Experiment set2IT009 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium D-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3384 -6.6 -4.5 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_4596 -6.2 -9.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3248 -5.7 -7.2 Probable transmembrane protein compare
Pf6N2E2_5175 -5.3 -17.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3842 -5.3 -7.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3841 -5.3 -6.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4825 -5.2 -11.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_77 -5.2 -7.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_64 -5.2 -4.9 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3839 -5.1 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_71 -5.1 -9.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5177 -5.0 -11.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4826 -5.0 -10.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4597 -4.9 -12.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4047 -4.8 -8.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_5176 -4.8 -12.8 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3381 -4.8 -11.0 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_4278 -4.7 -13.8 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3751 -4.7 -16.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3383 -4.5 -8.3 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3253 -4.5 -8.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3940 -4.4 -13.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3630 -4.4 -8.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4048 -4.3 -9.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5156 -4.3 -3.0 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3932 -4.3 -5.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2073 -4.3 -9.8 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3782 -4.2 -7.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4279 -4.2 -15.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3385 -4.2 -15.5 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing conserved
Pf6N2E2_3752 -4.1 -21.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4759 -4.1 -17.1 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_4564 -4.1 -7.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4797 -4.1 -2.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3783 -4.0 -7.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3610 -3.9 -5.8 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3382 -3.9 -7.0 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_2753 -3.8 -6.3 HtrA protease/chaperone protein compare
Pf6N2E2_3380 -3.8 -10.4 L-lactate permease compare
Pf6N2E2_5014 -3.7 -2.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_302 -3.6 -7.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5527 -3.5 -3.3 Cold shock protein CspC compare
Pf6N2E2_66 -3.4 -8.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4761 -3.3 -14.2 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_63 -3.2 -4.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4277 -3.2 -9.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3252 -3.2 -7.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5579 -3.1 -8.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4638 -3.0 -5.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_5666 -2.9 -11.8 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2277 -2.9 -3.9 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2074 -2.9 -2.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4762 -2.8 -5.3 Biotin synthesis protein BioH compare
Pf6N2E2_3251 -2.8 -12.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4763 -2.7 -11.2 Biotin synthesis protein BioC compare
Pf6N2E2_5006 -2.6 -9.9 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_2534 -2.6 -7.6 Cell division protein BolA compare
Pf6N2E2_3170 -2.6 -7.4 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4631 -2.4 -8.7 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4764 -2.4 -6.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2465 -2.3 -5.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4165 -2.3 -7.0 Zinc ABC transporter, periplasmic-binding protein ZnuA conserved
Pf6N2E2_5667 -2.2 -8.0 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_2217 -2.2 -7.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_50 -2.2 -8.3 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3984 -2.0 -11.1 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_5728 -2.0 -6.4 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_309 -1.9 -3.3 FIG00957702: hypothetical protein compare
Pf6N2E2_2693 -1.9 -2.2 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2313 -1.9 -4.4 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_248 -1.8 -9.1 hypothetical protein compare
Pf6N2E2_2310 -1.8 -10.4 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf6N2E2_4009 -1.8 -10.3 GGDEF domain protein compare
Pf6N2E2_4372 -1.8 -6.2 FIG00460773: hypothetical protein compare
Pf6N2E2_1705 -1.8 -2.6 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_3460 -1.7 -2.5 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2311 -1.7 -8.7 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf6N2E2_3938 -1.7 -12.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_4168 -1.7 -7.3 Zinc ABC transporter, inner membrane permease protein ZnuB compare
Pf6N2E2_3941 -1.6 -4.2 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_1932 -1.6 -6.9 Transcriptional regulator, IclR family compare
Pf6N2E2_5258 -1.6 -7.6 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3183 -1.6 -4.1 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_4204 -1.5 -1.4 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_2318 -1.5 -8.0 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4159 -1.5 -4.8 Cytochrome c4 compare
Pf6N2E2_3349 -1.5 -2.5 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2317 -1.5 -5.5 Putative analog of CcoH, COG3198 compare
Pf6N2E2_2286 -1.5 -3.9 FIG00953287: hypothetical protein compare
Pf6N2E2_4206 -1.4 -2.5 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2514 -1.4 -4.3 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_1381 -1.4 -6.5 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5252 -1.4 -2.5 FIG00956396: hypothetical protein compare
Pf6N2E2_3869 -1.4 -7.7 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_5155 -1.3 -3.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_5676 -1.3 -3.7 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5316 -1.3 -2.3 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_2574 -1.3 -2.7 Flagellar synthesis regulator FleN compare
