Experiment set1S553 for Escherichia coli Nissle 1917

Compare to:

Bas63

200 most detrimental genes:

  gene name fitness t score description  
ECOLIN_RS10575 +4.4 17.1 hypothetical protein compare
ECOLIN_RS14420 +3.5 2.5 sugar ABC transporter ATP-binding protein compare
ECOLIN_RS23745 +3.4 16.8 phosphonate C-P lyase system protein PhnG compare
ECOLIN_RS13550 +3.4 1.5 fatty acid oxidation complex subunit alpha FadJ compare
ECOLIN_RS03640 +2.6 1.4 exo-alpha-sialidase compare
ECOLIN_RS17460 +2.1 1.4 MurR/RpiR family transcriptional regulator compare
ECOLIN_RS01190 +2.0 1.6 transposase compare
ECOLIN_RS01045 +1.8 1.6 envelope stress response activation lipoprotein NlpE compare
ECOLIN_RS00560 +1.8 1.2 GMP reductase compare
ECOLIN_RS01775 +1.8 1.5 putative lateral flagellar export/assembly protein LafU compare
ECOLIN_RS11755 +1.8 1.2 IS110-like element ISEc20 family transposase compare
ECOLIN_RS23460 +1.7 1.6 sigma-54 dependent transcriptional regulator compare
ECOLIN_RS14015 +1.7 1.2 aldehyde dehydrogenase family protein compare
ECOLIN_RS03530 +1.7 1.9 rhomboid family intramembrane serine protease compare
ECOLIN_RS03280 +1.5 1.5 pyruvate/proton symporter CstA compare
ECOLIN_RS12500 +1.5 0.9 D-alanyl-D-alanine endopeptidase compare
ECOLIN_RS04795 +1.5 1.1 30S ribosomal protein S12 methylthiotransferase accessory factor YcaO compare
ECOLIN_RS33350 +1.3 1.1 hypothetical protein compare
ECOLIN_RS25945 +1.3 10.5 Rop family plasmid primer RNA-binding protein compare
ECOLIN_RS25905 +1.3 3.3 type II toxin-antitoxin system RelE/ParE family toxin compare
ECOLIN_RS06280 +1.3 1.5 23S rRNA pseudouridine(955/2504/2580) synthase RluC compare
ECOLIN_RS00245 +1.2 1.4 MFS transporter compare
ECOLIN_RS17090 +1.1 1.3 type II secretion system protein GspC compare
ECOLIN_RS13375 +1.1 2.0 histidine ABC transporter ATP-binding protein HisP compare
ECOLIN_RS14545 +1.1 1.3 SoxR-reducing system protein RseC compare
ECOLIN_RS06070 +1.1 3.0 cardiolipin synthase ClsC compare
ECOLIN_RS03770 +1.1 2.0 potassium-transporting ATPase subunit KdpA compare
ECOLIN_RS22325 +1.0 0.9 TIM barrel protein compare
ECOLIN_RS25940 +1.0 9.9 hypothetical protein compare
ECOLIN_RS00770 +1.0 1.4 outer membrane usher protein compare
ECOLIN_RS05135 +1.0 3.3 hydrogenase expression/formation protein compare
ECOLIN_RS01035 +1.0 1.3 YaeQ family protein compare
ECOLIN_RS25890 +1.0 7.9 MobC family plasmid mobilization relaxosome protein compare
ECOLIN_RS23715 +1.0 1.3 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase compare
ECOLIN_RS14080 +0.9 1.1 formate-dependent uric acid utilization protein AegA compare
ECOLIN_RS25950 +0.9 1.7 plasmid mobilization protein MobA compare
ECOLIN_RS23195 +0.9 1.4 PTS system mannose/fructose/sorbose family transporter subunit IID compare
