Experiment set2IT009 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Sodium D-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_1981 +1.5 6.4 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_2707 +1.4 7.2 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_2438 +1.4 3.6 hypothetical protein compare
Pf6N2E2_3612 +1.3 3.2 HflK protein compare
Pf6N2E2_5720 +1.2 9.7 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_3037 +1.2 9.2 RNA polymerase sigma factor RpoS compare
Pf6N2E2_204 +1.2 1.9 hypothetical protein compare
Pf6N2E2_2022 +1.1 6.8 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_144 +1.1 9.9 Uncharacterized protein YtfM precursor compare
Pf6N2E2_145 +1.0 7.1 putative exported protein compare
Pf6N2E2_3249 +1.0 6.7 Zn-dependent protease with chaperone function compare
Pf6N2E2_902 +1.0 2.4 hypothetical protein compare
Pf6N2E2_4362 +1.0 4.2 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_1450 +1.0 2.4 FIG00960438: hypothetical protein compare
Pf6N2E2_3667 +1.0 1.5 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3373 +0.9 1.9 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_1056 +0.9 1.4 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3659 +0.9 4.8 Protein fixF compare
Pf6N2E2_4943 +0.9 3.7 PspA/IM30 family protein compare
Pf6N2E2_5894 +0.9 6.3 Putative threonine efflux protein compare
Pf6N2E2_2175 +0.9 3.1 Transcriptional regulator, RpiR family compare
Pf6N2E2_3696 +0.9 1.6 hypothetical protein compare
Pf6N2E2_6047 +0.9 2.1 hypothetical protein compare
Pf6N2E2_1043 +0.9 2.4 Transcriptional regulator, IclR family compare
Pf6N2E2_3969 +0.9 1.1 Membrane-fusion protein compare
Pf6N2E2_2223 +0.9 1.7 hypothetical protein compare
Pf6N2E2_1683 +0.8 2.9 Fe2+-dicitrate sensor, membrane component compare
Pf6N2E2_2441 +0.8 4.3 putative ATP/GTP-binding protein compare
Pf6N2E2_4153 +0.8 1.0 Sensory box histidine kinase compare
Pf6N2E2_5899 +0.8 5.0 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_1534 +0.8 1.5 Probable transmembrane protein compare
Pf6N2E2_5531 +0.8 3.8 hypothetical protein compare
Pf6N2E2_4414 +0.8 1.7 FIG00953808: hypothetical protein compare
Pf6N2E2_546 +0.8 1.7 FIG00966904: hypothetical protein compare
Pf6N2E2_3270 +0.8 4.1 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_4084 +0.8 5.0 Transcriptional regulator compare
Pf6N2E2_1656 +0.7 2.0 hypothetical protein compare
Pf6N2E2_3461 +0.7 1.4 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2708 +0.7 3.1 Lactam utilization protein LamB compare
Pf6N2E2_241 +0.7 1.5 hypothetical protein compare
Pf6N2E2_5874 +0.7 6.7 TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins compare
Pf6N2E2_5704 +0.7 4.5 Transcriptional regulatory protein PhoP compare
Pf6N2E2_4708 +0.7 2.6 hypothetical protein compare
Pf6N2E2_2706 +0.7 2.4 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_1032 +0.7 1.3 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_570 +0.7 2.2 DNA-3-methyladenine glycosylase II (EC 3.2.2.21) compare
Pf6N2E2_1095 +0.7 0.9 Opine oxidase subunit C compare
Pf6N2E2_3658 +0.7 4.8 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4148 +0.7 5.0 Glutamate-aspartate carrier protein compare
Pf6N2E2_3122 +0.7 1.4 Chemotaxis signal transduction protein compare
Pf6N2E2_2178 +0.7 3.6 FIG00960144: hypothetical protein compare
