Experiment set2H22 for Pseudomonas stutzeri RCH2

Compare to:

L-Proline nitrogen source

200 most important genes:

  gene name fitness t score description  
Psest_0153 -6.0 -14.0 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2591 -6.0 -4.1 3-isopropylmalate dehydratase, large subunit compare
Psest_3080 -6.0 -4.1 AraC-type DNA-binding domain-containing proteins compare
Psest_3649 -5.9 -4.1 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3647 -5.8 -6.9 Indole-3-glycerol phosphate synthase compare
Psest_0325 -5.7 -21.5 Putative threonine efflux protein compare
Psest_0152 -5.7 -6.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_0155 -5.7 -6.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3864 -5.6 -14.5 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_2088 -5.5 -3.8 Uncharacterized protein conserved in bacteria compare
Psest_3648 -5.5 -7.5 anthranilate phosphoribosyltransferase compare
Psest_2584 -5.5 -6.5 Phosphoribosylanthranilate isomerase compare
Psest_3650 -5.4 -10.4 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_2578 -5.4 -14.7 O-succinylhomoserine sulfhydrylase compare
Psest_0279 -5.4 -7.3 methionine biosynthesis protein MetW compare
Psest_3721 -5.2 -8.7 Malic enzyme compare
Psest_3079 -5.1 -11.4 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) conserved
Psest_3866 -5.1 -19.6 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3299 -5.0 -14.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_1474 -4.9 -3.4 phosphoribosylaminoimidazole synthetase compare
Psest_3298 -4.9 -11.9 histidinol dehydrogenase compare
Psest_3226 -4.9 -2.2 Predicted membrane protein compare
Psest_2579 -4.8 -9.2 amidophosphoribosyltransferase compare
Psest_0687 -4.8 -9.7 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3944 -4.8 -3.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0062 -4.7 -11.4 tryptophan synthase, alpha subunit compare
Psest_0280 -4.7 -17.9 homoserine O-acetyltransferase compare
Psest_1452 -4.6 -10.3 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_1473 -4.5 -11.3 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2589 -4.5 -15.3 3-isopropylmalate dehydrogenase compare
Psest_0063 -4.3 -7.1 tryptophan synthase, beta subunit compare
Psest_3078 -4.3 -12.5 L-proline:Na+ symporter (from data) conserved
Psest_2590 -4.1 -2.6 3-isopropylmalate dehydratase, small subunit compare
Psest_1772 -4.1 -7.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3931 -4.0 -7.2 Signal transduction histidine kinase, nitrogen specific compare
Psest_3810 -4.0 -3.8 orotate phosphoribosyltransferase compare
Psest_1013 -3.9 -5.3 phosphoribosylamine--glycine ligase compare
Psest_0326 -3.9 -14.2 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_3159 -3.8 -13.6 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0489 -3.7 -5.5 phosphoserine phosphatase SerB compare
Psest_2845 -3.6 -14.8 [Protein-PII] uridylyltransferase compare
Psest_0313 -3.5 -6.3 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3818 -3.5 -10.7 endoribonuclease L-PSP, putative compare
Psest_1295 -3.5 -11.7 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1947 -3.4 -2.4 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2329 -3.4 -19.5 Transcriptional regulator compare
Psest_3932 -3.3 -7.0 nitrogen regulation protein NR(I) compare
Psest_3123 -3.0 -6.6 dihydroorotase, homodimeric type compare
Psest_3998 -3.0 -5.0 glutamate--cysteine ligase compare
Psest_3297 -2.9 -11.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_1037 -2.9 -3.4 acetolactate synthase, small subunit compare
Psest_3338 -2.6 -3.1 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_3943 -2.6 -4.1 Phosphoribosyl-AMP cyclohydrolase compare
Psest_1496 -2.5 -2.9 Holliday junction DNA helicase, RuvA subunit compare
Psest_0952 -2.5 -4.5 Uncharacterized conserved protein compare
Psest_2719 -2.4 -7.8 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_1686 -2.4 -6.7 fatty acid/phospholipid synthesis protein PlsX compare
Psest_0411 -2.2 -12.3 biotin synthetase compare
Psest_2090 -2.2 -6.7 Protein of unknown function (DUF2970). compare
Psest_2104 -2.0 -3.7 IscR-regulated protein YhgI compare
Psest_0953 -1.9 -9.1 iron-sulfur cluster-binding protein compare
Psest_3766 -1.9 -3.9 Uncharacterized protein conserved in bacteria compare
Psest_0212 -1.8 -1.7 exodeoxyribonuclease V, gamma subunit compare
Psest_1505 -1.8 -1.9 Organic radical activating enzymes compare
