Experiment set2IT005 for Shewanella loihica PV-4

Compare to:

Sodium pyruvate carbon source

200 most detrimental genes:

  gene name fitness t score description  
Shew_0383 +5.4 26.6 malate dehydrogenase (RefSeq) compare
Shew_0866 +5.0 9.8 arginine repressor (RefSeq) compare
Shew_1058 +3.8 18.9 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_0618 +3.5 5.5 hypothetical protein (RefSeq) compare
Shew_1325 +3.4 17.0 acetyltransferase-like protein (RefSeq) compare
Shew_3440 +3.3 4.5 prepilin peptidase (RefSeq) compare
Shew_1319 +3.3 24.8 DegT/DnrJ/EryC1/StrS aminotransferase (RefSeq) compare
Shew_1383 fliA +3.2 16.3 flagellar biosynthesis sigma factor (RefSeq) compare
Shew_1769 +3.2 5.6 NapD family protein (RefSeq) compare
Shew_1329 +3.2 22.6 N-acylneuraminate-9-phosphate synthase (RefSeq) compare
Shew_2768 +3.2 10.4 flagellar motor protein PomA (RefSeq) compare
Shew_1327 +3.2 16.6 hypothetical protein (RefSeq) compare
Shew_1521 +3.1 10.7 OmpA/MotB domain-containing protein (RefSeq) compare
Shew_1328 +3.1 12.2 acylneuraminate cytidylyltransferase (RefSeq) compare
Shew_1369 fliI +3.0 19.5 flagellum-specific ATP synthase (RefSeq) compare
Shew_1334 +3.0 9.1 3-oxoacyl-(acyl-carrier-protein) synthase (RefSeq) compare
Shew_2767 motB +2.9 9.2 flagellar motor protein MotB (RefSeq) compare
Shew_1926 +2.9 8.3 transketolase, central region (RefSeq) compare
Shew_1370 +2.9 4.7 flagellar export protein FliJ (RefSeq) compare
Shew_1322 +2.9 16.0 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_3622 hslO +2.9 19.3 Hsp33-like chaperonin (RefSeq) compare
Shew_1332 +2.9 21.4 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_2329 +2.9 11.1 putative two-component response-regulatory protein YehT (RefSeq) conserved
Shew_1318 +2.8 18.7 polysaccharide biosynthesis protein CapD (RefSeq) compare
Shew_1333 +2.8 13.8 3-oxoacyl-(acyl-carrier-protein) synthase (RefSeq) compare
Shew_1324 +2.8 14.7 hypothetical protein (RefSeq) compare
Shew_1352 flgI +2.7 15.4 flagellar basal body P-ring protein (RefSeq) compare
Shew_1371 +2.7 14.5 flagellar hook-length control protein (RefSeq) compare
Shew_1809 +2.7 18.3 NAD-glutamate dehydrogenase (RefSeq) compare
Shew_1349 flgF +2.7 14.9 flagellar basal body rod protein FlgF (RefSeq) compare
Shew_1372 fliL +2.7 6.8 flagellar basal body-associated protein FliL (RefSeq) compare
Shew_1331 +2.6 15.7 spore coat polysaccharide biosynthesis protein glycosyltransferase-like (RefSeq) compare
Shew_1350 flgG +2.6 10.9 flagellar basal body rod protein FlgG (RefSeq) compare
Shew_1365 +2.6 6.2 flagellar hook-basal body complex subunit FliE (RefSeq) compare
Shew_1379 flhB +2.6 8.7 flagellar biosynthesis protein FlhB (RefSeq) compare
Shew_1347 flgD +2.6 8.0 flagellar basal body rod modification protein (RefSeq) compare
Shew_1323 +2.6 6.3 acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II-like protein (RefSeq) compare
Shew_2328 +2.6 10.4 signal transduction histidine kinase, LytS (RefSeq) conserved
Shew_1366 fliF +2.6 12.8 flagellar MS-ring protein (RefSeq) compare
Shew_1354 +2.5 7.3 flagellar hook-associated protein FlgK (RefSeq) compare
Shew_1819 +2.5 6.7 GntR family transcriptional regulator (RefSeq) compare
Shew_3689 +2.5 10.5 hypothetical protein (RefSeq) compare
Shew_1376 fliP +2.5 14.2 flagellar biosynthesis protein FliP (RefSeq) compare
Shew_0920 +2.5 11.7 major facilitator transporter (RefSeq) conserved
Shew_2330 +2.5 14.1 carbon starvation protein CstA (RefSeq) conserved
Shew_1361 fliS +2.5 17.1 flagellar protein FliS (RefSeq) compare
