Experiment set2H48 for Pseudomonas stutzeri RCH2

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
Psest_3931 -4.6 -3.2 Signal transduction histidine kinase, nitrogen specific compare
Psest_0279 -4.5 -6.1 methionine biosynthesis protein MetW compare
Psest_2584 -4.1 -7.8 Phosphoribosylanthranilate isomerase compare
Psest_0155 -4.0 -7.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3647 -3.8 -6.9 Indole-3-glycerol phosphate synthase compare
Psest_0153 -3.7 -11.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2590 -3.6 -1.6 3-isopropylmalate dehydratase, small subunit compare
Psest_3298 -3.6 -12.0 histidinol dehydrogenase compare
Psest_0062 -3.5 -8.8 tryptophan synthase, alpha subunit compare
Psest_3650 -3.5 -10.5 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3299 -3.5 -13.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_2579 -3.3 -8.3 amidophosphoribosyltransferase compare
Psest_3338 -3.3 -2.0 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_3649 -3.3 -7.7 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_2591 -3.3 -3.7 3-isopropylmalate dehydratase, large subunit compare
Psest_3648 -3.2 -6.7 anthranilate phosphoribosyltransferase compare
Psest_0489 -3.2 -3.1 phosphoserine phosphatase SerB compare
Psest_0508 -3.1 -8.3 gamma-glutamyl phosphate reductase compare
Psest_0063 -3.1 -3.7 tryptophan synthase, beta subunit compare
Psest_0097 -3.1 -1.7 phosphonates metabolism transcriptional regulator PhnF compare
Psest_0325 -3.0 -13.9 Putative threonine efflux protein compare
Psest_3862 -2.9 -14.6 phosphoenolpyruvate-protein phosphotransferase compare
Psest_1082 -2.9 -2.0 Enoyl-CoA hydratase/carnithine racemase compare
Psest_1474 -2.9 -5.8 phosphoribosylaminoimidazole synthetase compare
Psest_0152 -2.9 -7.0 Imidazoleglycerol-phosphate dehydratase compare
Psest_0687 -2.8 -9.3 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0450 -2.8 -9.2 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) conserved
Psest_1496 -2.8 -2.1 Holliday junction DNA helicase, RuvA subunit compare
Psest_2845 -2.8 -9.2 [Protein-PII] uridylyltransferase compare
Psest_1951 -2.8 -2.6 Uncharacterized protein conserved in bacteria compare
Psest_1013 -2.8 -3.3 phosphoribosylamine--glycine ligase compare
Psest_4298 -2.8 -0.9 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_2757 -2.7 -1.2 hypothetical protein compare
Psest_0326 -2.6 -11.4 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_3449 -2.5 -1.3 DJ-1 family protein compare
Psest_2714 -2.5 -2.4 7-cyano-7-deazaguanine reductase compare
Psest_0999 -2.5 -4.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1602 -2.5 -2.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3995 -2.4 -2.5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3185 -2.4 -2.0 MoxR-like ATPases compare
Psest_3943 -2.4 -1.6 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0313 -2.3 -4.2 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_2589 -2.3 -8.0 3-isopropylmalate dehydrogenase compare
Psest_1473 -2.3 -5.5 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0280 -2.3 -9.1 homoserine O-acetyltransferase compare
Psest_3864 -2.2 -9.2 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_3518 -2.2 -1.4 Transcriptional regulators compare
Psest_0297 -2.2 -4.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1452 -2.2 -8.9 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_1070 -2.2 -3.5 Predicted membrane protein compare
Psest_0094 -2.2 -1.9 Uncharacterized enzyme of phosphonate metabolism compare
Psest_0103 -2.1 -2.4 triphosphoribosyl-dephospho-CoA synthase MdcB compare
Psest_0920 -2.1 -6.8 Transcriptional regulators conserved
Psest_3777 -2.1 -2.8 diguanylate cyclase (GGDEF) domain compare
Psest_3317 -2.1 -3.2 Phosphotransferase System HPr (HPr) Family compare
Psest_3766 -2.0 -2.3 Uncharacterized protein conserved in bacteria compare
Psest_2120 -2.0 -1.9 Transcriptional regulator compare
Psest_3013 -2.0 -1.9 cobyrinic acid a,c-diamide synthase compare
Psest_1295 -1.9 -6.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3159 -1.9 -5.7 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0644 -1.9 -3.1 siderophore ferric iron reductase, AHA_1954 family compare
Psest_3932 -1.9 -4.1 nitrogen regulation protein NR(I) compare
Psest_0292 -1.8 -3.2 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_3123 -1.8 -3.7 dihydroorotase, homodimeric type compare
Psest_2578 -1.8 -7.7 O-succinylhomoserine sulfhydrylase compare
