Experiment set2IT007 for Pseudomonas fluorescens FW300-N2E2

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a-Ketoglutaric acid disodium salt hydrate carbon source

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3630 -6.9 -4.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3842 -6.8 -4.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3839 -6.3 -4.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_64 -6.1 -4.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4826 -6.1 -8.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4825 -6.0 -9.2 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3253 -5.9 -5.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_77 -5.9 -5.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5487 -5.8 -5.8 Nitrogen regulation protein NR(I) conserved
Pf6N2E2_4596 -5.8 -10.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5175 -5.8 -15.3 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3751 -5.7 -13.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3782 -5.7 -5.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_71 -5.6 -7.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3783 -5.6 -6.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3610 -5.6 -6.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4597 -5.6 -10.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5176 -5.3 -10.7 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4047 -5.1 -7.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3752 -5.0 -24.8 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5014 -4.9 -2.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5488 -4.8 -17.2 C4-dicarboxylate transport sensor protein conserved
Pf6N2E2_4048 -4.4 -7.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_5177 -4.4 -11.3 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4564 -4.2 -8.6 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2074 -4.2 -2.8 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5486 -4.2 -15.5 Alpha-ketoglutarate permease (from data) conserved
Pf6N2E2_3932 -4.2 -5.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3251 -4.1 -13.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2073 -4.0 -9.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3940 -3.8 -11.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5156 -3.8 -3.6 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_3252 -3.8 -8.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_66 -3.7 -8.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3841 -3.5 -5.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5728 -3.3 -7.2 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5527 -3.3 -4.5 Cold shock protein CspC compare
Pf6N2E2_5579 -3.3 -9.2 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_50 -3.3 -9.5 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3762 -3.2 -8.5 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_302 -3.1 -6.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5006 -3.0 -10.2 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4638 -2.9 -5.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_63 -2.8 -4.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4759 -2.8 -15.5 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3170 -2.7 -6.9 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2465 -2.7 -6.3 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2217 -2.4 -7.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3248 -2.4 -7.5 Probable transmembrane protein compare
Pf6N2E2_4797 -2.3 -2.5 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4206 -2.3 -2.3 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_3763 -2.3 -2.6 hypothetical protein compare
Pf6N2E2_3460 -2.2 -2.7 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2574 -2.2 -3.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_4372 -2.2 -7.0 FIG00460773: hypothetical protein compare
Pf6N2E2_3984 -2.2 -9.1 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2277 -2.1 -2.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5667 -2.0 -8.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_5666 -2.0 -8.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_51 -1.9 -7.0 hypothetical protein compare
Pf6N2E2_4764 -1.8 -7.3 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_248 -1.8 -9.9 hypothetical protein compare
Pf6N2E2_4009 -1.8 -9.0 GGDEF domain protein compare
Pf6N2E2_4762 -1.8 -4.5 Biotin synthesis protein BioH compare
