Experiment set24S399 for Pseudomonas fluorescens FW300-N2E2

Compare to:

Ying_Nucleobase14 rep C; time point 1

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3783 -4.6 -7.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_2074 -3.7 -4.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3782 -3.2 -9.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3661 -3.0 -15.3 hypothetical protein compare
Pf6N2E2_3932 -2.9 -3.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3842 -2.8 -4.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2822 -2.7 -6.5 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_71 -2.7 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_63 -2.6 -5.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4473 -2.6 -10.7 HlyD family secretion protein compare
Pf6N2E2_3630 -2.5 -4.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_77 -2.5 -3.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3610 -2.5 -2.4 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_64 -2.5 -1.7 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5177 -2.3 -5.2 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4048 -2.3 -4.2 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4826 -2.3 -4.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3645 -2.3 -12.5 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_5761 -2.3 -1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_2674 -2.2 -0.9 FIG00953856: hypothetical protein compare
Pf6N2E2_3751 -2.2 -7.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3240 -2.2 -0.9 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_5803 -2.1 -6.4 Allantoicase (EC 3.5.3.4) compare
Pf6N2E2_3687 -2.1 -1.4 FIG00959437: hypothetical protein compare
Pf6N2E2_2139 -2.1 -3.7 Paraquat-inducible protein A compare
Pf6N2E2_3752 -2.1 -11.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_2675 -2.0 -0.8 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_3984 -2.0 -11.2 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_4596 -2.0 -4.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3940 -2.0 -10.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_66 -2.0 -4.7 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3253 -2.0 -3.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2753 -2.0 -5.0 HtrA protease/chaperone protein compare
Pf6N2E2_4590 -2.0 -4.3 Thiazole biosynthesis protein ThiG compare
Pf6N2E2_1709 -1.9 -1.3 multidrug resistance transporter, Bcr/CflA family compare
Pf6N2E2_4825 -1.9 -3.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_5679 -1.8 -5.1 hypothetical protein compare
Pf6N2E2_4541 -1.8 -1.1 hypothetical protein compare
Pf6N2E2_2073 -1.8 -5.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_6099 -1.8 -0.7 tRNA-Glu-TTC compare
Pf6N2E2_4471 -1.8 -6.5 ABC-type multidrug transport system, permease component compare
Pf6N2E2_3252 -1.8 -3.6 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2561 -1.8 -1.2 FIG00955434: hypothetical protein compare
Pf6N2E2_848 -1.8 -1.7 hypothetical protein compare
Pf6N2E2_5622 -1.8 -1.2 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_3839 -1.8 -1.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_2071 -1.8 -1.1 hypothetical protein compare
Pf6N2E2_5455 -1.7 -1.1 hypothetical protein compare
Pf6N2E2_482 -1.7 -1.1 Transcriptional regulator BkdR of isoleucine and valine catabolism operon compare
Pf6N2E2_2320 -1.7 -6.8 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_2080 -1.7 -1.0 hypothetical protein compare
Pf6N2E2_4597 -1.7 -2.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3644 -1.7 -8.0 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) compare
Pf6N2E2_5258 -1.7 -3.6 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2318 -1.7 -13.9 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2487 -1.6 -0.6 FIG00956090: hypothetical protein compare
Pf6N2E2_2473 -1.6 -0.6 Major outer membrane lipoprotein I compare
Pf6N2E2_4990 -1.6 -1.0 Uncharacterized protein, similar to the N-terminal domain of Lon protease compare
Pf6N2E2_3659 -1.6 -8.0 Protein fixF compare
Pf6N2E2_4710 -1.6 -1.0 hypothetical protein compare
Pf6N2E2_6035 -1.6 -1.0 alpha/beta hydrolase fold compare
Pf6N2E2_1834 -1.6 -1.2 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_5223 -1.6 -4.5 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_339 -1.5 -1.0 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_4472 -1.5 -9.7 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5647 -1.5 -2.8 Transcriptional regulator, TetR family compare
