Experiment set1IT046 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with 1-ethyl-3-methylimidazolium chloride 10 mM

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_3490 +1.5 10.1 Response regulator receiver domain/Sigma-70, region 4 compare
Ga0059261_3492 +1.4 8.8 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_0208 +1.3 5.8 Response regulator receiver domain compare
Ga0059261_3579 +1.0 4.1 hypothetical protein compare
Ga0059261_3581 +1.0 6.0 Alpha/beta hydrolase family compare
Ga0059261_1795 +0.9 5.4 Predicted nucleoside-diphosphate-sugar epimerases compare
Ga0059261_3947 +0.8 2.2 type II secretion system protein I (GspI) compare
Ga0059261_0035 +0.7 1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_1122 +0.7 2.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Ga0059261_3507 +0.7 6.3 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_0252 +0.7 2.5 SpoIIAA-like compare
Ga0059261_0757 +0.7 2.1 Predicted transcriptional regulators compare
Ga0059261_3545 +0.7 1.3 hypothetical protein compare
Ga0059261_0957 +0.7 1.5 Protein of unknown function (DUF2798) compare
Ga0059261_2126 +0.6 4.1 ETC complex I subunit conserved region compare
Ga0059261_4217 +0.6 1.6 hypothetical protein compare
Ga0059261_4139 +0.6 1.8 hypothetical protein compare
Ga0059261_1145 +0.6 1.6 flagella basal body P-ring formation protein FlgA compare
Ga0059261_1380 +0.6 4.5 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1772 +0.6 1.8 MobA/MobL family compare
Ga0059261_0973 +0.6 2.0 hypothetical protein compare
Ga0059261_4192 +0.6 2.3 ATPases involved in chromosome partitioning compare
Ga0059261_3371 +0.5 1.5 hypothetical protein compare
Ga0059261_2471 +0.5 1.2 hypothetical protein compare
Ga0059261_1126 +0.5 1.8 Response regulator compare
Ga0059261_0980 +0.5 3.5 polyhydroxyalkanoate synthesis repressor PhaR compare
Ga0059261_3755 +0.5 1.3 Protein of unknown function (DUF2798) compare
Ga0059261_1830 +0.5 1.0 hypothetical protein compare
Ga0059261_3720 +0.5 2.1 Integral membrane protein CcmA involved in cell shape determination compare
Ga0059261_1774 +0.5 1.0 hypothetical protein compare
Ga0059261_0244 +0.5 1.5 FOG: CheY-like receiver compare
Ga0059261_1811 +0.4 1.5 ATP:cob(I)alamin adenosyltransferase compare
Ga0059261_2188 +0.4 1.6 Uncharacterized conserved protein compare
Ga0059261_3491 +0.4 2.8 hypothetical protein compare
Ga0059261_0246 +0.4 1.2 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
Ga0059261_1759 +0.4 1.3 Phosphoadenosine phosphosulfate reductase family compare
Ga0059261_4134 +0.4 1.8 tRNA compare
Ga0059261_2376 +0.4 2.2 phage tail protein, P2 protein I family compare
Ga0059261_3356 +0.4 0.8 hypothetical protein compare
Ga0059261_0083 +0.4 0.8 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (EC 6.3.5.-) compare
Ga0059261_2685 +0.4 2.2 Putative translation initiation inhibitor, yjgF family compare
Ga0059261_1064 +0.4 1.2 Uncharacterized conserved protein compare
Ga0059261_0817 +0.4 2.2 GTP-binding protein TypA/BipA compare
Ga0059261_2691 +0.4 1.6 Zn-dependent dipeptidase, microsomal dipeptidase homolog compare
Ga0059261_3165 +0.4 2.4 PEP phosphonomutase and related enzymes compare
Ga0059261_3287 +0.4 2.9 Topoisomerase IB compare
Ga0059261_0887 +0.4 1.5 Predicted transcriptional regulators compare
Ga0059261_2731 +0.4 1.7 transcriptional regulator, AraC family compare
