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Experiment set1IT058 for
Methanococcus maripaludis JJ
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H2 pooled triplicate planktonic cells
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS01865
-5.9
-2.8
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS04200
-5.5
-6.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS02040
-5.1
-1.9
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS01935
-5.1
-2.6
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS04800
-4.9
-5.5
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS00210
-4.8
-1.7
DUF530 family protein
compare
MMJJ
_RS02055
-4.8
-16.3
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS07995
-4.6
-6.7
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS08855
-4.6
-3.2
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS02935
-4.6
-2.5
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS04155
-4.6
-6.3
hypothetical protein
compare
MMJJ
_RS04685
-4.6
-8.2
carbamoyltransferase HypF
compare
MMJJ
_RS08320
-4.4
-2.2
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS09135
-4.4
-9.1
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS02045
-4.4
-2.4
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS04970
-4.4
-1.4
DUF655 domain-containing protein
compare
MMJJ
_RS08850
-4.3
-1.7
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS03670
-4.3
-4.5
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS07360
-4.3
-1.2
TIGR00269 family protein
compare
MMJJ
_RS01870
-4.3
-1.5
methanogenesis marker 15 protein
compare
MMJJ
_RS06215
-4.2
-3.5
agmatinase
compare
MMJJ
_RS02275
-4.2
-3.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06040
-4.2
-2.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS09375
-4.1
-1.5
hypothetical protein
compare
MMJJ
_RS00570
-4.1
-1.5
ribonuclease P
compare
MMJJ
_RS03620
-4.1
-6.2
DUF2097 domain-containing protein
compare
MMJJ
_RS07430
-4.1
-2.7
ribonuclease VapC
compare
MMJJ
_RS03055
-4.0
-2.4
hypothetical protein
compare
MMJJ
_RS07725
-4.0
-2.6
DNA primase DnaG
compare
MMJJ
_RS06725
-4.0
-14.2
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS02200
-4.0
-11.8
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS05650
-4.0
-1.8
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS08340
-3.9
-5.0
archaeoflavoprotein AfpA
compare
MMJJ
_RS01880
-3.9
-2.7
RlmE family RNA methyltransferase
compare
MMJJ
_RS03760
-3.9
-3.0
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS06860
-3.9
-3.1
hypothetical protein
compare
MMJJ
_RS09190
-3.9
-1.0
tryptophan synthase subunit beta
compare
MMJJ
_RS04145
-3.9
-11.2
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS07720
-3.8
-1.6
UPF0058 family protein
compare
MMJJ
_RS03580
-3.8
-1.7
TIGR00303 family protein
compare
MMJJ
_RS08535
-3.8
-1.7
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS07785
-3.8
-1.6
fumarate reductase subunit A
compare
MMJJ
_RS08625
-3.8
-8.3
magnesium/cobalt transporter CorA
compare
MMJJ
_RS04650
-3.8
-5.1
nitrogenase iron protein
compare
MMJJ
_RS03840
-3.7
-3.1
DHH family phosphoesterase
compare
MMJJ
_RS08840
-3.7
-2.1
calcium/sodium antiporter
compare
MMJJ
_RS06695
-3.7
-1.6
amidohydrolase
compare
MMJJ
_RS03095
-3.6
-1.4
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS01350
-3.6
-6.3
sodium:proton antiporter
compare
MMJJ
_RS03150
-3.6
-3.4
2-phospho-L-lactate transferase
compare
MMJJ
_RS05620
-3.6
-4.1
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS03110
-3.5
-3.0
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS07950
-3.5
-2.4
4Fe-4S binding protein
compare
MMJJ
_RS07265
-3.5
-13.7
tRNA (adenine-N1)-methyltransferase
compare
MMJJ
_RS00275
-3.5
-1.2
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03125
-3.5
-3.6
GMC oxidoreductase
compare
MMJJ
_RS07705
-3.5
-1.7
GTP-binding protein EngB
compare
MMJJ
_RS04980
-3.5
-4.9
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS05810
-3.5
-6.5
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS08095
-3.5
-3.7
cobyric acid synthase CobQ
compare
MMJJ
_RS06485
-3.5
-1.6
phosphoglycerate kinase
compare
MMJJ
_RS08155
-3.5
-4.3
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS04790
-3.5
-2.8
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS03785
-3.5
-2.0
hypothetical protein
compare
MMJJ
_RS00125
-3.5
-1.5
KEOPS complex subunit Cgi121
compare
MMJJ
_RS05995
-3.4
