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Experiment set1IT059 for
Methanococcus maripaludis JJ
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H2 pooled triplicate biofilm cells
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS04200
-5.5
-7.5
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS01810
-5.1
-1.9
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS04800
-4.7
-7.2
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS02045
-4.7
-3.2
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS01865
-4.6
-6.7
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS04970
-4.5
-2.0
DUF655 domain-containing protein
compare
MMJJ
_RS03670
-4.4
-6.0
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS00210
-4.3
-2.9
DUF530 family protein
compare
MMJJ
_RS04155
-4.3
-8.6
hypothetical protein
compare
MMJJ
_RS03620
-4.3
-7.1
DUF2097 domain-containing protein
compare
MMJJ
_RS06625
-4.2
-1.8
pyruvate synthase subunit PorB
compare
MMJJ
_RS00450
-4.1
-1.8
DUF126 domain-containing protein
compare
MMJJ
_RS04150
-4.1
-3.5
DUF5379 domain-containing protein
compare
MMJJ
_RS06695
-4.1
-2.3
amidohydrolase
compare
MMJJ
_RS08660
-4.0
-2.6
acetylornithine transaminase
compare
MMJJ
_RS03785
-4.0
-2.3
hypothetical protein
compare
MMJJ
_RS00425
-3.9
-4.7
hypothetical protein
compare
MMJJ
_RS06485
-3.9
-2.4
phosphoglycerate kinase
compare
MMJJ
_RS08095
-3.9
-4.6
cobyric acid synthase CobQ
compare
MMJJ
_RS08320
-3.9
-3.1
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS03310
-3.9
-2.6
hypothetical protein
compare
MMJJ
_RS05650
-3.9
-3.1
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS04685
-3.9
-11.7
carbamoyltransferase HypF
compare
MMJJ
_RS04050
-3.9
-1.9
dihydroneopterin aldolase family protein
compare
MMJJ
_RS06390
-3.9
-1.7
NADPH-dependent F420 reductase
compare
MMJJ
_RS03760
-3.8
-4.0
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS09135
-3.8
-10.6
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS06110
-3.7
-3.1
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS01690
-3.7
-4.0
methanogenesis marker 12 protein
compare
MMJJ
_RS03580
-3.7
-3.0
TIGR00303 family protein
compare
MMJJ
_RS03055
-3.7
-3.5
hypothetical protein
compare
MMJJ
_RS03615
-3.6
-3.6
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS01880
-3.6
-3.5
RlmE family RNA methyltransferase
compare
MMJJ
_RS05445
-3.6
-1.5
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS05415
-3.6
-1.7
hypothetical protein
compare
MMJJ
_RS07950
-3.6
-3.5
4Fe-4S binding protein
compare
MMJJ
_RS08840
-3.5
-4.2
calcium/sodium antiporter
compare
MMJJ
_RS07000
-3.5
-1.5
TrkH family potassium uptake protein
compare
MMJJ
_RS07725
-3.5
-6.9
DNA primase DnaG
compare
MMJJ
_RS03840
-3.4
-5.1
DHH family phosphoesterase
compare
MMJJ
_RS09190
-3.4
-1.8
tryptophan synthase subunit beta
compare
MMJJ
_RS00215
-3.4
-1.8
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS08850
-3.4
-3.2
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS01935
-3.4
-5.6
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS01750
-3.4
-1.8
ferrous iron transport protein A
compare
MMJJ
_RS06180
-3.4
-2.9
tryptophan--tRNA ligase
compare
MMJJ
_RS07785
-3.4
-2.7
fumarate reductase subunit A
compare
MMJJ
_RS03815
-3.4
-2.3
nascent polypeptide-associated complex protein
compare
MMJJ
_RS04980
-3.4
-5.7
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS03895
-3.3
-3.3
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS06155
-3.3
-6.9
phosphatidylglycerophosphatase A
compare
MMJJ
_RS01350
-3.3
-7.8
sodium:proton antiporter
compare
MMJJ
_RS06220
-3.3
-6.5
polyamine aminopropyltransferase
compare
MMJJ
_RS02920
-3.3
-2.3
30S ribosomal protein S27ae
compare
MMJJ
_RS06905
-3.2
-2.0
hypothetical protein
compare
MMJJ
_RS06725
-3.2
-13.7
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05330
-3.2
-2.5
DNA polymerase II large subunit
compare
MMJJ
_RS08080
-3.2
-8.8
TIGR00300 family protein
compare
MMJJ
_RS01755
-3.2
-2.4
ferrous iron transport protein B
compare
MMJJ
_RS08795
-3.2
-1.8
phosphoglucosamine mutase
compare
MMJJ
_RS00270
-3.2
-3.1
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS03155
-3.2
-11.5
hypothetical protein
compare
MMJJ
_RS06880
-3.2
-1.9
EhaG family protein
compare
MMJJ
_RS09375
-3.2
-2.0
hypothetical protein
compare
MMJJ
_RS05260
-3.2
-6.6
ATP-grasp domain-containing protein
compare
MMJJ
_RS07705
-3.2
-3.2
