Experiment set2H23 for Pseudomonas stutzeri RCH2

Compare to:

L-Alanine nitrogen source

200 most important genes:

  gene name fitness t score description  
Psest_0279 -5.8 -5.6 methionine biosynthesis protein MetW compare
Psest_2578 -5.6 -13.0 O-succinylhomoserine sulfhydrylase compare
Psest_0508 -5.5 -8.4 gamma-glutamyl phosphate reductase compare
Psest_3862 -5.5 -16.5 phosphoenolpyruvate-protein phosphotransferase compare
Psest_3818 -5.4 -6.5 endoribonuclease L-PSP, putative compare
Psest_3647 -5.4 -6.4 Indole-3-glycerol phosphate synthase compare
Psest_2650 -5.4 -5.2 hypothetical protein compare
Psest_0153 -5.3 -13.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2088 -5.2 -3.2 Uncharacterized protein conserved in bacteria compare
Psest_0954 -5.2 -10.0 Fe-S oxidoreductase compare
Psest_2584 -5.2 -6.1 Phosphoribosylanthranilate isomerase compare
Psest_0952 -5.1 -3.5 Uncharacterized conserved protein compare
Psest_2988 -5.1 -9.7 aspartate kinase, monofunctional class compare
Psest_3384 -5.0 -9.6 glutamate 5-kinase compare
Psest_3648 -5.0 -7.6 anthranilate phosphoribosyltransferase compare
Psest_3649 -4.9 -7.5 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3794 -4.9 -10.8 Transcriptional regulators conserved
Psest_3650 -4.8 -11.3 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_2579 -4.8 -8.0 amidophosphoribosyltransferase compare
Psest_2591 -4.7 -5.6 3-isopropylmalate dehydratase, large subunit compare
Psest_3864 -4.7 -15.7 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0155 -4.7 -6.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0152 -4.7 -7.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_2945 -4.7 -3.2 septum site-determining protein MinC compare
Psest_0411 -4.7 -11.2 biotin synthetase compare
Psest_0325 -4.6 -17.3 Putative threonine efflux protein compare
Psest_3298 -4.6 -12.6 histidinol dehydrogenase compare
Psest_0280 -4.6 -17.9 homoserine O-acetyltransferase compare
Psest_3317 -4.5 -8.6 Phosphotransferase System HPr (HPr) Family compare
Psest_3793 -4.5 -7.5 D-alanine dehydrogenase (EC 1.4.99.-) (from data) conserved
Psest_0062 -4.4 -9.0 tryptophan synthase, alpha subunit compare
Psest_3710 -4.4 -13.6 glutamate synthase small subunit family protein, proteobacterial compare
Psest_2589 -4.4 -14.7 3-isopropylmalate dehydrogenase compare
Psest_2329 -4.3 -20.0 Transcriptional regulator compare
Psest_3932 -4.2 -5.0 nitrogen regulation protein NR(I) compare
Psest_0687 -4.2 -10.2 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3299 -4.2 -15.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_1452 -4.2 -9.8 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_0953 -4.1 -14.4 iron-sulfur cluster-binding protein compare
Psest_3711 -4.0 -13.0 Glutamate synthase domain 2 compare
Psest_1474 -4.0 -7.1 phosphoribosylaminoimidazole synthetase compare
Psest_3866 -3.9 -19.7 threonine ammonia-lyase, biosynthetic, long form compare
Psest_1640 -3.9 -17.1 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_4084 -3.9 -19.7 oxaloacetate decarboxylase alpha subunit compare
Psest_3297 -3.9 -14.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_1496 -3.8 -3.4 Holliday junction DNA helicase, RuvA subunit compare
Psest_0313 -3.7 -3.6 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3944 -3.7 -3.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0489 -3.7 -4.4 phosphoserine phosphatase SerB compare
Psest_3338 -3.7 -3.5 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1295 -3.7 -10.5 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3159 -3.6 -12.4 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0063 -3.6 -7.2 tryptophan synthase, beta subunit compare
Psest_3226 -3.6 -1.9 Predicted membrane protein compare
Psest_3931 -3.5 -5.7 Signal transduction histidine kinase, nitrogen specific compare
Psest_0218 -3.4 -3.2 Acyl-CoA hydrolase compare
Psest_1037 -3.3 -4.1 acetolactate synthase, small subunit compare
Psest_0414 -3.3 -6.9 biotin biosynthesis protein BioC compare
Psest_3123 -3.3 -6.1 dihydroorotase, homodimeric type compare
Psest_1013 -3.2 -5.2 phosphoribosylamine--glycine ligase compare
Psest_4085 -3.2 -17.4 Biotin carboxylase compare
Psest_3810 -3.1 -3.7 orotate phosphoribosyltransferase compare
Psest_2714 -3.1 -3.0 7-cyano-7-deazaguanine reductase compare
Psest_2090 -3.1 -3.1 Protein of unknown function (DUF2970). compare