-1.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07470
-3.4
-1.1
50S ribosome-binding GTPase
compare
MMJJ
_RS04700
-3.4
-5.9
deoxyhypusine synthase
compare
MMJJ
_RS06390
-3.4
-1.1
NADPH-dependent F420 reductase
compare
MMJJ
_RS01860
-3.4
-14.4
tRNA guanosine(15) transglycosylase TgtA
compare
MMJJ
_RS05065
-3.4
-2.8
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS03190
-3.4
-1.5
phosphopyruvate hydratase
compare
MMJJ
_RS04995
-3.4
-5.0
Tfx family DNA-binding protein
compare
MMJJ
_RS04565
-3.4
-3.4
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS01815
-3.4
-3.4
DUF134 domain-containing protein
compare
MMJJ
_RS05445
-3.4
-1.1
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS05415
-3.4
-1.2
hypothetical protein
compare
MMJJ
_RS05770
-3.3
-1.6
flagellar protein D
compare
MMJJ
_RS06110
-3.3
-2.2
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS00560
-3.3
-2.6
homoisocitrate dehydrogenase
compare
MMJJ
_RS06225
-3.3
-1.2
adenosylmethionine decarboxylase
compare
MMJJ
_RS04050
-3.3
-1.5
dihydroneopterin aldolase family protein
compare
MMJJ
_RS04110
-3.3
-5.9
hypothetical protein
compare
MMJJ
_RS08620
-3.3
-5.1
DUF373 family protein
compare
MMJJ
_RS08080
-3.3
-8.8
TIGR00300 family protein
compare
MMJJ
_RS07715
-3.3
-2.3
UbiD family decarboxylase
compare
MMJJ
_RS02920
-3.3
-1.7
30S ribosomal protein S27ae
compare
MMJJ
_RS03815
-3.3
-1.8
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03310
-3.2
-2.7
hypothetical protein
compare
MMJJ
_RS00270
-3.2
-2.3
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS01810
-3.2
-1.4
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS00550
-3.2
-8.4
AIR synthase-related protein
compare
MMJJ
_RS00475
-3.2
-1.4
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS07000
-3.2
-1.0
TrkH family potassium uptake protein
compare
MMJJ
_RS00215
-3.2
-1.2
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS03865
-3.2
-1.2
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS06910
-3.2
-2.4
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS01755
-3.2
-1.3
ferrous iron transport protein B
compare
MMJJ
_RS05490
-3.2
-1.4
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS05655
-3.2
-6.6
HisA/HisF family protein
compare
MMJJ
_RS08660
-3.2
-2.5
acetylornithine transaminase
compare
MMJJ
_RS00425
-3.2
-3.5
hypothetical protein
compare
MMJJ
_RS01600
-3.1
-1.3
radical SAM protein
compare
MMJJ
_RS05155
-3.1
-4.4
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS05295
-3.1
-14.8
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS06155
-3.1
-5.3
phosphatidylglycerophosphatase A
compare
MMJJ
_RS01750
-3.1
-1.2
ferrous iron transport protein A
compare
MMJJ
_RS07245
-3.1
-4.7
amidohydrolase family protein
compare
MMJJ
_RS01200
-3.1
-1.5
PRC-barrel domain-containing protein
compare
MMJJ
_RS03200
-3.1
-1.1
uroporphyrinogen-III synthase
compare
MMJJ
_RS06855
-3.1
-1.2
DUF2104 domain-containing protein
compare
MMJJ
_RS03155
-3.1
-10.2
hypothetical protein
compare
MMJJ
_RS06510
-3.1
-1.2
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS01820
-3.1
-4.4
MJ1244 family protein
compare
MMJJ
_RS00205
-3.1
-5.0
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS05950
-3.1
-2.8
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS05330
-3.1
-1.8
DNA polymerase II large subunit
compare
MMJJ
_RS06150
-3.0
-4.3
DUF483 domain-containing protein
compare
MMJJ
_RS03820
-3.0
-1.7
hydrogenase formation protein HypD
compare
MMJJ
_RS04675
-3.0
-7.0
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS01355
-3.0
-2.1
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS03615
-3.0
-2.8
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS06700
-3.0
-4.9
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS08795
-3.0
-1.2
phosphoglucosamine mutase
compare
MMJJ
_RS06625
-3.0
-1.3
pyruvate synthase subunit PorB
compare
MMJJ
_RS05260
-3.0
-5.6
ATP-grasp domain-containing protein
compare
MMJJ
_RS06600
-3.0
-1.8
DUF555 domain-containing protein
compare
MMJJ
_RS04150
-2.9
-3.0
DUF5379 domain-containing protein
compare
MMJJ
_RS05590
-2.9
-0.9
homoserine dehydrogenase
compare
MMJJ
_RS06930
-2.9
-1.6
type II methionyl aminopeptidase
compare
MMJJ
_RS08170
-2.9
-1.4
diaminopimelate decarboxylase
compare
MMJJ
_RS05930
-2.9
-1.4
cell division protein SepF
compare
MMJJ
_RS05160
-2.9
-2.6
RNA-binding protein
compare
MMJJ
_RS02090
-2.9
-3.9
tyramine--L-glutamate ligase