Pf6N2E2_5676 -1.7 -4.1 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5258 -1.7 -8.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4761 -1.7 -9.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_3346 -1.6 -6.5 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_2258 -1.6 -9.5 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5243 -1.6 -2.6 hypothetical protein compare
Pf6N2E2_4418 -1.6 -1.2 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_3899 -1.5 -8.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_2753 -1.5 -4.2 HtrA protease/chaperone protein compare
Pf6N2E2_5553 -1.5 -6.7 Quinolinate synthetase (EC 2.5.1.72) compare
Pf6N2E2_3349 -1.4 -2.6 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_2487 -1.4 -1.7 FIG00956090: hypothetical protein compare
Pf6N2E2_3938 -1.4 -10.4 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3875 -1.4 -1.5 FIG00953324: hypothetical protein compare
Pf6N2E2_5331 -1.4 -5.3 ATPase, AFG1 family compare
Pf6N2E2_5111 -1.4 -3.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_4631 -1.4 -6.8 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_4071 -1.3 -4.2 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2586 -1.3 -2.4 Hpt domain protein compare
Pf6N2E2_4417 -1.3 -4.5 Protein of unknown function DUF484 compare
Pf6N2E2_4763 -1.3 -6.4 Biotin synthesis protein BioC compare
Pf6N2E2_5219 -1.3 -7.7 FIG140336: TPR domain protein compare
Pf6N2E2_2473 -1.2 -1.6 Major outer membrane lipoprotein I compare
Pf6N2E2_4187 -1.2 -3.4 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_309 -1.2 -1.9 FIG00957702: hypothetical protein compare
Pf6N2E2_4077 -1.2 -1.6 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_5257 -1.2 -7.2 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5950 -1.2 -4.5 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2984 -1.2 -2.9 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_3835 -1.2 -4.2 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf6N2E2_156 -1.2 -2.4 Carbon storage regulator compare
Pf6N2E2_4615 -1.2 -2.1 type IV pili signal transduction protein PilI compare
Pf6N2E2_4579 -1.2 -2.0 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2413 -1.2 -2.3 FIG074102: hypothetical protein compare
Pf6N2E2_451 -1.1 -1.9 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_3534 -1.1 -2.6 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_2218 -1.1 -2.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2514 -1.1 -3.3 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_1932 -1.1 -3.9 Transcriptional regulator, IclR family compare
Pf6N2E2_2340 -1.0 -4.3 Transcriptional regulator, GntR family compare
Pf6N2E2_4527 -1.0 -2.9 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf6N2E2_3661 -1.0 -4.3 hypothetical protein compare
Pf6N2E2_4205 -1.0 -2.9 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_3062 -1.0 -4.0 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2061 -1.0 -3.8 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
Pf6N2E2_5584 -1.0 -2.8 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_5252 -1.0 -2.2 FIG00956396: hypothetical protein compare
Pf6N2E2_4743 -0.9 -1.2 hypothetical protein compare
Pf6N2E2_2693 -0.9 -1.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_70 -0.9 -3.4 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2919 -0.9 -2.2 FIG00955830: hypothetical protein compare
Pf6N2E2_1876 -0.9 -2.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_5723 -0.9 -6.4 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_89 -0.9 -1.6 hypothetical protein compare
Pf6N2E2_5665 -0.9 -4.3 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_1339 -0.9 -2.3 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_2756 -0.9 -4.7 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_4537 -0.9 -2.5 Type III secretion inner membrane protein (YscS,homologous to flagellar export components) compare
Pf6N2E2_5745 -0.9 -4.7 Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) compare
Pf6N2E2_2286 -0.9 -2.1 FIG00953287: hypothetical protein compare
Pf6N2E2_3514 -0.9 -2.9 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_4092 -0.9 -1.7 FIG00954395: hypothetical protein compare
Pf6N2E2_4162 -0.8 -1.9 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_5406 -0.8 -2.4 FIG00958224: hypothetical protein compare
Pf6N2E2_2681 -0.8 -2.7 3-phosphoglycerate kinase compare
Pf6N2E2_2264 -0.8 -2.5 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_2068 -0.8 -5.0 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_2518 -0.8 -2.9 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_4039 -0.8 -3.7 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_5508 -0.8 -1.9 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3942 -0.8 -5.2 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_178 -0.8 -1.0 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5077 -0.8 -3.0 hypothetical protein compare