ECOLIN_RS04150 +0.9 1.9 excinuclease ABC subunit UvrB compare
ECOLIN_RS04020 +0.9 2.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
ECOLIN_RS03345 +0.9 2.3 citrate/succinate antiporter CitT compare
ECOLIN_RS08170 +0.9 1.7 phosphatase PAP2/dual specificity phosphatase family protein compare
ECOLIN_RS33500 +0.9 7.0 relaxase/mobilization nuclease domain-containing protein compare
ECOLIN_RS19105 +0.9 1.5 type II secretion system protein GspM compare
ECOLIN_RS17380 +0.9 1.6 TRAP transporter substrate-binding protein compare
ECOLIN_RS12165 +0.9 1.3 diguanylate cyclase compare
ECOLIN_RS07375 +0.8 1.7 two-component system response regulator NarL compare
ECOLIN_RS11580 +0.8 1.7 colibactin polyketide synthase ClbC compare
ECOLIN_RS23795 +0.8 1.6 LpxT activity modulator PmrR compare
ECOLIN_RS25885 +0.8 6.7 Kiwa anti-phage protein KwaB-like domain-containing protein compare
ECOLIN_RS00235 +0.8 1.0 FAD-dependent oxidoreductase compare
ECOLIN_RS04945 +0.8 2.1 aliphatic sulfonate ABC transporter permease SsuC compare
ECOLIN_RS06970 +0.8 1.4 prophage tail fiber N-terminal domain-containing protein compare
ECOLIN_RS20760 +0.8 1.1 YicC/YloC family endoribonuclease compare
ECOLIN_RS03245 +0.8 3.0 enterobactin transporter EntS compare
ECOLIN_RS02310 +0.8 1.6 YaiY family protein compare
ECOLIN_RS14330 +0.8 1.5 aminopeptidase PepB compare
ECOLIN_RS11625 +0.8 1.8 adenosylcobinamide-GDP ribazoletransferase compare
ECOLIN_RS33460 +0.8 1.3 alpha/beta hydrolase compare
ECOLIN_RS24100 +0.8 1.0 quaternary ammonium compound efflux SMR transporter SugE compare
ECOLIN_RS14915 +0.7 2.2 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI compare
ECOLIN_RS15785 +0.7 1.4 VasL domain-containing protein compare
ECOLIN_RS06940 +0.7 2.1 phage tail tape measure protein compare
ECOLIN_RS19590 +0.7 2.0 fimbrial protein compare
ECOLIN_RS21875 +0.7 2.3 tyrosine recombinase XerC compare
ECOLIN_RS20675 +0.7 1.2 lipopolysaccharide core heptose(II) kinase RfaY compare
ECOLIN_RS11645 +0.7 1.7 TonB-dependent receptor compare
ECOLIN_RS13710 +0.7 0.8 phosphoenolpyruvate--protein phosphotransferase compare
ECOLIN_RS22430 +0.7 2.1 CopG family transcriptional regulator compare
ECOLIN_RS15530 +0.7 1.7 glucarate dehydratase compare
ECOLIN_RS12955 +0.7 1.7 two-component system sensor histidine kinase RcsC compare
ECOLIN_RS19575 +0.7 1.2 fimbrial protein compare
ECOLIN_RS16755 +0.7 2.3 N-acetylneuraminate lyase compare
ECOLIN_RS33360 +0.7 2.1 class II fructose-bisphosphate aldolase compare
ECOLIN_RS12275 +0.7 0.5 galactitol-1-phosphate 5-dehydrogenase compare
ECOLIN_RS00100 +0.7 1.2 hypothetical protein compare
ECOLIN_RS02750 +0.7 2.4 efflux RND transporter permease AcrB compare
ECOLIN_RS14260 +0.7 2.9 intimin-like inverse autotransporter SinH compare
ECOLIN_RS07970 +0.6 1.2 alpha/beta hydrolase compare
