Experiment set1IT092 for Pseudomonas fluorescens FW300-N2E3

Compare to:

LB with Cobalt chloride hexahydrate 0.32 mM

200 most detrimental genes:

  gene name fitness t score description  
AO353_02945 +9.5 40.5 magnesium transporter compare
AO353_15450 +2.7 21.4 ubiquinol oxidase subunit II compare
AO353_09865 +2.5 19.3 hypothetical protein compare
AO353_06390 +2.0 9.1 magnesium transporter compare
AO353_00495 +1.9 4.3 DNA topoisomerase I compare
AO353_15470 +1.7 13.8 protoheme IX farnesyltransferase compare
AO353_04955 +1.6 10.0 dihydrofolate reductase conserved
AO353_15465 +1.5 9.2 cytochrome C oxidase compare
AO353_15455 +1.4 11.7 cytochrome o ubiquinol oxidase subunit I compare
AO353_15460 +1.3 7.4 cytochrome o ubiquinol oxidase subunit III compare
AO353_21400 +1.3 4.0 conjugal transfer protein TraR compare
AO353_18325 +1.3 2.8 hypothetical protein compare
AO353_01410 +1.2 3.8 ribonuclease E compare
AO353_03795 +1.2 2.2 fumarate hydratase compare
AO353_08210 +1.2 5.0 tRNA (guanine-N7)-methyltransferase compare
AO353_12460 +1.2 7.0 malate dehydrogenase compare
AO353_04965 +1.2 4.4 D-erythro-7,8-dihydroneopterin triphosphate epimerase compare
AO353_13640 +1.1 4.5 histidine kinase compare
AO353_06710 +1.1 1.9 riboflavin synthase subunit alpha compare
AO353_02100 +1.1 3.0 phosphoglycolate phosphatase compare
AO353_25585 +1.1 2.4 argininosuccinate lyase compare
AO353_14370 +1.1 6.7 glucose-6-phosphate isomerase compare
AO353_00115 +1.1 2.8 hypothetical protein compare
AO353_09720 +1.1 1.9 hypothetical protein compare
AO353_09905 +1.0 7.3 phosphate-binding protein compare
AO353_02070 +1.0 4.8 prephenate dehydratase compare
AO353_03605 +1.0 1.6 FmdB family transcriptional regulator compare
AO353_02950 +1.0 3.5 cell envelope protein SmpA compare
AO353_22985 +1.0 3.7 hypothetical protein compare
AO353_15875 +1.0 3.3 23S rRNA (adenine(2503)-C2)-methyltransferase compare
AO353_07365 +1.0 2.9 glycerol-3-phosphate acyltransferase compare
AO353_19685 +0.9 2.6 alkylhydroperoxidase compare
AO353_11945 +0.9 0.8 4-oxalocrotonate tautomerase compare
AO353_10890 +0.9 4.9 methionine ABC transporter ATP-binding protein compare
AO353_17750 +0.9 1.8 transcriptional regulator compare
AO353_06725 +0.9 1.2 hypothetical protein compare
AO353_04190 +0.9 2.5 glycerol-3-phosphate dehydrogenase compare
AO353_10885 +0.9 4.9 metal ABC transporter permease compare
AO353_09275 +0.9 1.7 DNA-directed RNA polymerase subunit omega compare
AO353_09785 +0.9 3.2 hypothetical protein compare
AO353_28725 +0.8 1.9 hypothetical protein compare
AO353_06775 +0.8 4.7 dTDP-4-dehydrorhamnose reductase compare
AO353_04400 +0.8 5.6 transporter compare
AO353_07610 +0.8 1.8 hypothetical protein compare
AO353_15170 +0.8 2.3 cytochrome D ubiquinol oxidase subunit III compare
AO353_19280 +0.8 2.0 hypothetical protein compare
AO353_11850 +0.8 3.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
AO353_10510 +0.8 1.6 benzoate transporter compare
AO353_08440 +0.8 2.2 hypothetical protein compare
AO353_27710 +0.8 0.8 DNA repair protein compare
AO353_24810 +0.8 3.2 transcriptional regulator compare
AO353_07140 +0.8 6.3 peptidase M23 compare
AO353_17085 +0.7 2.0 hypothetical protein compare
AO353_26285 +0.7 1.4 hypothetical protein compare
AO353_06745 +0.7 1.9 zinc-binding protein compare
AO353_02935 +0.7 3.1 ribose-phosphate pyrophosphokinase compare
AO353_23370 +0.7 2.5 cytochrome C compare
AO353_13420 +0.7 1.1 hypothetical protein compare
AO353_14395 +0.7 2.3 poly(A) polymerase compare
AO353_15185 +0.7 2.5 ATPase compare
AO353_16375 +0.7 2.3 hypothetical protein compare
AO353_07875 +0.7 2.1 hypothetical protein compare
AO353_26115 +0.7 1.0 hypothetical protein compare
AO353_05240 +0.7 2.3 rod shape-determining protein MreD compare
AO353_02465 +0.7 1.7 hypothetical protein compare
