Experiment set2IT005 for Pedobacter sp. GW460-11-11-14-LB5

Compare to:

R2A with D-Cycloserine 0.2 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
CA265_RS14990 +7.5 64.8 amino acid transporter compare
CA265_RS17690 +4.5 30.9 DNA-binding response regulator compare
CA265_RS05725 +4.5 29.9 hypothetical protein compare
CA265_RS17695 +4.2 21.2 hypothetical protein compare
CA265_RS11605 +3.7 28.2 Proline dehydrogenase (EC 1.5.5.2) (from data) compare
CA265_RS25185 +3.5 8.1 glycine dehydrogenase (aminomethyl-transferring) compare
CA265_RS25215 +3.3 13.2 MBL fold hydrolase compare
CA265_RS18235 +3.2 12.9 peptidase compare
CA265_RS18080 +2.9 13.7 hypothetical protein compare
CA265_RS01035 +2.9 18.8 hypothetical protein compare
CA265_RS18760 +2.7 14.9 ribonuclease III compare
CA265_RS15880 +2.6 20.0 sugar ABC transporter ATP-binding protein compare
CA265_RS18755 +2.6 10.8 beta-ketoacyl-[acyl-carrier-protein] synthase II compare
CA265_RS08905 +2.3 11.0 DNA helicase RecQ compare
CA265_RS04940 +2.3 2.0 RecX family transcriptional regulator compare
CA265_RS09810 +2.2 15.6 glucose-6-phosphate dehydrogenase compare
CA265_RS24700 +2.2 3.2 hypothetical protein compare
CA265_RS25110 +2.2 14.7 polyprenyl synthetase compare
CA265_RS12740 +2.1 7.0 hypothetical protein compare
CA265_RS22630 +2.0 9.2 nucleoside-diphosphate sugar epimerase compare
CA265_RS06220 +2.0 9.5 NifU family protein compare
CA265_RS24255 +2.0 9.2 sugar kinase compare
CA265_RS18230 +2.0 5.4 two-component sensor histidine kinase compare
CA265_RS15805 +2.0 14.2 acetolactate synthase, large subunit, biosynthetic type compare
CA265_RS06200 +1.9 12.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB compare
CA265_RS04400 +1.9 13.7 hypothetical protein compare
CA265_RS10155 +1.9 12.3 serine acetyltransferase compare
CA265_RS04395 +1.9 14.3 heptosyltransferase compare
CA265_RS05730 +1.8 5.0 hypothetical protein compare
CA265_RS13195 +1.8 3.3 SAM-dependent methyltransferase compare
CA265_RS23960 +1.8 2.9 glycine cleavage system protein T compare
CA265_RS20070 +1.8 8.2 NadR compare
CA265_RS05720 +1.7 6.1 hypothetical protein compare
CA265_RS05655 +1.7 14.3 hypothetical protein compare
CA265_RS15810 +1.7 6.7 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) compare
CA265_RS15795 +1.7 10.6 dihydroxy-acid dehydratase compare
CA265_RS14910 +1.6 10.9 ABC transporter ATP-binding protein compare
CA265_RS14530 +1.6 2.6 nicotinate-nucleotide diphosphorylase (carboxylating) compare
CA265_RS06400 +1.6 11.3 DNA-binding response regulator compare
CA265_RS19590 +1.6 5.7 hypothetical protein compare
CA265_RS09805 +1.6 8.2 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
CA265_RS08105 +1.5 10.9 DUF983 domain-containing protein compare
CA265_RS09525 +1.5 10.1 protein-(glutamine-N5) methyltransferase, release factor-specific compare
CA265_RS10660 +1.5 6.5 acyl dehydratase compare
CA265_RS08855 +1.5 10.9 MFS transporter compare
CA265_RS15010 +1.5 7.3 hypothetical protein compare