Ga0059261_1934 +0.4 1.4 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Ga0059261_2314 +0.4 1.3 Protein-disulfide isomerase compare
Ga0059261_0102 +0.4 2.7 endopeptidase La compare
Ga0059261_3573 +0.4 2.5 Bacterial PH domain compare
Ga0059261_1588 +0.4 2.5 Methyltransferase domain compare
Ga0059261_3706 +0.4 1.7 RF-1 domain compare
Ga0059261_3700 +0.3 1.1 Transcriptional regulator compare
Ga0059261_1573 +0.3 1.9 hypothetical protein compare
Ga0059261_2933 +0.3 2.1 hypothetical protein compare
Ga0059261_1571 +0.3 3.0 SapC compare
Ga0059261_3083 +0.3 1.6 hypothetical protein compare
Ga0059261_1300 +0.3 1.0 hypothetical protein compare
Ga0059261_0412 +0.3 1.2 DNA-binding HTH domain-containing proteins compare
Ga0059261_1519 +0.3 1.3 NUDIX domain compare
Ga0059261_1737 +0.3 2.0 hypothetical protein compare
Ga0059261_0719 +0.3 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_2658 +0.3 1.3 Transcriptional regulators compare
Ga0059261_1381 +0.3 1.7 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1577 +0.3 2.8 L-glutamine and L-histidine transporter (from data) compare
Ga0059261_1762 +0.3 0.7 hypothetical protein compare
Ga0059261_2371 +0.3 1.4 hypothetical protein compare
Ga0059261_1599 +0.3 2.9 Uncharacterized conserved protein compare
Ga0059261_0773 +0.3 1.3 Esterase/lipase compare
Ga0059261_2222 +0.3 2.0 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Ga0059261_3635 +0.3 1.3 Predicted integral membrane protein compare
Ga0059261_1263 +0.3 1.3 hypothetical protein compare
Ga0059261_0662 +0.3 1.4 Truncated hemoglobins compare
Ga0059261_3233 +0.3 1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0448 +0.3 0.7 hypothetical protein compare
Ga0059261_3959 +0.3 1.0 MerC mercury resistance protein compare
Ga0059261_3207 +0.3 1.5 Disulfide bond chaperones of the HSP33 family compare
Ga0059261_2413 +0.3 0.8 hypothetical protein compare
Ga0059261_3566 +0.3 1.5 hypothetical protein compare
Ga0059261_0357 +0.3 0.9 hypothetical protein compare
Ga0059261_3132 +0.3 1.7 hypothetical protein compare
Ga0059261_1739 +0.3 1.4 Conjugal transfer protein TraD compare
Ga0059261_2914 +0.3 0.9 Type IV secretory pathway, TrbD component compare
Ga0059261_1606 +0.3 1.8 Domain of unknown function (DUF4281) compare
Ga0059261_1860 +0.3 0.7 Transposase compare
Ga0059261_2215 +0.3 1.0 Thiamine monophosphate synthase compare
Ga0059261_0935 +0.3 1.3 Uncharacterized conserved protein compare
Ga0059261_3050 +0.3 2.2 N-acyl-L-homoserine lactone synthetase compare
Ga0059261_1763 +0.3 1.2 hypothetical protein compare
Ga0059261_1130 +0.3 2.0 hypothetical protein compare
Ga0059261_0225 +0.3 2.6 polyphosphate kinase 1 compare
Ga0059261_4184 +0.3 1.8 exosortase A system-associated hydrolase 1 compare
Ga0059261_1292 +0.3 1.0 hypothetical protein compare
Ga0059261_3411 +0.3 1.8 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_0993 +0.3 0.6 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_1396 +0.3 1.4 EF-hand domain pair compare
Ga0059261_0770 +0.3 0.7 hypothetical protein compare
Ga0059261_1962 +0.3 1.1 RNase HII (EC 3.1.26.4) compare
Ga0059261_3808 +0.3 0.9 Pyrroline-5-carboxylate reductase compare
Ga0059261_1768 +0.3 0.4 Sigma-70 region 2 compare
Ga0059261_2145 +0.3 1.3 ribosome-binding factor A compare
Ga0059261_1304 +0.3 1.9 membrane protein, MarC family compare
