Experiment set2IT012 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium pyruvate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4596 -6.5 -9.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3630 -6.2 -8.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4597 -6.2 -10.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4826 -5.9 -9.1 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3253 -5.8 -6.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_71 -5.8 -7.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4825 -5.6 -11.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_5175 -5.5 -18.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3839 -5.4 -6.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4047 -5.4 -7.4 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -5.3 -6.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5176 -5.1 -12.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5014 -5.1 -2.4 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3751 -4.9 -17.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3248 -4.8 -6.9 Probable transmembrane protein compare
Pf6N2E2_5177 -4.8 -11.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3783 -4.7 -7.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_64 -4.6 -4.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5156 -4.4 -3.0 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3752 -4.3 -21.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_2753 -4.2 -5.7 HtrA protease/chaperone protein compare
Pf6N2E2_77 -4.2 -5.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3782 -4.1 -6.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4564 -4.1 -10.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2073 -4.1 -10.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4048 -4.1 -9.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4279 -4.0 -15.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3940 -3.9 -11.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3842 -3.8 -6.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3252 -3.8 -8.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_4638 -3.8 -5.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_302 -3.7 -8.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3932 -3.7 -5.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4278 -3.7 -14.0 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_66 -3.5 -7.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3610 -3.5 -5.8 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4759 -3.3 -16.5 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_1381 -3.3 -10.5 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_2217 -3.2 -8.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4277 -3.1 -11.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5527 -3.1 -5.5 Cold shock protein CspC compare
Pf6N2E2_2074 -3.0 -2.9 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_1294 -3.0 -5.5 Carbon starvation protein A compare
Pf6N2E2_5006 -2.9 -12.8 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_1296 -2.9 -8.5 DNA-binding response regulator, LuxR family conserved
Pf6N2E2_2465 -2.7 -7.3 Cys regulon transcriptional activator CysB compare
Pf6N2E2_1400 -2.7 -12.4 Sensory box histidine kinase/response regulator compare
Pf6N2E2_2277 -2.7 -3.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5579 -2.6 -6.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_1402 -2.6 -6.4 hypothetical protein compare
Pf6N2E2_50 -2.6 -7.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_63 -2.5 -5.8 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_5666 -2.5 -9.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_1295 -2.5 -7.7 Sensor histidine kinase conserved
Pf6N2E2_4764 -2.4 -9.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5001 -2.3 -2.9 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_3251 -2.3 -11.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1293 -2.3 -4.4 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_3170 -2.2 -5.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4762 -2.2 -5.2 Biotin synthesis protein BioH compare
Pf6N2E2_2320 -2.0 -4.4 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_248 -2.0 -10.0 hypothetical protein compare
Pf6N2E2_4761 -2.0 -11.0 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_4372 -1.8 -6.9 FIG00460773: hypothetical protein compare
Pf6N2E2_4797 -1.8 -2.9 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3984 -1.8 -9.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4009 -1.8 -9.9 GGDEF domain protein compare
