Experiment set1S423 for Parabacteroides merdae CL09T00C40

Compare to:

Beta-Lactose 10 mg/mL carbon source

200 most important genes:

  gene name fitness t score description  
HMPREF1078_RS16675 -7.1 -8.5 ketol-acid reductoisomerase compare
HMPREF1078_RS15405 -6.8 -4.7 NAD(P)-dependent oxidoreductase compare
HMPREF1078_RS16640 -6.8 -11.3 3-isopropylmalate dehydrogenase compare
HMPREF1078_RS15400 -6.7 -12.1 3-phosphoserine/phosphohydroxythreonine transaminase compare
HMPREF1078_RS05935 -6.5 -4.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
HMPREF1078_RS10660 -6.5 -10.8 acetylornithine carbamoyltransferase compare
HMPREF1078_RS10390 -6.4 -7.6 cofactor-independent phosphoglycerate mutase compare
HMPREF1078_RS10570 -6.2 -8.5 GNAT family N-acetyltransferase compare
HMPREF1078_RS02455 -6.2 -4.3 ATP phosphoribosyltransferase compare
HMPREF1078_RS10385 -6.2 -10.4 bifunctional aspartate kinase/homoserine dehydrogenase I compare
HMPREF1078_RS01135 -6.1 -10.2 prephenate dehydratase compare
HMPREF1078_RS16655 -6.1 -4.2 3-isopropylmalate dehydratase small subunit compare
HMPREF1078_RS13560 -6.0 -5.9 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
HMPREF1078_RS10650 -6.0 -8.2 glutamate 5-kinase compare
HMPREF1078_RS10395 -6.0 -12.1 threonine synthase compare
HMPREF1078_RS01120 -6.0 -14.4 prephenate dehydrogenase/arogenate dehydrogenase family protein compare
HMPREF1078_RS01130 -5.9 -14.9 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme compare
HMPREF1078_RS10575 -5.9 -11.4 argininosuccinate synthase compare
HMPREF1078_RS00135 -5.9 -9.8 anthranilate phosphoribosyltransferase compare
HMPREF1078_RS04700 -5.9 -7.0 type II 3-dehydroquinate dehydratase compare
HMPREF1078_RS13545 -5.9 -12.6 diaminopimelate decarboxylase compare
HMPREF1078_RS02440 -5.8 -7.0 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB compare
HMPREF1078_RS14660 -5.8 -15.1 glycosyltransferase compare
HMPREF1078_RS12535 -5.8 -4.0 anaerobic ribonucleoside-triphosphate reductase activating protein compare
HMPREF1078_RS10580 -5.8 -12.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
HMPREF1078_RS02450 -5.7 -11.0 histidinol dehydrogenase compare
HMPREF1078_RS00150 -5.7 -14.3 tryptophan synthase subunit beta compare
HMPREF1078_RS04325 -5.7 -22.3 phosphoribosylformylglycinamidine synthase compare
HMPREF1078_RS00130 -5.7 -6.7 indole-3-glycerol phosphate synthase TrpC compare
HMPREF1078_RS13575 -5.6 -14.9 imidazole glycerol phosphate synthase subunit HisH compare
HMPREF1078_RS16660 -5.6 -14.5 3-isopropylmalate dehydratase large subunit compare
HMPREF1078_RS10655 -5.6 -10.0 glutamate-5-semialdehyde dehydrogenase compare
HMPREF1078_RS15335 -5.6 -7.6 acetylglutamate kinase compare
HMPREF1078_RS01125 -5.5 -12.9 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase type II compare
HMPREF1078_RS11315 -5.5 -18.1 argininosuccinate lyase compare
HMPREF1078_RS14700 -5.5 -19.2 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD compare