Ga0059261_2736 +0.3 1.6 hypothetical protein compare
Ga0059261_1197 +0.3 1.1 hypothetical protein compare
Ga0059261_0750 +0.3 1.4 NADH:ubiquinone oxidoreductase subunit 3 (chain A) compare
Ga0059261_1117 +0.3 1.5 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain compare
Ga0059261_1071 +0.3 0.8 hypothetical protein compare
Ga0059261_2097 +0.3 1.3 Rod binding protein compare
Ga0059261_3257 +0.3 1.5 glycine cleavage system H protein compare
Ga0059261_1260 +0.3 2.0 cobaltochelatase CobT subunit (EC 6.6.1.2) compare
Ga0059261_3058 +0.3 1.7 hypothetical protein compare
Ga0059261_1743 +0.3 0.9 hypothetical protein compare
Ga0059261_1410 +0.3 1.4 Fructose-2,6-bisphosphatase compare
Ga0059261_0388 +0.3 1.7 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_0199 +0.3 1.4 hypothetical protein compare
Ga0059261_3208 +0.3 0.6 hypothetical protein compare
Ga0059261_3833 +0.3 1.0 hypothetical protein compare
Ga0059261_2063 +0.3 1.1 Flagellar biosynthesis protein, FliO compare
Ga0059261_0472 +0.3 1.0 Predicted metal-binding protein compare
Ga0059261_1611 +0.3 2.3 Glucose/sorbosone dehydrogenases compare
Ga0059261_0099 +0.3 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_3216 +0.3 1.2 Acetyltransferases compare
Ga0059261_3368 +0.3 1.4 Predicted transcriptional regulator compare
Ga0059261_3815 +0.3 1.2 hypothetical protein compare
Ga0059261_3193 +0.3 2.3 Dolichyl-phosphate-mannose-protein mannosyltransferase compare
Ga0059261_0621 +0.3 1.2 cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) compare
Ga0059261_1825 +0.3 1.4 hypothetical protein compare
Ga0059261_0459 +0.3 1.0 Heavy-metal resistance compare
Ga0059261_0219 +0.3 2.1 Lactate dehydrogenase and related dehydrogenases compare
Ga0059261_3727 +0.3 1.2 hypothetical protein compare
Ga0059261_1303 +0.3 1.3 hypothetical protein compare
Ga0059261_3125 +0.3 0.7 Imidazoleglycerol-phosphate synthase compare
Ga0059261_0821 +0.3 1.4 hypothetical protein compare
Ga0059261_2766 +0.3 1.5 2'-5' RNA ligase compare
Ga0059261_0263 +0.3 1.5 3-oxoacid CoA-transferase, B subunit compare
Ga0059261_3714 +0.3 1.0 Acyl-CoA hydrolase compare
Ga0059261_2749 +0.3 2.0 transcriptional regulator, TetR family compare
Ga0059261_0867 +0.3 1.6 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_3134 +0.3 1.7 hypothetical protein compare
Ga0059261_2422 +0.3 1.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_4229 +0.3 1.7 Predicted transcriptional regulator compare
Ga0059261_1595 +0.3 2.3 Membrane protein involved in the export of O-antigen and teichoic acid compare
Ga0059261_0143 +0.3 1.7 hypothetical protein compare
Ga0059261_3142 +0.3 2.0 Predicted permeases compare
Ga0059261_0098 +0.2 1.5 Carbohydrate binding domain compare
Ga0059261_4120 +0.2 0.5 Stress responsive A/B Barrel Domain compare
Ga0059261_2132 +0.2 0.9 transcriptional regulator, BadM/Rrf2 family compare
Ga0059261_2617 +0.2 1.2 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_1905 +0.2 1.8 Serine acetyltransferase compare
Ga0059261_3270 +0.2 1.5 hypothetical protein compare
Ga0059261_4204 +0.2 1.1 transcriptional regulator, TetR family compare
Ga0059261_3441 +0.2 0.9 hypothetical protein compare
Ga0059261_1335 +0.2 1.0 Predicted ATPase compare
Ga0059261_0402 +0.2 1.5 Uncharacterized conserved protein compare
