -5.1 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3744 -0.7 -2.1 General secretion pathway protein F compare
Pf6N2E2_1747 -0.7 -2.3 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
Pf6N2E2_3723 -0.7 -2.8 FIG022199: FAD-binding protein compare
Pf6N2E2_3696 -0.7 -0.8 hypothetical protein compare
Pf6N2E2_2534 -0.7 -3.2 Cell division protein BolA compare
Pf6N2E2_2060 -0.6 -4.6 CobN component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_5500 -0.6 -2.8 MoxR-like ATPases compare
Pf6N2E2_1490 -0.6 -2.0 hypothetical protein compare
Pf6N2E2_5738 -0.6 -4.2 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_2708 -0.6 -2.3 Lactam utilization protein LamB compare
Pf6N2E2_987 -0.6 -1.5 hypothetical protein compare
Pf6N2E2_5430 -0.6 -3.9 Transglycosylase, Slt family compare
Pf6N2E2_6164 -0.6 -1.0 tRNA-Val-TAC compare
Pf6N2E2_89 -0.6 -1.6 hypothetical protein compare
Pf6N2E2_1606 -0.6 -2.5 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2264 -0.6 -1.9 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_1632 -0.6 -2.6 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) compare
Pf6N2E2_5740 -0.6 -3.1 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_4928 -0.6 -1.1 Permeases of the major facilitator superfamily compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Sodium succinate dibasic hexahydrate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium succinate dibasic hexahydrate across organisms