compare
MMJJ
_RS06250
-2.9
-1.2
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS08000
-2.9
-8.3
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS06220
-2.9
-4.2
polyamine aminopropyltransferase
compare
MMJJ
_RS05610
-2.9
-3.3
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS03895
-2.8
-2.2
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS01415
-2.8
-1.5
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS05575
-2.8
-3.2
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS08925
-2.8
-11.7
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS07350
-2.8
-3.8
4Fe-4S binding protein
compare
MMJJ
_RS03225
-2.8
-1.5
4Fe-4S binding protein
compare
MMJJ
_RS08010
-2.7
-6.2
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS07945
-2.7
-1.6
4Fe-4S binding protein
compare
MMJJ
_RS06750
-2.7
-1.0
homoaconitase large subunit
compare
MMJJ
_RS03170
-2.7
-7.2
DUF5612 domain-containing protein
compare
MMJJ
_RS07165
-2.7
-14.5
chromosome segregation protein SMC
compare
MMJJ
_RS00580
-2.7
-0.7
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS02190
-2.7
-11.5
molybdopterin biosynthesis protein
compare
MMJJ
_RS08250
-2.7
-5.7
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS08055
-2.7
-6.5
methanogenesis marker 14 protein
compare
MMJJ
_RS06805
-2.7
-2.4
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS09085
-2.7
-13.7
minichromosome maintenance protein MCM
compare
MMJJ
_RS09055
-2.7
-8.8
NFACT family protein
compare
MMJJ
_RS08335
-2.7
-1.8
ABC transporter ATP-binding protein
compare
MMJJ
_RS04520
-2.7
-4.6
coenzyme F430 synthase
compare
MMJJ
_RS04670
-2.7
-4.4
DUF2117 domain-containing protein
compare
MMJJ
_RS07980
-2.6
-10.3
biotin synthase BioB
compare
MMJJ
_RS06240
-2.6
-1.4
dihydropteroate synthase-like protein
compare
MMJJ
_RS06255
-2.6
-5.4
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS03875
-2.6
-2.7
CBS domain-containing protein
compare
MMJJ
_RS07375
-2.6
-8.4
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMJJ
_RS04730
-2.6
-2.2
tyrosine decarboxylase MfnA
compare
MMJJ
_RS06840
-2.6
-2.4
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS00520
-2.6
-7.1
PDGLE domain-containing protein
compare
MMJJ
_RS06170
-2.6
-9.8
hypothetical protein
compare
MMJJ
_RS01830
-2.5
-3.0
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS05720
-2.5
-1.1
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS07410
-2.5
-2.8
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS08575
-2.5
-2.9
hypothetical protein
compare
MMJJ
_RS05725
-2.5
-12.4
UPF0179 family protein
compare
MMJJ
_RS01345
-2.5
-3.9
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS03060
-2.5
-2.7
methanogenesis marker 7 protein
compare
MMJJ
_RS07190
-2.5
-2.4
RtcB family protein
compare
MMJJ
_RS04505
-2.5
-6.2
CDC48 family AAA ATPase
compare
MMJJ
_RS03540
-2.5
-4.6
TIGR00289 family protein
compare
MMJJ
_RS03005
-2.5
-2.1
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS00450
-2.5
-1.2
DUF126 domain-containing protein
compare
MMJJ
_RS01405
-2.5
-0.8
proline--tRNA ligase
compare
MMJJ
_RS08020
-2.5
-9.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS07455
-2.5
-7.0
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07370
-2.5
-4.6
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS09300
-2.5
-2.2
hypothetical protein
compare
MMJJ
_RS07415
-2.4
-1.3
polyprenyl diphosphate synthase
compare
MMJJ
_RS06730
-2.4
-6.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03230
-2.4
-2.9
NAD(P)/FAD-dependent oxidoreductase
compare
MMJJ
_RS06050
-2.4
-7.4
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS00530
-2.4
-14.2
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS05070
-2.4
-1.4
DNA primase catalytic subunit PriS
compare
MMJJ
_RS06760
-2.4
-3.3
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS06180
-2.4
-1.9
tryptophan--tRNA ligase
compare
MMJJ
_RS08035
-2.3
-6.2
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS01825
-2.3
-5.9
DNA repair and recombination protein RadB
compare
MMJJ
_RS01690
-2.3
-2.5
methanogenesis marker 12 protein
compare
MMJJ
_RS00370
-2.3
-1.0
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS01475
-2.3
-1.1
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS00600
-2.3
-1.8
hydroxymethylbilane synthase
compare
MMJJ
_RS03240
-2.3
-2.1
histone family protein
compare
Specific Phenotypes
For 2 genes in this experiment