HMPREF1078_RS16690 -5.5 -12.3 biosynthetic-type acetolactate synthase large subunit compare
HMPREF1078_RS13565 -5.5 -11.7 imidazole glycerol phosphate synthase subunit HisF compare
HMPREF1078_RS14200 -5.5 -3.8 shikimate dehydrogenase compare
HMPREF1078_RS16695 -5.4 -11.6 dihydroxy-acid dehydratase compare
HMPREF1078_RS10620 -5.4 -10.3 pyrroline-5-carboxylate reductase compare
HMPREF1078_RS12080 -5.3 -16.0 pyridoxal phosphate-dependent aminotransferase compare
HMPREF1078_RS02445 -5.2 -8.0 histidinol-phosphate transaminase compare
HMPREF1078_RS13570 -5.2 -14.2 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase compare
HMPREF1078_RS12530 -5.1 -10.4 anaerobic ribonucleoside triphosphate reductase compare
HMPREF1078_RS10585 -5.1 -14.2 aspartate aminotransferase family protein compare
HMPREF1078_RS07205 -5.0 -6.0 shikimate kinase compare
HMPREF1078_RS00120 -5.0 -14.0 tryptophan synthase subunit alpha compare
HMPREF1078_RS05545 -4.9 -10.4 4-hydroxy-tetrahydrodipicolinate reductase compare
HMPREF1078_RS06805 -4.9 -15.6 phosphoribosylamine--glycine ligase compare
HMPREF1078_RS10645 -4.9 -12.4 AMP-binding protein compare
HMPREF1078_RS00145 -4.9 -17.1 anthranilate synthase component I family protein compare
HMPREF1078_RS07755 -4.9 -7.3 outer membrane protein assembly factor BamD compare
HMPREF1078_RS04710 -4.8 -15.1 DUF4954 family protein compare
HMPREF1078_RS14285 -4.8 -3.3 IMP dehydrogenase compare
HMPREF1078_RS13530 -4.8 -14.5 pyridoxal phosphate-dependent aminotransferase compare
HMPREF1078_RS09885 -4.8 -13.7 alpha amylase C-terminal domain-containing protein compare
HMPREF1078_RS11820 -4.7 -9.1 M28 family peptidase compare
HMPREF1078_RS10280 -4.7 -3.2 energy transducer TonB compare
HMPREF1078_RS00125 -4.6 -7.9 phosphoribosylanthranilate isomerase compare
HMPREF1078_RS11090 -4.4 -6.7 6-phosphofructokinase compare
HMPREF1078_RS16650 -4.4 -15.9 alpha-isopropylmalate synthase regulatory domain-containing protein compare
HMPREF1078_RS14665 -4.3 -17.7 glycoside hydrolase family 57 protein compare
HMPREF1078_RS13915 -4.3 -13.0 tetratricopeptide repeat protein compare
HMPREF1078_RS07215 -4.3 -13.7 2-oxoacid:acceptor oxidoreductase subunit alpha compare
HMPREF1078_RS13965 -4.3 -1.6 AIR synthase-related protein compare
HMPREF1078_RS13375 -4.2 -15.6 NADP-specific glutamate dehydrogenase compare
HMPREF1078_RS16685 -4.2 -8.8 acetolactate synthase small subunit compare
HMPREF1078_RS11105 -4.2 -6.4 type IX secretion system protein PorQ compare
HMPREF1078_RS06560 -4.1 -25.4 two-component regulator propeller domain-containing protein compare
HMPREF1078_RS11010 -4.1 -14.3 hypothetical protein compare
HMPREF1078_RS17540 -4.1 -11.5 glycosyltransferase family 2 protein compare
HMPREF1078_RS16665 -4.1 -12.0 2-isopropylmalate synthase compare
HMPREF1078_RS16645 -4.0 -6.7 methylglyoxal synthase compare
HMPREF1078_RS05835 -4.0 -3.2 M20 family metallo-hydrolase compare
HMPREF1078_RS04555 -3.9 -13.9 HAMP domain-containing sensor histidine kinase compare