Pf6N2E2_4206 -1.8 -3.3 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_5667 -1.8 -8.3 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3349 -1.8 -2.4 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2218 -1.8 -5.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4763 -1.7 -9.8 Biotin synthesis protein BioC compare
Pf6N2E2_5728 -1.7 -4.1 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4631 -1.7 -7.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4417 -1.6 -4.4 Protein of unknown function DUF484 compare
Pf6N2E2_5553 -1.6 -7.4 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4077 -1.5 -3.1 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_2317 -1.5 -5.1 Putative analog of CcoH, COG3198 compare
Pf6N2E2_4803 -1.5 -1.8 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3271 -1.5 -2.5 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_178 -1.5 -1.6 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5252 -1.4 -3.1 FIG00956396: hypothetical protein compare
Pf6N2E2_3942 -1.4 -9.2 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_4579 -1.4 -3.1 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3060 -1.3 -4.5 Outer membrane protein H precursor compare
Pf6N2E2_1932 -1.3 -4.5 Transcriptional regulator, IclR family compare
Pf6N2E2_2186 -1.3 -4.4 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_2514 -1.3 -3.6 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_5676 -1.3 -4.9 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_2318 -1.3 -6.7 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3661 -1.2 -4.6 hypothetical protein compare
Pf6N2E2_5780 -1.2 -7.3 Periplasmic protease compare
Pf6N2E2_1315 -1.2 -2.7 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) compare
Pf6N2E2_5242 -1.2 -2.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2693 -1.2 -2.1 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_3095 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_3039 -1.2 -5.2 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_3611 -1.2 -1.5 HflC protein compare
Pf6N2E2_2313 -1.2 -2.8 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_3835 -1.1 -4.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5153 -1.1 -4.6 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_5849 -1.1 -8.7 large component of pyruvate transporter (actP-like) (from data) conserved
Pf6N2E2_122 -1.1 -1.8 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf6N2E2_2310 -1.1 -7.1 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3938 -1.0 -8.1 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_1401 -1.0 -3.0 FIG00955631: hypothetical protein compare
Pf6N2E2_3240 -1.0 -1.8 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_1596 -1.0 -2.4 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_3346 -1.0 -5.0 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4453 -1.0 -8.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_1717 -1.0 -6.0 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_5219 -1.0 -6.3 FIG140336: TPR domain protein compare
Pf6N2E2_2986 -1.0 -3.6 Transcriptional regulator, LuxR family compare
Pf6N2E2_3282 -1.0 -2.2 FIG005080: Possible exported protein compare
Pf6N2E2_84 -1.0 -2.6 hypothetical protein compare
Pf6N2E2_3713 -1.0 -2.8 Acyl carrier protein compare
Pf6N2E2_4162 -1.0 -2.2 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_2219 -1.0 -1.4 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_6164 -1.0 -1.5 tRNA-Val-TAC compare
Pf6N2E2_4168 -1.0 -4.5 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_2340 -1.0 -3.0 Transcriptional regulator, GntR family compare
Pf6N2E2_3062 -0.9 -2.8 Membrane-associated zinc metalloprotease compare
Pf6N2E2_4165 -0.9 -4.0 Zinc ABC transporter, periplasmic-binding protein ZnuA conserved
Pf6N2E2_5155 -0.9 -2.3 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5080 -0.9 -5.2 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_4205 -0.9 -3.9 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2323 -0.9 -2.7 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_5665 -0.9 -3.7 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2752 -0.9 -5.6 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2586 -0.9 -1.9 Hpt domain protein compare
Pf6N2E2_5950 -0.9 -2.6 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_434 -0.8 -2.1 hypothetical protein compare
Pf6N2E2_3017 -0.8 -3.1 hypothetical protein compare
Pf6N2E2_2574 -0.8 -2.0 Flagellar synthesis regulator FleN compare