CA265_RS07515 +1.5 10.9 pyridoxal phosphate-dependent aminotransferase compare
CA265_RS10150 +1.5 5.8 cysteine synthase B compare
CA265_RS05660 +1.5 11.9 DNA-binding response regulator compare
CA265_RS00650 +1.4 5.4 hypothetical protein compare
CA265_RS02960 +1.4 6.9 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
CA265_RS17595 +1.4 8.2 MarR family transcriptional regulator compare
CA265_RS23190 +1.4 4.4 transcription elongation factor GreA compare
CA265_RS20990 +1.3 3.6 sugar transporter compare
CA265_RS05010 +1.3 6.5 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) compare
CA265_RS09415 +1.3 1.3 hypothetical protein compare
CA265_RS19165 +1.3 3.4 serine hydroxymethyltransferase compare
CA265_RS18555 +1.2 3.1 hypothetical protein compare
CA265_RS21885 +1.2 4.9 6-pyruvoyl tetrahydrobiopterin synthase compare
CA265_RS19180 +1.2 10.1 gliding motility protein RemB compare
CA265_RS17775 +1.2 4.4 hypothetical protein compare
CA265_RS17190 +1.2 9.7 beta-N-acetylglucosaminidase compare
CA265_RS19195 +1.2 6.1 UDP-GlcNAc--UDP-phosphate GlcNAc-1-phosphate transferase compare
CA265_RS14535 +1.2 3.7 DUF4783 domain-containing protein compare
CA265_RS00785 +1.2 4.7 hypothetical protein compare
CA265_RS25450 +1.1 2.4 iron-sulfur cluster assembly accessory protein compare
CA265_RS19255 +1.1 5.3 ExsB family protein compare
CA265_RS16605 +1.1 8.9 1-pyrroline-5-carboxylate dehydrogenase compare
CA265_RS08785 +1.1 5.0 hypothetical protein compare
CA265_RS12600 +1.1 2.2 hypothetical protein compare
CA265_RS19275 +1.1 2.1 hypothetical protein compare
CA265_RS06610 +1.1 7.9 transmembrane HD family protein compare
CA265_RS15825 +1.0 4.2 ketol-acid reductoisomerase compare
CA265_RS00815 +1.0 3.7 hypothetical protein compare
CA265_RS21910 +1.0 7.5 glycoside hydrolase compare
CA265_RS03520 +1.0 6.7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
CA265_RS05070 +1.0 5.9 Na+/H+ antiporter NhaA compare
CA265_RS13175 +1.0 1.9 hypothetical protein compare
CA265_RS09400 +1.0 1.6 hypothetical protein compare
CA265_RS25270 +1.0 2.4 hypothetical protein compare
CA265_RS04100 +1.0 3.7 uroporphyrinogen-III C-methyltransferase compare
CA265_RS18435 +1.0 7.3 peptide chain release factor 3 compare
CA265_RS19220 +1.0 4.4 hypothetical protein compare
CA265_RS15800 +1.0 1.7 DNA-binding protein compare
CA265_RS15845 +1.0 5.3 molybdenum ABC transporter ATP-binding protein compare
CA265_RS21000 +0.9 4.0 ribosome silencing factor compare
CA265_RS02990 +0.9 5.4 mannosyltransferase compare
CA265_RS21185 +0.9 5.2 L-aspartate oxidase compare
CA265_RS02115 +0.9 5.5 Fur family transcriptional regulator compare
CA265_RS23565 +0.9 2.0 NADH dehydrogenase compare
CA265_RS05160 +0.9 8.3 hypothetical protein compare
CA265_RS14625 +0.9 7.2 hypothetical protein compare
CA265_RS05985 +0.9 1.7 hypothetical protein compare
CA265_RS19385 +0.9 6.5 glycosyl transferase compare
CA265_RS09570 +0.9 4.6 RNA methyltransferase compare
CA265_RS10595 +0.9 4.6 dicarboxylate/amino acid:cation symporter compare