GTP-binding protein EngB
compare
MMJJ
_RS04790
-3.1
-4.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03875
-3.1
-4.5
CBS domain-containing protein
compare
MMJJ
_RS04145
-3.1
-8.7
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS07875
-3.1
-2.3
FAD-dependent oxidoreductase
compare
MMJJ
_RS00560
-3.1
-3.8
homoisocitrate dehydrogenase
compare
MMJJ
_RS04700
-3.1
-7.2
deoxyhypusine synthase
compare
MMJJ
_RS02090
-3.1
-4.6
tyramine--L-glutamate ligase
compare
MMJJ
_RS06040
-3.1
-4.3
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS05620
-3.1
-5.4
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS01360
-3.1
-1.6
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS05810
-3.1
-7.9
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS02055
-3.1
-11.9
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS01355
-3.1
-2.9
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS07265
-3.0
-12.6
tRNA (adenine-N1)-methyltransferase
compare
MMJJ
_RS00205
-3.0
-6.5
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS09175
-3.0
-0.9
anthranilate synthase component I
compare
MMJJ
_RS06255
-3.0
-6.9
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS08155
-3.0
-5.1
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS03190
-3.0
-3.0
phosphopyruvate hydratase
compare
MMJJ
_RS01870
-3.0
-2.9
methanogenesis marker 15 protein
compare
MMJJ
_RS07430
-3.0
-3.5
ribonuclease VapC
compare
MMJJ
_RS09055
-3.0
-9.5
NFACT family protein
compare
MMJJ
_RS00550
-3.0
-7.5
AIR synthase-related protein
compare
MMJJ
_RS00275
-3.0
-2.4
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03150
-3.0
-6.0
2-phospho-L-lactate transferase
compare
MMJJ
_RS00570
-3.0
-2.0
ribonuclease P
compare
MMJJ
_RS04730
-2.9
-3.0
tyrosine decarboxylase MfnA
compare
MMJJ
_RS05070
-2.9
-1.9
DNA primase catalytic subunit PriS
compare
MMJJ
_RS07720
-2.9
-2.2
UPF0058 family protein
compare
MMJJ
_RS01475
-2.9
-1.4
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS03820
-2.9
-3.4
hydrogenase formation protein HypD
compare
MMJJ
_RS04565
-2.9
-4.2
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS07245
-2.9
-6.3
amidohydrolase family protein
compare
MMJJ
_RS02275
-2.9
-4.4
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS01200
-2.9
-3.0
PRC-barrel domain-containing protein
compare
MMJJ
_RS03230
-2.9
-3.9
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS05655
-2.8
-7.6
HisA/HisF family protein
compare
MMJJ
_RS04110
-2.8
-6.9
hypothetical protein
compare
MMJJ
_RS05930
-2.8
-2.0
cell division protein SepF
compare
MMJJ
_RS00355
-2.8
-1.6
ribonuclease P protein component 4
compare
MMJJ
_RS03005
-2.8
-2.6
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS06805
-2.8
-3.6
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS07350
-2.8
-4.3
4Fe-4S binding protein
compare
MMJJ
_RS08855
-2.8
-3.8
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS02200
-2.8
-11.7
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS07505
-2.8
-1.0
DNA-directed RNA polymerase subunit K
compare
MMJJ
_RS01860
-2.8
-13.6
tRNA guanosine(15) transglycosylase TgtA
compare
MMJJ
_RS04505
-2.8
-7.3
CDC48 family AAA ATPase
compare
MMJJ
_RS04995
-2.7
-5.7
Tfx family DNA-binding protein
compare
MMJJ
_RS06240
-2.7
-2.2
dihydropteroate synthase-like protein
compare
MMJJ
_RS08055
-2.7
-8.4
methanogenesis marker 14 protein
compare
MMJJ
_RS00600
-2.7
-2.4
hydroxymethylbilane synthase
compare
MMJJ
_RS01415
-2.7
-2.3
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS03170
-2.7
-9.1
DUF5612 domain-containing protein
compare
MMJJ
_RS05610
-2.7
-4.4
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS07275
-2.7
-2.4
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS03865
-2.7
-1.9
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS00195
-2.7
-4.1
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS08340
-2.7
-5.3
archaeoflavoprotein AfpA
compare
MMJJ
_RS05950
-2.7
-3.4
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS04670
-2.7
-4.8
DUF2117 domain-containing protein
compare
MMJJ
_RS05155
-2.7
-6.4
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS00125
-2.6
-2.6
KEOPS complex subunit Cgi121
compare
MMJJ
_RS03125
-2.6
-5.2
GMC oxidoreductase
compare
MMJJ
_RS00265
-2.6
-7.7
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS08335
-2.6
-2.5
ABC transporter ATP-binding protein
compare
MMJJ
_RS06930
-2.6
-2.3
type II methionyl aminopeptidase