Pf6N2E2_5020 +0.7 3.5 FIG00955339: hypothetical protein compare
Pf6N2E2_3617 +0.7 2.5 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_3981 +0.7 6.1 T1SS secreted agglutinin RTX compare
Pf6N2E2_5128 +0.7 2.9 COG1496: Uncharacterized conserved protein compare
Pf6N2E2_5133 +0.7 2.4 FIG00953980: hypothetical protein compare
Pf6N2E2_4733 +0.7 1.6 hypothetical protein compare
Pf6N2E2_827 +0.7 1.7 probable dioxygenase compare
Pf6N2E2_5794 +0.6 1.2 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_82 +0.6 1.8 hypothetical protein compare
Pf6N2E2_5243 +0.6 1.8 hypothetical protein compare
Pf6N2E2_4555 +0.6 4.7 Lysophospholipase (EC 3.1.1.5) compare
Pf6N2E2_4803 +0.6 1.4 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_1325 +0.6 2.7 FIG00954773: hypothetical protein compare
Pf6N2E2_5902 +0.6 1.7 hypothetical protein compare
Pf6N2E2_1273 +0.6 2.8 Probable RND efflux membrane fusion protein compare
Pf6N2E2_750 +0.6 2.4 Transcriptional regulator, DeoR family compare
Pf6N2E2_3134 +0.6 1.0 hypothetical protein compare
Pf6N2E2_6057 +0.6 2.4 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf6N2E2_6058 +0.6 3.6 FIG139976: hypothetical protein compare
Pf6N2E2_2278 +0.6 5.2 Transcription-repair coupling factor compare
Pf6N2E2_924 +0.6 1.3 Transcriptional regulator XdhR, TetR family compare
Pf6N2E2_3978 +0.6 5.0 Type I secretion system, membrane fusion protein LapC compare
Pf6N2E2_5906 +0.6 2.5 Flp pilus assembly protein, pilin Flp compare
Pf6N2E2_2274 +0.6 3.5 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3829 +0.6 3.0 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_2702 +0.6 2.8 FIG00962464: hypothetical protein compare
Pf6N2E2_495 +0.6 2.4 YD repeat protein compare
Pf6N2E2_6018 +0.6 2.6 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_2225 +0.6 1.6 FIG00953489: hypothetical protein compare
Pf6N2E2_1083 +0.6 1.7 hypothetical protein compare
Pf6N2E2_2352 +0.6 1.9 Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) compare
Pf6N2E2_6164 +0.6 1.2 tRNA-Val-TAC compare
Pf6N2E2_3569 +0.6 1.5 hypothetical protein compare
Pf6N2E2_5394 +0.6 2.6 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_5807 +0.6 2.6 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare
Pf6N2E2_5816 +0.6 1.0 Smr domain protein compare
Pf6N2E2_4963 +0.6 1.2 Homoserine dehydrogenase (EC 1.1.1.3) compare
Pf6N2E2_3516 +0.6 1.4 Probable transmembrane protein compare
Pf6N2E2_4635 +0.6 3.5 ATP-dependent RNA helicase RhlE compare
Pf6N2E2_289 +0.6 4.6 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_3979 +0.6 4.5 Type I secretion system ATPase, LssB family LapB compare
Pf6N2E2_2578 +0.6 2.0 Flagellar biosynthesis protein FliR compare
Pf6N2E2_1617 +0.5 1.0 COG2199: FOG: GGDEF domain compare
Pf6N2E2_1299 +0.5 1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_5873 +0.5 3.4 FIG00953467: hypothetical protein compare
Pf6N2E2_1040 +0.5 1.3 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_5761 +0.5 1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_445 +0.5 3.0 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf6N2E2_1783 +0.5 1.3 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_3737 +0.5 1.8 General secretion pathway protein M compare
Pf6N2E2_3271 +0.5 1.2 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_5943 +0.5 1.9 hypothetical protein compare