ECOLIN_RS18450 +0.6 1.5 PhoP regulatory network protein YrbL compare
ECOLIN_RS15090 +0.6 2.6 sorbitol-6-phosphate dehydrogenase compare
ECOLIN_RS07640 +0.6 1.5 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
ECOLIN_RS14125 +0.6 1.1 neutral zinc metallopeptidase compare
ECOLIN_RS11555 +0.6 1.3 colibactin non-ribosomal peptide synthetase ClbH compare
ECOLIN_RS01690 +0.6 1.3 type I secretion system permease/ATPase compare
ECOLIN_RS01150 +0.6 1.0 class I SAM-dependent methyltransferase compare
ECOLIN_RS12670 +0.6 1.3 pseudouridine kinase compare
ECOLIN_RS25900 +0.6 5.6 MbeD family mobilization/exclusion protein compare
ECOLIN_RS07910 +0.6 1.5 kojibiose phosphorylase compare
ECOLIN_RS13530 +0.6 1.8 fimbria/pilus periplasmic chaperone compare
ECOLIN_RS10435 +0.6 1.3 DUF1983 domain-containing protein compare
ECOLIN_RS10210 +0.6 1.0 lipid-binding membrane homeostasis protein YebT compare
ECOLIN_RS17580 +0.6 1.0 pilus protein compare
ECOLIN_RS15055 +0.6 0.9 recombination regulator RecX compare
ECOLIN_RS20530 +0.6 1.6 DUF3302 domain-containing protein compare
ECOLIN_RS13100 +0.6 1.1 IclR family transcriptional regulator compare
ECOLIN_RS01885 +0.6 1.1 YkgJ family cysteine cluster protein compare
ECOLIN_RS23170 +0.6 1.2 hypothetical protein compare
ECOLIN_RS02655 +0.6 2.1 long-chain acyl-CoA thioesterase FadM compare
ECOLIN_RS08365 +0.6 1.2 L-asparagine permease compare
ECOLIN_RS25600 +0.6 0.8 K5 polysaccharide biosynthesis glycosyltransferase KfiC compare
ECOLIN_RS15440 +0.6 1.1 electron transfer flavoprotein subunit beta/FixA family protein compare
ECOLIN_RS01890 +0.6 1.5 fimbrial chaperone EcpE compare
ECOLIN_RS24655 +0.6 2.0 arginine deiminase compare
ECOLIN_RS12725 +0.6 1.3 cyclic di-GMP phosphodiesterase compare
ECOLIN_RS02340 +0.6 1.2 diguanylate cyclase AdrA compare
ECOLIN_RS10165 +0.6 1.2 PhoP/PhoQ regulator MgrB compare
ECOLIN_RS30800 +0.6 1.0 protein YpfM compare
ECOLIN_RS24415 +0.6 1.0 acyl CoA:acetate/3-ketoacid CoA transferase compare
ECOLIN_RS16005 +0.6 1.9 diaminopropionate ammonia-lyase compare
ECOLIN_RS07785 +0.6 1.3 efflux RND transporter periplasmic adaptor subunit compare
ECOLIN_RS32430 +0.6 4.6 hypothetical protein compare
ECOLIN_RS07985 +0.5 1.8 murein tripeptide ABC transporter substrate-binding protein MppA compare
ECOLIN_RS16985 +0.5 1.7 DUF6088 family protein compare
ECOLIN_RS15190 +0.5 0.7 formate hydrogenlyase assembly protein HycH compare
ECOLIN_RS01465 +0.5 1.2 ETEC_3214 family protein compare
ECOLIN_RS02930 +0.5 2.6 putative ABC transporter permease subunit YbbP compare
ECOLIN_RS04600 +0.5 0.9 arginine ABC transporter ATP-binding protein ArtP compare
ECOLIN_RS13655 +0.5 1.1 oxalyl-CoA decarboxylase compare
ECOLIN_RS17515 +0.5 1.0 outer membrane channel protein TolC compare
ECOLIN_RS21005 +0.5 1.8 hypothetical protein compare
