| gene | name | fitness | t score | description | |
---|
| Rv1129c | | -3.9 | -8.5 | Probable transcriptional regulator protein | compare |
| Rv1538c | | -3.9 | -9.4 | Probable L-aparaginase AnsA | compare |
| Rv3400 | | -3.3 | -11.1 | Probable hydrolase | compare |
| Rv3848 | | -3.2 | -3.2 | Probable conserved transmembrane protein | compare |
| Rv1131 | | -3.1 | -3.4 | Probable methylcitrate synthase PrpC | compare |
| Rv3810 | | -3.1 | -3.2 | Exported repetitive protein precursor PirG (cell surface protein) (EXP53) | compare |
| Rv3150 | | -3.0 | -6.3 | Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) | compare |
| Rv3148 | | -2.9 | -7.1 | Probable NADH dehydrogenase I (chain D) NuoD (NADH-ubiquinone oxidoreductase chain D) | compare |
| Rv1130 | | -2.8 | -6.5 | Possible methylcitrate dehydratase PrpD | compare |
| Rv1798 | | -2.7 | -1.6 | ESX conserved component EccA5. ESX-5 type VII secretion system protein. | compare |
| Rv0249c | | -2.7 | -7.2 | Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase) | compare |
| Rv0018c | | -2.7 | -4.9 | Phosphoserine/threonine phosphatase PstP | compare |
| Rv3149 | | -2.6 | -7.9 | Probable NADH dehydrogenase I (chain E) NuoE (NADH-ubiquinone oxidoreductase chain E) | compare |
| Rv3154 | | -2.6 | -6.1 | Probable NADH dehydrogenase I (chain J) NuoJ (NADH-ubiquinone oxidoreductase chain J) | compare |
| Rv3156 | | -2.6 | -11.5 | Probable NADH dehydrogenase I (chain L) NuoL (NADH-ubiquinone oxidoreductase chain L) | compare |
| Rv3152 | | -2.6 | -9.9 | Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) | compare |
| Rv2982c | | -2.5 | -5.1 | Probable glycerol-3-phosphate dehydrogenase [NAD(P)+] GpdA2 (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) | compare |
| Rv3145 | | -2.4 | -10.7 | Probable NADH dehydrogenase I (chain A) NuoA (NADH-ubiquinone oxidoreductase chain A) | compare |
| Rv2606c | | -2.4 | -4.0 | Possible pyridoxine biosynthesis protein SnzP | compare |
| Rv3147 | | -2.4 | -5.1 | Probable NADH dehydrogenase I (chain C) NuoC (NADH-ubiquinone oxidoreductase chain C) | compare |
| Rv2365c | | -2.3 | -1.0 | Conserved hypothetical protein | compare |
| Rv3146 | | -2.3 | -6.9 | Probable NADH dehydrogenase I (chain B) NuoB (NADH-ubiquinone oxidoreductase chain B) | compare |
| Rv1193 | | -2.3 | -5.4 | Probable fatty-acid-CoA ligase FadD36 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | compare |
| Rv2476c | | -2.3 | -5.2 | Probable NAD-dependent glutamate dehydrogenase Gdh (NAD-Gdh) (NAD-dependent glutamic dehydrogenase) | compare |
| Rv3229c | | -2.2 | -2.8 | Possible linoleoyl-CoA desaturase (delta(6)-desaturase) | compare |
| Rv3158 | | -2.2 | -10.4 | Probable NADH dehydrogenase I (chain N) NuoN (NADH-ubiquinone oxidoreductase chain N) | compare |
| Rv2292c | | -2.2 | -1.1 | Hypothetical protein | compare |
| Rv3153 | | -2.2 | -6.7 | Probable NADH dehydrogenase I (chain I) NuoI (NADH-ubiquinone oxidoreductase chain I) | compare |
| Rv3157 | | -2.2 | -5.5 | Probable NADH dehydrogenase I (chain M) NUOK (NADH-ubiquinone oxidoreductase chain M) | compare |
| Rv0248c | | -2.1 | -6.1 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) | compare |
| Rv0758 | | -2.0 | -2.9 | Possible two component system response sensor kinase membrane associated PhoR | compare |
| Rv0247c | | -2.0 | -1.0 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) | compare |
| Rv3143 | | -2.0 | -2.0 | Probable response regulator | compare |
| Rv0472c | | -2.0 | -4.4 | Probable transcriptional regulatory protein (possibly TetR-family) | compare |