Shew_3708 +2.4 15.1 TetR family transcriptional regulator (RefSeq) compare
Shew_1326 +2.4 13.2 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_2572 +2.4 10.1 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1353 flgJ +2.4 6.5 peptidoglycan hydrolase (RefSeq) compare
Shew_1362 +2.4 9.5 sigma-54 dependent trancsriptional regulator (RefSeq) compare
Shew_1925 +2.4 12.0 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_1380 flhA +2.4 12.0 flagellar biosynthesis protein FlhA (RefSeq) compare
Shew_1357 +2.4 17.0 flagellin domain-containing protein (RefSeq) compare
Shew_0225 +2.4 2.2 phosphoheptose isomerase (RefSeq) compare
Shew_2906 +2.3 3.0 hypothetical protein (RefSeq) compare
Shew_1355 flgL +2.3 10.5 flagellar hook-associated protein FlgL (RefSeq) compare
Shew_2498 +2.3 2.5 extracellular solute-binding protein (RefSeq) compare
Shew_2892 +2.3 8.8 major facilitator transporter (RefSeq) compare
Shew_1348 flgE +2.3 6.3 flagellar hook protein FlgE (RefSeq) compare
Shew_2502 +2.2 6.7 ABC transporter-related protein (RefSeq) compare
Shew_1367 fliG +2.2 8.2 flagellar motor switch protein G (RefSeq) compare
Shew_1375 +2.2 9.8 flagellar biosynthesis protein, FliO (RefSeq) compare
Shew_1533 +2.2 15.8 acetyl-CoA synthetase (RefSeq) compare
Shew_1340 +2.1 11.2 FlgN family protein (RefSeq) compare
Shew_2026 +2.1 6.2 alanine dehydrogenase (RefSeq) compare
Shew_2907 +2.1 4.2 invasion gene expression up-regulator, SirB (RefSeq) compare
Shew_1317 +2.1 17.7 TPR repeat-containing protein (RefSeq) compare
Shew_1368 +2.1 5.4 flagellar assembly protein FliH (RefSeq) compare
Shew_1374 fliN +2.0 5.6 flagellar motor switch protein (RefSeq) compare
Shew_2770 +2.0 1.8 polyprenyl synthetase (RefSeq) compare
Shew_0470 +2.0 2.7 MATE efflux family protein (RefSeq) compare
Shew_1927 +2.0 2.6 dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_0995 +2.0 3.8 phage integrase family protein (RefSeq) compare
Shew_1438 +2.0 8.0 fumarylacetoacetate (FAA) hydrolase (RefSeq) compare
Shew_1439 +1.9 12.0 maleylacetoacetate isomerase (RefSeq) compare
Shew_1359 +1.8 5.3 flagellar hook-associated 2 domain-containing protein (RefSeq) compare
Shew_1363 +1.8 13.7 PAS/PAC sensor signal transduction histidine kinase (RefSeq) compare
Shew_0220 +1.8 7.8 phosphoglycolate phosphatase (RefSeq) compare
Shew_3696 +1.8 10.1 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (RefSeq) compare
Shew_3473 +1.7 13.6 response regulator receiver protein (RefSeq) compare
Shew_2141 +1.7 6.9 lytic murein transglycosylase (RefSeq) compare
Shew_3055 +1.7 3.9 CMP/dCMP deaminase, zinc-binding (RefSeq) compare
Shew_0409 +1.7 10.4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (RefSeq) compare
Shew_3290 +1.7 3.2 Sel1 domain-containing protein (RefSeq) compare
Shew_1437 +1.7 8.7 transcriptional regulator, TyrR (RefSeq) compare
Shew_2349 +1.6 7.9 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_3065 +1.6 7.2 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_0127 +1.6 5.2 LexA repressor (RefSeq) compare
Shew_1210 +1.6 4.9 stationary-phase survival protein SurE (RefSeq) compare
Shew_3657 +1.6 13.2 oligopeptidase A (RefSeq) compare
Shew_3759 +1.6 10.8 imidazolonepropionase (RefSeq) compare
Shew_1470 +1.5 7.9 sulfatase (RefSeq) compare
Shew_2025 +1.5 3.9 leucine-responsive transcriptional regulator (RefSeq) compare
Shew_3709 +1.5 10.4 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_2061 +1.4 2.2 radical SAM domain-containing protein (RefSeq) compare
Shew_3695 +1.4 2.3 cytidyltransferase-like protein (RefSeq) compare