Psest_2766 -1.8 -1.1 hypothetical protein compare
Psest_0114 -1.8 -1.5 RNA polymerase sigma factor, sigma-70 family compare
Psest_1814 -1.8 -13.2 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_2401 -1.8 -4.0 Uncharacterized conserved protein compare
Psest_2419 -1.8 -4.9 AraC-type DNA-binding domain-containing proteins compare
Psest_0327 -1.8 -7.4 Transcriptional regulator compare
Psest_3384 -1.8 -7.5 glutamate 5-kinase compare
Psest_4242 -1.8 -4.1 type VI secretion system FHA domain protein compare
Psest_2357 -1.8 -2.0 Short-chain dehydrogenases of various substrate specificities compare
Psest_1870 -1.8 -1.6 Transcriptional regulators compare
Psest_1506 -1.8 -5.3 queuosine biosynthesis protein QueC compare
Psest_2360 -1.8 -1.7 Uncharacterized protein, putative amidase compare
Psest_3896 -1.7 -1.5 arsenite-activated ATPase ArsA compare
Psest_4301 -1.7 -4.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1424 -1.7 -1.2 Lipoate-protein ligase A compare
Psest_3936 -1.7 -2.2 ATP-dependent protease HslVU, peptidase subunit compare
Psest_1180 -1.7 -4.0 hydroxypyruvate isomerase compare
Psest_4297 -1.7 -7.9 PAS domain S-box compare
Psest_0568 -1.6 -2.3 pseudouridine synthase compare
Psest_3086 -1.6 -5.4 hypothetical protein compare
Psest_4001 -1.6 -3.9 acetylornithine deacetylase (ArgE) compare
Psest_3008 -1.6 -2.2 cobyric acid synthase CobQ compare
Psest_3322 -1.6 -11.5 TIGR02099 family protein compare
Psest_0998 -1.6 -3.0 poly(A) polymerase compare
Psest_1381 -1.6 -4.4 Predicted alpha/beta hydrolase compare
Psest_2414 -1.6 -2.8 TolR protein compare
Psest_3998 -1.6 -3.1 glutamate--cysteine ligase compare
Psest_2405 -1.6 -2.0 NAD-dependent protein deacetylases, SIR2 family compare
Psest_3810 -1.6 -2.6 orotate phosphoribosyltransferase compare
Psest_3565 -1.6 -1.2 hypothetical protein compare
Psest_3178 -1.6 -2.8 formyltetrahydrofolate deformylase compare
Psest_0054 -1.6 -2.9 hypothetical protein compare
Psest_2448 -1.5 -2.5 AraC-type DNA-binding domain-containing proteins compare
Psest_1576 -1.5 -5.3 Periplasmic glucans biosynthesis protein compare
Psest_3573 -1.5 -2.8 dTDP-4-dehydrorhamnose reductase compare
Psest_3323 -1.5 -3.0 ribonuclease, Rne/Rng family compare
Psest_4108 -1.5 -2.7 seryl-tRNA(sec) selenium transferase compare
Psest_0285 -1.5 -5.9 pilus retraction protein PilT compare
Psest_1813 -1.5 -8.0 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_3937 -1.5 -0.7 ATP-dependent protease HslVU, ATPase subunit compare
Psest_1406 -1.4 -2.6 His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_4053 -1.4 -4.5 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_1397 -1.4 -2.2 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_3944 -1.4 -1.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_2119 -1.4 -2.2 Glycine/D-amino acid oxidases (deaminating) compare
Psest_1907 -1.4 -1.0 hypothetical protein compare
Psest_2756 -1.4 -1.2 hypothetical protein compare
Psest_1888 -1.4 -1.0 Sua5/YciO/YrdC/YwlC family protein compare
Psest_1881 -1.4 -3.0 Nitroreductase compare
Psest_1562 -1.4 -1.5 Uncharacterized protein conserved in bacteria compare
Psest_0537 -1.4 -1.6 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_3546 -1.4 -0.6 Phosphatidylglycerophosphatase A and related proteins compare
Psest_1704 -1.3 -0.9 Dehydrogenases (flavoproteins) compare
Psest_1215 -1.3 -1.7 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) compare
Psest_3878 -1.3 -2.2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2158 -1.3 -8.5 alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase compare
Psest_1359 -1.3 -3.4 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_3321 -1.3 -5.1 Predicted amidohydrolase compare
Psest_3085 -1.3 -5.8 methyltransferase, putative compare
Psest_2809 -1.3 -2.0 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_2764 -1.3 -1.1 hypothetical protein compare
Psest_1911 -1.3 -4.7 spermidine synthase compare
Psest_2726 -1.3 -1.1 Rhodanese-related sulfurtransferase compare
Psest_3304 -1.3 -5.1 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_2397 -1.2 -4.0 Deoxyribodipyrimidine photolyase compare
Psest_2407 -1.2 -2.1 nitrite reductase [NAD(P)H], small subunit compare
Psest_0209 -1.2 -0.9 membrane protein AbrB duplication compare
Psest_3447 -1.2 -0.5 Uncharacterized MobA-related protein compare
Psest_2384 -1.2 -1.9 Uncharacterized protein conserved in bacteria compare
