Experiment set2IT005 for Pseudomonas fluorescens FW300-N2E3

Compare to:

LB with Cisplatin 0.006 mg/ml

200 most important genes:

  gene name fitness t score description  
AO353_04055 -4.4 -2.7 methionine--tRNA ligase compare
AO353_07850 -3.5 -2.4 ATP-dependent RNA helicase compare
AO353_09745 -3.2 -2.1 hypothetical protein compare
AO353_27090 -3.1 -2.4 hypothetical protein compare
AO353_05625 -3.0 -2.0 transcription elongation factor GreA compare
AO353_14220 -3.0 -2.0 ribosomal large subunit pseudouridine synthase D compare
AO353_20510 -3.0 -2.7 amidase compare
AO353_07105 -2.9 -1.0 biotin--protein ligase compare
AO353_27665 -2.8 -3.9 arginyl-tRNA-protein transferase compare
AO353_24405 -2.8 -4.0 ArsR family transcriptional regulator compare
AO353_02085 -2.8 -2.7 methylthioribose-1-phosphate isomerase compare
AO353_20545 -2.8 -6.1 excinuclease ABC subunit B conserved
AO353_24750 -2.7 -5.9 DNA damage response nuclease (from data) conserved
AO353_08470 -2.7 -1.9 RNA pyrophosphohydrolase compare
AO353_16810 -2.7 -1.8 recombinase RecX compare
AO353_13980 -2.6 -3.6 DNA repair protein RadA compare
AO353_19530 -2.6 -1.2 quinohemoprotein amine dehydrogenase compare
AO353_02515 -2.6 -4.6 recombination-associated protein RdgC compare
AO353_06855 -2.6 -10.1 ABC-ATPase UvrA conserved
AO353_11850 -2.6 -4.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
AO353_11340 -2.6 -1.7 MarR family transcriptional regulator compare
AO353_16375 -2.5 -2.3 hypothetical protein compare
AO353_21830 -2.5 -13.4 chemotaxis protein CheY compare
AO353_00435 -2.5 -10.7 transcription-repair coupling factor conserved
AO353_15385 -2.5 -1.4 hypothetical protein compare
AO353_09150 -2.5 -3.5 cytochrome C2 compare
AO353_04810 -2.4 -1.4 hypothetical protein compare
AO353_09345 -2.4 -2.7 hypothetical protein compare
AO353_04365 -2.4 -2.3 recombinase XerD compare
AO353_14585 -2.4 -2.3 ribosomal-protein-alanine acetyltransferase compare
AO353_16495 -2.3 -3.1 zinc metallopeptidase RseP compare
AO353_27675 -2.3 -6.2 ATP-dependent Clp protease ATP-binding subunit ClpA compare
AO353_05660 -2.3 -4.6 DNA repair protein RecN conserved
AO353_02250 -2.3 -2.6 chorismate synthase compare
AO353_17885 -2.3 -1.1 hypothetical protein compare
AO353_02440 -2.3 -9.0 peptidase S41 compare
AO353_17020 -2.2 -6.0 ATP-dependent DNA helicase DinG conserved
AO353_02390 -2.2 -8.5 aminopeptidase conserved
AO353_11915 -2.2 -4.8 agmatine deiminase compare
AO353_06850 -2.2 -2.1 MFS transporter compare
AO353_09050 -2.2 -1.5 recombinase XerC compare
AO353_07610 -2.2 -1.0 hypothetical protein compare
AO353_18430 -2.2 -7.8 ATP-dependent DNA helicase RecQ conserved
AO353_21625 -2.2 -2.3 Fe/S biogenesis protein NfuA compare
AO353_20185 -2.1 -5.5 DNA-binding protein compare
AO353_13160 -2.1 -1.4 membrane protease HflC compare
AO353_09720 -2.1 -1.8 hypothetical protein compare
AO353_00495 -2.1 -1.9 DNA topoisomerase I compare
AO353_04190 -2.1 -1.4 glycerol-3-phosphate dehydrogenase compare