Shew_0438 +1.4 1.3 GumN family protein (RefSeq) compare
Shew_0852 +1.4 4.7 hypothetical protein (RefSeq) compare
Shew_1373 fliM +1.4 3.9 flagellar motor switch protein FliM (RefSeq) compare
Shew_1657 sucC +1.4 1.9 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_0339 +1.3 6.9 ATP-dependent RNA helicase RhlB (RefSeq) compare
Shew_3063 +1.3 2.1 glycine cleavage system protein H (RefSeq) compare
Shew_1364 +1.3 8.2 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1555 +1.3 2.6 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_3427 +1.3 6.8 patatin (RefSeq) compare
Shew_1776 +1.2 4.0 acetolactate synthase 3 catalytic subunit (RefSeq) compare
Shew_1714 +1.2 2.5 alpha/beta hydrolase fold (RefSeq) compare
Shew_1183 +1.2 6.4 putative ABC transporter ATP-binding protein (RefSeq) compare
Shew_3710 tdh +1.2 9.0 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_1404 +1.2 9.1 dTDP-4-dehydrorhamnose 3,5-epimerase (RefSeq) compare
Shew_1625 +1.2 3.2 L-serine dehydratase 1 (RefSeq) compare
Shew_1978 +1.2 1.2 hypothetical protein (RefSeq) compare
Shew_1330 +1.2 2.7 Rieske (2Fe-2S) domain-containing protein (RefSeq) compare
Shew_0722 +1.2 1.3 hypothetical protein (RefSeq) compare
Shew_0795 +1.2 1.8 hypothetical protein (RefSeq) compare
Shew_1407 +1.2 9.5 short-chain dehydrogenase/reductase SDR (RefSeq) compare
Shew_1288 +1.2 2.8 type IV pilus biogenesis/stability protein PilW (RefSeq) compare
Shew_1004 +1.2 3.7 undecaprenyl pyrophosphate phosphatase (RefSeq) compare
Shew_1713 +1.2 1.7 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_1289 +1.1 2.5 hypothetical protein (RefSeq) compare
Shew_0695 +1.1 1.7 hypothetical protein (RefSeq) compare
Shew_2140 +1.1 2.1 hypothetical protein (RefSeq) compare
Shew_1679 +1.1 1.1 TetR family transcriptional regulator (RefSeq) compare
Shew_1531 grxA +1.1 2.4 glutaredoxin 1 (RefSeq) compare
Shew_0408 +1.1 5.7 hypothetical protein (RefSeq) compare
Shew_2282 +1.1 1.8 Fis family transcriptional regulator (RefSeq) compare
Shew_1059 +1.1 2.3 hypothetical protein (RefSeq) compare
Shew_1337 +1.1 6.3 hypothetical protein (RefSeq) compare
Shew_1607 +1.1 2.0 thioesterase superfamily protein (RefSeq) compare
Shew_1092 +1.1 5.7 amino acid carrier protein (RefSeq) compare
Shew_0620 +1.1 1.7 ion transport 2 domain-containing protein (RefSeq) compare
Shew_2795 +1.1 4.7 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_2890 +1.0 1.5 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_2110 +1.0 6.2 hypothetical protein (RefSeq) compare
Shew_3442 +1.0 1.9 hypothetical protein (RefSeq) compare
Shew_1011 +1.0 4.5 citrate transporter (RefSeq) compare
Shew_2573 +1.0 4.5 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_3072 +1.0 2.4 cold-shock protein, DNA-binding (RefSeq) compare
Shew_3653 +1.0 1.3 hypothetical protein (RefSeq) compare
Shew_1951 +1.0 2.4 aromatic amino acid aminotransferase (RefSeq) compare
Shew_1411 +1.0 6.5 hexapaptide repeat-containing transferase (RefSeq) compare
Shew_0973 +1.0 3.8 extracellular solute-binding protein (RefSeq) compare
Shew_3301 +1.0 2.3 toluene tolerance family protein (RefSeq) compare
Shew_0821 +1.0 1.6 mitomycin resistance protein (RefSeq) compare
Shew_3064 gcvT +1.0 6.4 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_1920 +1.0 3.5 alpha/beta hydrolase fold (RefSeq) compare
Shew_1841 +1.0 1.4 peptidase M48, Ste24p (RefSeq) compare
Shew_2905 +1.0 3.6 hypothetical protein (RefSeq) compare
Shew_1781 +1.0 1.5 hypothetical protein (RefSeq) compare
Shew_3192 +0.9 2.1 hypothetical protein (RefSeq) compare
