Experiment set21IT067 for Pseudomonas fluorescens SBW25-INTG

Compare to:

Citraconic acid 20 mM carbon source

200 most important genes:

  gene name fitness t score description  
PFLU_RS10765 -6.2 -21.3 UvrY/SirA/GacA family response regulator transcription factor compare
PFLU_RS14775 -6.0 -4.1 enoyl-CoA hydratase compare
PFLU_RS18410 -5.6 -11.0 response regulator compare
PFLU_RS28645 -5.4 -16.2 phosphoenolpyruvate--protein phosphotransferase compare
PFLU_RS20575 -5.3 -5.2 3-isopropylmalate dehydratase small subunit compare
PFLU_RS28695 -4.9 -9.4 phosphoglycerate dehydrogenase compare
PFLU_RS29880 -4.8 -17.1 acetyl-CoA carboxylase biotin carboxylase subunit compare
PFLU_RS20565 -4.6 -13.3 3-isopropylmalate dehydrogenase compare
PFLU_RS19015 -4.6 -10.3 anti-sigma factor compare
PFLU_RS29095 -4.6 -29.2 polyphosphate kinase 1 compare
PFLU_RS28535 -4.6 -16.4 dihydroxy-acid dehydratase compare
PFLU_RS06055 -4.5 -3.1 chemotaxis response regulator protein-glutamate methylesterase compare
PFLU_RS28385 -4.5 -15.3 homoserine O-acetyltransferase compare
PFLU_RS29875 -4.4 -20.1 oxaloacetate decarboxylase subunit alpha compare
PFLU_RS20580 -4.4 -12.8 3-isopropylmalate dehydratase large subunit compare
PFLU_RS29780 -4.2 -6.5 acyl-CoA thioesterase compare
PFLU_RS24765 -4.2 -21.9 2-isopropylmalate synthase compare
PFLU_RS01620 -4.2 -8.1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase compare
PFLU_RS14760 -4.2 -5.6 SDR family NAD(P)-dependent oxidoreductase compare
PFLU_RS27370 -4.2 -14.3 anthranilate phosphoribosyltransferase compare
PFLU_RS14765 -4.1 -14.3 acetyl-CoA C-acyltransferase compare
PFLU_RS19355 -4.1 -14.7 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) subunit alpha compare
PFLU_RS04465 -4.1 -10.6 ATP phosphoribosyltransferase compare
PFLU_RS27365 -4.1 -11.4 indole-3-glycerol phosphate synthase TrpC compare
PFLU_RS22835 -4.1 -8.3 amidotransferase compare
PFLU_RS25640 -4.1 -14.2 ketol-acid reductoisomerase compare
PFLU_RS19360 -4.1 -18.0 alpha-ketoacid dehydrogenase subunit beta compare
PFLU_RS29885 -4.1 -15.5 LysR family transcriptional regulator compare
PFLU_RS28390 -4.1 -13.4 methionine biosynthesis protein MetW compare
PFLU_RS09010 -4.1 -10.0 dienelactone hydrolase family protein compare
PFLU_RS19365 -4.0 -12.2 2-oxo acid dehydrogenase subunit E2 compare
PFLU_RS20510 -4.0 -15.3 O-succinylhomoserine sulfhydrylase compare
PFLU_RS14245 -3.9 -12.3 AraC family transcriptional regulator compare
PFLU_RS04470 -3.9 -13.2 histidinol dehydrogenase compare
PFLU_RS19350 -3.9 -8.9 Lrp/AsnC family transcriptional regulator compare
PFLU_RS02490 -3.9 -15.7 phosphoserine phosphatase SerB compare
PFLU_RS01625 -3.8 -2.6 imidazole glycerol phosphate synthase subunit HisF compare
PFLU_RS20290 -3.7 -3.5 integration host factor subunit alpha compare
PFLU_RS22685 -3.7 -14.0 2-methylcitrate synthase compare
PFLU_RS28965 -3.7 -10.9 5-formyltetrahydrofolate cyclo-ligase compare
PFLU_RS25645 -3.7 -2.5 acetolactate synthase small subunit compare
PFLU_RS20540 -3.7 -11.7 phosphoribosylanthranilate isomerase compare
PFLU_RS01605 -3.6 -9.1 imidazoleglycerol-phosphate dehydratase HisB compare
PFLU_RS01610 -3.6 -12.9 imidazole glycerol phosphate synthase subunit HisH compare
PFLU_RS28165 -3.6 -12.3 methylenetetrahydrofolate reductase [NAD(P)H] compare
PFLU_RS07650 -3.6 -16.2 fatty acid oxidation complex subunit alpha FadB compare
PFLU_RS19370 -3.6 -11.5 dihydrolipoyl dehydrogenase compare