HMPREF1078_RS04820 -3.9 -4.6 type IX secretion system outer membrane channel protein PorV compare
HMPREF1078_RS05505 -3.9 -5.3 gliding motility protein GldL compare
HMPREF1078_RS04840 -3.9 -17.3 type IX secretion system sortase PorU compare
HMPREF1078_RS15315 -3.9 -14.7 DUF4831 family protein compare
HMPREF1078_RS07220 -3.9 -12.7 2-oxoacid:ferredoxin oxidoreductase subunit beta compare
HMPREF1078_RS16710 -3.9 -3.8 chorismate synthase compare
HMPREF1078_RS07705 -3.8 -11.0 sugar transferase compare
HMPREF1078_RS13185 -3.8 -6.7 cytochrome c biogenesis protein CcdA compare
HMPREF1078_RS05510 -3.7 -5.7 gliding motility protein GldM compare
HMPREF1078_RS16525 -3.7 -2.4 tRNA-Pro compare
HMPREF1078_RS11005 -3.7 -19.9 tetratricopeptide repeat protein compare
HMPREF1078_RS14685 -3.7 -12.6 aspartate 1-decarboxylase compare
HMPREF1078_RS05515 -3.7 -7.8 gliding motility protein GldN compare
HMPREF1078_RS13700 -3.7 -2.3 DNA translocase FtsK compare
HMPREF1078_RS10565 -3.6 -8.0 arginine repressor compare
HMPREF1078_RS16595 -3.6 -13.4 HD domain-containing protein compare
HMPREF1078_RS11200 -3.6 -11.4 aspartate--ammonia ligase compare
HMPREF1078_RS10005 -3.6 -11.5 TonB-dependent receptor compare
HMPREF1078_RS05495 -3.6 -4.9 type IX secretion system membrane protein PorP/SprF compare
HMPREF1078_RS13995 -3.5 -14.5 hypothetical protein compare
HMPREF1078_RS05280 -3.5 -4.3 helix-turn-helix transcriptional regulator compare
HMPREF1078_RS10270 -3.4 -6.5 MotA/TolQ/ExbB proton channel family protein compare
HMPREF1078_RS05500 -3.4 -7.2 SUMF1/EgtB/PvdO family nonheme iron enzyme compare
HMPREF1078_RS11260 -3.4 -5.7 OmpH family outer membrane protein compare
HMPREF1078_RS10275 -3.4 -4.0 biopolymer transporter ExbD compare
HMPREF1078_RS05870 -3.4 -8.1 PglZ domain-containing protein compare
HMPREF1078_RS07165 -3.3 -3.2 glycosyltransferase family 9 protein compare
HMPREF1078_RS11310 -3.3 -5.5 polyketide cyclase compare
HMPREF1078_RS10265 -3.3 -9.7 pyridoxine 5'-phosphate synthase compare
HMPREF1078_RS02390 -3.3 -12.5 tetratricopeptide repeat protein compare
HMPREF1078_RS17255 -3.3 -14.7 HAMP domain-containing sensor histidine kinase compare
HMPREF1078_RS07160 -3.3 -3.2 DUF4254 domain-containing protein compare
HMPREF1078_RS06745 -3.2 -5.4 uroporphyrinogen-III synthase compare
HMPREF1078_RS00085 -3.2 -11.9 PIG-L family deacetylase compare
HMPREF1078_RS14210 -3.2 -3.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
HMPREF1078_RS06530 -3.2 -7.7 radical SAM protein compare
HMPREF1078_RS13020 -3.2 -14.7 cell surface protein SprA compare
HMPREF1078_RS03090 -3.1 -10.1 helix-turn-helix transcriptional regulator compare
HMPREF1078_RS05920 -3.1 -3.6 RNA polymerase factor sigma-54 compare
HMPREF1078_RS11275 -3.1 -3.6 DUF6089 family protein compare
HMPREF1078_RS02175 -3.0 -12.2 patatin-like phospholipase family protein compare
HMPREF1078_RS00220 -3.0 -20.0 tetratricopeptide repeat protein compare