ECOLIN_RS12610 +0.5 1.4 S-formylglutathione hydrolase compare
ECOLIN_RS09535 +0.5 1.0 protein adenylyltransferase SelO compare
ECOLIN_RS14935 +0.5 2.9 glycine betaine/L-proline ABC transporter permease ProW conserved
ECOLIN_RS13945 +0.5 1.7 RpoE-regulated lipoprotein compare
ECOLIN_RS10120 +0.5 0.8 PTS mannose transporter subunit IID compare
ECOLIN_RS05815 +0.5 1.4 DUF4198 domain-containing protein compare
ECOLIN_RS20670 +0.5 0.9 UDP-galactose--(galactosyl) LPS alpha1,2-galactosyltransferase compare
ECOLIN_RS03605 +0.5 1.7 ribonucleotide monophosphatase NagD compare
ECOLIN_RS14205 +0.5 1.6 exopolyphosphatase compare
ECOLIN_RS13870 +0.5 1.8 cysteine synthase A compare
ECOLIN_RS04235 +0.5 0.9 secretion protein HlyD compare
ECOLIN_RS09670 +0.5 1.4 6-phospho-beta-glucosidase compare
ECOLIN_RS24905 +0.5 1.3 DUF3343 domain-containing protein compare
ECOLIN_RS16620 +0.5 0.9 hypothetical protein compare
ECOLIN_RS01210 +0.5 1.8 IS110-like element ISEc45 family transposase compare
ECOLIN_RS18355 +0.5 1.3 DNA-binding transcriptional regulator SfsB compare
ECOLIN_RS05100 +0.5 1.7 FtsH protease modulator YccA compare
ECOLIN_RS20340 +0.5 1.6 HTH-type transcriptional regulator compare
ECOLIN_RS05080 +0.5 2.2 heat shock protein HspQ compare
ECOLIN_RS04975 +0.5 0.9 6-N-hydroxylaminopurine resistance protein YcbX compare
ECOLIN_RS12000 +0.5 1.1 mannose-1-phosphate guanyltransferase compare
ECOLIN_RS17160 +0.5 0.9 NAD-dependent epimerase/dehydratase family protein compare
ECOLIN_RS04560 +0.5 0.9 putrescine ABC transporter permease PotH compare
ECOLIN_RS18275 +0.5 1.8 argininosuccinate synthase compare
ECOLIN_RS02425 +0.5 0.9 proline-specific permease ProY compare
ECOLIN_RS14140 +0.5 1.4 outer membrane protein assembly factor BamC conserved
ECOLIN_RS22845 +0.5 0.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
ECOLIN_RS04395 +0.5 1.6 molybdopterin-synthase adenylyltransferase MoeB compare
ECOLIN_RS11570 +0.5 0.8 colibactin biosynthesis aminomalonyl-acyl carrier protein ClbE compare
ECOLIN_RS02005 +0.5 1.2 LutB/LldF family L-lactate oxidation iron-sulfur protein compare
ECOLIN_RS22045 +0.5 2.0 DUF1116 domain-containing protein compare
ECOLIN_RS12210 +0.5 1.0 MFS transporter compare
ECOLIN_RS20795 +0.5 1.3 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
ECOLIN_RS04810 +0.5 0.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
ECOLIN_RS16770 +0.5 0.9 transposase compare
ECOLIN_RS16290 +0.5 1.0 sulfate/molybdate ABC transporter ATP-binding protein compare
ECOLIN_RS03120 +0.5 1.2 Cu(+)/Ag(+) sensor histidine kinase CusS compare
ECOLIN_RS03010 +0.5 1.3 DUF1116 domain-containing protein compare
ECOLIN_RS13730 +0.5 1.3 PTS fructose transporter subunit IIB compare
ECOLIN_RS09250 +0.5 1.0 DNA-binding transcriptional activator PunR compare
