Experiment set2IT010 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4826 -7.0 -4.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3839 -6.4 -4.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3630 -6.2 -7.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3751 -6.0 -12.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_71 -6.0 -7.1 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_77 -5.9 -5.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_4597 -5.7 -10.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3253 -5.6 -6.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_5176 -5.5 -11.2 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5175 -5.4 -17.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4825 -5.3 -11.4 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_4596 -5.3 -11.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4047 -5.2 -7.1 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3384 -5.1 -6.9 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3610 -5.0 -4.9 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3842 -4.9 -6.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4279 -4.8 -15.7 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3783 -4.8 -7.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4759 -4.6 -17.3 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4048 -4.5 -7.9 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3381 -4.5 -8.1 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_3841 -4.5 -8.1 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3382 -4.5 -10.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3932 -4.5 -7.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3383 -4.5 -8.2 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_64 -4.3 -5.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3252 -4.3 -9.7 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5527 -4.3 -5.0 Cold shock protein CspC compare
Pf6N2E2_2074 -4.2 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3752 -4.2 -20.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4564 -4.1 -9.0 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4278 -4.1 -13.5 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3251 -4.1 -13.4 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3248 -4.0 -8.1 Probable transmembrane protein compare
Pf6N2E2_3380 -4.0 -11.6 L-lactate permease compare
Pf6N2E2_4764 -4.0 -9.1 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_5177 -4.0 -10.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_63 -3.9 -6.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_66 -3.8 -8.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3940 -3.8 -10.6 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2073 -3.7 -9.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4277 -3.7 -10.7 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3782 -3.5 -5.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4763 -3.4 -11.8 Biotin synthesis protein BioC compare
Pf6N2E2_5156 -3.4 -4.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2465 -3.3 -8.9 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4638 -3.2 -5.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_2753 -3.2 -5.3 HtrA protease/chaperone protein compare
Pf6N2E2_4761 -3.1 -12.3 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_50 -3.1 -8.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_302 -3.1 -7.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4762 -2.9 -4.6 Biotin synthesis protein BioH compare
Pf6N2E2_5666 -2.9 -11.5 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3170 -2.8 -7.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5728 -2.8 -4.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5579 -2.8 -7.1 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4797 -2.8 -3.0 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2277 -2.7 -3.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5006 -2.4 -8.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4631 -2.4 -7.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4418 -2.3 -1.5 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_5667 -2.2 -10.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_248 -2.0 -9.4 hypothetical protein compare
Pf6N2E2_3349 -1.9 -3.1 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2488 -1.8 -2.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4372 -1.8 -6.8 FIG00460773: hypothetical protein compare
Pf6N2E2_4987 -1.8 -1.4 MaoC-like domain protein compare
Pf6N2E2_2217 -1.7 -6.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3460 -1.7 -2.6 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2534 -1.7 -3.5 Cell division protein BolA compare
Pf6N2E2_3984 -1.7 -8.5 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2674 -1.6 -1.9 FIG00953856: hypothetical protein compare
Pf6N2E2_4009 -1.6 -8.1 GGDEF domain protein compare
Pf6N2E2_5014 -1.6 -1.9 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3346 -1.5 -5.8 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_5316 -1.5 -1.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2473 -1.5 -1.8 Major outer membrane lipoprotein I compare
Pf6N2E2_4579 -1.5 -1.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_178 -1.5 -1.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_3938 -1.5 -10.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2218 -1.5 -4.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_51 -1.4 -5.0 hypothetical protein compare
Pf6N2E2_5553 -1.4 -8.1 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4071 -1.4 -5.3 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3661 -1.4 -4.0 hypothetical protein compare
Pf6N2E2_3835 -1.4 -4.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_5252 -1.4 -2.9 FIG00956396: hypothetical protein compare
Pf6N2E2_5190 -1.4 -9.1 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_84 -1.3 -2.8 hypothetical protein compare
Pf6N2E2_4039 -1.3 -6.1 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_2320 -1.3 -3.2 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_5258 -1.2 -6.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4417 -1.2 -4.5 Protein of unknown function DUF484 compare
Pf6N2E2_5676 -1.2 -4.4 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5950 -1.2 -3.2 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_5257 -1.2 -6.0 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2586 -1.2 -1.3 Hpt domain protein compare
Pf6N2E2_2986 -1.2 -3.5 Transcriptional regulator, LuxR family compare
Pf6N2E2_737 -1.1 -1.9 Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) compare
Pf6N2E2_2480 -1.1 -2.2 FIG00957636: hypothetical protein compare