AO353_09860 -2.1 -8.7 histidine kinase compare
AO353_03590 -2.1 -2.3 crossover junction endodeoxyribonuclease RuvC compare
AO353_08350 -2.1 -5.0 hypothetical protein compare
AO353_10480 -2.1 -4.5 recombinase RecF conserved
AO353_09890 -2.0 -2.0 phosphate ABC transporter ATP-binding protein compare
AO353_09320 -2.0 -5.6 ATP-dependent DNA helicase RecG compare
AO353_20590 -2.0 -1.4 hydrolase compare
AO353_12105 -2.0 -4.4 peptidase S41 compare
AO353_27180 -2.0 -3.5 peptidase M48, Ste24p compare
AO353_01405 -2.0 -5.9 23S rRNA pseudouridylate synthase compare
AO353_18425 -2.0 -3.4 hypothetical protein compare
AO353_21835 -2.0 -3.8 excinuclease ABC subunit C compare
AO353_00675 -2.0 -4.1 recombination protein RecR compare
AO353_20800 -2.0 -0.9 hypothetical protein compare
AO353_04185 -2.0 -5.1 DeoR family transcriptional regulator compare
AO353_10950 -1.9 -5.8 thiol:disulfide interchange protein compare
AO353_04320 -1.9 -3.7 single-stranded-DNA-specific exonuclease RecJ compare
AO353_11750 -1.9 -1.8 ATPase compare
AO353_27650 -1.9 -3.2 cell division protein FtsK compare
AO353_08170 -1.9 -4.3 hypothetical protein compare
AO353_14775 -1.9 -4.5 hypothetical protein compare
AO353_23710 -1.9 -4.6 protein BatD compare
AO353_26550 -1.9 -1.5 hypothetical protein compare
AO353_02780 -1.9 -9.0 tRNA 2-thiocytidine biosynthesis protein TtcA conserved
AO353_16915 -1.9 -7.0 hypothetical protein compare
AO353_10930 -1.9 -4.4 DNA polymerase I compare
AO353_21770 -1.9 -2.5 3-hydroxybutyrate dehydrogenase compare
AO353_14935 -1.9 -3.2 aminopeptidase compare
AO353_23715 -1.9 -5.0 hypothetical protein compare
AO353_27685 -1.9 -4.0 cold-shock protein compare
AO353_17625 -1.8 -6.9 RNA polymerase subunit sigma compare
AO353_10055 -1.8 -7.9 DNA helicase II compare
AO353_16430 -1.8 -6.8 cysteine sulfinate desulfinase compare
AO353_06455 -1.8 -1.7 D-alanyl-D-alanine carboxypeptidase compare
AO353_01410 -1.8 -1.7 ribonuclease E compare
AO353_11050 -1.8 -3.6 hypothetical protein compare
AO353_01915 -1.8 -2.3 GlcG protein compare
AO353_21440 -1.8 -3.3 hypothetical protein compare
AO353_14150 -1.8 -1.6 peptidylprolyl isomerase compare
AO353_08910 -1.8 -2.0 hypothetical protein compare
AO353_16425 -1.8 -1.6 Fe-S metabolism protein SufE compare
AO353_18540 -1.8 -1.2 pseudouridine synthase compare
AO353_27415 -1.8 -2.5 hypothetical protein compare
AO353_27720 -1.8 -3.4 cupin compare
AO353_23720 -1.8 -3.2 BatB protein compare
AO353_24340 -1.8 -1.7 TetR family transcriptional regulator compare
AO353_09905 -1.8 -6.9 phosphate-binding protein compare
AO353_04500 -1.8 -1.2 DNA repair protein RecO compare
AO353_24190 -1.7 -3.1 hypothetical protein compare
AO353_19250 -1.7 -1.6 molybdenum cofactor guanylyltransferase compare
AO353_12690 -1.7 -0.8 acyl carrier protein compare
AO353_07155 -1.7 -6.0 N-acetyl-gamma-glutamyl-phosphate reductase compare
AO353_08265 -1.7 -3.5 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