HMPREF1078_RS04485 -3.0 -10.8 T9SS type A sorting domain-containing protein compare
HMPREF1078_RS14615 -2.9 -2.8 tetratricopeptide repeat protein compare
HMPREF1078_RS01865 -2.9 -5.2 tetratricopeptide repeat protein compare
HMPREF1078_RS15460 -2.9 -9.5 DUF3078 domain-containing protein compare
HMPREF1078_RS00075 -2.9 -11.7 glycosyltransferase compare
HMPREF1078_RS16160 -2.9 -12.6 gliding motility lipoprotein GldH compare
HMPREF1078_RS05620 -2.9 -14.1 tetratricopeptide repeat protein compare
HMPREF1078_RS07610 -2.9 -7.8 glycosyltransferase family 2 protein compare
HMPREF1078_RS07315 -2.9 -11.7 DegT/DnrJ/EryC1/StrS family aminotransferase compare
HMPREF1078_RS07845 -2.9 -2.0 pyruvate:ferredoxin (flavodoxin) oxidoreductase compare
HMPREF1078_RS10160 -2.8 -5.0 OmpA family protein compare
HMPREF1078_RS00060 -2.8 -2.6 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase compare
HMPREF1078_RS00925 -2.8 -10.7 UpxY family transcription antiterminator compare
HMPREF1078_RS06740 -2.8 -13.2 DUF4271 domain-containing protein compare
HMPREF1078_RS16790 -2.7 -5.5 S9 family peptidase compare
HMPREF1078_RS15845 -2.7 -5.8 copper homeostasis protein CutC compare
HMPREF1078_RS09965 -2.7 -8.6 SPOR domain-containing protein compare
HMPREF1078_RS16875 -2.7 -9.9 type I methionyl aminopeptidase compare
HMPREF1078_RS00505 -2.7 -2.6 RecQ family ATP-dependent DNA helicase compare
HMPREF1078_RS07320 -2.7 -9.4 Gfo/Idh/MocA family oxidoreductase compare
HMPREF1078_RS09490 -2.7 -1.8 PD-(D/E)XK nuclease family protein compare
HMPREF1078_RS00210 -2.7 -4.1 acyl-CoA carboxylase subunit beta compare
HMPREF1078_RS14540 -2.7 -14.4 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
HMPREF1078_RS13175 -2.6 -3.6 hypothetical protein compare
HMPREF1078_RS14655 -2.6 -10.0 glycogen debranching enzyme N-terminal domain-containing protein compare
HMPREF1078_RS13550 -2.6 -10.0 aspartate kinase compare
HMPREF1078_RS01830 -2.6 -2.5 MoxR family ATPase compare
HMPREF1078_RS17490 -2.6 -17.0 FdtA/QdtA family cupin domain-containing protein compare
HMPREF1078_RS00080 -2.6 -12.2 polysaccharide deacetylase family protein compare
HMPREF1078_RS04365 -2.5 -4.7 hypothetical protein compare
HMPREF1078_RS07885 -2.5 -11.0 hypothetical protein compare
HMPREF1078_RS13270 -2.5 -6.7 ATP-binding protein compare
HMPREF1078_RS17485 -2.5 -19.0 glycosyl transferase compare
HMPREF1078_RS00090 -2.5 -10.7 GNAT family N-acetyltransferase compare
HMPREF1078_RS11135 -2.5 -1.7 hypothetical protein compare
HMPREF1078_RS17650 -2.4 -4.4 hypothetical protein compare
HMPREF1078_RS17145 -2.4 -2.3 acetyl-CoA hydrolase/transferase family protein compare
HMPREF1078_RS09715 -2.4 -2.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
HMPREF1078_RS00215 -2.4 -2.8 biotin/lipoyl-binding protein compare
HMPREF1078_RS04805 -2.4 -7.5 UvrD-helicase domain-containing protein compare
HMPREF1078_RS06810 -2.4 -11.9 hypothetical protein compare
HMPREF1078_RS17495 -2.4 -19.5 DegT/DnrJ/EryC1/StrS family aminotransferase compare