PFLU_RS00175 -3.6 -6.4 tryptophan synthase subunit alpha compare
PFLU_RS20515 -3.6 -4.2 amidophosphoribosyltransferase compare
PFLU_RS27650 -3.6 -18.3 biotin synthase BioB compare
PFLU_RS02590 -3.5 -10.4 ATP phosphoribosyltransferase regulatory subunit compare
PFLU_RS00180 -3.5 -8.5 tryptophan synthase subunit beta compare
PFLU_RS01900 -3.5 -8.1 phosphoribosyl-AMP cyclohydrolase compare
PFLU_RS03665 -3.5 -7.0 molybdopterin-synthase adenylyltransferase MoeB compare
PFLU_RS14770 -3.4 -8.5 acyl-CoA dehydrogenase compare
PFLU_RS01895 -3.3 -8.0 phosphoribosyl-ATP diphosphatase compare
PFLU_RS25750 -3.3 -3.8 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PFLU_RS18940 -3.2 -11.0 acyl-CoA dehydrogenase compare
PFLU_RS18505 -3.2 -10.2 uroporphyrinogen-III C-methyltransferase compare
PFLU_RS22070 -3.1 -5.5 phosphoribosylglycinamide formyltransferase compare
PFLU_RS22095 -3.1 -16.4 GTP diphosphokinase compare
PFLU_RS28655 -3.1 -14.6 HAD family hydrolase compare
PFLU_RS25715 -3.1 -7.5 RNA polymerase-binding protein DksA compare
PFLU_RS12980 -3.1 -11.2 nitrite/sulfite reductase compare
PFLU_RS27640 -3.1 -4.1 alpha/beta fold hydrolase compare
PFLU_RS28195 -3.0 -18.0 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
PFLU_RS29480 -3.0 -15.9 exodeoxyribonuclease III compare
PFLU_RS22690 -3.0 -14.3 methylisocitrate lyase compare
PFLU_RS25360 -2.9 -8.6 glutamate 5-kinase compare
PFLU_RS27635 -2.9 -12.7 malonyl-ACP O-methyltransferase BioC compare
PFLU_RS26530 -2.9 -16.3 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
PFLU_RS22680 -2.9 -15.3 Fe/S-dependent 2-methylisocitrate dehydratase AcnD compare
PFLU_RS25735 -2.9 -3.9 sigma-54-dependent Fis family transcriptional regulator compare
PFLU_RS27645 -2.8 -14.5 8-amino-7-oxononanoate synthase compare
PFLU_RS12975 -2.8 -6.0 DUF934 domain-containing protein compare
PFLU_RS27475 -2.8 -4.2 symmetrical bis(5'-nucleosyl)-tetraphosphatase compare
PFLU_RS24825 -2.8 -4.8 Fe-S cluster assembly protein IscX compare
PFLU_RS02430 -2.7 -16.7 phosphomethylpyrimidine synthase ThiC compare
PFLU_RS27630 -2.7 -7.4 dethiobiotin synthase compare
PFLU_RS26535 -2.7 -10.0 thiamine phosphate synthase compare
PFLU_RS18645 -2.7 -1.8 NADH-quinone oxidoreductase subunit NuoH compare
PFLU_RS18670 -2.7 -1.8 NADH-quinone oxidoreductase subunit M compare
PFLU_RS22105 -2.6 -4.5 cysteine synthase CysM compare
PFLU_RS18655 -2.5 -1.7 NADH-quinone oxidoreductase subunit J compare
PFLU_RS19170 -2.5 -3.4 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
PFLU_RS28420 -2.5 -10.6 thiazole synthase compare
PFLU_RS07255 -2.5 -5.1 sulfurtransferase TusA family protein compare
PFLU_RS09055 -2.5 -2.4 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
PFLU_RS15610 -2.4 -5.8 helix-turn-helix transcriptional regulator compare
PFLU_RS01965 -2.4 -2.3 ATP-dependent protease subunit HslV compare
PFLU_RS27440 -2.4 -9.2 nucleotidyltransferase family protein compare
PFLU_RS21965 -2.4 -15.8 transporter compare
PFLU_RS06430 -2.4 -17.2 RNA polymerase sigma factor RpoS compare
PFLU_RS02625 -2.4 -11.8 ribonuclease R compare
PFLU_RS18640 -2.4 -3.8 NADH-quinone oxidoreductase subunit NuoG compare
PFLU_RS18635 -2.3 -2.7 NADH-quinone oxidoreductase subunit NuoF compare
PFLU_RS04715 -2.3 -7.8 D-alanine--D-alanine ligase compare
PFLU_RS08125 -2.3 -4.2 integration host factor subunit beta compare
PFLU_RS28650 -2.3 -7.2 RNA pyrophosphohydrolase compare
