Experiment set22IT045 for Pseudomonas fluorescens SBW25-INTG

Compare to:

L-Valine 10 mM carbon source

200 most important genes:

  gene name fitness t score description  
PFLU_RS10765 -12.2 -27.3 UvrY/SirA/GacA family response regulator transcription factor compare
PFLU_RS18410 -10.0 -6.3 response regulator compare
PFLU_RS19015 -7.6 -16.1 anti-sigma factor compare
PFLU_RS06430 -6.2 -27.7 RNA polymerase sigma factor RpoS compare
PFLU_RS21530 -5.6 -24.7 transporter substrate-binding domain-containing protein compare
PFLU_RS29290 -5.3 -9.5 hypothetical protein compare
PFLU_RS14775 -5.3 -2.2 enoyl-CoA hydratase compare
PFLU_RS29780 -4.5 -6.9 acyl-CoA thioesterase compare
PFLU_RS28695 -4.5 -4.3 phosphoglycerate dehydrogenase compare
PFLU_RS20575 -4.4 -4.3 3-isopropylmalate dehydratase small subunit compare
PFLU_RS19375 -4.4 -5.3 branched-chain amino acid aminotransferase compare
PFLU_RS20290 -4.2 -1.7 integration host factor subunit alpha compare
PFLU_RS18725 -4.2 -1.7 alpha/beta hydrolase compare
PFLU_RS28385 -4.1 -6.9 homoserine O-acetyltransferase compare
PFLU_RS14780 -4.1 -4.9 acyl-CoA dehydrogenase conserved
PFLU_RS20565 -4.1 -2.8 3-isopropylmalate dehydrogenase compare
PFLU_RS19370 -4.1 -6.2 dihydrolipoyl dehydrogenase conserved
PFLU_RS25535 -4.0 -3.9 3-hydroxyisobutyrate dehydrogenase conserved
PFLU_RS29885 -4.0 -8.1 LysR family transcriptional regulator compare
PFLU_RS28390 -4.0 -6.1 methionine biosynthesis protein MetW compare
PFLU_RS24825 -4.0 -2.5 Fe-S cluster assembly protein IscX compare
PFLU_RS04465 -4.0 -4.7 ATP phosphoribosyltransferase compare
PFLU_RS24025 -4.0 -7.6 quinolinate synthase NadA compare
PFLU_RS25545 -3.9 -6.6 LysR family transcriptional regulator conserved
PFLU_RS22685 -3.9 -5.4 2-methylcitrate synthase conserved
PFLU_RS29875 -3.9 -9.8 oxaloacetate decarboxylase subunit alpha compare
PFLU_RS25540 -3.8 -4.6 CoA-acylating methylmalonate-semialdehyde dehydrogenase conserved
PFLU_RS19365 -3.8 -5.3 2-oxo acid dehydrogenase subunit E2 conserved
PFLU_RS26290 -3.8 -0.9 2Fe-2S iron-sulfur cluster binding domain-containing protein compare
PFLU_RS00870 -3.8 -1.6 hypothetical protein compare
PFLU_RS19350 -3.8 -3.7 Lrp/AsnC family transcriptional regulator conserved
PFLU_RS21845 -3.8 -8.5 flagellar basal body P-ring protein FlgI compare
PFLU_RS07225 -3.8 -13.7 L-aspartate oxidase compare
PFLU_RS03970 -3.8 -8.0 carboxylating nicotinate-nucleotide diphosphorylase compare
PFLU_RS19360 -3.7 -6.2 alpha-ketoacid dehydrogenase subunit beta conserved
PFLU_RS20580 -3.7 -5.7 3-isopropylmalate dehydratase large subunit compare
PFLU_RS02590 -3.7 -6.2 ATP phosphoribosyltransferase regulatory subunit compare
PFLU_RS19550 -3.7 -0.9 ABC transporter ATP-binding protein compare
PFLU_RS25640 -3.7 -7.0 ketol-acid reductoisomerase compare
PFLU_RS19355 -3.6 -6.9 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) subunit alpha conserved
PFLU_RS04470 -3.6 -4.9 histidinol dehydrogenase compare
PFLU_RS29880 -3.6 -12.0 acetyl-CoA carboxylase biotin carboxylase subunit compare
PFLU_RS21795 -3.5 -22.3 sigma-54-dependent Fis family transcriptional regulator compare
PFLU_RS01605 -3.5 -5.4 imidazoleglycerol-phosphate dehydratase HisB compare
PFLU_RS27370 -3.5 -9.6 anthranilate phosphoribosyltransferase compare
PFLU_RS27365 -3.5 -7.5 indole-3-glycerol phosphate synthase TrpC compare
