Experiment set1S482 for Escherichia coli Nissle 1917

Compare to:

Bas22

200 most detrimental genes:

  gene name fitness t score description  
ECOLIN_RS14420 +3.0 2.3 sugar ABC transporter ATP-binding protein compare
ECOLIN_RS13550 +2.9 1.6 fatty acid oxidation complex subunit alpha FadJ compare
ECOLIN_RS10575 +2.5 7.8 hypothetical protein compare
ECOLIN_RS23745 +2.3 9.1 phosphonate C-P lyase system protein PhnG compare
ECOLIN_RS11755 +2.1 1.4 IS110-like element ISEc20 family transposase compare
ECOLIN_RS25945 +2.0 17.9 Rop family plasmid primer RNA-binding protein compare
ECOLIN_RS12500 +1.9 1.0 D-alanyl-D-alanine endopeptidase compare
ECOLIN_RS25940 +1.8 17.2 hypothetical protein compare
ECOLIN_RS22640 +1.7 3.9 ATP-dependent protease subunit HslV compare
ECOLIN_RS14015 +1.6 1.6 aldehyde dehydrogenase family protein compare
ECOLIN_RS17460 +1.6 1.2 MurR/RpiR family transcriptional regulator compare
ECOLIN_RS00560 +1.6 1.1 GMP reductase compare
ECOLIN_RS25950 +1.6 5.3 plasmid mobilization protein MobA compare
ECOLIN_RS25890 +1.6 11.3 MobC family plasmid mobilization relaxosome protein compare
ECOLIN_RS33500 +1.5 13.3 relaxase/mobilization nuclease domain-containing protein compare
ECOLIN_RS01045 +1.4 1.3 envelope stress response activation lipoprotein NlpE compare
ECOLIN_RS04795 +1.3 1.2 30S ribosomal protein S12 methylthiotransferase accessory factor YcaO compare
ECOLIN_RS20655 +1.3 5.5 lipopolysaccharide heptosyltransferase RfaC compare
ECOLIN_RS32430 +1.3 6.8 hypothetical protein compare
ECOLIN_RS17385 +1.2 1.9 TRAP transporter small permease compare
ECOLIN_RS01775 +1.2 1.4 putative lateral flagellar export/assembly protein LafU compare
ECOLIN_RS02760 +1.2 2.7 multidrug efflux transporter transcriptional repressor AcrR compare
ECOLIN_RS12540 +1.2 2.2 CidB/LrgB family autolysis modulator compare
ECOLIN_RS03280 +1.1 1.0 pyruvate/proton symporter CstA compare
ECOLIN_RS02885 +1.1 1.7 hypothetical protein compare
ECOLIN_RS00770 +1.1 1.8 outer membrane usher protein compare
ECOLIN_RS05190 +1.1 2.0 TMAO reductase system periplasmic protein TorT compare
ECOLIN_RS25905 +1.1 5.6 type II toxin-antitoxin system RelE/ParE family toxin compare
ECOLIN_RS14550 +1.1 3.1 sigma-E factor regulatory protein RseB compare
ECOLIN_RS23460 +1.1 1.2 sigma-54 dependent transcriptional regulator compare
ECOLIN_RS01035 +1.0 1.4 YaeQ family protein compare
ECOLIN_RS18440 +1.0 5.4 RNase adapter RapZ compare
ECOLIN_RS01190 +1.0 0.9 transposase compare
ECOLIN_RS20650 +1.0 2.8 ADP-heptose--LPS heptosyltransferase RfaF compare
ECOLIN_RS25900 +1.0 8.6 MbeD family mobilization/exclusion protein compare
ECOLIN_RS03990 +1.0 2.0 quinolinate synthase NadA compare
ECOLIN_RS05325 +0.9 2.9 poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD compare
ECOLIN_RS09780 +0.9 1.5 ABC transporter permease compare
ECOLIN_RS27745 +0.9 1.9 GlxA family transcriptional regulator compare
ECOLIN_RS14200 +0.9 2.5 polyphosphate kinase 1 compare
ECOLIN_RS14780 +0.9 5.6 outer membrane protein assembly factor BamE compare
ECOLIN_RS14230 +0.9 1.4 DUF5384 family protein compare
ECOLIN_RS23305 +0.9 7.4 maltoporin LamB conserved
ECOLIN_RS09665 +0.9 1.6 chitin disaccharide deacetylase compare
ECOLIN_RS20645 +0.9 2.7 ADP-glyceromanno-heptose 6-epimerase compare
ECOLIN_RS25885 +0.9 8.3 Kiwa anti-phage protein KwaB-like domain-containing protein compare
ECOLIN_RS33350 +0.9 1.3 hypothetical protein compare
ECOLIN_RS17615 +0.9 1.9 bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE compare