PFLU_RS24155 -2.2 -14.8 putative 2-dehydropantoate 2-reductase compare
PFLU_RS18620 -2.2 -3.0 NADH-quinone oxidoreductase subunit B compare
PFLU_RS02205 -2.2 -10.0 potassium/proton antiporter compare
PFLU_RS25940 -2.2 -19.1 FCD domain-containing protein compare
PFLU_RS00210 -2.1 -3.0 OsmC family protein compare
PFLU_RS04385 -2.1 -10.5 RNase adapter RapZ compare
PFLU_RS29890 -2.1 -9.3 transcriptional regulator HexR compare
PFLU_RS18665 -2.1 -2.7 NADH-quinone oxidoreductase subunit L compare
PFLU_RS29755 -2.1 -13.0 phosphate ABC transporter ATP-binding protein compare
PFLU_RS18675 -2.0 -1.9 NADH-quinone oxidoreductase subunit NuoN compare
PFLU_RS23235 -2.0 -3.6 Arc family DNA-binding protein compare
PFLU_RS02365 -2.0 -10.3 glycosyltransferase compare
PFLU_RS25740 -2.0 -3.9 polynucleotide adenylyltransferase PcnB compare
PFLU_RS20730 -2.0 -2.0 hypothetical protein compare
PFLU_RS18625 -2.0 -4.2 NADH-quinone oxidoreductase subunit C/D compare
PFLU_RS25755 -1.9 -2.2 pantoate--beta-alanine ligase compare
PFLU_RS00415 -1.9 -1.8 thiol:disulfide interchange protein DsbA/DsbL compare
PFLU_RS06990 -1.9 -10.2 hydroxymethylglutaryl-CoA lyase compare
PFLU_RS23380 -1.9 -2.5 HAD-IB family hydrolase compare
PFLU_RS23920 -1.9 -2.1 septation protein A compare
PFLU_RS07665 -1.8 -2.4 type I DNA topoisomerase compare
PFLU_RS26735 -1.8 -7.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
PFLU_RS04445 -1.8 -6.4 ABC transporter substrate-binding protein compare
PFLU_RS18615 -1.8 -2.0 NADH-quinone oxidoreductase subunit A compare
PFLU_RS24000 -1.8 -13.7 aminomethyl-transferring glycine dehydrogenase compare
PFLU_RS03075 -1.7 -1.6 translation initiation factor Sui1 compare
PFLU_RS04660 -1.7 -5.8 division/cell wall cluster transcriptional repressor MraZ compare
PFLU_RS17450 -1.7 -7.0 carboxynorspermidine decarboxylase compare
PFLU_RS30165 -1.7 -6.9 ParA family protein compare
PFLU_RS13540 -1.7 -3.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
PFLU_RS04440 -1.7 -8.7 outer membrane lipid asymmetry maintenance protein MlaD compare
PFLU_RS24100 -1.7 -10.4 YebC/PmpR family DNA-binding transcriptional regulator compare
PFLU_RS01645 -1.7 -8.1 S41 family peptidase compare
PFLU_RS07785 -1.6 -9.1 VacJ family lipoprotein compare
PFLU_RS29750 -1.6 -5.6 phosphate signaling complex protein PhoU compare
PFLU_RS28785 -1.6 -7.9 glutamine synthetase compare
PFLU_RS22635 -1.6 -12.0 kinase/pyrophosphorylase compare
PFLU_RS22740 -1.6 -4.6 phosphoadenylyl-sulfate reductase compare
PFLU_RS21530 -1.6 -12.6 transporter substrate-binding domain-containing protein compare
PFLU_RS25710 -1.6 -9.5 pyridoxal phosphate-dependent aminotransferase compare
PFLU_RS29065 -1.6 -1.4 amino acid ABC transporter ATP-binding protein compare
PFLU_RS07695 -1.6 -3.5 beta-N-acetylhexosaminidase compare
PFLU_RS07640 -1.5 -8.8 universal stress protein compare
PFLU_RS27620 -1.5 -12.0 acyl-CoA dehydrogenase compare
PFLU_RS17455 -1.5 -5.6 saccharopine dehydrogenase family protein compare
PFLU_RS21825 -1.5 -10.2 ketoacyl-ACP synthase III compare
PFLU_RS04835 -1.5 -1.7 hypothetical protein compare
PFLU_RS24085 -1.5 -3.0 Holliday junction branch migration DNA helicase RuvB compare
PFLU_RS07690 -1.5 -7.0 helix-turn-helix transcriptional regulator compare
PFLU_RS16925 -1.5 -7.8 TRAP transporter small permease compare
PFLU_RS29255 -1.5 -4.0 iron donor protein CyaY compare
PFLU_RS24170 -1.4 -6.8 Nudix family hydrolase compare