PFLU_RS28535 -3.5 -10.5 dihydroxy-acid dehydratase compare
PFLU_RS27360 -3.5 -5.8 lipoate--protein ligase family protein conserved
PFLU_RS22895 -3.4 -16.2 PLP-dependent aminotransferase family protein compare
PFLU_RS01620 -3.4 -3.3 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase compare
PFLU_RS26250 -3.4 -9.3 ferredoxin--NADP reductase compare
PFLU_RS14785 -3.4 -6.1 enoyl-CoA hydratase/isomerase family protein conserved
PFLU_RS27650 -3.4 -12.4 biotin synthase BioB compare
PFLU_RS01900 -3.3 -3.2 phosphoribosyl-AMP cyclohydrolase compare
PFLU_RS22680 -3.3 -5.9 Fe/S-dependent 2-methylisocitrate dehydratase AcnD compare
PFLU_RS24765 -3.2 -18.1 2-isopropylmalate synthase compare
PFLU_RS18950 -3.2 -7.5 MerR family DNA-binding transcriptional regulator compare
PFLU_RS29515 -3.2 -9.7 RidA family protein compare
PFLU_RS22690 -3.2 -6.8 methylisocitrate lyase compare
PFLU_RS01610 -3.2 -7.1 imidazole glycerol phosphate synthase subunit HisH compare
PFLU_RS22990 -3.2 -5.7 ADP-ribosylglycohydrolase compare
PFLU_RS04835 -3.1 -1.1 hypothetical protein compare
PFLU_RS20540 -3.1 -8.3 phosphoribosylanthranilate isomerase compare
PFLU_RS08125 -3.1 -4.0 integration host factor subunit beta compare
PFLU_RS20625 -3.1 -2.9 TetR/AcrR family transcriptional regulator compare
PFLU_RS22675 -3.0 -4.1 2-methylaconitate cis-trans isomerase PrpF compare
PFLU_RS05880 -3.0 -4.9 CinA family protein compare
PFLU_RS29365 -2.9 -12.0 cupin domain-containing protein compare
PFLU_RS22695 -2.9 -8.8 GntR family transcriptional regulator compare
PFLU_RS21755 -2.9 -7.9 flagella biosynthesis chaperone FliJ compare
PFLU_RS03570 -2.8 -1.9 hypothetical protein compare
PFLU_RS07650 -2.8 -8.7 fatty acid oxidation complex subunit alpha FadB compare
PFLU_RS20515 -2.8 -2.7 amidophosphoribosyltransferase compare
PFLU_RS05235 -2.8 -6.4 leucyl aminopeptidase compare
PFLU_RS27805 -2.8 -2.9 sarcosine oxidase subunit gamma family protein compare
PFLU_RS00210 -2.7 -1.6 OsmC family protein compare
PFLU_RS26565 -2.7 -1.1 rRNA maturation RNase YbeY compare
PFLU_RS02275 -2.7 -3.2 pyruvate dehydrogenase (acetyl-transferring), homodimeric type compare
PFLU_RS21860 -2.7 -7.6 flagellar basal body rod protein FlgF compare
PFLU_RS23180 -2.7 -11.0 flagellar basal body rod protein FlgB compare
PFLU_RS18735 -2.6 -1.2 hypothetical protein compare
PFLU_RS00180 -2.6 -5.0 tryptophan synthase subunit beta compare
PFLU_RS02180 -2.6 -0.9 thioredoxin TrxC compare
PFLU_RS22105 -2.6 -1.8 cysteine synthase CysM compare
PFLU_RS21850 -2.6 -11.8 flagellar basal body L-ring protein FlgH compare
PFLU_RS05690 -2.6 -1.7 Grx4 family monothiol glutaredoxin compare
PFLU_RS30345 -2.6 -2.9 DUF2559 family protein compare
PFLU_RS13355 -2.6 -8.2 threonine ammonia-lyase, biosynthetic conserved
PFLU_RS18755 -2.6 -8.5 TetR/AcrR family transcriptional regulator compare
PFLU_RS21835 -2.5 -16.1 flagellar hook-associated protein FlgK compare
PFLU_RS31290 -2.5 -1.6 EamA family transporter compare
PFLU_RS00175 -2.4 -5.4 tryptophan synthase subunit alpha compare
PFLU_RS05875 -2.4 -2.3 lysozyme compare
PFLU_RS31440 -2.4 -1.5 hypothetical protein compare
PFLU_RS02690 -2.4 -1.2 hypothetical protein compare
PFLU_RS21810 -2.4 -16.8 flagellar filament capping protein FliD compare
PFLU_RS21765 -2.4 -8.1 flagellar assembly protein FliH compare
PFLU_RS27690 -2.4 -1.9 response regulator compare