Shew_3742 +0.9 4.4 flagellar basal body-associated protein FliL-like protein (RefSeq) compare
Shew_2357 +0.9 1.3 D,D-heptose 1,7-bisphosphate phosphatase (RefSeq) compare
Shew_3483 dut +0.9 0.8 deoxyuridine 5'-triphosphate nucleotidohydrolase (RefSeq) compare
Shew_1961 +0.9 2.5 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_1341 +0.9 2.4 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_1586 +0.9 2.7 diacylglycerol kinase (RefSeq) compare
Shew_1995 +0.9 1.4 PP-loop domain-containing protein (RefSeq) compare
Shew_0659 +0.9 2.7 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) compare
Shew_2436 +0.9 4.3 membrane protein involved in aromatic hydrocarbon degradation (RefSeq) compare
Shew_3647 +0.9 3.8 hypothetical protein (RefSeq) compare
Shew_1391 +0.9 1.4 CheW protein (RefSeq) compare
Shew_3292 +0.9 0.9 hypothetical protein (RefSeq) compare
Shew_2372 +0.9 1.4 small component of L-lactate and L-malate uptake system (from data) compare
Shew_0594 +0.9 2.4 hypothetical protein (RefSeq) compare
Shew_2403 +0.9 1.2 arylesterase (RefSeq) compare
Shew_0777 +0.9 1.5 two-component response regulator (RefSeq) compare
Shew_1076 +0.9 2.6 Trp operon repressor (RefSeq) compare
Shew_1386 +0.9 3.5 CheA signal transduction histidine kinase (RefSeq) compare
Shew_3697 +0.8 3.9 glycosyl transferase family protein (RefSeq) compare
Shew_3394 +0.8 0.8 MscS mechanosensitive ion channel (RefSeq) compare
Shew_1673 fabG +0.8 1.0 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) compare
Shew_0261 +0.8 0.6 hypothetical protein (RefSeq) compare
Shew_2708 +0.8 2.2 Na(+)-translocating NADH-quinone reductase subunit B (RefSeq) compare
Shew_2646 +0.8 0.7 hypothetical protein (RefSeq) compare
Shew_0448 +0.8 1.9 periplasmic solute binding protein (RefSeq) compare
Shew_1023 +0.8 2.6 hypothetical protein (RefSeq) compare
Shew_2188 +0.8 3.6 long-chain-fatty-acid--CoA ligase (RefSeq) compare
Shew_2589 +0.8 1.5 hypothetical protein (RefSeq) compare
Shew_2458 +0.8 0.8 glutathione S-transferase domain-containing protein (RefSeq) compare
Shew_1994 +0.8 1.6 universal stress protein UspE (RefSeq) compare
Shew_1281 +0.8 1.7 hypothetical protein (RefSeq) compare
Shew_2900 +0.8 3.4 hypothetical protein (RefSeq) compare
Shew_3271 +0.8 4.1 galactokinase (RefSeq) compare
Shew_3805 +0.8 3.0 rhodanese domain-containing protein (RefSeq) compare
Shew_1932 cls +0.8 3.1 cardiolipin synthetase (RefSeq) compare
Shew_3617 +0.8 1.2 general secretion pathway protein F (RefSeq) compare
Shew_3488 +0.8 2.5 ribonuclease PH (RefSeq) compare
Shew_2406 +0.8 1.4 AraC family transcriptional regulator (RefSeq) compare
Shew_2039 +0.8 4.8 GCN5-related N-acetyltransferase (RefSeq) compare
Shew_1981 +0.8 2.1 AraC family transcriptional regulator (RefSeq) compare
Shew_2453 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_1397 +0.7 2.1 amino acid/peptide transporter (RefSeq) compare
Shew_0851 +0.7 4.9 phospho-2-dehydro-3-deoxyheptonate aldolase (RefSeq) compare
Shew_0340 +0.7 3.7 Ppx/GppA phosphatase (RefSeq) compare
Shew_0450 +0.7 3.0 1-acyl-sn-glycerol-3-phosphate acyltransferase (RefSeq) compare
Shew_2480 +0.7 3.9 TonB-dependent receptor (RefSeq) compare
Shew_2558 +0.7 2.8 1,4-dihydroxy-2-naphthoate octaprenyltransferase (RefSeq) compare
Shew_3619 +0.7 3.6 general secretion pathway protein D (RefSeq) compare
Shew_1223 +0.7 0.7 hypothetical protein (RefSeq) compare


Specific Phenotypes

For 10 genes in this experiment

For carbon source Sodium pyruvate in Shewanella loihica PV-4

For carbon source Sodium pyruvate across organisms