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Experiment set28IT076 for
Klebsiella michiganensis M5al
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Parafilmed volatile agar plate with no fungus
200 most detrimental genes:
gene
name
fitness
t score
description
BWI76
_RS16000
+5.0
9.6
multidrug transporter subunit MdtI
compare
BWI76
_RS02725
+4.5
6.4
HxlR family transcriptional regulator
compare
BWI76
_RS22935
+4.3
1.8
L-fucose mutarotase
compare
BWI76
_RS11430
+4.3
6.6
lipoprotein
compare
BWI76
_RS12040
+4.1
7.0
hypothetical protein
compare
BWI76
_RS05790
+4.0
7.9
phage DNA-binding protein
compare
BWI76
_RS06525
+4.0
17.5
ATP-dependent Clp protease proteolytic subunit
compare
BWI76
_RS21140
+3.6
2.6
molecular chaperone HscA
compare
BWI76
_RS06530
+3.3
7.1
ATP-dependent Clp protease ATP-binding subunit ClpX
compare
BWI76
_RS09255
+2.5
1.4
hypothetical protein
compare
BWI76
_RS12170
+2.4
1.8
hypothetical protein
compare
BWI76
_RS09390
+2.3
2.2
phage tail protein
compare
BWI76
_RS26065
+2.3
1.4
phosphoglycolate phosphatase
compare
BWI76
_RS02870
+2.2
3.9
hypothetical protein
compare
BWI76
_RS27780
+2.2
1.0
hypothetical protein
compare
BWI76
_RS13290
+2.2
3.7
protocatechuate 3,4-dioxygenase subunit beta
compare
BWI76
_RS18140
+2.1
2.3
zinc ABC transporter permease
compare
BWI76
_RS17525
+2.1
2.3
XshC-Cox1-family protein
compare
BWI76
_RS03005
+2.1
2.3
hypothetical protein
compare
BWI76
_RS03700
+2.0
3.1
hypothetical protein
compare
BWI76
_RS13110
+2.0
1.5
phenylacetic acid degradation protein
compare
BWI76
_RS16095
+2.0
0.9
thiamine biosynthesis protein ApbE
compare
BWI76
_RS07895
+2.0
1.9
sugar ABC transporter ATPase
compare
BWI76
_RS08215
+2.0
1.4
glucosamine-6-phosphate deaminase
compare
BWI76
_RS08650
+1.9
2.3
molybdate ABC transporter permease
compare
BWI76
_RS13370
+1.9
1.1
hypothetical protein
compare
BWI76
_RS24005
+1.9
4.5
cobalt ABC transporter ATP-binding protein
compare
BWI76
_RS07255
+1.9
1.9
hypothetical protein
compare
BWI76
_RS20800
+1.9
1.2
carboxysome shell protein
compare
BWI76
_RS08645
+1.9
3.9
molybdate ABC transporter substrate-binding protein
compare
BWI76
_RS16025
+1.9
1.9
triphosphoribosyl-dephospho-CoA synthase
compare
BWI76
_RS04275
+1.8
7.7
molybdopterin adenylyltransferase
compare
BWI76
_RS24280
+1.8
1.1
biopolymer transporter ExbB
compare
BWI76
_RS00085
+1.8
1.4
hypothetical protein
compare
BWI76
_RS15705
+1.8
2.0
putative holin protein
compare
BWI76
_RS07855
+1.7
1.3
PucR family transcriptional regulator
compare
BWI76
_RS11005
+1.7
2.8
MFS transporter
compare
BWI76
_RS18410
+1.7
1.8
drug/metabolite exporter YedA
compare
BWI76
_RS00885
+1.7
1.7
tRNA (uridine(54)-C5)-methyltransferase TrmA
compare
BWI76
_RS20940
+1.7
1.8
uracil/xanthine transporter
compare
BWI76
_RS09250
+1.7
2.3
hypothetical protein
compare
BWI76
_RS03740
+1.7
3.2
hypothetical protein
compare
BWI76
_RS11980
+1.6
1.4
DeoR family transcriptional regulator
compare
BWI76
_RS24655
+1.6
1.0
autoinducer 2 ABC transporter permease LsrC
compare
BWI76
_RS12985
+1.6
2.1
transcriptional regulator
compare
BWI76
_RS16990
+1.6
1.5
ABC transporter ATP-binding protein
compare
BWI76
_RS08510
+1.6
1.6
cyd operon protein YbgE
compare
BWI76
_RS19885
+1.6
2.0
multidrug ABC transporter permease/ATP-binding protein