PFLU_RS11505 -2.3 -2.0 ABC transporter substrate-binding protein compare
PFLU_RS21705 -2.3 -7.1 flagellar biosynthesis protein FliQ compare
PFLU_RS01955 -2.3 -3.2 DUF971 domain-containing protein compare
PFLU_RS13010 -2.3 -2.2 Fe-S biogenesis protein NfuA compare
PFLU_RS12975 -2.3 -4.9 DUF934 domain-containing protein compare
PFLU_RS23205 -2.3 -10.4 flagellar protein FlgN compare
PFLU_RS04220 -2.3 -6.1 FadR family transcriptional regulator compare
PFLU_RS21855 -2.3 -7.7 flagellar basal-body rod protein FlgG compare
PFLU_RS21775 -2.3 -10.8 flagellar basal body M-ring protein FliF compare
PFLU_RS23175 -2.2 -7.2 flagellar basal body rod protein FlgC compare
PFLU_RS23590 -2.2 -1.9 gluconokinase compare
PFLU_RS13665 -2.2 -1.0 MarR family transcriptional regulator compare
PFLU_RS21830 -2.2 -15.2 flagellar hook-associated protein 3 compare
PFLU_RS28690 -2.2 -11.5 FAD-binding oxidoreductase compare
PFLU_RS17545 -2.2 -1.3 DUF465 domain-containing protein compare
PFLU_RS26145 -2.2 -1.3 hypothetical protein compare
PFLU_RS21675 -2.2 -13.2 flagellar biosynthesis protein FlhA compare
PFLU_RS31630 -2.2 -2.7 hypothetical protein compare
PFLU_RS11490 -2.2 -3.4 ABC transporter ATP-binding protein compare
PFLU_RS30590 -2.2 -1.0 hypothetical protein compare
PFLU_RS04565 -2.2 -0.7 TMEM165/GDT1 family protein compare
PFLU_RS23195 -2.2 -12.1 flagellar basal body P-ring formation protein FlgA compare
PFLU_RS21660 -2.2 -10.1 RNA polymerase sigma factor FliA compare
PFLU_RS21760 -2.1 -9.9 flagellar protein export ATPase FliI compare
PFLU_RS29255 -2.1 -3.2 iron donor protein CyaY compare
PFLU_RS01625 -2.1 -1.4 imidazole glycerol phosphate synthase subunit HisF compare
PFLU_RS22070 -2.1 -3.2 phosphoribosylglycinamide formyltransferase compare
PFLU_RS28895 -2.1 -1.5 DUF2388 domain-containing protein compare
PFLU_RS21780 -2.1 -4.2 flagellar hook-basal body complex protein FliE compare
PFLU_RS21710 -2.1 -4.4 flagellar type III secretion system pore protein FliP compare
PFLU_RS00070 -2.0 -2.5 tetratricopeptide repeat protein compare
PFLU_RS21840 -2.0 -7.7 flagellar assembly peptidoglycan hydrolase FlgJ compare
PFLU_RS03665 -2.0 -5.0 molybdopterin-synthase adenylyltransferase MoeB compare
PFLU_RS31830 -2.0 -0.9 hypothetical protein compare
PFLU_RS21700 -2.0 -6.3 flagellar type III secretion system protein FliR compare
PFLU_RS23165 -2.0 -12.3 flagellar hook protein FlgE compare
PFLU_RS07150 -2.0 -9.2 tripartite tricarboxylate transporter substrate binding protein compare
PFLU_RS30555 -2.0 -1.3 hypothetical protein compare
PFLU_RS26920 -2.0 -4.1 thioredoxin compare
PFLU_RS21735 -2.0 -9.0 flagellar hook-length control protein FliK compare
PFLU_RS13350 -2.0 -1.2 ParD-like family protein compare
PFLU_RS05210 -1.9 -1.7 HU family DNA-binding protein compare
PFLU_RS09500 -1.9 -1.1 hypothetical protein compare
PFLU_RS01895 -1.9 -5.2 phosphoribosyl-ATP diphosphatase compare
PFLU_RS21820 -1.9 -9.9 flagellin compare
PFLU_RS20970 -1.9 -0.8 phytanoyl-CoA dioxygenase family protein compare
PFLU_RS21445 -1.9 -4.3 RluA family pseudouridine synthase compare
PFLU_RS20260 -1.9 -3.9 terminase compare
PFLU_RS11930 -1.9 -1.7 biopolymer transporter ExbD compare
PFLU_RS12980 -1.8 -7.7 nitrite/sulfite reductase compare
PFLU_RS30400 -1.8 -4.1 NAD synthetase compare
PFLU_RS21725 -1.8 -7.2 flagellar motor switch protein FliM compare