AO353_05125 -1.7 -3.5 BolA family transcriptional regulator compare
AO353_11730 -1.7 -5.3 glutamate--cysteine ligase compare
AO353_03715 -1.7 -1.9 H-NS histone compare
AO353_09900 -1.7 -7.9 phosphate ABC transporter permease compare
AO353_19060 -1.7 -2.7 CysB family transcriptional regulator compare
AO353_06540 -1.7 -1.8 hypothetical protein compare
AO353_09915 -1.7 -5.3 long-chain acyl-CoA thioester hydrolase compare
AO353_15825 -1.7 -2.8 serine acetyltransferase compare
AO353_18780 -1.7 -4.9 cobyrinic acid a,c-diamide synthase compare
AO353_19750 -1.7 -2.2 diaminopimelate epimerase compare
AO353_25015 -1.7 -3.3 polyketide cyclase compare
AO353_01595 -1.7 -2.4 Flp pilus assembly protein CpaB compare
AO353_21410 -1.6 -1.7 hypothetical protein compare
AO353_02710 -1.6 -9.0 (p)ppGpp synthetase compare
AO353_04355 -1.6 -1.1 homoserine dehydrogenase compare
AO353_04090 -1.6 -2.0 leucyl-tRNA synthetase compare
AO353_15905 -1.6 -5.0 outer membrane protein assembly factor BamB compare
AO353_29000 -1.6 -2.7 pyridoxal-5'-phosphate-dependent protein subunit beta compare
AO353_05130 -1.6 -1.6 anti-anti-sigma factor compare
AO353_20860 -1.6 -1.6 hypothetical protein compare
AO353_05550 -1.6 -4.7 pseudouridine synthase compare
AO353_08620 -1.6 -1.5 hypothetical protein compare
AO353_08885 -1.6 -9.6 polyphosphate kinase compare
AO353_05205 -1.6 -8.9 peptidase PmbA conserved
AO353_02175 -1.6 -2.7 carbon storage regulator compare
AO353_28700 -1.5 -2.4 hypothetical protein compare
AO353_16805 -1.5 -2.5 recombinase RecA compare
AO353_20175 -1.5 -2.3 ATP-dependent Clp protease proteolytic subunit compare
AO353_16745 -1.5 -1.7 ArsR family transcriptional regulator compare
AO353_20910 -1.5 -4.0 MerR family transcriptional regulator compare
AO353_18775 -1.5 -5.2 flagellar biosynthesis protein FlhF compare
AO353_13050 -1.5 -3.3 DNA topoisomerase IV compare
AO353_20270 -1.5 -3.4 spore coat protein compare
AO353_03580 -1.5 -1.0 ATP-dependent DNA helicase RuvB compare
AO353_06040 -1.5 -1.0 exodeoxyribonuclease V subunit alpha compare
AO353_20680 -1.5 -2.6 cell division protein compare
AO353_01355 -1.5 -4.6 3-oxoacyl-ACP synthase compare
AO353_25845 -1.5 -2.5 GNAT family acetyltransferase compare
AO353_03830 -1.5 -1.6 antibiotic biosynthesis monooxygenase compare
AO353_04565 -1.5 -2.7 nucleoid-associated protein compare
AO353_23725 -1.5 -2.9 hypothetical protein compare
AO353_19235 -1.5 -4.6 DNA damage response gene with a putative DNA binding domain (PA0922-like) (from data) conserved
AO353_15290 -1.4 -6.5 methyltransferase compare
AO353_25035 -1.4 -3.7 integrase compare
AO353_27695 -1.4 -5.1 isocitrate dehydrogenase compare
AO353_15270 -1.4 -2.1 phospholipid-binding protein compare
AO353_03100 -1.4 -1.3 XRE family transcriptional regulator compare
AO353_14420 -1.4 -1.9 molecular chaperone DnaK compare
AO353_24755 -1.4 -5.9 ATP-dependent DNA helicase conserved
AO353_23730 -1.4 -1.9 hypothetical protein compare