compare
BWI76
_RS04240
+1.6
3.5
thr operon leader peptide
compare
BWI76
_RS08815
+1.6
6.1
cyclic pyranopterin phosphate synthase
compare
BWI76
_RS13265
+1.6
1.8
hypothetical protein
compare
BWI76
_RS12205
+1.5
3.8
hypothetical protein
compare
BWI76
_RS13315
+1.5
2.9
50S ribosomal protein L7/L12-serine acetyltransferase
compare
BWI76
_RS01755
+1.5
1.6
23S rRNA pseudouridine synthase F
compare
BWI76
_RS06745
+1.5
1.1
N-acetyltransferase GCN5
compare
BWI76
_RS17715
+1.5
1.4
murein transglycosylase
compare
BWI76
_RS24880
+1.5
2.3
PTS galactitol transporter subunit IIA
compare
BWI76
_RS07070
+1.5
0.8
5-(carboxyamino)imidazole ribonucleotide mutase
compare
BWI76
_RS06340
+1.5
1.3
hypothetical protein
compare
BWI76
_RS09725
+1.4
1.4
MurR/RpiR family transcriptional regulator
compare
BWI76
_RS15925
+1.4
3.2
dimethyl sulfoxide reductase subunit A
compare
BWI76
_RS23195
+1.4
1.9
ethanolamine utilization protein EutP
compare
BWI76
_RS16775
+1.4
2.3
malate/lactate/ureidoglycolate dehydrogenase
compare
BWI76
_RS08835
+1.4
4.3
molybdopterin guanine dinucleotide biosynthesis protein MoaE
compare
BWI76
_RS23240
+1.4
0.9
exonuclease V subunit gamma
compare
BWI76
_RS15670
+1.4
1.3
hypothetical protein
compare
BWI76
_RS16055
+1.4
1.8
malonate decarboxylase subunit epsilon
compare
BWI76
_RS10950
+1.4
0.8
MFS transporter
compare
BWI76
_RS20830
+1.4
1.5
bifunctional malic enzyme oxidoreductase/phosphotransacetylase
compare
BWI76
_RS08825
+1.4
3.3
cyclic pyranopterin monophosphate synthase MoaC
compare
BWI76
_RS11470
+1.3
2.5
sensor domain-containing diguanylate cyclase
compare
BWI76
_RS05555
+1.3
2.2
Crl family RNA polymerase assembly factor
compare
BWI76
_RS17530
+1.3
3.0
hypothetical protein
compare
BWI76
_RS12375
+1.3
1.0
DNA-invertase hin
compare
BWI76
_RS17770
+1.3
1.9
isomerase/hydrolase
compare
BWI76
_RS24275
+1.3
0.9
biopolymer transport protein ExbD
compare
BWI76
_RS09130
+1.3
1.2
biofilm formation regulatory protein BssR
compare
BWI76
_RS26980
+1.3
1.5
cold-shock protein
compare
BWI76
_RS18425
+1.3
3.5
phosphohydrolase
compare
BWI76
_RS19505
+1.3
2.5
ABC transporter substrate-binding protein
compare
BWI76
_RS13610
+1.3
1.0
sugar transporter
compare
BWI76
_RS27225
+1.3
1.4
rhodanese-like domain-containing protein
compare
BWI76
_RS01030
+1.3
2.3
cytosine/purine, uracil, thiamine, allantoin permease family protein
compare
BWI76
_RS08380
+1.3
0.8
endonuclease VIII
compare
BWI76
_RS27015
+1.3
1.3
hypothetical protein
compare
BWI76
_RS07810
+1.2
1.4
sugar ABC transporter periplasmic sugar-binding protein
compare
BWI76
_RS13585
+1.2
2.0
4-oxalocrotonate tautomerase
compare
BWI76
_RS20525
+1.2
1.2
glyceraldehyde 3-phosphate reductase
compare
BWI76
_RS16195
+1.2
1.0
hypothetical protein
compare
BWI76
_RS18485
+1.2
1.9
LysR family transcriptional regulator
compare
BWI76
_RS09680
+1.2
2.4
dimethyl sulfoxide reductase subunit A
compare
BWI76
_RS25975
+1.2
2.7
phosphoribulokinase
compare
BWI76
_RS19355
+1.2
2.0
LacI family transcriptional regulator
compare
BWI76
_RS09085
+1.2
4.6
molybdopterin molybdenumtransferase MoeA
compare
BWI76
_RS17290
+1.2
1.3
formyltetrahydrofolate deformylase
compare
BWI76
_RS05640
+1.2
0.8
GntR family transcriptional regulator
compare
BWI76
_RS16490
+1.2