Psest_2714 -1.8 -2.9 7-cyano-7-deazaguanine reductase compare
Psest_0954 -1.7 -7.5 Fe-S oxidoreductase compare
Psest_2333 -1.7 -1.8 Protein of unknown function (DUF3359). compare
Psest_0958 -1.6 -9.4 Oligoketide cyclase/lipid transport protein compare
Psest_4128 -1.6 -2.8 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_1704 -1.5 -2.2 Dehydrogenases (flavoproteins) compare
Psest_1509 -1.5 -8.1 quinolinate synthetase complex, A subunit compare
Psest_0498 -1.4 -1.9 ribosome small subunit-dependent GTPase A compare
Psest_4191 -1.4 -3.4 Transcriptional regulator compare
Psest_2325 -1.4 -8.6 alpha-L-glutamate ligase-related protein compare
Psest_2324 -1.4 -10.8 hypothetical protein compare
Psest_2945 -1.4 -2.0 septum site-determining protein MinC compare
Psest_0284 -1.3 -9.5 pyridoxal phosphate enzyme, YggS family compare
Psest_2646 -1.3 -3.0 SOS regulatory protein LexA compare
Psest_0718 -1.3 -4.7 nicotinate-nucleotide pyrophosphorylase compare
Psest_2323 -1.3 -9.4 Uncharacterized protein conserved in archaea compare
Psest_1679 -1.3 -2.6 ribonuclease, Rne/Rng family compare
Psest_1640 -1.2 -9.4 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_3075 -1.2 -6.8 sodium/proline symporter compare
Psest_2001 -1.1 -2.4 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_2809 -1.1 -3.8 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_0097 -1.1 -1.7 phosphonates metabolism transcriptional regulator PhnF compare
Psest_0412 -1.1 -7.2 8-amino-7-oxononanoate synthase compare
Psest_1814 -1.1 -7.5 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_3862 -1.0 -8.5 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0415 -1.0 -4.1 dethiobiotin synthase compare
Psest_0998 -1.0 -3.5 poly(A) polymerase compare
Psest_0306 -1.0 -8.0 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0259 -1.0 -1.0 cell division ATP-binding protein FtsE compare
Psest_3178 -1.0 -3.8 formyltetrahydrofolate deformylase compare
Psest_1870 -1.0 -1.9 Transcriptional regulators compare
Psest_0209 -1.0 -1.2 membrane protein AbrB duplication compare
Psest_3339 -1.0 -4.3 Signal transduction histidine kinase compare
Psest_3435 -1.0 -4.8 hypothetical protein compare
Psest_0359 -1.0 -2.3 Transcriptional regulators compare
Psest_0413 -0.9 -5.3 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_2872 -0.9 -2.2 protein RecA compare
Psest_3904 -0.9 -0.9 hypothetical protein compare
Psest_1516 -0.9 -1.8 Uncharacterized lipoprotein compare
Psest_3317 -0.9 -3.4 Phosphotransferase System HPr (HPr) Family compare
Psest_1843 -0.9 -3.2 Uncharacterized Fe-S protein compare
Psest_1277 -0.9 -6.5 2-isopropylmalate synthase, yeast type compare
Psest_1417 -0.9 -1.3 hypothetical protein compare
Psest_4363 -0.9 -5.7 ATPases involved in chromosome partitioning compare
Psest_0170 -0.9 -4.4 5,10-methenyltetrahydrofolate synthetase compare
Psest_2862 -0.9 -5.3 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_1837 -0.9 -5.4 Endoglucanase compare
Psest_1242 -0.9 -2.1 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_3092 -0.9 -1.9 ribonuclease III, bacterial compare
Psest_2532 -0.9 -3.6 Uncharacterized protein conserved in bacteria compare
Psest_1724 -0.9 -3.3 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_2810 -0.8 -3.3 5'/3'-nucleotidase SurE compare
Psest_3146 -0.8 -2.1 hypothetical protein compare
Psest_2791 -0.8 -2.5 hypothetical protein compare
Psest_1813 -0.8 -6.4 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_0508 -0.8 -5.0 gamma-glutamyl phosphate reductase compare
Psest_0414 -0.8 -2.8 biotin biosynthesis protein BioC compare
Psest_2316 -0.8 -6.2 phosphoenolpyruvate synthase compare
Psest_3910 -0.8 -1.1 Uncharacterized protein conserved in bacteria compare
Psest_1031 -0.8 -4.8 Uncharacterized protein conserved in bacteria compare
Psest_3720 -0.8 -6.7 penicillin-binding protein, 1A family compare
Psest_0691 -0.8 -5.9 ribonuclease R compare
Psest_0466 -0.8 -3.1 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1506 -0.7 -3.6 queuosine biosynthesis protein QueC compare
Psest_2581 -0.7 -1.5 Uncharacterized protein conserved in bacteria compare
Psest_3938 -0.7 -1.4 Uncharacterized protein conserved in bacteria compare
Psest_3531 -0.7 -1.3 Peptidase propeptide and YPEB domain. compare
Psest_1486 -0.7 -1.7 hypothetical protein compare
Psest_4310 -0.7 -1.6 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_0154 -0.7 -2.1 Uncharacterized conserved protein compare