ECOLIN_RS04975 +0.9 1.6 6-N-hydroxylaminopurine resistance protein YcbX compare
ECOLIN_RS17090 +0.9 0.9 type II secretion system protein GspC compare
ECOLIN_RS14080 +0.9 1.4 formate-dependent uric acid utilization protein AegA compare
ECOLIN_RS24560 +0.9 6.2 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
ECOLIN_RS01155 +0.8 3.7 murein transglycosylase D compare
ECOLIN_RS07195 +0.8 1.6 potassium/proton antiporter compare
ECOLIN_RS06900 +0.8 1.4 minor capsid protein E compare
ECOLIN_RS00590 +0.8 3.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD compare
ECOLIN_RS04150 +0.8 1.7 excinuclease ABC subunit UvrB compare
ECOLIN_RS15650 +0.8 1.8 glycine cleavage system transcriptional regulator GcvA compare
ECOLIN_RS33080 +0.8 2.0 protein YsdE compare
ECOLIN_RS16460 +0.8 1.5 YggL family protein compare
ECOLIN_RS16825 +0.8 1.0 YfjI family protein compare
ECOLIN_RS11580 +0.8 1.5 colibactin polyketide synthase ClbC compare
ECOLIN_RS22325 +0.8 1.4 TIM barrel protein compare
ECOLIN_RS23075 +0.8 2.4 DUF1481 domain-containing protein compare
ECOLIN_RS19520 +0.8 5.5 HTH-type transcriptional regulator MalT conserved
ECOLIN_RS11400 +0.8 1.2 yersiniabactin polyketide synthase HMWP1 compare
ECOLIN_RS04110 +0.8 3.6 putative acyl-CoA thioester hydrolase compare
ECOLIN_RS06965 +0.8 1.7 host specificity protein J compare
ECOLIN_RS07250 +0.8 1.7 alpha,alpha-trehalase compare
ECOLIN_RS04985 +0.8 1.8 ABC transporter ATP-binding protein compare
ECOLIN_RS24600 +0.8 3.1 PTS trehalose transporter subunit IIBC compare
ECOLIN_RS23300 +0.8 4.7 maltose/maltodextrin ABC transporter ATP-binding protein MalK compare
ECOLIN_RS15165 +0.7 2.1 DUF4259 domain-containing protein compare
ECOLIN_RS07375 +0.7 1.3 two-component system response regulator NarL compare
ECOLIN_RS01095 +0.7 2.3 methionine ABC transporter ATP-binding protein MetN compare
ECOLIN_RS09250 +0.7 1.6 DNA-binding transcriptional activator PunR compare
ECOLIN_RS22040 +0.7 2.6 carbamate kinase compare
ECOLIN_RS12100 +0.7 1.3 colanic acid biosynthesis acetyltransferase WcaF compare
ECOLIN_RS00080 +0.7 3.0 molecular chaperone DnaJ compare
ECOLIN_RS07975 +0.7 1.1 DNA-binding transcriptional regulator PgrR compare
ECOLIN_RS02765 +0.7 2.5 mechanosensitive channel MscK compare
ECOLIN_RS04560 +0.7 1.3 putrescine ABC transporter permease PotH compare
ECOLIN_RS09685 +0.7 1.7 PTS N,N'-diacetylchitobiose transporter subunit IIC compare
ECOLIN_RS16720 +0.7 1.9 transcriptional regulator NanR compare
ECOLIN_RS19850 +0.7 2.5 phage sensitivity protein DcrB compare
ECOLIN_RS09260 +0.7 1.6 cyclopropane fatty acyl phospholipid synthase compare
ECOLIN_RS12165 +0.7 2.2 diguanylate cyclase compare
ECOLIN_RS06335 +0.7 2.3 cell division protein YceG compare
ECOLIN_RS01755 +0.7 1.3 class II glutamine amidotransferase compare
ECOLIN_RS22635 +0.7 2.0 HslU--HslV peptidase ATPase subunit compare
ECOLIN_RS13920 +0.7 2.2 thiosulfate/sulfate ABC transporter substrate-binding protein CysP compare
ECOLIN_RS13610 +0.7 1.0 DNA-binding transcriptional regulator DsdC compare
ECOLIN_RS18600 +0.7 4.1 AsmA2 domain-containing protein YhdP compare
ECOLIN_RS06235 +0.7 1.4 flagellar basal-body rod protein FlgF compare
ECOLIN_RS11970 +0.7 1.4 imidazole glycerol phosphate synthase subunit HisF compare
ECOLIN_RS16080 +0.7 1.9 formate-dependent uric acid utilization protein YgfT compare
ECOLIN_RS31295 +0.7 1.0 galactarate dehydratase compare
ECOLIN_RS13945 +0.7 1.6 RpoE-regulated lipoprotein compare