Pf6N2E2_1723 -0.8 -1.6 Transcriptional regulator, TetR family compare
Pf6N2E2_4059 -0.8 -1.1 DNA-binding protein HU-alpha compare
Pf6N2E2_4448 -0.8 -1.6 probable P23 protein compare
Pf6N2E2_3039 -0.8 -3.8 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf6N2E2_1667 -0.8 -1.2 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_1315 -0.8 -1.2 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) compare
Pf6N2E2_663 -0.8 -2.4 Transcriptional activator of acetoin dehydrogenase operon AcoR compare
Pf6N2E2_4040 -0.8 -6.1 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) compare
Pf6N2E2_84 -0.8 -1.4 hypothetical protein compare
Pf6N2E2_3060 -0.8 -1.6 Outer membrane protein H precursor compare
Pf6N2E2_2886 -0.8 -6.4 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4454 -0.8 -3.6 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_2674 -0.8 -1.1 FIG00953856: hypothetical protein compare
Pf6N2E2_2758 -0.8 -5.7 L-aspartate oxidase (EC 1.4.3.16) compare
Pf6N2E2_48 -0.7 -2.5 FIG00955661: hypothetical protein compare
Pf6N2E2_3461 -0.7 -1.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_1705 -0.7 -1.3 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_342 -0.7 -1.2 DNA-binding response regulator compare
Pf6N2E2_3725 -0.7 -2.1 FIG085779: Lipoprotein compare
Pf6N2E2_3840 -0.7 -1.7 FIG00956267: hypothetical protein compare
Pf6N2E2_4038 -0.7 -5.0 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_2527 -0.7 -3.2 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_2852 -0.7 -5.0 GGDEF domain/EAL domain protein compare
Pf6N2E2_5520 -0.7 -3.3 Sensory box histidine kinase compare
Pf6N2E2_2402 -0.7 -1.9 hypothetical protein compare
Pf6N2E2_5955 -0.7 -2.4 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_3826 -0.7 -2.6 Nitrogen regulation protein NR(I) compare
Pf6N2E2_4352 -0.7 -1.7 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3300 -0.7 -2.1 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_959 -0.7 -2.5 putative membrane protein compare
Pf6N2E2_5536 -0.7 -1.0 Holliday junction DNA helicase RuvA compare
Pf6N2E2_160 -0.7 -1.4 hypothetical protein compare
Pf6N2E2_1400 -0.7 -4.6 Sensory box histidine kinase/response regulator compare
Pf6N2E2_4969 -0.7 -1.0 hypothetical protein compare
Pf6N2E2_1545 -0.7 -2.6 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_1626 -0.7 -3.5 Putative ATP-binding component of a transport system compare
Pf6N2E2_5001 -0.7 -1.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_1875 -0.7 -1.5 Protoporphyrinogen oxidase (EC 1.3.3.4) compare
Pf6N2E2_2167 -0.7 -4.3 hypothetical protein compare
Pf6N2E2_1717 -0.7 -4.2 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
Pf6N2E2_5986 -0.7 -1.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_724 -0.7 -1.6 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_3221 -0.7 -1.8 FIG00352444: hypothetical protein compare
Pf6N2E2_4273 -0.7 -4.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_1141 -0.6 -1.9 Lipid-A-disaccharide synthase (EC 2.4.1.182) compare
Pf6N2E2_922 -0.6 -1.8 FIG00794167: hypothetical protein compare
Pf6N2E2_3761 -0.6 -5.7 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf6N2E2_2636 -0.6 -2.0 FIG027190: Putative transmembrane protein compare
Pf6N2E2_2059 -0.6 -1.7 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf6N2E2_5741 -0.6 -3.0 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) compare
Pf6N2E2_2973 -0.6 -2.5 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1140 -0.6 -2.3 Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-) compare
Pf6N2E2_442 -0.6 -2.2 FIG00962345: hypothetical protein compare
Pf6N2E2_4747 -0.6 -1.3 Transmembrane sensor compare
Pf6N2E2_3589 -0.6 -1.8 Lysine decarboxylase family compare
Pf6N2E2_4543 -0.6 -2.3 hypothetical protein compare
Pf6N2E2_494 -0.6 -2.2 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) compare
Pf6N2E2_1316 -0.6 -1.9 P-hydroxyphenylacetate hydroxylase C1:reductase component compare
Pf6N2E2_640 -0.6 -2.4 Outer membrane TonB-dependent transducer VreA of trans-envelope signaling system compare
Pf6N2E2_4160 -0.6 -1.1 Cytochrome c5 compare
Pf6N2E2_2490 -0.6 -2.4 sensor histidine kinase compare
Pf6N2E2_4710 -0.6 -1.3 hypothetical protein compare
Pf6N2E2_5300 -0.6 -4.7 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source a-Ketoglutaric acid disodium salt hydrate in Pseudomonas fluorescens FW300-N2E2

For carbon source a-Ketoglutaric acid disodium salt hydrate across organisms