HMPREF1078_RS10020 -2.4 -11.9 OadG family transporter subunit compare
HMPREF1078_RS16230 -2.4 -6.4 porin family protein compare
HMPREF1078_RS15325 -2.4 -7.4 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
HMPREF1078_RS16730 -2.4 -6.1 acyltransferase compare
HMPREF1078_RS01860 -2.4 -2.3 BatD family protein compare
HMPREF1078_RS14525 -2.4 -5.0 SurA N-terminal domain-containing protein compare
HMPREF1078_RS09305 -2.3 -2.1 hypothetical protein compare
HMPREF1078_RS15280 -2.3 -5.4 malonyl-ACP O-methyltransferase BioC compare
HMPREF1078_RS12115 -2.3 -6.1 thioredoxin compare
HMPREF1078_RS19150 -2.3 -5.6 4-phosphoerythronate dehydrogenase PdxB compare
HMPREF1078_RS15270 -2.3 -10.6 RIP metalloprotease RseP compare
HMPREF1078_RS10025 -2.2 -8.3 biotin/lipoyl-binding protein compare
HMPREF1078_RS10015 -2.2 -17.7 acyl-CoA carboxylase subunit beta compare
HMPREF1078_RS10030 -2.2 -16.2 sodium ion-translocating decarboxylase subunit beta compare
HMPREF1078_RS17040 -2.2 -3.7 DNA helicase RecQ compare
HMPREF1078_RS15275 -2.2 -6.7 dethiobiotin synthase compare
HMPREF1078_RS13930 -2.2 -7.6 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
HMPREF1078_RS14640 -2.2 -4.6 S41 family peptidase compare
HMPREF1078_RS09775 -2.2 -14.0 translocation/assembly module TamB compare
HMPREF1078_RS07725 -2.2 -8.7 single-stranded-DNA-specific exonuclease RecJ compare
HMPREF1078_RS11320 -2.2 -7.5 hypothetical protein compare
HMPREF1078_RS14995 -2.2 -13.6 BamA/TamA family outer membrane protein compare
HMPREF1078_RS04665 -2.1 -4.2 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH compare
HMPREF1078_RS13050 -2.1 -5.6 primosomal protein N' compare
HMPREF1078_RS05885 -2.1 -5.5 ribonuclease R compare
HMPREF1078_RS14680 -2.1 -3.4 pantoate--beta-alanine ligase compare
HMPREF1078_RS07855 -2.1 -2.0 branched-chain amino acid aminotransferase compare
HMPREF1078_RS16215 -2.1 -8.0 preprotein translocase subunit YajC compare
HMPREF1078_RS07850 -2.1 -11.4 AAA family ATPase compare
HMPREF1078_RS00400 -2.1 -1.1 N-acetylmuramoyl-L-alanine amidase compare
HMPREF1078_RS00795 -2.0 -10.7 sigma-70 family RNA polymerase sigma factor compare
HMPREF1078_RS10745 -2.0 -11.7 MlaD family protein compare
HMPREF1078_RS17125 -2.0 -9.7 permease-like cell division protein FtsX compare
HMPREF1078_RS05845 -1.9 -7.3 peptidoglycan DD-metalloendopeptidase family protein compare
HMPREF1078_RS13555 -1.9 -6.4 ATP-binding cassette domain-containing protein compare
HMPREF1078_RS11570 -1.9 -1.8 Mrp/NBP35 family ATP-binding protein compare
HMPREF1078_RS16175 -1.8 -4.8 diacylglycerol kinase family lipid kinase compare
HMPREF1078_RS14505 -1.8 -12.1 hypothetical protein compare
HMPREF1078_RS00190 -1.8 -8.6 OmpA family protein compare
HMPREF1078_RS00025 -1.8 -7.8 Rossmann-like and DUF2520 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Parabacteroides merdae CL09T00C40 in carbon source experiments

For carbon source Beta-Lactose across organisms