Psest_0306 -3.1 -17.9 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_3792 -3.0 -4.3 Putative translation initiation inhibitor, yjgF family compare
Psest_3943 -3.0 -2.9 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0412 -3.0 -13.3 8-amino-7-oxononanoate synthase compare
Psest_0998 -3.0 -4.8 poly(A) polymerase compare
Psest_4086 -2.9 -12.9 Transcriptional regulator compare
Psest_1947 -2.9 -3.4 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_0691 -2.8 -15.2 ribonuclease R compare
Psest_3092 -2.8 -2.8 ribonuclease III, bacterial compare
Psest_0284 -2.7 -16.0 pyridoxal phosphate enzyme, YggS family compare
Psest_2104 -2.7 -3.6 IscR-regulated protein YhgI compare
Psest_2946 -2.7 -7.0 septum site-determining protein MinD compare
Psest_2590 -2.7 -2.2 3-isopropylmalate dehydratase, small subunit compare
Psest_0398 -2.6 -7.5 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain compare
Psest_0413 -2.5 -8.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_0969 -2.5 -3.7 transcription elongation factor GreA compare
Psest_0722 -2.4 -11.2 Predicted ATPase compare
Psest_0415 -2.4 -4.1 dethiobiotin synthase compare
Psest_1686 -2.4 -6.2 fatty acid/phospholipid synthesis protein PlsX compare
Psest_2864 -2.3 -7.0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0498 -2.3 -2.5 ribosome small subunit-dependent GTPase A compare
Psest_0951 -2.2 -11.4 FAD/FMN-containing dehydrogenases compare
Psest_3302 -2.2 -8.0 Predicted membrane protein compare
Psest_1492 -2.1 -10.5 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_2316 -2.1 -12.6 phosphoenolpyruvate synthase compare
Psest_0958 -2.0 -9.9 Oligoketide cyclase/lipid transport protein compare
Psest_3339 -1.9 -6.3 Signal transduction histidine kinase compare
Psest_0542 -1.9 -7.7 AMP nucleosidase compare
Psest_0260 -1.9 -1.7 Cell division protein compare
Psest_0326 -1.8 -4.9 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_2532 -1.8 -4.9 Uncharacterized protein conserved in bacteria compare
Psest_3721 -1.8 -8.2 Malic enzyme compare
Psest_2845 -1.8 -7.4 [Protein-PII] uridylyltransferase compare
Psest_1292 -1.7 -8.4 monothiol glutaredoxin, Grx4 family compare
Psest_4281 -1.7 -11.6 ABC-type spermidine/putrescine transport system, permease component I compare
Psest_1871 -1.7 -8.4 Predicted esterase of the alpha-beta hydrolase superfamily compare
Psest_1242 -1.7 -3.1 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_2719 -1.7 -5.6 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_3767 -1.7 -4.8 tyrosine recombinase XerC compare
Psest_3998 -1.6 -5.0 glutamate--cysteine ligase compare
Psest_2863 -1.6 -5.7 Transcriptional regulator compare
Psest_0103 -1.6 -2.7 triphosphoribosyl-dephospho-CoA synthase MdcB compare
Psest_3843 -1.6 -8.8 4-hydroxybenzoate synthetase (chorismate lyase) compare
Psest_3438 -1.6 -8.5 Glutamate dehydrogenase/leucine dehydrogenase compare
Psest_1870 -1.6 -2.4 Transcriptional regulators compare
Psest_1527 -1.6 -9.9 Na+/proline symporter compare
Psest_4282 -1.6 -8.6 spermidine/putrescine ABC transporter ATP-binding subunit compare
Psest_1313 -1.6 -2.0 Uncharacterized conserved small protein compare
Psest_2413 -1.5 -2.7 Periplasmic protein TonB, links inner and outer membranes compare
Psest_2645 -1.5 -8.0 Transcriptional regulator compare
Psest_1473 -1.5 -7.4 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2018 -1.5 -2.6 Uncharacterized conserved protein compare
Psest_0359 -1.5 -2.2 Transcriptional regulators compare
Psest_4191 -1.5 -3.2 Transcriptional regulator compare
Psest_3322 -1.4 -11.6 TIGR02099 family protein compare
Psest_1837 -1.4 -7.4 Endoglucanase compare
Psest_0673 -1.4 -4.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase compare
Psest_0378 -1.4 -1.8 Lactate dehydrogenase and related dehydrogenases compare
Psest_3701 -1.4 -2.7 3-oxoacyl-(acyl-carrier-protein) synthase compare
Psest_1506 -1.4 -4.1 queuosine biosynthesis protein QueC compare
Psest_0175 -1.4 -6.8 Xaa-Pro aminopeptidase compare
Psest_1464 -1.4 -7.8 Selenocysteine lyase compare
Psest_0708 -1.4 -2.4 outer membrane assembly lipoprotein YfiO compare
Psest_1491 -1.4 -3.8 Cold shock proteins compare
Psest_4284 -1.3 -8.2 Spermidine/putrescine-binding periplasmic protein compare
Psest_2762 -1.3 -3.3 hypothetical protein compare
Psest_1999 -1.3 -1.6 pseudouridine synthase compare
Psest_2581 -1.3 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_1235 -1.3 -6.1 Leucyl aminopeptidase compare