| Rv0757 | | -2.0 | -2.2 | Possible two component system response transcriptional positive regulator PhoP | compare |
| Rv1085c | | -2.0 | -5.6 | Possible hemolysin-like protein | compare |
| Rv1291c | | -1.9 | -2.8 | Conserved hypothetical secreted protein | compare |
| Rv2583c | | -1.9 | -2.8 | Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) | compare |
| Rv0642c | | -1.9 | -3.4 | Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) | compare |
| Rv3066 | | -1.9 | -5.7 | Probable transcriptional regulatory protein (probably DeoR-family) | compare |
| Rv1272c | | -1.9 | -9.2 | Probable drugs-transport transmembrane ATP-binding protein ABC transporter | compare |
| Rv0871 | | -1.8 | -2.4 | Probable cold shock-like protein B CspB | compare |
| Rv1890c | | -1.8 | -1.7 | Hypothetical protein | compare |
| Rv3151 | | -1.8 | -4.1 | Probable NADH dehydrogenase I (chain G) NuoG (NADH-ubiquinone oxidoreductase chain G) | compare |
| Rv1512 | | -1.8 | -1.0 | Probable nucleotide-sugar epimerase EpiA | compare |
| Rv0408 | | -1.8 | -5.8 | Probable phosphate acetyltransferase Pta (phosphotransacetylase) | conserved |
| Rv0280 | | -1.8 | -10.5 | PPE family protein PPE3 | compare |
| Rv1410c | | -1.8 | -9.8 | Aminoglycosides/tetracycline-transport integral membrane protein | compare |
| Rv3102c | | -1.7 | -3.1 | Putative cell division ATP-binding protein FtsE (septation component-transport ATP-binding protein ABC transporter) | compare |
| Rv1578c | | -1.7 | -1.0 | Probable PhiRv1 phage protein | compare |
| Rv1590 | | -1.7 | -4.2 | Conserved hypothetical protein | compare |
| Rv0056 | | -1.7 | -2.2 | 50S ribosomal protein L9 RplI | compare |
| Rv0190 | | -1.6 | -4.8 | Conserved protein | compare |
| Rv3321c | | -1.6 | -1.5 | Possible antitoxin VapB44 | compare |
| Rv1569 | | -1.6 | -3.9 | Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase) | compare |
| Rv1127c | | -1.6 | -1.5 | Probable pyruvate, phosphate dikinase PpdK | compare |
| Rv2869c | | -1.6 | -2.5 | Membrane bound metalloprotease | compare |
| Rv1568 | | -1.6 | -8.0 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | compare |
| Rv1159 | | -1.6 | -3.7 | Mannosyltransferase PimE | compare |
| Rv1836c | | -1.5 | -2.3 | Conserved protein | compare |
| Rv1565c | | -1.5 | -6.6 | Conserved hypothetical membrane protein | compare |
| Rv3816c | | -1.5 | -1.0 | Possible acyltransferase | compare |
| Rv3610c | | -1.5 | -2.2 | Membrane-bound protease FtsH (cell division protein) | compare |
| Rv1273c | | -1.4 | -3.4 | Probable drugs-transport transmembrane ATP-binding protein ABC transporter | compare |
| Rv1058 | | -1.4 | -5.9 | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | compare |
| Rv0346c | | -1.4 | -9.1 | Possible L-asparagine permease AnsP2 (L-asparagine transport protein) | compare |
| Rv0437c | | -1.4 | -0.7 | Possible phosphatidylserine decarboxylase Psd (PS decarboxylase) | compare |
| Rv1364c | | -1.4 | -5.2 | Possible sigma factor regulatory protein | compare |
| Rv2224c | | -1.4 | -8.9 | Probable carboxylesterase CaeA | compare |
| Rv1898 | | -1.4 | -2.2 | Conserved hypothetical protein | compare |
| Rv3230c | | -1.4 | -3.2 | Hypothetical oxidoreductase | compare |
| Rv1626 | | -1.4 | -3.4 | Probable two-component system transcriptional regulator | compare |
| Rv0409 | | -1.4 | -3.8 | Probable acetate kinase AckA (acetokinase) | compare |
| Rv3267 | | -1.4 | -3.2 | Conserved protein (CPSA-related protein) | compare |
| Rv2374c | | -1.3 | -2.8 | Probable heat shock protein transcriptional repressor HrcA | compare |