2.2
glutaredoxin
compare
BWI76
_RS25230
+1.2
1.0
phospholipid ABC transporter ATP-binding protein MlaF
compare
BWI76
_RS00330
+1.2
3.6
molybdenum cofactor guanylyltransferase
compare
BWI76
_RS11435
+1.2
1.3
hypothetical protein
compare
BWI76
_RS09295
+1.2
1.2
hypothetical protein
compare
BWI76
_RS11170
+1.2
1.3
hypothetical protein
compare
BWI76
_RS22020
+1.2
1.3
L-alanine exporter AlaE
compare
BWI76
_RS10915
+1.2
1.5
O-acetyl-ADP-ribose deacetylase
compare
BWI76
_RS09080
+1.2
1.7
molybdopterin-synthase adenylyltransferase MoeB
compare
BWI76
_RS23230
+1.2
0.8
exodeoxyribonuclease V subunit beta
compare
BWI76
_RS26115
+1.2
2.6
hypothetical protein
compare
BWI76
_RS12335
+1.2
2.8
hypothetical protein
compare
BWI76
_RS20565
+1.2
1.8
hypothetical protein
compare
BWI76
_RS00295
+1.1
1.8
transcriptional regulator RbsR
compare
BWI76
_RS27430
+1.1
0.8
(p)ppGpp synthetase
compare
BWI76
_RS20490
+1.1
2.0
hypothetical protein
compare
BWI76
_RS15265
+1.1
1.6
hypothetical protein
compare
BWI76
_RS14735
+1.1
1.3
type 11 methyltransferase
compare
BWI76
_RS10850
+1.1
1.2
two-component sensor histidine kinase
compare
BWI76
_RS06975
+1.1
2.0
DNA-binding transcriptional activator AllS
compare
BWI76
_RS24485
+1.1
1.4
bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase
compare
BWI76
_RS21955
+1.1
1.6
transferase
compare
BWI76
_RS16190
+1.1
2.2
universal stress protein UspE
compare
BWI76
_RS03170
+1.1
1.1
hypothetical protein
compare
BWI76
_RS24020
+1.1
2.4
peptidase M48
compare
BWI76
_RS04175
+1.1
0.9
energy-dependent translational throttle protein EttA
compare
BWI76
_RS22980
+1.1
1.6
murein transglycosylase A
compare
BWI76
_RS23020
+1.1
1.3
cobalamin biosynthesis protein CbiQ
compare
BWI76
_RS08785
+1.1
1.3
excinuclease ABC subunit B
compare
BWI76
_RS10300
+1.1
1.3
MFS transporter
compare
BWI76
_RS21180
+1.1
2.2
nickel transporter
compare
BWI76
_RS25160
+1.1
1.4
transcription elongation factor GreA
compare
BWI76
_RS26440
+1.1
1.0
hypothetical protein
compare
BWI76
_RS05045
+1.1
2.3
general secretion pathway protein GspM
compare
BWI76
_RS12565
+1.1
1.8
SAM-dependent methyltransferase
compare
BWI76
_RS14575
+1.1
1.0
TENA/THI-4 family protein
compare
BWI76
_RS04540
+1.1
2.0
molecular chaperone DjlA
compare
BWI76
_RS02235
+1.1
2.1
VOC family protein
compare
BWI76
_RS10060
+1.1
1.1
acylphosphatase
compare
BWI76
_RS13950
+1.1
1.3
hypothetical protein
compare
BWI76
_RS07530
+1.1
2.3
binding-protein-dependent transport system inner membrane protein
compare
BWI76
_RS06225
+1.1
1.4
exonuclease sbcCD subunit D
compare
BWI76
_RS16830
+1.0
1.6
ABC transporter
compare
BWI76
_RS15940
+1.0
2.1
DMSO reductase maturation protein DsmD
compare
BWI76
_RS13845
+1.0
0.9
LysR family transcriptional regulator
compare
BWI76
_RS18630
+1.0
1.7
nitrogen assimilation transcriptional regulator
compare
BWI76
_RS23715
+1.0
2.1
2-deoxy-D-ribonate transporter 1
(from data)
compare
BWI76
_RS10450
+1.0
1.1
tRNA-Tyr
compare
BWI76
_RS20540
+1.0
1.2
NupC/NupG family nucleoside CNT transporter
compare
BWI76
_RS11500
+1.0
1.5
D-hexose-6-phosphate mutarotase
compare
BWI76
_RS12755
+1.0
2.9
hypothetical protein
compare
BWI76
_RS23400
+1.0
1.0
oligogalacturonide lyase
compare
BWI76
_RS24385
+1.0
5.1
phosphodiesterase
compare
BWI76
_RS17620