AO353_19030 +0.7 3.6 phospho-2-dehydro-3-deoxyheptonate aldolase compare
AO353_18780 +0.7 3.4 cobyrinic acid a,c-diamide synthase compare
AO353_13570 +0.7 4.6 TonB-dependent receptor compare
AO353_26935 +0.7 1.6 LysR family transcriptional regulator compare
AO353_26865 +0.6 1.9 transcriptional regulator compare
AO353_27380 +0.6 1.3 pyocin R2, holin compare
AO353_00105 +0.6 1.0 hypothetical protein compare
AO353_17305 +0.6 3.3 TetR family transcriptional regulator compare
AO353_08605 +0.6 3.3 type I pantothenate kinase compare
AO353_24440 +0.6 1.0 reactive intermediate/imine deaminase compare
AO353_28640 +0.6 2.1 hypothetical protein compare
AO353_08855 +0.6 2.3 GntR family transcriptional regulator compare
AO353_17885 +0.6 1.2 hypothetical protein compare
AO353_29085 +0.6 3.5 methyltransferase compare
AO353_27875 +0.6 3.1 exonuclease III compare
AO353_16025 +0.6 2.2 hypothetical protein compare
AO353_23015 +0.6 2.0 histidine kinase compare
AO353_08215 +0.6 2.6 thiazole synthase compare
AO353_19020 +0.6 1.2 hypothetical protein compare
AO353_03815 +0.6 1.7 heme utilization protein compare
AO353_14085 +0.6 1.6 hypothetical protein compare
AO353_27825 +0.6 1.3 peptidylprolyl isomerase compare
AO353_23510 +0.6 2.0 transcriptional regulator compare
AO353_08130 +0.6 1.3 uracil phosphoribosyltransferase compare
AO353_09500 +0.6 3.2 hypothetical protein compare
AO353_01725 +0.6 1.6 phosphohistidine phosphatase compare
AO353_03775 +0.6 3.9 pyruvate kinase compare
AO353_12565 +0.6 1.4 type II secretion system protein GspH compare
AO353_02330 +0.6 2.1 allantoicase compare
AO353_25330 +0.6 2.3 biotin-independent malonate decarboxylase subunit beta compare
AO353_29355 +0.6 1.8 hypothetical protein compare
AO353_16355 +0.6 2.3 TetR family transcriptional regulator compare
AO353_24425 +0.6 1.0 amino acid ABC transporter permease compare
AO353_07695 +0.6 2.1 electron transfer flavoprotein subunit beta compare
AO353_27575 +0.6 1.8 hypothetical protein compare
AO353_13800 +0.6 1.9 hypothetical protein compare
AO353_23580 +0.6 2.7 ACP phosphodiesterase compare
AO353_22955 +0.6 2.0 tRNA hydroxylase compare
AO353_26870 +0.6 1.7 AP endonuclease compare
AO353_14260 +0.6 2.6 50s ribosomal protein l13 compare
AO353_17155 +0.6 4.3 RNA polymerase-associated protein RapA compare
AO353_25000 +0.6 2.5 magnesium transporter compare
AO353_05810 +0.6 1.9 dehydrogenase compare
AO353_16345 +0.6 1.2 energy transducer TonB compare
AO353_27440 +0.6 2.1 hypothetical protein compare
AO353_16015 +0.6 3.5 tRNA (mo5U34)-methyltransferase compare
AO353_04845 +0.6 3.7 LysR family transcriptional regulator compare
AO353_10990 +0.6 3.4 glutamate:protein symporter compare
AO353_03515 +0.6 1.1 cold-shock protein compare
AO353_27985 +0.6 1.7 peptidase M14 compare
AO353_00760 +0.5 1.3 hypothetical protein compare
AO353_15595 +0.5 1.2 hypothetical protein compare
AO353_28035 +0.5 2.0 hypothetical protein compare
AO353_07445 +0.5 1.5 pyrroloquinoline quinone biosynthesis protein PqqD compare
AO353_13050 +0.5 1.9 DNA topoisomerase IV compare
AO353_24095 +0.5 2.0 multidrug DMT transporter permease compare
AO353_12790 +0.5 0.9 hypothetical protein compare
AO353_20965 +0.5 2.7 hypothetical protein compare
AO353_02815 +0.5 2.0 transcriptional regulator compare
AO353_01310 +0.5 2.4 radical SAM protein compare
AO353_17935 +0.5 1.3 hypothetical protein compare
AO353_20535 +0.5 1.1 hypothetical protein compare
AO353_02220 +0.5 1.0 hypothetical protein compare
AO353_26055 +0.5 1.4 hypothetical protein compare
AO353_25355 +0.5 1.3 hypothetical protein compare
AO353_27920 +0.5 2.1 arginine N-succinyltransferase compare
AO353_00065 +0.5 1.7 oxidoreductase compare
AO353_09595 +0.5 2.2 hypothetical protein compare
AO353_24255 +0.5 1.9 hypothetical protein compare
AO353_12535 +0.5 1.8 hypothetical protein compare