| Rv0995 | | -1.3 | -1.3 | Ribosomal-protein-alanine acetyltransferase RimJ (acetylating enzyme for N-terminal of ribosomal protein S5) | compare |
| Rv2170 | | -1.3 | -1.7 | GCN5-related N-acetyltransferase | compare |
| Rv0391 | | -1.3 | -5.7 | Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) | compare |
| Rv1821 | | -1.3 | -3.3 | Possible preprotein translocase ATPase SecA2 | compare |
| Rv0990c | | -1.3 | -0.7 | Hypothetical protein | compare |
| Rv2444c | | -1.3 | -2.7 | Possible ribonuclease E Rne | compare |
| Rv1570 | | -1.3 | -1.9 | Dethiobiotin synthetase BioD | compare |
| Rv0741 | | -1.3 | -2.1 | Probable transposase (fragment) | compare |
| Rv2048c | | -1.3 | -6.1 | Polyketide synthase Pks12 | compare |
| Rv2635 | | -1.3 | -0.7 | Hypothetical protein | compare |
| Rv2047c | | -1.3 | -5.3 | Conserved hypothetical protein | compare |
| Rv0275c | | -1.3 | -2.0 | Possible transcriptional regulatory protein (possibly TetR-family) | compare |
| Rv2862A | | -1.3 | -2.7 | Possible antitoxin VapB23 | compare |
| Rv0407 | | -1.2 | -4.0 | F420-dependent glucose-6-phosphate dehydrogenase Fgd1 | compare |
| Rv1589 | | -1.2 | -3.3 | Probable biotin synthetase BioB | compare |
| Rv0876c | | -1.2 | -2.0 | Possible conserved transmembrane protein | compare |
| Rv0321 | | -1.2 | -1.8 | Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase) | compare |
| Rv3575c | | -1.2 | -5.4 | Transcriptional regulatory protein (probably LacI-family) | compare |
| Rv3101c | | -1.2 | -2.4 | Putative cell division protein FtsX (septation component-transport integral membrane protein ABC transporter) | compare |
| Rv2788 | | -1.2 | -2.3 | Probable transcriptional repressor SirR | compare |
| Rv3823c | | -1.2 | -7.6 | Conserved integral membrane transport protein MmpL8 | compare |
| Rv0436c | | -1.2 | -1.7 | Probable CDP-diacylglycerol--serine O-phosphatidyltransferase PssA (PS synthase) (phosphatidylserine synthase) | compare |
| Rv3193c | | -1.2 | -1.5 | Probable conserved transmembrane protein | compare |
| Rv3478 | | -1.2 | -2.4 | PE family protein PPE60 | compare |
| Rv3513c | | -1.2 | -0.9 | Probable fatty-acid-CoA ligase FadD18 (fragment) (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | compare |
| Rv2506 | | -1.1 | -2.1 | Probable transcriptional regulatory protein (probably TetR-family) | compare |
| Rv1013 | | -1.1 | -6.7 | Putative polyketide synthase Pks16 | compare |
| Rv0016c | | -1.1 | -2.4 | Probable penicillin-binding protein PbpA | compare |
| Rv2745c | | -1.1 | -1.8 | Transcriptional regulatory protein ClgR | compare |
| Rv0504c | | -1.1 | -1.6 | Conserved protein | compare |
| Rv3136 | | -1.1 | -4.3 | PPE family protein PPE51 | compare |
| Rv0955 | | -1.1 | -1.0 | Probable conserved integral membrane protein | compare |
| Rv0390 | | -1.1 | -3.0 | Conserved protein | compare |
| Rv2588c | | -1.1 | -1.7 | Probable conserved membrane protein secretion factor YajC | compare |
| Rv3033 | | -1.0 | -0.5 | Unknown protein | compare |
| Rv3650 | | -1.0 | -0.6 | PE family protein PE33 | compare |
| Rv1531 | | -1.0 | -1.6 | Conserved protein | compare |
| Rv1946c | | -1.0 | -1.9 | Possible lipoprotein | compare |
| Rv3085 | | -1.0 | -0.5 | Probable short-chain type dehydrogenase/reductase | compare |
| Rv0204c | | -1.0 | -2.8 | Probable conserved transmembrane protein | compare |
| Rv0200 | | -1.0 | -1.8 | Possible conserved transmembrane protein | compare |
| Rv3140 | | -1.0 | -4.1 | Probable acyl-CoA dehydrogenase FadE23 | compare |