CA265_RS14765 +0.9 7.3 alkaline phosphatase family protein compare
CA265_RS13145 +0.9 3.4 hypothetical protein compare
CA265_RS08775 +0.9 1.3 hypothetical protein compare
CA265_RS14170 +0.9 4.0 DNA repair protein compare
CA265_RS04295 +0.8 1.2 transcriptional regulator compare
CA265_RS13235 +0.8 4.6 hypothetical protein compare
CA265_RS24780 +0.8 4.3 nucleoside-diphosphate kinase compare
CA265_RS03565 +0.8 4.1 phosphonate ABC transporter ATP-binding protein compare
CA265_RS22635 +0.8 2.3 phosphoserine phosphatase (EC 3.1.3.3) (from data) compare
CA265_RS15785 +0.8 3.0 branched-chain-amino-acid transaminase compare
CA265_RS14125 +0.8 2.2 hypothetical protein compare
CA265_RS04260 +0.8 5.7 trigger factor compare
CA265_RS23120 +0.8 3.8 hypothetical protein compare
CA265_RS11620 +0.8 6.1 sterol desaturase compare
CA265_RS06175 +0.8 1.7 hypothetical protein compare
CA265_RS19250 +0.8 4.9 hypothetical protein compare
CA265_RS19605 +0.8 5.0 serine hydrolase compare
CA265_RS21900 +0.8 6.4 two-component sensor histidine kinase compare
CA265_RS19290 +0.8 3.4 N-acetyltransferase compare
CA265_RS19995 +0.8 4.1 AI-2E family transporter compare
CA265_RS13265 +0.8 2.4 DNA-binding protein compare
CA265_RS14655 +0.8 2.7 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase compare
CA265_RS07455 +0.8 2.3 hypothetical protein compare
CA265_RS16390 +0.8 4.7 polysaccharide deacetylase family protein compare
CA265_RS18020 +0.8 4.6 hypothetical protein compare
CA265_RS13500 +0.7 3.0 hypothetical protein compare
CA265_RS18315 +0.7 5.6 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase compare
CA265_RS04095 +0.7 4.1 nitrite reductase compare
CA265_RS19285 +0.7 4.5 oxidoreductase compare
CA265_RS06510 +0.7 3.6 hypothetical protein compare
CA265_RS08875 +0.7 2.6 tetratricopeptide repeat protein compare
CA265_RS12725 +0.7 4.9 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
CA265_RS17680 +0.7 4.9 hypothetical protein compare
CA265_RS09840 +0.7 2.7 YajQ family cyclic di-GMP-binding protein compare
CA265_RS16820 +0.7 2.6 type I methionyl aminopeptidase compare
CA265_RS04105 +0.7 4.9 siroheme synthase compare
CA265_RS15145 +0.7 4.7 amino acid permease compare
CA265_RS16040 +0.7 5.0 hypothetical protein compare
CA265_RS07840 +0.7 3.5 hypothetical protein compare
CA265_RS00465 +0.7 2.0 cupin compare
CA265_RS09405 +0.7 2.7 hypothetical protein compare
CA265_RS22825 +0.7 2.4 reactive intermediate/imine deaminase compare
CA265_RS03900 +0.7 3.2 hypothetical protein compare
CA265_RS18015 +0.7 4.5 glycosyl transferase compare
CA265_RS15105 +0.7 2.2 glutamyl-tRNA amidotransferase compare
CA265_RS08220 +0.7 4.6 DNA mismatch repair protein MutS compare
CA265_RS10415 +0.7 4.6 type I methionyl aminopeptidase compare
CA265_RS09560 +0.7 5.1 galactose-1-epimerase compare
CA265_RS13285 +0.7 4.5 magnesium transporter compare
CA265_RS23195 +0.6 4.2 HIT family protein compare
CA265_RS00940 +0.6 2.1 hypothetical protein compare
CA265_RS05750 +0.6 5.5 amino acid transporter compare