compare
MMJJ
_RS07995
-2.6
-6.1
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS06490
-2.6
-2.2
methanogenesis marker 2 protein
compare
MMJJ
_RS07375
-2.6
-8.7
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMJJ
_RS08620
-2.6
-4.4
DUF373 family protein
compare
MMJJ
_RS05490
-2.6
-2.6
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS03110
-2.6
-3.8
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS05595
-2.6
-3.5
hypothetical protein
compare
MMJJ
_RS06215
-2.6
-5.1
agmatinase
compare
MMJJ
_RS03065
-2.5
-12.3
CBS domain-containing protein
compare
MMJJ
_RS07410
-2.5
-3.6
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS06150
-2.5
-4.7
DUF483 domain-containing protein
compare
MMJJ
_RS05065
-2.5
-2.9
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS04650
-2.5
-6.3
nitrogenase iron protein
compare
MMJJ
_RS06910
-2.5
-3.3
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS06705
-2.5
-4.5
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS06225
-2.5
-1.9
adenosylmethionine decarboxylase
compare
MMJJ
_RS00360
-2.5
-2.7
adenosylhomocysteinase
compare
MMJJ
_RS03200
-2.5
-2.1
uroporphyrinogen-III synthase
compare
MMJJ
_RS08000
-2.5
-9.1
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS07455
-2.5
-7.3
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS05295
-2.5
-10.8
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS05720
-2.5
-1.8
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS04675
-2.4
-6.8
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS00475
-2.4
-1.9
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS04615
-2.4
-4.0
methanogenesis marker 3 protein
compare
MMJJ
_RS07155
-2.4
-10.0
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS08625
-2.4
-7.8
magnesium/cobalt transporter CorA
compare
MMJJ
_RS06760
-2.4
-4.3
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS05575
-2.4
-3.3
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS07715
-2.4
-2.9
UbiD family decarboxylase
compare
MMJJ
_RS09035
-2.3
-6.0
OB-fold nucleic acid binding domain-containing protein
compare
MMJJ
_RS06860
-2.2
-4.4
hypothetical protein
compare
MMJJ
_RS07190
-2.2
-3.8
RtcB family protein
compare
MMJJ
_RS01785
-2.2
-1.4
50S ribosomal protein L14e
compare
MMJJ
_RS04520
-2.2
-5.0
coenzyme F430 synthase
compare
MMJJ
_RS01830
-2.2
-3.0
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS06840
-2.2
-3.5
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS07415
-2.1
-1.8
polyprenyl diphosphate synthase
compare
MMJJ
_RS08535
-2.1
-3.0
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS03060
-2.1
-2.7
methanogenesis marker 7 protein
compare
MMJJ
_RS06250
-2.1
-1.9
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS05160
-2.1
-2.5
RNA-binding protein
compare
MMJJ
_RS06700
-2.1
-4.1
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS07165
-2.1
-11.4
chromosome segregation protein SMC
compare
MMJJ
_RS06170
-2.1
-7.8
hypothetical protein
compare
MMJJ
_RS06750
-2.1
-1.8
homoaconitase large subunit
compare
MMJJ
_RS04040
-2.1
-6.4
prefoldin subunit beta
compare
MMJJ
_RS07170
-2.1
-4.4
pyridoxal phosphate-dependent aminotransferase
compare
MMJJ
_RS05770
-2.1
-2.1
flagellar protein D
compare
MMJJ
_RS05995
-2.1
-2.1
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06885
-2.1
-2.1
EhaF family protein
compare
MMJJ
_RS01820
-2.0
-3.9
MJ1244 family protein
compare
MMJJ
_RS01600
-2.0
-2.3
radical SAM protein
compare
MMJJ
_RS04680
-2.0
-9.5
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMJJ
_RS04010
-2.0
-5.1
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS06565
-2.0
-4.8
segregation/condensation protein A
compare
MMJJ
_RS07960
-2.0
-2.5
quinolinate synthase NadA
compare
MMJJ
_RS01815
-2.0
-3.7
DUF134 domain-containing protein
compare
MMJJ
_RS08035
-2.0
-5.1
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS01875
-2.0
-6.5
global nitrogen regulator NrpR
compare
MMJJ
_RS04655
-2.0
-3.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS08725
-2.0
-11.3
flippase
compare
MMJJ
_RS06010
-2.0
-6.3
hypothetical protein
compare
MMJJ
_RS06375
-1.9
-3.9
UbiX family flavin prenyltransferase
compare
MMJJ
_RS02935
-1.9
-3.2
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS08020
-1.9
-8.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS07035
-1.9
-2.1
glycosyl transferase
compare
Specific Phenotypes
For 1 genes in this experiment