| Rv2417c | | -1.0 | -2.1 | Conserved protein | compare |
| Rv0043c | | -1.0 | -1.4 | Probable transcriptional regulatory protein (probably GntR-family) | compare |
| Rv2657c | | -1.0 | -1.0 | Probable PhiRv2 prophage protein | compare |
| Rv0545c | | -1.0 | -2.9 | Probable low-affinity inorganic phosphate transporter integral membrane protein PitA | compare |
| Rv1183 | | -1.0 | -4.3 | Probable conserved transmembrane transport protein MmpL10 | compare |
| Rv1072 | | -1.0 | -1.1 | Probable conserved transmembrane protein | compare |
| Rv2154c | | -1.0 | -1.6 | FtsW-like protein FtsW | compare |
| Rv0400c | | -1.0 | -2.2 | Acyl-CoA dehydrogenase FadE7 | compare |
| Rv0161 | | -1.0 | -2.3 | Possible oxidoreductase | compare |
| Rv3358 | | -1.0 | -1.8 | Toxin RelK | compare |
| Rv1332 | | -1.0 | -1.4 | Probable transcriptional regulatory protein | compare |
| Rv0344c | | -1.0 | -2.3 | Probable lipoprotein LpqJ | compare |
| Rv3139 | | -1.0 | -4.2 | Probable acyl-CoA dehydrogenase FadE24 | compare |
| Rv3249c | | -1.0 | -0.8 | Possible transcriptional regulatory protein (probably TetR-family) | compare |
| Rv3420c | | -0.9 | -2.2 | Ribosomal-protein-alanine acetyltransferase RimI (acetylating enzyme for N-terminal of ribosomal protein S18) | compare |
| Rv2736c | | -0.9 | -1.6 | Regulatory protein RecX | compare |
| Rv0017c | | -0.9 | -3.0 | Probable cell division protein RodA | compare |
| Rv3803c | | -0.9 | -4.4 | Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) | compare |
| Rv3868 | | -0.9 | -5.9 | ESX conserved component EccA1. ESX-1 type VII secretion system protein. | compare |
| Rv0989c | | -0.9 | -4.3 | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | compare |
| Rv2384 | | -0.9 | -2.1 | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | compare |
| Rv1640c | | -0.9 | -4.7 | Lysyl-tRNA synthetase 2 LysX | compare |
| Rv1286 | | -0.9 | -2.2 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + adenylylsulfate kinase | compare |
| Rv2605c | | -0.9 | -2.2 | Probable acyl-CoA thioesterase II TesB2 (TEII) | compare |
| Rv1053c | | -0.9 | -0.7 | Hypothetical protein | compare |
| Rv0819 | | -0.9 | -2.4 | GCN5-related N-acetyltransferase, MshD | compare |
| Rv2064 | | -0.9 | -2.8 | Precorrin-3B synthase CobG | compare |
| Rv3374 | | -0.9 | -1.5 | Probable enoyl-CoA hydratase (fragment) EchA18.1 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) | compare |
| Rv2429 | | -0.9 | -1.0 | Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D) | compare |
| Rv2550c | | -0.9 | -2.0 | Possible antitoxin VapB20 | compare |
| Rv0655 | | -0.9 | -2.7 | Possible ribonucleotide-transport ATP-binding protein ABC transporter Mkl | compare |
| Rv1411c | | -0.9 | -2.2 | Conserved lipoprotein LprG | compare |
| Rv2774c | | -0.9 | -0.8 | Hypothetical protein | compare |
| Rv3416 | | -0.8 | -1.1 | Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster. | compare |
| Rv1791 | | -0.8 | -1.1 | PE family protein PE19 | compare |
| Rv2694c | | -0.8 | -3.4 | Conserved protein | compare |
| Rv3200c | | -0.8 | -2.2 | Possible transmembrane cation transporter | compare |
| Rv3477 | | -0.8 | -1.2 | PE family protein PE31 | compare |
| Rv2029c | | -0.8 | -1.3 | 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) | compare |
| Rv2691 | | -0.8 | -3.7 | TRK system potassium uptake protein CeoB | compare |
| Rv1940 | | -0.8 | -2.1 | Probable riboflavin biosynthesis protein RibA1 (GTP cyclohydrolase II) | compare |
| Rv0019c | | -0.8 | -2.7 | Conserved protein with FHA domain, FhaB | compare |