Ga0059261_1147 +0.2 1.7 Bacterial flagellin N-terminal helical region/Bacterial flagellin C-terminal helical region compare
Ga0059261_3292 +0.2 1.6 hypothetical protein compare
Ga0059261_1730 +0.2 0.8 Surface presentation of antigens (SPOA) compare
Ga0059261_3638 +0.2 0.8 Predicted integral membrane protein (DUF2282) compare
Ga0059261_1103 +0.2 1.7 flagellar biosynthetic protein FlhB compare
Ga0059261_0871 +0.2 1.6 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Ga0059261_0906 +0.2 1.1 Uncharacterized conserved protein compare
Ga0059261_2239 +0.2 1.5 tRNA and rRNA cytosine-C5-methylases compare
Ga0059261_0220 +0.2 1.7 L-serine dehydratase, iron-sulfur-dependent, single chain form compare
Ga0059261_1138 +0.2 0.8 hypothetical protein compare
Ga0059261_0600 +0.2 1.5 CDP-glucose 4,6-dehydratase compare
Ga0059261_3762 +0.2 1.2 Uncharacterized conserved protein compare
Ga0059261_0039 +0.2 1.0 His Kinase A (phospho-acceptor) domain compare
Ga0059261_1557 +0.2 0.9 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase compare
Ga0059261_2315 +0.2 1.7 Protein-disulfide isomerase compare
Ga0059261_1156 +0.2 2.0 Dolichyl-phosphate-mannose-protein mannosyltransferase compare
Ga0059261_0298 +0.2 1.3 TonB family C-terminal domain compare
Ga0059261_0905 +0.2 1.4 Protein of unknown function (DUF998) compare
Ga0059261_2434 +0.2 1.5 Putative translation initiation inhibitor, yjgF family compare
Ga0059261_3646 +0.2 1.0 Uncharacterized stress protein (general stress protein 26) compare
Ga0059261_3915 +0.2 1.1 hypothetical protein compare
Ga0059261_1040 +0.2 1.6 fumarase, class II (EC 4.2.1.2) compare
Ga0059261_1546 +0.2 1.6 MerC mercury resistance protein compare
Ga0059261_3094 +0.2 1.3 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase/FKBP-type peptidyl-prolyl cis-trans isomerase compare
Ga0059261_0073 +0.2 1.2 hypothetical protein compare
Ga0059261_0140 +0.2 1.5 tRNA-U20-dihydrouridine synthase compare
Ga0059261_1570 +0.2 1.5 N-formylglutamate amidohydrolase compare
Ga0059261_2056 +0.2 1.6 Predicted acyl-CoA transferases/carnitine dehydratase compare
Ga0059261_1394 +0.2 1.5 putative efflux protein, MATE family compare
Ga0059261_1597 +0.2 1.2 hypothetical protein compare
Ga0059261_3498 +0.2 0.9 Iron-sulfur cluster assembly accessory protein compare
Ga0059261_1131 +0.2 1.3 flagellar protein export ATPase FliI compare
Ga0059261_1149 +0.2 1.7 hypothetical protein compare
Ga0059261_1496 +0.2 1.1 uroporphyrin-III C-methyltransferase compare
Ga0059261_2331 +0.2 1.2 hypothetical protein compare
Ga0059261_3719 +0.2 1.9 Imidazolonepropionase and related amidohydrolases compare
Ga0059261_0121 +0.2 0.5 Sporulation related domain compare
Ga0059261_0237 +0.2 0.8 phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Ga0059261_2846 +0.2 1.2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_1536 +0.2 1.5 Glutathione S-transferase compare
Ga0059261_1003 +0.2 1.4 hypothetical protein compare
Ga0059261_1756 +0.2 0.4 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes compare
Ga0059261_1449 +0.2 1.4 Glycine zipper 2TM domain compare
Ga0059261_0832 +0.2 1.8 Predicted permease compare


Specific Phenotypes

For 1 genes in this experiment

For stress 1-ethyl-3-methylimidazolium chloride in Sphingomonas koreensis DSMZ 15582

For stress 1-ethyl-3-methylimidazolium chloride across organisms