Psest_4396 -1.2 -5.9 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_2398 -1.2 -2.9 SnoaL-like polyketide cyclase. compare
Psest_0872 -1.2 -1.2 Helix-turn-helix. compare
Psest_3161 -1.2 -6.0 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family conserved
Psest_4005 -1.2 -3.6 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Psest_4363 -1.2 -5.6 ATPases involved in chromosome partitioning compare
Psest_2890 -1.2 -5.4 diguanylate cyclase (GGDEF) domain compare
Psest_1451 -1.2 -1.6 Uncharacterized ABC-type transport system, permease components compare
Psest_4133 -1.2 -4.4 RNA polymerase sigma factor, sigma-70 family compare
Psest_0395 -1.2 -4.2 His Kinase A (phosphoacceptor) domain./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_4057 -1.2 -3.2 Peroxiredoxin compare
Psest_0392 -1.2 -6.5 Signal transduction histidine kinase compare
Psest_3744 -1.2 -3.1 Disulfide bond formation protein DsbB compare
Psest_2390 -1.2 -4.5 hypothetical protein compare
Psest_1361 -1.2 -3.7 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_0060 -1.2 -1.4 Predicted Fe-S protein compare
Psest_3767 -1.2 -2.7 tyrosine recombinase XerC compare
Psest_3012 -1.2 -1.7 cob(II)yrinic acid a,c-diamide reductase compare
Psest_3473 -1.2 -2.5 hypothetical protein compare
Psest_3550 -1.2 -1.2 3,4-dihydroxy-2-butanone 4-phosphate synthase compare
Psest_1080 -1.2 -5.0 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_0805 -1.2 -2.4 hypothetical protein compare
Psest_2088 -1.2 -1.2 Uncharacterized protein conserved in bacteria compare
Psest_0318 -1.2 -4.4 NAD-dependent DNA ligase (contains BRCT domain type II) compare
Psest_0708 -1.2 -1.5 outer membrane assembly lipoprotein YfiO compare
Psest_0119 -1.2 -1.4 hypothetical protein compare
Psest_0281 -1.1 -4.6 Dynamin family. compare
Psest_3163 -1.1 -5.3 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_0045 -1.1 -3.5 hypothetical protein compare
Psest_3079 -1.1 -5.0 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) compare
Psest_0355 -1.1 -0.9 Glycine cleavage system regulatory protein compare
Psest_0532 -1.1 -3.6 tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB compare
Psest_1081 -1.1 -3.3 hypothetical protein compare
Psest_0678 -1.1 -2.3 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region compare
Psest_0445 -1.1 -6.6 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3476 -1.1 -0.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3186 -1.1 -3.6 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_3010 -1.1 -4.2 cobalamin biosynthesis protein CobD compare
Psest_2121 -1.1 -3.0 Predicted ATPase compare
Psest_0024 -1.1 -4.8 LysM domain. compare
Psest_1599 -1.1 -4.0 heavy metal sensor kinase compare
Psest_1077 -1.1 -3.7 acetyl-CoA:acetoacetate CoA transferase, B subunit (EC 2.8.3.8) (from data) compare
Psest_2387 -1.1 -6.6 FolB domain compare
Psest_1449 -1.1 -3.7 Short-chain dehydrogenases of various substrate specificities compare
Psest_2666 -1.1 -4.8 Predicted acyl-CoA transferases/carnitine dehydratase compare
Psest_3997 -1.1 -3.5 uncharacterized domain 1 compare
Psest_0652 -1.1 -1.8 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components compare
Psest_1567 -1.1 -1.7 Transcriptional regulator compare
Psest_0852 -1.1 -2.6 glucose-6-phosphate 1-dehydrogenase compare
Psest_2243 -1.1 -1.0 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_2027 -1.1 -5.9 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_0243 -1.1 -0.5 hypothetical protein compare
Psest_0501 -1.1 -1.5 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_3478 -1.1 -0.8 Cytochrome B561 compare
Psest_1052 -1.1 -2.6 Uncharacterized protein involved in chromosome partitioning compare
Psest_0207 -1.1 -1.5 hypothetical protein compare
Psest_4287 -1.1 -2.9 Predicted glutamine amidotransferases compare
Psest_0732 -1.1 -1.5 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_4303 -1.1 -0.6 HEAT repeat. compare
Psest_0402 -1.1 -1.8 glycosyltransferase, MGT family compare
Psest_0634 -1.1 -3.7 hypothetical protein compare
Psest_0691 -1.1 -6.4 ribonuclease R compare
Psest_0662 -1.1 -1.5 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1136 -1.0 -3.2 Prolyl oligopeptidase family. compare
Psest_0212 -1.0 -0.7 exodeoxyribonuclease V, gamma subunit compare
Psest_3996 -1.0 -4.7 Transcriptional accessory protein compare


Specific Phenotypes

For 22 genes in this experiment

For nitrogen source L-Isoleucine in Pseudomonas stutzeri RCH2

For nitrogen source L-Isoleucine across organisms