AO353_17965 +0.5 2.2 hypothetical protein compare
AO353_20790 +0.5 1.5 penicillin-binding protein activator LpoB compare
AO353_18095 +0.5 2.0 hypothetical protein compare
AO353_03285 +0.5 2.2 GCN5 family acetyltransferase compare
AO353_09870 +0.5 3.3 peptidase M23 compare
AO353_26985 +0.5 2.5 hypothetical protein compare
AO353_03830 +0.5 0.9 antibiotic biosynthesis monooxygenase compare
AO353_17450 +0.5 2.1 hypothetical protein compare
AO353_24185 +0.5 2.2 serine/threonine protein phosphatase compare
AO353_14590 +0.5 1.0 serine kinase/phosphatase compare
AO353_16955 +0.5 2.2 succinylglutamate desuccinylase compare
AO353_11280 +0.5 2.1 phage tail protein compare
AO353_05230 +0.5 3.1 ribonuclease G compare
AO353_22905 +0.5 3.7 RND transporter compare
AO353_11135 +0.5 1.7 polyketide cyclase compare
AO353_21445 +0.5 1.5 cation:proton antiporter compare
AO353_15605 +0.5 1.9 histidine kinase compare
AO353_19180 +0.5 1.7 GAF domain-containing protein compare
AO353_09400 +0.5 1.4 hypothetical protein compare
AO353_20810 +0.5 0.7 hypothetical protein compare
AO353_18630 +0.5 3.2 beta-ketoacyl-ACP synthase compare
AO353_27895 +0.5 2.2 isochorismatase compare
AO353_16020 +0.5 1.6 tRNA (cmo5U34)-methyltransferase compare
AO353_02000 +0.5 1.6 polysaccharide/polyol phosphate ABC transporter ATP-binding protein compare
AO353_13415 +0.5 2.9 TetR family transcriptional regulator compare
AO353_21180 +0.5 1.8 transposase compare
AO353_12950 +0.5 2.1 polymerase compare
AO353_25845 +0.5 1.3 GNAT family acetyltransferase compare
AO353_21240 +0.5 2.3 undecaprenyl-phosphate glucose phosphotransferase compare
AO353_02715 +0.5 1.5 23S rRNA methyltransferase compare
AO353_09705 +0.5 1.0 hypothetical protein compare
AO353_29005 +0.5 1.3 hypothetical protein compare
AO353_17005 +0.5 1.0 hypothetical protein compare
AO353_06365 +0.5 3.5 hypothetical protein compare
AO353_22010 +0.5 1.6 hypothetical protein compare
AO353_08375 +0.5 1.9 hypothetical protein compare
AO353_14010 +0.5 1.7 GntR family transcriptional regulator compare
AO353_27090 +0.5 0.8 hypothetical protein compare
AO353_20005 +0.5 2.1 phosphoribosyl transferase compare
AO353_11545 +0.5 2.3 sulfate ABC transporter permease compare
AO353_09505 +0.5 1.3 hypothetical protein compare
AO353_15425 +0.5 2.2 GNAT family acetyltransferase compare
AO353_27890 +0.5 2.0 RpiR family transcriptional regulator compare
AO353_23405 +0.5 0.8 hypothetical protein compare
AO353_29365 +0.4 1.0 paraquat-inducible protein A compare
AO353_24405 +0.4 1.0 ArsR family transcriptional regulator compare
AO353_06400 +0.4 1.6 hypothetical protein compare
AO353_14570 +0.4 2.0 chromosome partitioning protein compare
AO353_28530 +0.4 2.2 diguanylate cyclase compare
AO353_13450 +0.4 2.6 AraC family transcriptional regulator compare
AO353_26210 +0.4 1.8 hypothetical protein compare
AO353_28810 +0.4 2.1 acetyl-CoA carboxylase biotin carboxylase subunit compare
AO353_09830 +0.4 2.8 pyridine nucleotide-disulfide oxidoreductase compare
AO353_04970 +0.4 0.9 cell division protein DedD compare
AO353_05485 +0.4 2.6 Fructose-specific PTS system, I, HPr, and IIA components (from data) compare
AO353_12580 +0.4 1.3 type II secretory protein PulK compare
AO353_12135 +0.4 1.3 rRNA methylase compare
AO353_05060 +0.4 1.7 pressure-regulated protein compare
AO353_27315 +0.4 2.1 hypothetical protein compare
AO353_28200 +0.4 1.7 ribosomal protein S3AE compare
AO353_09750 +0.4 2.5 hypothetical protein compare
AO353_23005 +0.4 1.0 hypothetical protein compare
AO353_24300 +0.4 1.8 transcriptional regulator compare
AO353_10620 +0.4 1.5 hypothetical protein compare
AO353_03130 +0.4 1.0 hypothetical protein compare


Specific Phenotypes

For 7 genes in this experiment

For stress Cobalt chloride hexahydrate in Pseudomonas fluorescens FW300-N2E3

For stress Cobalt chloride hexahydrate across organisms