+1.0
1.7
ABC transporter ATP-binding protein
compare
BWI76
_RS13770
+1.0
1.6
alkylhydroperoxidase domain protein
compare
BWI76
_RS02430
+1.0
1.6
multidrug transporter
compare
BWI76
_RS22095
+1.0
1.5
multidrug export protein EmrA
compare
BWI76
_RS15035
+1.0
1.4
metal ABC transporter permease
compare
BWI76
_RS08660
+1.0
1.2
pyridoxal phosphatase
compare
BWI76
_RS14770
+1.0
1.0
PTS IIA 2 domain protein
compare
BWI76
_RS00745
+1.0
4.5
1,4-dihydroxy-2-naphthoate polyprenyltransferase
compare
BWI76
_RS16470
+1.0
1.1
transcriptional repressor NemR
compare
BWI76
_RS23245
+1.0
2.4
hypothetical protein
compare
BWI76
_RS26290
+1.0
0.8
glycerol-3-phosphate ABC transporter ATP-binding protein
compare
BWI76
_RS22690
+1.0
0.8
adenylyl-sulfate kinase
compare
BWI76
_RS06670
+1.0
1.5
hypothetical protein
compare
BWI76
_RS14525
+0.9
2.0
AraC family transcriptional regulator
compare
BWI76
_RS13605
+0.9
2.4
porin
compare
BWI76
_RS12435
+0.9
1.6
putative amino acid amidohydrolase
compare
BWI76
_RS08655
+0.9
2.0
molybdenum ABC transporter ATP-binding protein
compare
BWI76
_RS14650
+0.9
1.8
helix-turn-helix transcriptional regulator
compare
BWI76
_RS14375
+0.9
1.8
hypothetical protein
compare
BWI76
_RS13505
+0.9
1.5
putative receptor
compare
BWI76
_RS25060
+0.9
1.8
lipoprotein NlpI
compare
BWI76
_RS16695
+0.9
1.3
dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein
compare
BWI76
_RS12385
+0.9
1.7
DNA polymerase V subunit UmuC
compare
BWI76
_RS19580
+0.9
0.8
FAA-hydrolase
compare
BWI76
_RS05025
+0.9
1.1
2'-5' RNA ligase
compare
BWI76
_RS22645
+0.9
2.4
RNA polymerase sigma factor RpoS
compare
BWI76
_RS12225
+0.9
1.0
hypothetical protein
compare
BWI76
_RS15450
+0.9
1.2
hypothetical protein
compare
BWI76
_RS14280
+0.9
1.7
hypothetical protein
compare
BWI76
_RS17180
+0.9
1.3
hypothetical protein
compare
BWI76
_RS13095
+0.9
1.1
phenylacetate-CoA oxygenase subunit PaaB
compare
BWI76
_RS15045
+0.9
1.6
LysR family transcriptional regulator
compare
BWI76
_RS19360
+0.9
1.4
glucose dehydrogenase
compare
BWI76
_RS14350
+0.9
1.6
hypothetical protein
compare
BWI76
_RS19605
+0.9
1.0
CidB/LrgB family autolysis modulator
compare
BWI76
_RS09535
+0.9
1.7
N-acetylmuramoyl-L-alanine amidase amid
compare
BWI76
_RS26055
+0.9
1.8
siroheme synthase
compare
BWI76
_RS19200
+0.9
1.6
binding-protein-dependent transport system inner membrane protein
compare
BWI76
_RS07805
+0.9
1.0
sugar ABC transporter permease
compare
BWI76
_RS20410
+0.9
1.2
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC
compare
BWI76
_RS00325
+0.9
1.1
molybdopterin-guanine dinucleotide biosynthesis protein MobB
compare
BWI76
_RS09405
+0.9
2.5
hypothetical protein
compare
BWI76
_RS12210
+0.9
0.8
hypothetical protein
compare
BWI76
_RS26990
+0.9
1.8
protein HokA
compare
BWI76
_RS14330
+0.9
3.2
IS3 family transposase
compare
BWI76
_RS25635
+0.9
2.3
gamma carbonic anhydrase family protein
compare
BWI76
_RS14645
+0.9
1.4
sensor histidine kinase
compare
BWI76
_RS13630
+0.9
1.2
ABC transporter
compare
BWI76
_RS19480
+0.9
1.3
transcriptional regulator
compare
BWI76
_RS19100
+0.9
1.1
putative acid phosphatase
compare
BWI76
_RS20795
+0.9
0.7
ethanolamine catabolic microcompartment shell protein EutN
compare
Specific Phenotypes
For 2 genes in this experiment