Psest_0309 -0.7 -1.2 RND family efflux transporter, MFP subunit compare
Psest_0533 -0.7 -3.3 Sel1 repeat. compare
Psest_3697 -0.7 -0.7 Outer membrane lipoprotein carrier protein LolA. compare
Psest_3843 -0.7 -4.4 4-hydroxybenzoate synthetase (chorismate lyase) compare
Psest_4086 -0.7 -4.8 Transcriptional regulator compare
Psest_2923 -0.7 -1.2 hypothetical protein compare
Psest_3664 -0.7 -1.7 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_1323 -0.7 -2.4 Hydroxypyruvate isomerase compare
Psest_4084 -0.7 -5.7 oxaloacetate decarboxylase alpha subunit compare
Psest_0292 -0.7 -1.9 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_3850 -0.7 -0.9 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_4044 -0.7 -4.0 type I site-specific deoxyribonuclease, HsdR family compare
Psest_0771 -0.7 -5.2 Acyl-CoA hydrolase compare
Psest_3767 -0.7 -2.9 tyrosine recombinase XerC compare
Psest_0281 -0.7 -4.1 Dynamin family. compare
Psest_0182 -0.6 -3.6 glycine cleavage system H protein compare
Psest_4209 -0.6 -1.8 Uncharacterized conserved small protein compare
Psest_1888 -0.6 -0.9 Sua5/YciO/YrdC/YwlC family protein compare
Psest_3168 -0.6 -1.7 Molybdopterin converting factor, large subunit compare
Psest_0558 -0.6 -0.8 urease, beta subunit compare
Psest_1480 -0.6 -2.0 arsenate reductase (glutaredoxin) compare
Psest_3101 -0.6 -5.3 L-aspartate oxidase compare
Psest_3069 -0.6 -2.3 3-oxoadipate enol-lactonase compare
Psest_1492 -0.6 -4.9 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_0951 -0.6 -4.5 FAD/FMN-containing dehydrogenases compare
Psest_4085 -0.6 -4.7 Biotin carboxylase compare
Psest_3988 -0.6 -3.9 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_4010 -0.6 -0.9 peroxiredoxin, OsmC subfamily compare
Psest_0445 -0.6 -4.7 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0137 -0.6 -3.1 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_4396 -0.6 -3.6 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_3860 -0.6 -1.9 Predicted permeases compare
Psest_1326 -0.6 -2.5 Uncharacterized conserved protein compare
Psest_2327 -0.6 -3.0 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_2343 -0.6 -2.5 Mg-dependent DNase compare
Psest_3304 -0.6 -2.9 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_2243 -0.6 -0.8 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_2022 -0.6 -2.5 ADP-ribose pyrophosphatase compare
Psest_4287 -0.6 -3.1 Predicted glutamine amidotransferases compare
Psest_0015 -0.6 -1.2 Tetratricopeptide repeat. compare
Psest_3840 -0.6 -1.9 D-lactate/glycolate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_3145 -0.5 -1.2 hypothetical protein compare
Psest_1498 -0.5 -1.9 tol-pal system-associated acyl-CoA thioesterase compare
Psest_4149 -0.5 -2.3 fagellar hook-basal body proteins compare
Psest_3129 -0.5 -1.0 tyrosine recombinase XerD compare
Psest_2334 -0.5 -4.5 Uncharacterized protein conserved in bacteria compare
Psest_2285 -0.5 -2.5 ATP-dependent protease La compare
Psest_2647 -0.5 -1.9 SOS-response cell division inhibitor, blocks FtsZ ring formation compare
Psest_1872 -0.5 -2.5 selT/selW/selH selenoprotein domain compare
Psest_1470 -0.5 -4.4 succinyldiaminopimelate transaminase compare
Psest_4051 -0.5 -1.3 molybdenum-pterin binding domain compare
Psest_1582 -0.5 -1.2 Protein of unknown function (DUF3087). compare
Psest_1306 -0.5 -1.0 hypothetical protein compare
Psest_0136 -0.5 -4.3 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_2645 -0.5 -3.4 Transcriptional regulator compare
Psest_3495 -0.5 -2.0 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Psest_3645 -0.5 -3.9 Predicted redox protein, regulator of disulfide bond formation compare
Psest_0297 -0.5 -1.8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0094 -0.5 -0.8 Uncharacterized enzyme of phosphonate metabolism compare
Psest_1812 -0.5 -3.8 pseudaminic acid CMP-transferase compare
Psest_3698 -0.5 -1.5 Predicted exporter compare
Psest_2232 -0.5 -4.3 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_1292 -0.5 -3.0 monothiol glutaredoxin, Grx4 family compare
Psest_1752 -0.5 -0.9 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB compare
Psest_1478 -0.5 -3.1 Predicted membrane protein compare
Psest_2000 -0.5 -2.3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen source L-Proline in Pseudomonas stutzeri RCH2

For nitrogen source L-Proline across organisms