Pf6N2E2_3062 -1.3 -4.1 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2218 -1.3 -4.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2675 -1.3 -1.6 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_4464 -1.3 -2.4 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_3661 -1.2 -4.3 hypothetical protein compare
Pf6N2E2_2320 -1.2 -3.3 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3835 -1.2 -4.6 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_2527 -1.2 -4.5 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_5190 -1.2 -7.9 Carbonic anhydrase (EC 4.2.1.1) compare
Pf6N2E2_2219 -1.2 -2.5 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_4205 -1.2 -3.5 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_2186 -1.2 -5.4 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3221 -1.2 -4.1 FIG00352444: hypothetical protein compare
Pf6N2E2_3534 -1.2 -2.7 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_2756 -1.2 -5.8 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_3039 -1.2 -6.4 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_1402 -1.2 -5.7 hypothetical protein compare
Pf6N2E2_5257 -1.1 -6.1 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5679 -1.1 -3.6 hypothetical protein compare
Pf6N2E2_5219 -1.1 -6.9 FIG140336: TPR domain protein compare
Pf6N2E2_4167 -1.1 -5.6 Zinc ABC transporter, ATP-binding protein ZnuC compare
Pf6N2E2_237 -1.1 -3.3 hypothetical protein compare
Pf6N2E2_3899 -1.1 -6.7 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_51 -1.1 -4.8 hypothetical protein compare
Pf6N2E2_1400 -1.0 -7.1 Sensory box histidine kinase/response regulator compare
Pf6N2E2_3346 -1.0 -4.8 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4417 -1.0 -4.0 Protein of unknown function DUF484 compare
Pf6N2E2_2674 -1.0 -1.4 FIG00953856: hypothetical protein compare
Pf6N2E2_2065 -1.0 -2.8 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2309 -1.0 -1.6 hypothetical protein compare
Pf6N2E2_5955 -1.0 -2.8 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_712 -1.0 -3.3 hypothetical protein compare
Pf6N2E2_5553 -0.9 -4.9 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_4476 -0.9 -5.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_4071 -0.9 -3.3 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2473 -0.9 -1.3 Major outer membrane lipoprotein I compare
Pf6N2E2_6095 -0.9 -2.3 tRNA-Asn-GTT compare
Pf6N2E2_4360 -0.9 -6.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_2752 -0.9 -5.8 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_2586 -0.9 -1.2 Hpt domain protein compare
Pf6N2E2_70 -0.9 -3.1 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2503 -0.9 -1.9 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_4063 -0.9 -3.0 Chorismate--pyruvate lyase (EC 4.1.3.40) compare
Pf6N2E2_3325 -0.9 -2.7 ABC transporter, ATP-binding protein compare
Pf6N2E2_5665 -0.9 -3.6 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_3713 -0.9 -2.4 Acyl carrier protein compare
Pf6N2E2_6035 -0.9 -1.2 alpha/beta hydrolase fold compare
Pf6N2E2_2488 -0.8 -1.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3807 -0.8 -3.2 Histidine utilization repressor compare
Pf6N2E2_434 -0.8 -2.7 hypothetical protein compare
Pf6N2E2_2068 -0.8 -5.1 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_2588 -0.8 -2.8 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3762 -0.8 -3.8 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_5669 -0.8 -3.9 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_3040 -0.8 -4.0 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_5646 -0.8 -1.1 PROBABLE MEMBRANE PROTEIN compare
Pf6N2E2_5768 -0.8 -2.5 DNA recombination-dependent growth factor C compare
Pf6N2E2_3537 -0.8 -3.5 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_2986 -0.8 -2.2 Transcriptional regulator, LuxR family compare
Pf6N2E2_5001 -0.8 -1.8 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_595 -0.8 -1.4 Arsenical resistance operon repressor compare
Pf6N2E2_4454 -0.8 -3.7 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2389 -0.8 -5.3 Phosphoenolpyruvate synthase (EC 2.7.9.2) compare
Pf6N2E2_2080 -0.8 -1.2 hypothetical protein compare
Pf6N2E2_146 -0.8 -1.4 Transcriptional regulator, MarR family compare
Pf6N2E2_4273 -0.8 -4.3 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5508 -0.8 -1.5 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_5742 -0.8 -4.3 Cobyric acid synthase (EC 6.3.5.10) compare
Pf6N2E2_5520 -0.8 -4.0 Sensory box histidine kinase compare
Pf6N2E2_3568 -0.8 -1.5 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_2390 -0.7 -1.9 FIG00959101: hypothetical protein compare
Pf6N2E2_2459 -0.7 -1.3 Organic hydroperoxide resistance protein compare
Pf6N2E2_5738 -0.7 -4.0 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_5740 -0.7 -3.3 Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) compare
Pf6N2E2_5745 -0.7 -4.2 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_5780 -0.7 -4.8 Periplasmic protease compare
Pf6N2E2_5950 -0.7 -2.2 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_1401 -0.7 -3.4 FIG00955631: hypothetical protein compare
Pf6N2E2_4541 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_2496 -0.7 -1.6 FIG00956575: hypothetical protein compare
Pf6N2E2_2176 -0.7 -1.6 Amidases related to nicotinamidase compare
Pf6N2E2_5986 -0.7 -1.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_5342 -0.7 -2.2 21 kDa hemolysin precursor compare
Pf6N2E2_2552 -0.7 -3.1 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_2010 -0.7 -1.1 hypothetical protein compare
Pf6N2E2_3607 -0.7 -4.1 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_2518 -0.7 -2.0 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_5345 -0.7 -3.6 LppC putative lipoprotein compare
Pf6N2E2_1912 -0.7 -2.9 hypothetical protein compare
Pf6N2E2_65 -0.7 -2.5 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf6N2E2_2794 -0.7 -0.9 putative membrane protein compare
Pf6N2E2_4467 -0.7 -2.6 hypothetical protein compare
Pf6N2E2_2447 -0.7 -2.7 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_1717 -0.7 -4.6 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_1834 -0.7 -1.2 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_2316 -0.7 -4.8 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation compare
Pf6N2E2_1116 -0.6 -1.5 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_1660 -0.6 -2.1 RND efflux system, membrane fusion protein CmeA compare
Pf6N2E2_5328 -0.6 -2.8 FIG00958649: hypothetical protein compare
Pf6N2E2_2166 -0.6 -4.1 protein of unknown function DUF6, transmembrane compare
Pf6N2E2_1759 -0.6 -2.5 uncharacterized domain 1 compare
Pf6N2E2_2059 -0.6 -2.4 ChlI component of cobalt chelatase involved in B12 biosynthesis compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium D-Lactate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium D-Lactate across organisms