AO353_29350 -1.4 -7.9 DNA polymerase II conserved
AO353_17410 -1.4 -1.9 arylsulfate sulfotransferase compare
AO353_26520 -1.4 -2.3 TetR family transcriptional regulator compare
AO353_09240 -1.4 -1.8 acetylglutamate kinase compare
AO353_07725 -1.4 -6.6 hypothetical protein compare
AO353_24255 -1.4 -2.7 hypothetical protein compare
AO353_22735 -1.4 -2.3 hypothetical protein compare
AO353_06780 -1.4 -8.9 DNA repair helicase Lhr (from data) conserved
AO353_01615 -1.4 -2.4 pilus assembly protein PilA compare
AO353_00510 -1.4 -3.5 multifunctional fatty acid oxidation complex subunit alpha compare
AO353_00725 -1.4 -4.0 GntR family transcriptional regulator compare
AO353_26870 -1.3 -2.7 AP endonuclease compare
AO353_06045 -1.3 -3.1 exodeoxyribonuclease V subunit beta compare
AO353_13720 -1.3 -8.4 arginine decarboxylase compare
AO353_06710 -1.3 -1.6 riboflavin synthase subunit alpha compare
AO353_26835 -1.3 -2.7 transcriptional regulator compare
AO353_27215 -1.3 -1.8 hypothetical protein compare
AO353_26115 -1.3 -1.2 hypothetical protein compare
AO353_11740 -1.3 -6.2 DNA damage response protein (yhgF like) (from data) conserved
AO353_17340 -1.3 -3.4 glycerol acyltransferase compare
AO353_24745 -1.3 -1.9 hypothetical protein compare
AO353_26320 -1.3 -3.5 hypothetical protein compare
AO353_17735 -1.3 -3.7 hypothetical protein compare
AO353_05215 -1.3 -6.8 protease TldD conserved
AO353_26945 -1.3 -1.6 transcriptional regulator compare
AO353_08110 -1.3 -3.7 glutathione synthetase compare
AO353_09315 -1.3 -5.0 LysR family transcriptional regulator compare
AO353_21615 -1.3 -6.3 methionine synthase compare
AO353_14915 -1.3 -2.2 (2Fe-2S)-binding protein compare
AO353_28110 -1.3 -3.5 TetR family transcriptional regulator compare
AO353_23450 -1.3 -2.2 LysR family transcriptional regulator compare
AO353_14370 -1.3 -4.5 glucose-6-phosphate isomerase compare
AO353_20480 -1.2 -3.5 hypothetical protein compare
AO353_24445 -1.2 -3.8 ethyl tert-butyl ether degradation protein EthD compare
AO353_03000 -1.2 -1.5 topoisomerase II compare
AO353_23385 -1.2 -4.0 trans-2-enoyl-CoA reductase compare
AO353_09495 -1.2 -3.7 hypothetical protein compare
AO353_24130 -1.2 -1.9 hypothetical protein compare
AO353_09265 -1.2 -1.5 hypothetical protein compare
AO353_26070 -1.2 -2.0 hypothetical protein compare
AO353_02465 -1.2 -1.3 hypothetical protein compare
AO353_09000 -1.2 -3.6 argininosuccinate lyase compare
AO353_14030 -1.2 -6.5 ABC transporter ATP-binding protein compare
AO353_01215 -1.2 -5.4 hypothetical protein compare
AO353_00515 -1.2 -2.1 hypothetical protein compare
AO353_12365 -1.2 -2.6 phosphoribosyl-AMP cyclohydrolase compare
AO353_27680 -1.2 -3.1 ATP-dependent Clp protease adaptor ClpS compare
AO353_07895 -1.2 -1.6 fructose-bisphosphate aldolase compare


Specific Phenotypes

For 29 genes in this experiment

For stress Cisplatin in Pseudomonas fluorescens FW300-N2E3

For stress Cisplatin across organisms