ECOLIN_RS18170 +0.5 2.9 lipoprotein NlpI compare
ECOLIN_RS16380 +0.5 1.6 SprT family zinc-dependent metalloprotease compare
ECOLIN_RS15085 +0.5 1.0 PTS glucitol/sorbitol transporter subunit IIA compare
ECOLIN_RS05120 +0.5 1.3 Ni/Fe-hydrogenase b-type cytochrome subunit compare
ECOLIN_RS04115 +0.5 0.8 kinase inhibitor compare
ECOLIN_RS07460 +0.4 1.9 formyltetrahydrofolate deformylase compare
ECOLIN_RS33385 +0.4 1.3 DUF6404 family protein compare
ECOLIN_RS05075 +0.4 0.9 CoA-binding protein compare
ECOLIN_RS00030 +0.4 1.4 DUF2502 domain-containing protein compare
ECOLIN_RS05190 +0.4 0.8 TMAO reductase system periplasmic protein TorT compare
ECOLIN_RS25675 +0.4 1.3 Ag43/Cah family autotransporter adhesin compare
ECOLIN_RS24955 +0.4 1.1 restriction endonuclease subunit S compare
ECOLIN_RS15970 +0.4 1.5 tRNA-Gly compare
ECOLIN_RS04055 +0.4 1.3 molybdenum-dependent transcriptional regulator compare
ECOLIN_RS20090 +0.4 0.6 acid resistance transcriptional activator GadE compare
ECOLIN_RS00375 +0.4 1.6 DNA-binding transcriptional regulator SgrR compare
ECOLIN_RS17920 +0.4 1.2 enamine/imine deaminase compare
ECOLIN_RS08690 +0.4 1.1 tagaturonate reductase compare
ECOLIN_RS24295 +0.4 0.9 DUF1190 domain-containing protein compare
ECOLIN_RS15100 +0.4 1.8 glucitol operon DNA-binding transcriptional repressor SrlR compare
ECOLIN_RS07975 +0.4 0.9 DNA-binding transcriptional regulator PgrR compare
ECOLIN_RS32100 +0.4 1.8 IS110 family transposase compare
ECOLIN_RS24635 +0.4 2.2 arginine repressor compare
ECOLIN_RS15645 +0.4 1.2 DUF423 domain-containing protein compare
ECOLIN_RS02735 +0.4 0.9 maltose O-acetyltransferase compare
ECOLIN_RS03825 +0.4 1.5 AbrB family transcriptional regulator compare
ECOLIN_RS06990 +0.4 1.7 iron/manganese ABC transporter permease subunit SitC compare
ECOLIN_RS14465 +0.4 1.4 two component system sensor histidine kinase QseE/GlrK compare
ECOLIN_RS18390 +0.4 1.8 phospholipid ABC transporter ATP-binding protein MlaF compare
ECOLIN_RS15330 +0.4 1.3 RNA polymerase sigma factor RpoS compare
ECOLIN_RS01850 +0.4 1.9 vacuolating autotransporter toxin Vat compare
ECOLIN_RS10920 +0.4 1.0 L-cystine ABC transporter ATP-binding protein TcyN compare
ECOLIN_RS13825 +0.4 1.2 xanthosine/proton symporter XapB compare
ECOLIN_RS24025 +0.4 1.9 transcriptional regulator compare
ECOLIN_RS13465 +0.4 1.0 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC compare
ECOLIN_RS24255 +0.4 1.2 adenylosuccinate synthase compare
ECOLIN_RS17290 +0.4 0.9 TIGR00645 family protein compare
ECOLIN_RS15575 +0.4 1.4 SecY-interacting protein compare
ECOLIN_RS19905 +0.4 1.1 PTS sugar transporter subunit IIA compare
ECOLIN_RS11135 +0.4 1.0 DUF808 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Escherichia coli Nissle 1917 in phage experiments

For phage MOI 10 across organisms