Pf6N2E2_724 -0.8 -1.7 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_4057 -0.8 -0.9 lipoprotein, putative compare
Pf6N2E2_6140 -0.8 -1.1 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_51 -0.8 -3.4 hypothetical protein compare
Pf6N2E2_2852 -0.8 -6.3 GGDEF domain/EAL domain protein compare
Pf6N2E2_987 -0.8 -1.9 hypothetical protein compare
Pf6N2E2_1718 -0.8 -2.6 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_5190 -0.8 -5.8 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_3003 -0.8 -2.5 Bacteriophage protein GP46 compare
Pf6N2E2_4276 -0.8 -3.3 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_2176 -0.8 -1.3 Amidases related to nicotinamidase compare
Pf6N2E2_3568 -0.8 -2.2 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_2309 -0.8 -2.2 hypothetical protein compare
Pf6N2E2_5536 -0.8 -1.4 Holliday junction DNA helicase RuvA compare
Pf6N2E2_971 -0.8 -2.3 hypothetical protein compare
Pf6N2E2_405 -0.8 -1.6 hypothetical protein compare
Pf6N2E2_2311 -0.8 -4.7 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_1298 -0.8 -2.7 Xanthine transporter,putative compare
Pf6N2E2_5331 -0.7 -4.0 ATPase, AFG1 family compare
Pf6N2E2_5258 -0.7 -4.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_5406 -0.7 -1.8 FIG00958224: hypothetical protein compare
Pf6N2E2_2513 -0.7 -2.2 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2473 -0.7 -1.1 Major outer membrane lipoprotein I compare
Pf6N2E2_624 -0.7 -4.0 hypothetical protein PA3071 compare
Pf6N2E2_5869 -0.7 -2.3 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_2316 -0.7 -4.6 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation compare
Pf6N2E2_3786 -0.7 -2.1 Twin-arginine translocation protein TatC compare
Pf6N2E2_2984 -0.7 -1.4 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_3906 -0.7 -5.0 Transcription accessory protein (S1 RNA-binding domain) compare
Pf6N2E2_3869 -0.7 -4.8 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_5257 -0.7 -4.6 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3807 -0.7 -2.8 Histidine utilization repressor compare
Pf6N2E2_5894 -0.7 -4.1 Putative threonine efflux protein compare
Pf6N2E2_62 -0.7 -3.2 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4167 -0.7 -4.1 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf6N2E2_2261 -0.7 -3.9 VacJ-like lipoprotein precursor compare
Pf6N2E2_4824 -0.7 -1.9 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_5919 -0.7 -2.1 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_5768 -0.7 -2.0 DNA recombination-dependent growth factor C compare
Pf6N2E2_3027 -0.7 -1.2 Baseplate assembly protein V compare
Pf6N2E2_4181 -0.7 -1.1 Organic hydroperoxide resistance protein compare
Pf6N2E2_5848 -0.7 -2.1 small component of pyruvate transporter (yjcH-like) (from data) compare
Pf6N2E2_3761 -0.7 -6.0 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_170 -0.7 -1.6 lipoprotein, putative compare
Pf6N2E2_3941 -0.7 -2.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3040 -0.7 -3.0 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_4454 -0.7 -3.4 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2717 -0.7 -1.9 putative cytoplasmic protein compare
Pf6N2E2_1776 -0.7 -1.8 Chemotaxis protein CheD compare
Pf6N2E2_342 -0.7 -1.2 DNA-binding response regulator compare
Pf6N2E2_4747 -0.6 -1.4 Transmembrane sensor compare
Pf6N2E2_2534 -0.6 -3.1 Cell division protein BolA compare
Pf6N2E2_3870 -0.6 -1.5 hypothetical protein compare
Pf6N2E2_3340 -0.6 -4.8 Fructose repressor FruR, LacI family compare
Pf6N2E2_1446 -0.6 -2.2 Enoyl-[acyl-carrier-protein] reductase [NADPH] (EC 1.3.1.10) compare
Pf6N2E2_5251 -0.6 -1.6 FIG00954698: hypothetical protein compare
Pf6N2E2_1492 -0.6 -2.6 No significant database matches compare
Pf6N2E2_3840 -0.6 -1.8 FIG00956267: hypothetical protein compare
Pf6N2E2_3257 -0.6 -2.6 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_4423 -0.6 -1.6 FIG00953342: hypothetical protein compare
Pf6N2E2_2674 -0.6 -1.0 FIG00953856: hypothetical protein compare
Pf6N2E2_1584 -0.6 -1.8 Transcriptional regulator, MarR family / Acetyltransferase (GNAT) compare
Pf6N2E2_1806 -0.6 -1.6 hypothetical protein compare
Pf6N2E2_3849 -0.6 -1.3 FIG00954739: hypothetical protein compare
Pf6N2E2_417 -0.6 -1.6 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf6N2E2_3260 -0.6 -2.8 Uncharacterized ABC transporter, ATP-binding protein YrbF compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium pyruvate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium pyruvate across organisms