PFLU_RS22645 -1.4 -10.2 EamA family transporter compare
PFLU_RS09005 -1.4 -9.9 molecular chaperone HtpG compare
PFLU_RS25875 -1.4 -3.8 transcription elongation factor GreA compare
PFLU_RS19165 -1.4 -3.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PFLU_RS04325 -1.4 -9.9 ribonuclease G compare
PFLU_RS20660 -1.4 -9.2 aspartate/tyrosine/aromatic aminotransferase compare
PFLU_RS12260 -1.4 -2.3 hypothetical protein compare
PFLU_RS04430 -1.4 -6.0 ATP-binding cassette domain-containing protein compare
PFLU_RS25595 -1.4 -1.3 exodeoxyribonuclease V subunit gamma compare
PFLU_RS01960 -1.4 -1.5 ATP-dependent protease ATPase subunit HslU compare
PFLU_RS25585 -1.3 -0.9 exodeoxyribonuclease V subunit alpha compare
PFLU_RS16920 -1.3 -7.7 TRAP transporter large permease compare
PFLU_RS24095 -1.3 -1.5 crossover junction endodeoxyribonuclease RuvC compare
PFLU_RS29770 -1.3 -8.3 phosphate ABC transporter substrate-binding protein PstS compare
PFLU_RS21495 -1.3 -1.2 TlpA family protein disulfide reductase compare
PFLU_RS31070 -1.3 -4.3 hypothetical protein compare
PFLU_RS03645 -1.3 -6.2 tetratricopeptide repeat protein compare
PFLU_RS00695 -1.3 -1.8 DUF2789 domain-containing protein compare
PFLU_RS02280 -1.3 -7.2 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase compare
PFLU_RS29760 -1.3 -7.6 phosphate ABC transporter permease PstA compare
PFLU_RS29765 -1.2 -9.6 ABC transporter permease subunit compare
PFLU_RS21520 -1.2 -3.9 thioesterase compare
PFLU_RS13035 -1.2 -3.0 cobalamin biosynthesis protein CobW compare
PFLU_RS03770 -1.2 -8.6 sulfate adenylyltransferase subunit CysN compare
PFLU_RS01585 -1.2 -5.2 oxidative damage protection protein compare
PFLU_RS24090 -1.2 -2.2 Holliday junction branch migration protein RuvA compare
PFLU_RS04435 -1.2 -5.0 lipid asymmetry maintenance ABC transporter permease subunit MlaE compare
PFLU_RS24205 -1.2 -2.0 DNA binding protein compare
PFLU_RS02180 -1.2 -1.6 thioredoxin TrxC compare
PFLU_RS09100 -1.2 -4.2 HAMP domain-containing protein compare
PFLU_RS27305 -1.2 -6.5 anhydro-N-acetylmuramic acid kinase compare
PFLU_RS27445 -1.2 -9.4 phosphotransferase compare
PFLU_RS23325 -1.1 -6.6 GlxA family transcriptional regulator compare
PFLU_RS03765 -1.1 -7.3 sulfate adenylyltransferase subunit CysD compare
PFLU_RS31215 -1.1 -2.2 hypothetical protein compare
PFLU_RS19175 -1.1 -4.2 trigger factor compare
PFLU_RS24475 -1.1 -10.0 AmpG family muropeptide MFS transporter compare
PFLU_RS24125 -1.1 -1.7 cold-shock protein compare
PFLU_RS20585 -1.1 -8.1 LysR family transcriptional regulator compare
PFLU_RS22895 -1.1 -9.7 PLP-dependent aminotransferase family protein compare
PFLU_RS14440 -1.1 -1.7 hypothetical protein compare
PFLU_RS05690 -1.1 -1.6 Grx4 family monothiol glutaredoxin compare
PFLU_RS19550 -1.1 -1.3 ABC transporter ATP-binding protein compare
PFLU_RS02775 -1.1 -1.3 urease accessory protein UreF compare
PFLU_RS29505 -1.1 -2.4 DNA-directed RNA polymerase subunit omega compare
PFLU_RS25760 -1.1 -4.3 glucose-6-phosphate isomerase compare
PFLU_RS22075 -1.0 -6.1 DUF3108 domain-containing protein compare
PFLU_RS21315 -1.0 -4.5 GTP cyclohydrolase I FolE compare
PFLU_RS13485 -1.0 -8.0 1,4-alpha-glucan branching protein GlgB compare


Specific Phenotypes

For 24 genes in this experiment

For carbon source Citraconic acid in Pseudomonas fluorescens SBW25-INTG

For carbon source Citraconic acid across organisms