Pf6N2E2_5103 -1.1 -1.6 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2514 -1.1 -2.8 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_3665 -1.1 -1.2 serine/threonine protein kinase compare
Pf6N2E2_2258 -1.1 -7.3 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3015 -1.1 -1.7 hypothetical protein compare
Pf6N2E2_3899 -1.1 -5.4 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_4969 -1.1 -1.5 hypothetical protein compare
Pf6N2E2_5936 -1.0 -2.5 Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48) compare
Pf6N2E2_5219 -1.0 -6.6 FIG140336: TPR domain protein compare
Pf6N2E2_5520 -1.0 -5.0 Sensory box histidine kinase compare
Pf6N2E2_2317 -1.0 -3.2 Putative analog of CcoH, COG3198 compare
Pf6N2E2_4451 -1.0 -4.9 FIG139438: lipoprotein B compare
Pf6N2E2_5499 -1.0 -1.5 hypothetical protein compare
Pf6N2E2_89 -1.0 -2.4 hypothetical protein compare
Pf6N2E2_4476 -1.0 -4.7 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_3062 -1.0 -3.1 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2186 -1.0 -3.7 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3557 -1.0 -3.4 Chaperone-modulator protein CbpM compare
Pf6N2E2_1288 -1.0 -2.7 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_3257 -1.0 -3.0 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3533 -1.0 -4.1 Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) compare
Pf6N2E2_4601 -1.0 -2.2 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_342 -1.0 -1.5 DNA-binding response regulator compare
Pf6N2E2_3039 -0.9 -4.9 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_2062 -0.9 -2.7 FIG00955561: hypothetical protein compare
Pf6N2E2_5746 -0.9 -2.9 Cobalamin synthase compare
Pf6N2E2_2693 -0.9 -1.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_1545 -0.9 -4.0 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_2527 -0.9 -3.5 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_1676 -0.9 -2.6 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_3720 -0.9 -3.0 FIG027190: Putative transmembrane protein compare
Pf6N2E2_3537 -0.9 -3.6 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_3738 -0.9 -2.9 General secretion pathway protein L compare
Pf6N2E2_2313 -0.9 -3.0 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_1717 -0.9 -5.8 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_504 -0.9 -2.2 DNA-binding response regulator compare
Pf6N2E2_309 -0.9 -1.1 FIG00957702: hypothetical protein compare
Pf6N2E2_2318 -0.9 -5.3 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3607 -0.9 -4.5 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_4187 -0.9 -2.3 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_724 -0.9 -2.0 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_5153 -0.9 -4.0 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_3529 -0.9 -1.7 Toxin A compare
Pf6N2E2_4206 -0.9 -1.6 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_70 -0.9 -2.5 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_4040 -0.9 -6.8 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf6N2E2_3687 -0.8 -3.3 FIG00959437: hypothetical protein compare
Pf6N2E2_4454 -0.8 -4.1 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_6140 -0.8 -1.0 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_1932 -0.8 -3.8 Transcriptional regulator, IclR family compare
Pf6N2E2_5342 -0.8 -2.6 21 kDa hemolysin precursor compare
Pf6N2E2_2311 -0.8 -5.1 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_2068 -0.8 -4.9 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_3534 -0.8 -1.1 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_4360 -0.8 -5.7 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_1718 -0.8 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_2447 -0.8 -4.7 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5669 -0.8 -4.3 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_4038 -0.8 -5.1 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_5605 -0.8 -2.5 FxsA protein compare
Pf6N2E2_3869 -0.8 -5.1 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_3283 -0.8 -3.9 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_5679 -0.8 -3.6 hypothetical protein compare
Pf6N2E2_1136 -0.8 -2.0 Transcriptional regulator, TetR family compare
Pf6N2E2_3040 -0.8 -4.2 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_2984 -0.8 -2.1 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_4205 -0.8 -3.2 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2413 -0.8 -1.4 FIG074102: hypothetical protein compare
Pf6N2E2_4537 -0.8 -2.2 Type III secretion inner membrane protein (YscS,homologous to flagellar export components) compare
Pf6N2E2_2389 -0.8 -5.4 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_971 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_659 -0.7 -1.8 Transcriptional regulatory protein ompR compare
Pf6N2E2_2103 -0.7 -2.7 hypothetical protein compare
Pf6N2E2_3325 -0.7 -2.4 ABC transporter, ATP-binding protein compare
Pf6N2E2_613 -0.7 -1.3 lipoprotein, putative compare
Pf6N2E2_5406 -0.7 -2.2 FIG00958224: hypothetical protein compare
Pf6N2E2_1636 -0.7 -4.9 Ferrichrome-iron receptor compare
Pf6N2E2_4743 -0.7 -1.0 hypothetical protein compare
Pf6N2E2_5536 -0.7 -1.1 Holliday junction DNA helicase RuvA compare
Pf6N2E2_2756 -0.7 -4.0 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2310 -0.7 -4.9 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_3947 -0.7 -1.9 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_3807 -0.7 -2.5 Histidine utilization repressor compare
Pf6N2E2_754 -0.7 -1.7 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_5955 -0.7 -3.5 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_5766 -0.7 -1.0 Quaternary ammonium compound-resistance protein SugE compare
Pf6N2E2_3120 -0.7 -3.4 Chemotaxis signal transduction protein compare
Pf6N2E2_2059 -0.7 -2.6 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_2189 -0.7 -3.0 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_5155 -0.7 -2.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_4453 -0.7 -5.8 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_3667 -0.7 -1.0 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_5748 -0.7 -2.0 Transcriptional activator protein LuxR compare
Pf6N2E2_3762 -0.7 -3.5 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_3260 -0.7 -3.4 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2282 -0.7 -2.9 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_1248 -0.7 -1.5 MutT/nudix family protein compare
Pf6N2E2_2499 -0.7 -1.7 Competence protein ComEA helix-hairpin-helix region precursor compare
Pf6N2E2_1797 -0.7 -1.6 Transcriptional regulator compare
Pf6N2E2_2286 -0.7 -1.6 FIG00953287: hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source Sodium L-Lactate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium L-Lactate across organisms