Experiment set1IT045 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with copper (II) chloride dihydrate 2.5 mM

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_68 -3.7 -2.6 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf1N1B4_3246 -3.1 -5.0 RND efflux system, inner membrane transporter CmeB compare
Pf1N1B4_2006 -2.7 -3.6 hypothetical protein compare
Pf1N1B4_2291 -2.6 -9.5 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) conserved
Pf1N1B4_1262 -2.5 -7.0 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf1N1B4_4038 -2.1 -2.7 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
Pf1N1B4_2106 -2.0 -3.8 Hydrogen peroxide-inducible genes activator compare
Pf1N1B4_327 -2.0 -2.6 hypothetical protein compare
Pf1N1B4_1554 -1.9 -6.9 predicted FeS cluster maintenance protein (from data) compare
Pf1N1B4_1624 -1.9 -7.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf1N1B4_5275 -1.8 -2.1 hypothetical protein compare
Pf1N1B4_1626 -1.8 -6.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf1N1B4_5278 -1.8 -2.1 hypothetical protein compare
Pf1N1B4_769 -1.8 -5.5 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_2247 -1.7 -2.8 FMN reductase (EC 1.5.1.29) compare
Pf1N1B4_3906 -1.7 -3.1 DNA topoisomerase I (EC 5.99.1.2) compare
Pf1N1B4_1993 -1.7 -1.9 C4-type zinc finger protein, DksA/TraR family compare
Pf1N1B4_1844 -1.7 -9.6 Oligopeptidase A (EC 3.4.24.70) compare
Pf1N1B4_1263 -1.6 -2.8 Cu(I)-responsive transcriptional regulator compare
Pf1N1B4_5059 -1.6 -2.7 Transcriptional regulator, LysR family compare
Pf1N1B4_4028 -1.6 -3.6 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
Pf1N1B4_1565 -1.6 -3.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf1N1B4_5668 -1.6 -3.0 Peptidase, U7 family compare
Pf1N1B4_1105 -1.6 -2.0 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
Pf1N1B4_5892 -1.6 -2.9 FIG00961753: hypothetical protein compare
Pf1N1B4_1617 -1.5 -6.0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_1 -1.5 -3.4 Colicin V production protein compare
Pf1N1B4_208 -1.5 -3.3 Two-component system response regulator QseB compare
Pf1N1B4_4728 -1.5 -3.4 Na+/H+ antiporter NhaB compare
Pf1N1B4_66 -1.5 -4.1 Copper tolerance protein compare
Pf1N1B4_2290 -1.5 -2.9 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf1N1B4_2568 -1.5 -3.0 Translation elongation factor Tu compare
Pf1N1B4_2356 -1.4 -3.2 hypothetical protein compare
Pf1N1B4_4982 -1.4 -2.2 Transcriptional regulator, AraC family compare
Pf1N1B4_4040 -1.4 -2.7 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
Pf1N1B4_4611 -1.4 -2.6 GlpG protein (membrane protein of glp regulon) compare
Pf1N1B4_1812 -1.4 -2.7 Iron siderophore sensor protein compare
Pf1N1B4_5425 -1.4 -2.2 DNA-binding protein HU-beta compare
Pf1N1B4_3917 -1.3 -3.4 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf1N1B4_3998 -1.3 -3.7 putative exported protein compare
Pf1N1B4_412 -1.3 -2.5 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf1N1B4_197 -1.3 -2.0 FIG139991: Putative thiamine pyrophosphate-requiring enzyme compare
Pf1N1B4_1627 -1.3 -3.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf1N1B4_2489 -1.3 -3.8 Biotin synthesis protein BioH compare
Pf1N1B4_3538 -1.3 -1.6 Transcriptional regulator, AraC family compare
Pf1N1B4_683 -1.3 -3.0 Fumarate hydratase class I, aerobic (EC 4.2.1.2) compare
Pf1N1B4_2169 -1.2 -2.2 FIG00953808: hypothetical protein compare
Pf1N1B4_5014 -1.2 -2.3 Glutathione reductase (EC 1.8.1.7) compare