| Rv2707 | | -0.8 | -5.1 | Probable conserved transmembrane alanine and leucine rich protein | compare |
| Rv2661c | | -0.8 | -1.4 | Hypothetical protein | compare |
| Rv0825c | | -0.8 | -1.3 | Conserved protein | compare |
| Rv0744c | | -0.8 | -2.5 | Possible transcriptional regulatory protein | compare |
| Rv3306c | | -0.8 | -1.0 | Probable amidohydrolase AmiB1 (aminohydrolase) | compare |
| Rv1096 | | -0.8 | -0.8 | Possible glycosyl hydrolase | compare |
| Rv0135c | | -0.8 | -2.8 | Possible transcriptional regulatory protein | compare |
| Rv0202c | | -0.8 | -5.1 | Probable conserved transmembrane transport protein MmpL11 | compare |
| Rv0328 | | -0.8 | -0.9 | Possible transcriptional regulatory protein (possibly TetR/AcrR-family) | compare |
| Rv1276c | | -0.8 | -2.1 | Conserved hypothetical protein | compare |
| Rv0820 | | -0.8 | -3.4 | Probable phosphate-transport ATP-binding protein ABC transporter PhoT | compare |
| Rv1097c | | -0.8 | -1.5 | Probable membrane glycine and proline rich protein | compare |
| Rv1025 | | -0.8 | -0.6 | Conserved protein | compare |
| Rv2427c | | -0.8 | -2.4 | Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) | compare |
| Rv1895 | | -0.8 | -1.6 | Possible dehydrogenase | compare |
| Rv2722 | | -0.8 | -3.3 | Conserved hypothetical protein | compare |
| Rv3045 | | -0.8 | -2.8 | Probable NADP-dependent alcohol dehydrogenase AdhC | compare |
| Rv1620c | | -0.8 | -1.5 | Probable 'component linked with the assembly of cytochrome' transport transmembrane ATP-binding protein ABC transporter CydC | compare |
| Rv0497 | | -0.8 | -1.2 | Probable conserved transmembrane protein | compare |
| Rv2553c | | -0.8 | -0.7 | Probable conserved membrane protein | compare |
| Rv1829 | | -0.8 | -3.9 | Conserved protein | compare |
| Rv1160 | | -0.7 | -1.4 | Probable mutator protein MutT2 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) | compare |
| Rv0413 | | -0.7 | -3.5 | Possible mutator protein MutT3 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) | compare |
| Rv3919c | | -0.7 | -1.8 | Probable glucose-inhibited division protein B Gid | compare |
| Rv2462c | | -0.7 | -3.7 | Probable trigger factor (TF) protein Tig | compare |
| Rv2252 | | -0.7 | -0.5 | Diacylglycerol kinase | compare |
| Rv0930 | | -0.7 | -4.4 | Probable phosphate-transport integral membrane ABC transporter PstA1 | compare |
| Rv3050c | | -0.7 | -2.6 | Probable transcriptional regulatory protein (probably AsnC-family) | compare |
| Rv0113 | | -0.7 | -1.0 | Probable sedoheptulose-7-phosphate isomerase GmhA (phosphoheptose isomerase) | compare |
| Rv3433c | | -0.7 | -1.5 | Conserved protein | compare |
| Rv1694 | | -0.7 | -1.0 | 2'-O-methyltransferase TlyA | compare |
| Rv1657 | | -0.7 | -0.9 | Probable arginine repressor ArgR (AHRC) | compare |
| Rv3723 | | -0.7 | -2.6 | Probable conserved transmembrane protein | compare |
| Rv3543c | | -0.7 | -2.4 | Probable acyl-CoA dehydrogenase FadE29 | compare |
| Rv0452 | | -0.7 | -2.5 | Possible transcriptional regulatory protein | compare |
| Rv2696c | | -0.7 | -1.7 | Conserved alanine and glycine and valine rich protein | compare |
| Rv3540c | | -0.7 | -1.9 | Probable lipid transfer protein or keto acyl-CoA thiolase Ltp2 | compare |
| Rv2502c | | -0.7 | -3.7 | Probable acetyl-/propionyl-CoA carboxylase (beta subunit) AccD1 | compare |
| Rv2205c | | -0.7 | -2.7 | Conserved hypothetical protein | compare |
| Rv0877 | | -0.7 | -4.6 | Conserved hypothetical protein | compare |
| Rv3833 | | -0.7 | -1.5 | Transcriptional regulatory protein (probably AraC-family) | compare |