Pf6N2E2_92 +0.5 1.5 hypothetical protein compare
Pf6N2E2_482 +0.5 1.5 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_4585 +0.5 4.5 Cell division protein FtsX compare
Pf6N2E2_3942 +0.5 4.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_2106 +0.5 1.4 hypothetical protein compare
Pf6N2E2_605 +0.5 1.6 FIG002465: BNR repeat protein compare
Pf6N2E2_395 +0.5 1.9 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_5049 +0.5 1.0 acetyltransferase, GNAT family compare
Pf6N2E2_1774 +0.5 0.7 DNA-binding response regulator, LuxR family, near polyamine transporter compare
Pf6N2E2_3475 +0.5 1.4 hypothetical protein compare
Pf6N2E2_2710 +0.5 2.3 FIG00953701: hypothetical protein compare
Pf6N2E2_122 +0.5 1.2 Tyrosine-protein kinase Wzc (EC 2.7.10.2) compare
Pf6N2E2_723 +0.5 2.1 FIG138517: Putative lipid carrier protein compare
Pf6N2E2_942 +0.5 1.2 Mll6465 protein compare
Pf6N2E2_1403 +0.5 2.0 Nitrous oxide reductase maturation protein, outer-membrane lipoprotein NosL compare
Pf6N2E2_2887 +0.5 1.6 Aldose 1-epimerase compare
Pf6N2E2_5695 +0.5 2.9 Flagellar basal-body rod protein FlgC compare
Pf6N2E2_3338 +0.5 1.1 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_5697 +0.5 4.3 Flagellar hook protein FlgE compare
Pf6N2E2_5882 +0.5 2.7 Putative membrane protein compare
Pf6N2E2_3611 +0.5 1.0 HflC protein compare
Pf6N2E2_2792 +0.5 2.3 Antitoxin 1 compare
Pf6N2E2_4029 +0.5 2.9 Biofilm PGA synthesis N-glycosyltransferase PgaC (EC 2.4.-.-) compare
Pf6N2E2_1840 +0.5 2.2 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_3452 +0.5 3.0 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) compare
Pf6N2E2_3539 +0.5 1.9 FIG00955840: hypothetical protein compare
Pf6N2E2_2477 +0.5 0.8 ABC transporter ATP-binding protein YvcR compare
Pf6N2E2_3980 +0.5 3.8 Type I secretion system, outer membrane component LapE compare
Pf6N2E2_1110 +0.5 2.0 FIG00964414: hypothetical protein compare
Pf6N2E2_4270 +0.5 3.4 putative Glutathione-regulated potassium-efflux system protein KefB compare
Pf6N2E2_6077 +0.5 2.7 Cysteine desulfurase (EC 2.8.1.7) compare
Pf6N2E2_2790 +0.5 1.7 Helix-turn-helix motif compare
Pf6N2E2_5872 +0.5 3.0 Sensor histidine kinase/response regulator compare
Pf6N2E2_5799 +0.5 3.1 Patatin compare
Pf6N2E2_2580 +0.5 1.6 Flagellar biosynthesis protein FliP compare
Pf6N2E2_5425 +0.5 0.9 hypothetical protein compare
Pf6N2E2_896 +0.5 2.1 Regulatory protein, LysR:LysR, substrate-binding compare
Pf6N2E2_1516 +0.5 1.6 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_3828 +0.5 1.4 tRNA (cytidine(34)-2'-O)-methyltransferase (EC 2.1.1.207) compare
Pf6N2E2_4504 +0.5 3.0 Alkanesulfonate monooxygenase (EC 1.14.14.5) compare
Pf6N2E2_4974 +0.5 3.4 DedA protein compare
Pf6N2E2_2279 +0.5 1.5 FIG00954981: hypothetical protein compare
Pf6N2E2_5057 +0.5 1.7 hypothetical protein compare
Pf6N2E2_4478 +0.5 2.9 FIG019278: hypothetical protein compare
Pf6N2E2_763 +0.4 1.9 Sigma-54 dependent transcriptional regulator compare
Pf6N2E2_5150 +0.4 2.4 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3903 +0.4 2.4 Ribosomal protein S6 glutaminyl transferase compare
Pf6N2E2_5207 +0.4 1.0 hypothetical protein compare
Pf6N2E2_4928 +0.4 0.9 Permeases of the major facilitator superfamily compare