ECOLIN_RS15245 +0.7 1.6 hydrogenase 3 maturation protein HypC compare
ECOLIN_RS17380 +0.7 0.9 TRAP transporter substrate-binding protein compare
ECOLIN_RS02750 +0.7 1.4 efflux RND transporter permease AcrB compare
ECOLIN_RS06605 +0.7 1.9 two-component system sensor histidine kinase PhoQ compare
ECOLIN_RS14010 +0.7 2.1 ethanolamine utilization protein EutJ compare
ECOLIN_RS27255 +0.7 1.6 IS66 family transposase compare
ECOLIN_RS00245 +0.7 1.1 MFS transporter compare
ECOLIN_RS04405 +0.7 0.9 beta-aspartyl-peptidase compare
ECOLIN_RS10420 +0.7 1.3 tail fiber assembly protein compare
ECOLIN_RS11570 +0.6 1.0 colibactin biosynthesis aminomalonyl-acyl carrier protein ClbE compare
ECOLIN_RS11380 +0.6 2.2 yersiniabactin ABC transporter ATP-binding/permease protein YbtP compare
ECOLIN_RS02305 +0.6 1.7 surface-exposed outer membrane lipoprotein YaiW compare
ECOLIN_RS18390 +0.6 3.0 phospholipid ABC transporter ATP-binding protein MlaF compare
ECOLIN_RS01975 +0.6 1.2 aldo/keto reductase compare
ECOLIN_RS22140 +0.6 4.2 Sec-independent protein translocase subunit TatC compare
ECOLIN_RS20310 +0.6 1.7 DNA-3-methyladenine glycosylase I compare
ECOLIN_RS19395 +0.6 5.4 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA compare
ECOLIN_RS02655 +0.6 1.8 long-chain acyl-CoA thioesterase FadM compare
ECOLIN_RS08250 +0.6 1.6 YdcK family protein compare
ECOLIN_RS30030 +0.6 1.0 transposase compare
ECOLIN_RS23310 +0.6 3.8 maltose operon protein MalM compare
ECOLIN_RS06280 +0.6 0.7 23S rRNA pseudouridine(955/2504/2580) synthase RluC compare
ECOLIN_RS05025 +0.6 3.4 porin OmpA compare
ECOLIN_RS02155 +0.6 1.8 2-methylcitrate synthase compare
ECOLIN_RS12515 +0.6 1.0 SDR family oxidoreductase compare
ECOLIN_RS16295 +0.6 1.3 nucleoside/nucleotide kinase family protein compare
ECOLIN_RS10825 +0.6 1.2 arabinose ABC transporter ATP-binding protein AraG compare
ECOLIN_RS01995 +0.6 1.4 reactive chlorine-specific transcriptional regulator RclR compare
ECOLIN_RS24905 +0.6 1.4 DUF3343 domain-containing protein compare
ECOLIN_RS03605 +0.6 1.4 ribonucleotide monophosphatase NagD compare
ECOLIN_RS23405 +0.6 1.2 alanine racemase compare
ECOLIN_RS00100 +0.6 1.2 hypothetical protein compare
ECOLIN_RS30470 +0.6 1.1 IS3 family transposase compare
ECOLIN_RS00790 +0.6 3.4 polynucleotide adenylyltransferase PcnB compare
ECOLIN_RS00235 +0.6 0.9 FAD-dependent oxidoreductase compare
ECOLIN_RS04360 +0.6 1.9 anion transporter compare
ECOLIN_RS24295 +0.6 2.0 DUF1190 domain-containing protein compare
ECOLIN_RS23715 +0.6 0.9 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase compare
ECOLIN_RS11140 +0.6 0.9 drug/metabolite exporter YedA compare
ECOLIN_RS03530 +0.6 1.3 rhomboid family intramembrane serine protease compare
ECOLIN_RS18380 +0.6 2.7 outer membrane lipid asymmetry maintenance protein MlaD compare
ECOLIN_RS04415 +0.6 0.7 glutathione ABC transporter substrate-binding protein GsiB compare
ECOLIN_RS20545 +0.6 1.8 mannitol operon repressor MtlR compare
ECOLIN_RS06405 +0.6 1.1 glycine zipper 2TM domain-containing protein compare
ECOLIN_RS20415 +0.6 3.6 protein bax compare
ECOLIN_RS18100 +0.6 2.9 DnaA initiator-associating protein DiaA compare
ECOLIN_RS05865 +0.6 1.3 hypothetical protein compare
ECOLIN_RS14545 +0.6 0.6 SoxR-reducing system protein RseC compare
ECOLIN_RS29300 +0.6 0.7 hypothetical protein compare
ECOLIN_RS15670 +0.6 1.9 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA compare
ECOLIN_RS16770 +0.6 0.9 transposase compare