CA265_RS19320 +0.6 1.9 histidinol phosphatase compare
CA265_RS13985 +0.6 2.2 hypothetical protein compare
CA265_RS22775 +0.6 4.3 glycosyl hydrolase compare
CA265_RS00395 +0.6 1.3 hypothetical protein compare
CA265_RS22785 +0.6 3.6 hypothetical protein compare
CA265_RS22895 +0.6 2.7 aminodeoxychorismate/anthranilate synthase component II compare
CA265_RS14055 +0.6 3.7 acyl-CoA thioesterase compare
CA265_RS04265 +0.6 3.1 hypothetical protein compare
CA265_RS08900 +0.6 1.6 D-arabinose 5-phosphate isomerase compare
CA265_RS24895 +0.6 3.4 hypothetical protein compare
CA265_RS15170 +0.6 4.8 peptidase M23 compare
CA265_RS05260 +0.6 1.6 hypothetical protein compare
CA265_RS06275 +0.6 4.6 aspartate kinase compare
CA265_RS24770 +0.6 1.6 hypothetical protein compare
CA265_RS21905 +0.6 3.8 hypothetical protein compare
CA265_RS05705 +0.6 3.0 aldehyde dehydrogenase (NADP(+)) compare
CA265_RS24945 +0.6 2.8 hypothetical protein compare
CA265_RS17205 +0.6 2.9 rhomboid family intramembrane serine protease compare
CA265_RS04120 +0.6 4.2 sulfate adenylyltransferase compare
CA265_RS16295 +0.6 3.6 LacI family transcriptional regulator compare
CA265_RS19980 +0.6 3.3 hypothetical protein compare
CA265_RS20195 +0.6 1.6 hypothetical protein compare
CA265_RS24055 +0.6 2.4 GNAT family N-acetyltransferase compare
CA265_RS13025 +0.6 4.5 transmembrane glycosyltransferase compare
CA265_RS01650 +0.6 4.5 hypothetical protein compare
CA265_RS08295 +0.6 2.5 hypothetical protein compare
CA265_RS10135 +0.6 3.8 hypothetical protein compare
CA265_RS10235 +0.6 1.4 hypothetical protein compare
CA265_RS09500 +0.6 3.4 hypothetical protein compare
CA265_RS20270 +0.6 2.3 methionine--tRNA ligase compare
CA265_RS12860 +0.6 3.1 nitroreductase compare
CA265_RS20705 +0.6 1.2 conjugal transfer protein compare
CA265_RS08765 +0.6 2.8 response regulator compare
CA265_RS11670 +0.6 3.4 hypothetical protein compare
CA265_RS17330 +0.6 1.5 hypothetical protein compare
CA265_RS19295 +0.6 3.3 transcriptional regulator compare
CA265_RS05165 +0.6 3.5 hypothetical protein compare
CA265_RS20665 +0.6 2.3 hypothetical protein compare
CA265_RS14065 +0.6 3.6 hypothetical protein compare
CA265_RS06395 +0.6 3.8 hypothetical protein compare
CA265_RS25355 +0.6 3.0 DUF2807 domain-containing protein compare
CA265_RS08385 +0.6 3.0 sodium:solute symporter compare
CA265_RS20805 +0.6 2.6 methyltransferase compare
CA265_RS00420 +0.6 1.2 FUSC family protein compare
CA265_RS19575 +0.6 1.5 glycoside hydrolase compare
CA265_RS08780 +0.6 3.8 hypothetical protein compare
CA265_RS01660 +0.6 3.5 hypothetical protein compare
CA265_RS04390 +0.6 1.6 histidine phosphatase family protein compare
CA265_RS06270 +0.6 4.1 hypothetical protein compare
CA265_RS04340 +0.6 2.7 hypothetical protein compare
CA265_RS01635 +0.6 4.2 hypothetical protein compare
CA265_RS23180 +0.6 2.4 peroxiredoxin compare


Specific Phenotypes

For 6 genes in this experiment

For stress D-Cycloserine in Pedobacter sp. GW460-11-11-14-LB5

For stress D-Cycloserine across organisms