Pf6N2E2_4766 +0.4 3.7 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf6N2E2_4615 +0.4 1.3 type IV pili signal transduction protein PilI compare
Pf6N2E2_1435 +0.4 1.3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase compare
Pf6N2E2_1865 +0.4 2.2 Beta-carotene hydroxylase compare
Pf6N2E2_1706 +0.4 1.1 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_3095 +0.4 0.8 hypothetical protein compare
Pf6N2E2_2739 +0.4 1.9 UPF0339 protein NMA1193/NMA1859 compare
Pf6N2E2_1424 +0.4 1.1 transcriptional regulator, TetR family compare
Pf6N2E2_3348 +0.4 2.2 hypothetical protein compare
Pf6N2E2_5723 +0.4 3.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_3003 +0.4 1.0 Bacteriophage protein GP46 compare
Pf6N2E2_3664 +0.4 3.1 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_1178 +0.4 2.1 3-oxoacyl-(acyl-carrier-protein) synthase compare
Pf6N2E2_3589 +0.4 0.9 Lysine decarboxylase family compare
Pf6N2E2_2593 +0.4 2.3 Flagellar M-ring protein FliF compare
Pf6N2E2_3772 +0.4 3.3 Polyhydroxyalkanoic acid synthase compare
Pf6N2E2_5763 +0.4 2.1 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
Pf6N2E2_3466 +0.4 1.2 FIG000605: protein co-occurring with transport systems (COG1739) compare
Pf6N2E2_2934 +0.4 1.3 lipoprotein, putative compare
Pf6N2E2_1984 +0.4 1.9 probable exported protein STY4558 compare
Pf6N2E2_841 +0.4 1.5 hypothetical protein compare
Pf6N2E2_734 +0.4 1.6 Molybdenum cofactor biosynthesis protein MoaA compare
Pf6N2E2_5497 +0.4 3.0 hypothetical protein compare
Pf6N2E2_829 +0.4 1.6 TesB-like acyl-CoA thioesterase 1 compare
Pf6N2E2_1081 +0.4 0.8 probable membrane protein YPO3302 compare
Pf6N2E2_6062 +0.4 2.6 2-methylcitrate synthase (EC 2.3.3.5) (from data) compare
Pf6N2E2_503 +0.4 2.3 sensor histidine kinase compare
Pf6N2E2_5758 +0.4 1.0 FIG00957314: hypothetical protein compare
Pf6N2E2_4731 +0.4 2.0 FIG00955037: hypothetical protein compare
Pf6N2E2_6087 +0.4 1.2 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_2281 +0.4 1.0 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_1504 +0.4 1.2 putative 2-pyrone-4,6-dicarboxylic acid hydrolase compare
Pf6N2E2_889 +0.4 2.2 Hydrolases of the alpha/beta superfamily compare
Pf6N2E2_136 +0.4 1.2 Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE compare
Pf6N2E2_1994 +0.4 1.7 putative lipoprotein compare
Pf6N2E2_193 +0.4 1.2 hypothetical protein compare
Pf6N2E2_2582 +0.4 1.7 Flagellar motor switch protein FliN compare
Pf6N2E2_349 +0.4 1.4 hypothetical protein compare
Pf6N2E2_5312 +0.4 1.0 FIG00964214: hypothetical protein compare
Pf6N2E2_4584 +0.4 1.8 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_4045 +0.4 1.4 FIG00953248: hypothetical protein compare
Pf6N2E2_4567 +0.4 1.5 ThiJ/PfpI family protein compare
Pf6N2E2_4535 +0.4 2.3 Type III secretion inner membrane protein (YscQ,homologous to flagellar export components) compare
Pf6N2E2_1249 +0.4 1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_4996 +0.4 1.7 LSU m3Psi1915 methyltransferase RlmH compare
Pf6N2E2_2646 +0.4 0.7 FIG00953416: hypothetical protein compare
Pf6N2E2_3982 +0.4 1.1 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf6N2E2_2867 +0.4 2.4 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium D-Lactate in Pseudomonas fluorescens FW300-N2E2

For carbon source Sodium D-Lactate across organisms