ECOLIN_RS01910 +0.6 1.1 common pilus major fimbrillin subunit EcpA compare
ECOLIN_RS31675 +0.5 1.0 hypothetical protein compare
ECOLIN_RS18090 +0.5 3.0 penicillin-binding protein activator LpoA compare
ECOLIN_RS07755 +0.5 1.1 cyclic di-GMP phosphodiesterase compare
ECOLIN_RS14180 +0.5 1.0 uracil permease compare
ECOLIN_RS16070 +0.5 2.0 guanine/hypoxanthine transporter GhxQ compare
ECOLIN_RS14240 +0.5 2.8 IMP dehydrogenase compare
ECOLIN_RS04835 +0.5 2.0 ComEC family protein compare
ECOLIN_RS05225 +0.5 1.0 bifunctional glucose-1-phosphatase/inositol phosphatase compare
ECOLIN_RS32100 +0.5 1.4 IS110 family transposase compare
ECOLIN_RS08555 +0.5 1.5 glycoside hydrolase family 10 protein compare
ECOLIN_RS25100 +0.5 1.2 ribosomal protein S18-alanine N-acetyltransferase compare
ECOLIN_RS20760 +0.5 0.8 YicC/YloC family endoribonuclease compare
ECOLIN_RS03340 +0.5 1.1 ribonuclease I compare
ECOLIN_RS15195 +0.5 1.1 formate hydrogenlyase subunit HycG compare
ECOLIN_RS15805 +0.5 0.9 PTS transporter subunit EIIC compare
ECOLIN_RS15915 +0.5 2.1 lysophospholipid transporter LplT compare
ECOLIN_RS09195 +0.5 1.2 DNA-binding transcriptional regulator NemR compare
ECOLIN_RS12305 +0.5 0.8 class I fructose-bisphosphate aldolase compare
ECOLIN_RS01685 +0.5 2.0 TolC family protein compare
ECOLIN_RS18385 +0.5 3.8 lipid asymmetry maintenance ABC transporter permease subunit MlaE compare
ECOLIN_RS06690 +0.5 1.4 hypothetical protein compare
ECOLIN_RS16300 +0.5 1.8 fumarase E compare
ECOLIN_RS19575 +0.5 1.4 fimbrial protein compare
ECOLIN_RS14125 +0.5 0.8 neutral zinc metallopeptidase compare
ECOLIN_RS08200 +0.5 1.1 cytochrome b561 compare
ECOLIN_RS18570 +0.5 1.4 barstar family protein compare
ECOLIN_RS21860 +0.5 1.4 lipoprotein compare
ECOLIN_RS12935 +0.5 2.3 porin OmpC compare
ECOLIN_RS02205 +0.5 2.1 S-formylglutathione hydrolase compare
ECOLIN_RS33360 +0.5 1.4 class II fructose-bisphosphate aldolase compare
ECOLIN_RS01885 +0.5 0.8 YkgJ family cysteine cluster protein compare
ECOLIN_RS22815 +0.5 1.9 [formate-C-acetyltransferase]-activating enzyme compare
ECOLIN_RS10080 +0.5 0.8 aminodeoxychorismate synthase component 1 compare
ECOLIN_RS15555 +0.5 1.4 YqcC family protein compare
ECOLIN_RS13910 +0.5 1.5 sulfate/thiosulfate ABC transporter permease CysW compare
ECOLIN_RS01800 +0.5 2.0 cytosol nonspecific dipeptidase compare
ECOLIN_RS23565 +0.5 0.9 cytochrome c nitrite reductase Fe-S protein compare
ECOLIN_RS15875 +0.5 3.4 phosphoenolpyruvate--protein phosphotransferase compare
ECOLIN_RS09730 +0.5 0.8 N-succinylarginine dihydrolase compare
ECOLIN_RS14855 +0.5 1.2 DNA-binding transcriptional regulator CsiR compare
ECOLIN_RS02175 +0.5 0.9 cytosine/isoguanine deaminase compare
ECOLIN_RS00435 +0.5 1.2 division/cell wall cluster transcriptional repressor MraZ compare
ECOLIN_RS30365 +0.5 0.9 protein YkgL compare
ECOLIN_RS27985 +0.5 0.8 IS21 family transposase compare
ECOLIN_RS16115 +0.5 2.7 single-stranded-DNA-specific exonuclease RecJ compare
ECOLIN_RS02080 +0.5 0.8 LysR substrate-binding domain-containing protein compare
ECOLIN_RS33385 +0.5 1.2 DUF6404 family protein compare
ECOLIN_RS09535 +0.5 0.8 protein adenylyltransferase SelO compare
ECOLIN_RS15785 +0.5 1.9 VasL domain-containing protein compare
ECOLIN_RS04600 +0.5 0.7 arginine ABC transporter ATP-binding protein ArtP compare


Specific Phenotypes

None in this experiment

For Escherichia coli Nissle 1917 in phage experiments

For phage MOI 10 across organisms