Pf6N2E2_953 -1.5 -1.0 FIG00958851: hypothetical protein compare
Pf6N2E2_3573 -1.5 -1.0 HupE-UreJ family metal transporter compare
Pf6N2E2_2418 -1.5 -2.7 DNA-binding response regulator, LuxR family compare
Pf6N2E2_4969 -1.5 -0.6 hypothetical protein compare
Pf6N2E2_5257 -1.5 -7.1 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5023 -1.5 -1.0 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) compare
Pf6N2E2_1885 -1.5 -1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_500 -1.5 -1.4 Beta-ureidopropionase (EC 3.5.1.6) compare
Pf6N2E2_3763 -1.5 -0.9 hypothetical protein compare
Pf6N2E2_5838 -1.5 -4.4 Hydroxypyruvate isomerase (EC 5.3.1.22) compare
Pf6N2E2_2258 -1.4 -4.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_4171 -1.4 -1.0 hypothetical protein compare
Pf6N2E2_3853 -1.4 -1.6 hypothetical protein compare
Pf6N2E2_1740 -1.4 -2.1 Transketolase, C-terminal section (EC 2.2.1.1) compare
Pf6N2E2_4564 -1.4 -4.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4762 -1.4 -0.9 Biotin synthesis protein BioH compare
Pf6N2E2_5024 -1.4 -0.9 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) compare
Pf6N2E2_3179 -1.4 -0.9 FIG021952: putative membrane protein compare
Pf6N2E2_2235 -1.3 -5.5 Xanthine permease compare
Pf6N2E2_4077 -1.3 -0.9 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_74 -1.3 -0.8 DedD protein compare
Pf6N2E2_5175 -1.3 -3.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_1916 -1.3 -1.7 Transcriptional regulator, LysR family compare
Pf6N2E2_1412 -1.3 -0.8 hypothetical protein compare
Pf6N2E2_3537 -1.2 -1.6 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_3849 -1.2 -1.1 FIG00954739: hypothetical protein compare
Pf6N2E2_5807 -1.2 -1.2 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare
Pf6N2E2_3170 -1.2 -4.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_160 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_469 -1.2 -0.8 lipoprotein, putative compare
Pf6N2E2_4181 -1.2 -0.5 Organic hydroperoxide resistance protein compare
Pf6N2E2_2064 -1.2 -0.8 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_1749 -1.2 -1.1 Cyn operon transcriptional activator compare
Pf6N2E2_1959 -1.2 -0.8 D-sorbitol dehydrogenase (EC 1.1.1.14) (from data) compare
Pf6N2E2_302 -1.2 -3.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3134 -1.2 -0.7 hypothetical protein compare
Pf6N2E2_2423 -1.2 -6.2 Molybdenum cofactor biosynthesis protein MoaB compare
Pf6N2E2_2507 -1.2 -3.9 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_4727 -1.2 -1.1 Cold shock protein CspD compare
Pf6N2E2_99 -1.2 -1.3 hypothetical protein compare
Pf6N2E2_734 -1.2 -0.8 Molybdenum cofactor biosynthesis protein MoaA compare
Pf6N2E2_2506 -1.2 -6.0 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_4732 -1.2 -0.8 hypothetical protein compare
Pf6N2E2_1803 -1.2 -0.8 Polysaccharide deacetylase compare
Pf6N2E2_4773 -1.2 -0.7 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_3748 -1.2 -1.3 Cytochrome B561 compare
Pf6N2E2_2162 -1.2 -1.1 Cytochrome c4 compare
Pf6N2E2_472 -1.2 -0.8 FKBP-type peptidyl-prolyl cis-trans isomerase compare
Pf6N2E2_5780 -1.1 -3.8 Periplasmic protease compare
Pf6N2E2_2769 -1.1 -1.5 Tricarboxylate transport protein TctB compare
Pf6N2E2_1024 -1.1 -1.0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases compare
Pf6N2E2_3428 -1.1 -0.8 hypothetical protein compare
Pf6N2E2_5419 -1.1 -0.7 DNA polymerase III chi subunit (EC 2.7.7.7) compare
Pf6N2E2_2324 -1.1 -1.6 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
Pf6N2E2_4300 -1.1 -1.7 Uncharacterized protein similar to VCA0109 compare
Pf6N2E2_2778 -1.1 -0.7 Urea carboxylase-related aminomethyltransferase (EC 2.1.2.10) compare
Pf6N2E2_2256 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_5950 -1.1 -2.3 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_5805 -1.1 -3.3 Uricase (urate oxidase) (EC 1.7.3.3) compare
Pf6N2E2_2752 -1.1 -2.9 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_5802 -1.1 -5.1 Ureidoglycolate hydrolase (EC 3.5.3.19) compare
Pf6N2E2_5703 -1.1 -1.0 outer membrane protein H1 compare
Pf6N2E2_2440 -1.1 -0.6 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_1490 -1.1 -1.0 hypothetical protein compare
Pf6N2E2_3198 -1.1 -0.7 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
Pf6N2E2_4715 -1.1 -0.7 Low-specificity L-threonine aldolase (EC 4.1.2.48) compare
Pf6N2E2_4752 -1.1 -7.3 Malate synthase G (EC 2.3.3.9) compare