PFLU_RS12220 -1.8 -3.7 AraC family transcriptional regulator compare
PFLU_RS31710 -1.8 -1.8 hypothetical protein compare
PFLU_RS23675 -1.8 -2.0 hypothetical protein compare
PFLU_RS02215 -1.8 -1.7 hypothetical protein compare
PFLU_RS18005 -1.8 -1.7 acyl-CoA/acyl-ACP dehydrogenase compare
PFLU_RS21300 -1.8 -2.7 cysteine hydrolase compare
PFLU_RS21695 -1.8 -3.4 flagellar biosynthesis protein FlhB compare
PFLU_RS21665 -1.8 -2.9 MinD/ParA family protein compare
PFLU_RS21770 -1.8 -7.1 flagellar motor switch protein FliG compare
PFLU_RS05910 -1.8 -1.6 response regulator transcription factor compare
PFLU_RS07235 -1.8 -3.4 sigma factor AlgU negative regulatory protein compare
PFLU_RS17390 -1.7 -2.3 DUF4880 domain-containing protein compare
PFLU_RS01390 -1.7 -5.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
PFLU_RS13895 -1.7 -1.1 helix-turn-helix transcriptional regulator compare
PFLU_RS21670 -1.7 -8.1 flagellar biosynthesis protein FlhF compare
PFLU_RS25715 -1.7 -2.1 RNA polymerase-binding protein DksA compare
PFLU_RS30840 -1.7 -2.7 hypothetical protein compare
PFLU_RS01585 -1.7 -5.1 oxidative damage protection protein compare
PFLU_RS17495 -1.7 -1.4 hypothetical protein compare
PFLU_RS30170 -1.7 -4.4 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG compare
PFLU_RS00535 -1.7 -1.8 DUF1127 domain-containing protein compare
PFLU_RS22735 -1.7 -7.8 bifunctional phosphoserine phosphatase/homoserine phosphotransferase ThrH compare
PFLU_RS23130 -1.7 -4.6 response regulator transcription factor compare
PFLU_RS13915 -1.7 -3.3 hypothetical protein compare
PFLU_RS07655 -1.7 -3.0 acetyl-CoA C-acyltransferase FadA compare
PFLU_RS31185 -1.6 -5.3 hypothetical protein compare
PFLU_RS12260 -1.6 -1.1 hypothetical protein compare
PFLU_RS04455 -1.6 -3.9 BolA family transcriptional regulator compare
PFLU_RS20765 -1.6 -1.7 hypothetical protein compare
PFLU_RS30470 -1.6 -1.6 addiction module antidote protein compare
PFLU_RS00310 -1.6 -0.8 twin transmembrane helix small protein compare
PFLU_RS27645 -1.6 -9.0 8-amino-7-oxononanoate synthase compare
PFLU_RS31755 -1.6 -1.0 hypothetical protein compare
PFLU_RS23680 -1.6 -8.0 long-chain fatty acid--CoA ligase compare
PFLU_RS01615 -1.6 -4.0 DUF2164 domain-containing protein compare
PFLU_RS27445 -1.6 -8.0 phosphotransferase compare
PFLU_RS30660 -1.6 -2.2 histidine phosphatase family protein compare
PFLU_RS25360 -1.6 -5.5 glutamate 5-kinase compare
PFLU_RS27305 -1.5 -5.2 anhydro-N-acetylmuramic acid kinase compare
PFLU_RS25875 -1.5 -2.1 transcription elongation factor GreA compare
PFLU_RS23070 -1.5 -0.7 50S ribosomal protein L32 compare
PFLU_RS03380 -1.5 -4.2 chromosome partitioning protein compare
PFLU_RS25815 -1.5 -1.2 transcription termination/antitermination protein NusA compare
PFLU_RS27815 -1.5 -4.5 sarcosine oxidase subunit delta compare
PFLU_RS04505 -1.5 -2.8 hypothetical protein compare
PFLU_RS15610 -1.5 -2.9 helix-turn-helix transcriptional regulator compare
PFLU_RS26535 -1.5 -5.7 thiamine phosphate synthase compare
PFLU_RS25925 -1.5 -1.5 RnfH family protein compare
PFLU_RS28195 -1.5 -9.5 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
PFLU_RS02455 -1.5 -1.7 3',5'-cyclic-AMP phosphodiesterase compare


Specific Phenotypes

For 47 genes in this experiment

For carbon source L-Valine in Pseudomonas fluorescens SBW25-INTG

For carbon source L-Valine across organisms