Psest_0094 -1.3 -2.4 Uncharacterized enzyme of phosphonate metabolism compare
Psest_1954 -1.3 -3.7 hypothetical protein compare
Psest_0064 -1.3 -1.6 Transcriptional regulator compare
Psest_2530 -1.2 -4.9 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_1700 -1.2 -4.3 Transcriptional regulator compare
Psest_0449 -1.2 -7.4 Glutamine synthetase adenylyltransferase compare
Psest_1679 -1.2 -1.5 ribonuclease, Rne/Rng family compare
Psest_2527 -1.2 -6.8 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_3399 -1.1 -1.6 Uncharacterized protein conserved in bacteria compare
Psest_3790 -1.1 -6.3 Cytochrome c5 compare
Psest_1417 -1.1 -1.3 hypothetical protein compare
Psest_3494 -1.1 -1.5 hypothetical protein compare
Psest_1518 -1.1 -2.4 tRNA_Ser_CGA compare
Psest_2531 -1.1 -8.2 cytochrome c oxidase accessory protein FixG compare
Psest_3908 -1.1 -1.0 Cytochrome c553 compare
Psest_3307 -1.1 -5.3 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_2862 -1.1 -6.4 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_3129 -1.1 -1.5 tyrosine recombinase XerD compare
Psest_3458 -1.1 -1.4 hypothetical protein compare
Psest_3699 -1.1 -3.6 Dehydrogenases (flavoproteins) compare
Psest_0095 -1.1 -2.1 phosphonate C-P lyase system protein PhnH compare
Psest_4307 -1.1 -2.6 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_4145 -1.0 -2.1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Psest_1099 -1.0 -7.5 Type I restriction-modification system methyltransferase subunit compare
Psest_1920 -1.0 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_0201 -1.0 -2.9 PAS domain S-box compare
Psest_0389 -1.0 -2.0 hypothetical protein compare
Psest_3777 -1.0 -1.9 diguanylate cyclase (GGDEF) domain compare
Psest_4177 -1.0 -1.9 flagellar biosynthetic protein FliP compare
Psest_1516 -1.0 -2.3 Uncharacterized lipoprotein compare
Psest_1619 -1.0 -3.1 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 compare
Psest_2134 -1.0 -7.6 amino acid carrier protein compare
Psest_0550 -1.0 -5.4 Predicted permease, DMT superfamily compare
Psest_1691 -1.0 -3.5 aminodeoxychorismate lyase compare
Psest_2027 -1.0 -6.4 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_3692 -0.9 -1.9 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases compare
Psest_2634 -0.9 -3.3 glycine betaine aldehyde dehydrogenase compare
Psest_2632 -0.9 -3.9 ribosomal protein S12 methylthiotransferase RimO compare
Psest_2327 -0.9 -5.4 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_1012 -0.9 -3.9 Signal transduction histidine kinase compare
Psest_3496 -0.9 -1.1 Predicted metal-binding protein compare
Psest_1488 -0.9 -7.3 outer membrane porin, OprD family. compare
Psest_3905 -0.9 -2.9 formate dehydrogenase, alpha subunit, archaeal-type compare
Psest_1241 -0.9 -3.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Psest_3927 -0.9 -2.8 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_0207 -0.9 -2.1 hypothetical protein compare
Psest_1098 -0.9 -5.4 Restriction endonuclease S subunits compare
Psest_3495 -0.9 -3.2 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Psest_0093 -0.9 -1.7 Uncharacterized enzyme of phosphonate metabolism compare
Psest_3471 -0.9 -3.5 Thermostable hemolysin. compare
Psest_1815 -0.9 -6.5 pseudaminic acid synthase compare
Psest_1509 -0.9 -4.1 quinolinate synthetase complex, A subunit compare
Psest_1750 -0.9 -3.0 Protein of unknown function (DUF2802). compare
Psest_4070 -0.9 -5.7 PAS domain S-box compare
Psest_1768 -0.9 -2.1 thiopurine S-methyltransferase, Se/Te detoxification family compare
Psest_0028 -0.9 -3.1 Coproporphyrinogen III oxidase compare
Psest_1388 -0.9 -1.4 Uncharacterized protein conserved in bacteria compare
Psest_1421 -0.9 -1.5 Glutathione S-transferase compare
Psest_4051 -0.8 -1.6 molybdenum-pterin binding domain compare
Psest_3474 -0.8 -2.1 Short-chain dehydrogenases of various substrate specificities compare
Psest_0281 -0.8 -4.9 Dynamin family. compare
Psest_1268 -0.8 -4.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2216 -0.8 -2.2 Acyl carrier protein compare
Psest_4395 -0.8 -4.8 hypothetical protein compare
Psest_4305 -0.8 -2.6 NAD-dependent aldehyde dehydrogenases compare
Psest_2017 -0.8 -3.0 Predicted acyltransferase compare
Psest_2935 -0.8 -1.9 hypothetical protein compare


Specific Phenotypes

For 13 genes in this experiment

For nitrogen source L-Alanine in Pseudomonas stutzeri RCH2

For nitrogen source L-Alanine across organisms