Pf6N2E2_443 -1.1 -0.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_453 -1.1 -0.7 LysR family transcriptional regulator STM2281 compare
Pf6N2E2_3658 -1.1 -8.7 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_2552 -1.1 -3.4 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_5756 -1.1 -0.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_537 -1.1 -1.4 Na(+) H(+) antiporter subunit C compare
Pf6N2E2_2849 -1.1 -0.7 Chromosome initiation inhibitor compare
Pf6N2E2_4818 -1.1 -0.7 Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) compare
Pf6N2E2_3897 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_660 -1.1 -0.7 hypothetical protein compare
Pf6N2E2_1028 -1.1 -0.7 Transcriptional regulator, LysR family compare
Pf6N2E2_1526 -1.1 -1.4 MgtC family compare
Pf6N2E2_1705 -1.1 -0.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_278 -1.1 -1.6 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf6N2E2_2337 -1.1 -6.5 Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4) compare
Pf6N2E2_6085 -1.1 -0.7 Aha1 domain superfamily compare
Pf6N2E2_3852 -1.1 -0.7 Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-) compare
Pf6N2E2_4307 -1.0 -1.4 Type VI secretion lipoprotein/VasD compare
Pf6N2E2_1452 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_3221 -1.0 -0.7 FIG00352444: hypothetical protein compare
Pf6N2E2_2508 -1.0 -2.7 hypothetical protein compare
Pf6N2E2_1089 -1.0 -0.6 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_1905 -1.0 -0.9 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) compare
Pf6N2E2_3912 -1.0 -0.7 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
Pf6N2E2_1381 -1.0 -2.1 Aldehyde dehydrogenase (EC 1.2.1.3) compare
Pf6N2E2_5328 -1.0 -1.3 FIG00958649: hypothetical protein compare
Pf6N2E2_1875 -1.0 -0.7 Protoporphyrinogen oxidase (EC 1.3.3.4) compare
Pf6N2E2_4177 -1.0 -1.3 hypothetical protein compare
Pf6N2E2_4631 -1.0 -1.0 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf6N2E2_3169 -1.0 -0.7 Membrane proteins related to metalloendopeptidases compare
Pf6N2E2_4047 -1.0 -0.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_101 -1.0 -1.5 CigR (Putative inner membrane protein) compare
Pf6N2E2_165 -1.0 -0.6 Ribokinase (EC 2.7.1.15) compare
Pf6N2E2_5720 -1.0 -0.7 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_5517 -1.0 -1.0 Glutathione S-transferase (EC 2.5.1.18) compare
Pf6N2E2_217 -1.0 -1.1 Signal transduction histidine kinase compare
Pf6N2E2_4761 -1.0 -0.7 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf6N2E2_5013 -1.0 -1.4 Putative membrane protein compare
Pf6N2E2_3559 -1.0 -1.4 Putative heat shock protein YegD compare
Pf6N2E2_6046 -1.0 -1.5 hypothetical protein compare
Pf6N2E2_16 -1.0 -0.4 hypothetical protein compare
Pf6N2E2_3720 -1.0 -0.6 FIG027190: Putative transmembrane protein compare
Pf6N2E2_5599 -1.0 -0.6 Electron transport complex protein RnfA compare
Pf6N2E2_5366 -1.0 -1.3 DNA-binding heavy metal response regulator compare
Pf6N2E2_2986 -1.0 -0.9 Transcriptional regulator, LuxR family compare
Pf6N2E2_5111 -1.0 -0.6 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_552 -1.0 -0.6 Uncharacterized protein ImpF compare
Pf6N2E2_1743 -1.0 -1.2 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_5613 -1.0 -1.1 FIG00953674: hypothetical protein compare
Pf6N2E2_1399 -1.0 -0.6 Transcriptional regulator, LuxR family compare
Pf6N2E2_4254 -1.0 -1.5 HflK protein compare
Pf6N2E2_2688 -1.0 -1.4 YD repeat protein compare
Pf6N2E2_62 -1.0 -1.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3862 -1.0 -1.5 hypothetical protein compare
Pf6N2E2_1258 -1.0 -0.9 FIG00960119: hypothetical protein compare
Pf6N2E2_466 -1.0 -0.9 Nicotinamidase (EC 3.5.1.19) compare
Pf6N2E2_4824 -1.0 -2.7 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_3810 -1.0 -0.6 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_1981 -1.0 -0.6 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_237 -1.0 -0.6 hypothetical protein compare
Pf6N2E2_5272 -1.0 -1.1 Dihydroneopterin triphosphate epimerase compare
Pf6N2E2_2396 -1.0 -1.1 Sensor histidine kinase compare
Pf6N2E2_4779 -1.0 -1.2 Transcriptional regulator, AsnC family compare
Pf6N2E2_55 -0.9 -0.6 Probable hydrolase compare
Pf6N2E2_5394 -0.9 -3.0 Molybdenum cofactor biosynthesis protein MoaE compare
Pf6N2E2_595 -0.9 -0.6 Arsenical resistance operon repressor compare
Pf6N2E2_3663 -0.9 -6.0 Glycosyl transferase compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source Ying_Nucleobase14 in Pseudomonas fluorescens FW300-N2E2

For carbon source Ying_Nucleobase14 across organisms