Pf1N1B4_644 -1.2 -1.7 Cold shock protein CspC compare
Pf1N1B4_211 -1.2 -8.3 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase compare
Pf1N1B4_4139 -1.2 -2.0 Transcriptional regulator, MerR family compare
Pf1N1B4_3647 -1.2 -7.0 Cytochrome c heme lyase subunit CcmH compare
Pf1N1B4_1781 -1.2 -1.4 hypothetical protein compare
Pf1N1B4_5864 -1.2 -1.9 Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF compare
Pf1N1B4_3413 -1.2 -1.6 Transcriptional regulator, LysR family compare
Pf1N1B4_44 -1.2 -6.8 Multicopper oxidase conserved
Pf1N1B4_69 -1.2 -2.3 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_3768 -1.2 -2.2 Homoserine/homoserine lactone efflux protein compare
Pf1N1B4_4437 -1.2 -2.3 hypothetical protein compare
Pf1N1B4_3879 -1.1 -7.9 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) compare
Pf1N1B4_1408 -1.1 -3.2 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf1N1B4_1830 -1.1 -5.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf1N1B4_4851 -1.1 -2.2 Transcriptional regulator of various polyols utilization, AraC family compare
Pf1N1B4_1695 -1.1 -1.4 Cystine ABC transporter, ATP-binding protein compare
Pf1N1B4_2224 -1.1 -1.9 FIG00953390: hypothetical protein compare
Pf1N1B4_5859 -1.1 -2.5 Glutamate carboxypeptidase (EC 3.4.17.11) compare
Pf1N1B4_1612 -1.1 -1.6 FIG00955429: hypothetical protein compare
Pf1N1B4_1057 -1.1 -2.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_3396 -1.1 -2.1 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf1N1B4_1180 -1.1 -1.4 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_4810 -1.1 -2.5 Polymyxin resistance protein PmrM compare
Pf1N1B4_2488 -1.0 -4.4 8-amino-7-oxononanoate synthase (EC 2.3.1.47) compare
Pf1N1B4_3445 -1.0 -2.6 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf1N1B4_2368 -1.0 -3.0 Malonate transporter, MadL subunit compare
Pf1N1B4_5311 -1.0 -1.6 hypothetical protein compare
Pf1N1B4_1806 -1.0 -1.9 FIG00953743: hypothetical protein compare
Pf1N1B4_2706 -1.0 -2.1 FIG00954871: hypothetical protein compare
Pf1N1B4_3836 -1.0 -2.0 Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4) compare
Pf1N1B4_501 -1.0 -1.4 Flp pilus assembly protein RcpC/CpaB compare
Pf1N1B4_4962 -1.0 -2.8 C4-dicarboxylate transport protein compare
Pf1N1B4_2377 -1.0 -4.2 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) compare
Pf1N1B4_2487 -1.0 -5.2 Biotin synthase (EC 2.8.1.6) compare
Pf1N1B4_1614 -1.0 -2.0 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf1N1B4_1403 -1.0 -4.5 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_5542 -1.0 -1.8 hypothetical protein compare
Pf1N1B4_1831 -1.0 -6.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf1N1B4_5812 -1.0 -2.7 FIG00955248: hypothetical protein compare
Pf1N1B4_5663 -1.0 -1.9 Periplasmic sugar-binding domain protein compare
Pf1N1B4_3451 -1.0 -2.4 Aspartokinase (EC 2.7.2.4) compare
Pf1N1B4_1462 -1.0 -6.4 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
Pf1N1B4_2352 -1.0 -3.9 Glutathione synthetase (EC 6.3.2.3) compare
Pf1N1B4_4250 -1.0 -1.8 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_970 -1.0 -6.1 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf1N1B4_4646 -1.0 -2.8 Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) compare
Pf1N1B4_6035 -0.9 -1.7 D-ribose ABC transporter, substrate-binding component RbsB (from data) compare
Pf1N1B4_2490 -0.9 -3.8 Biotin synthesis protein BioC compare
Pf1N1B4_2886 -0.9 -6.4 Paraquat-inducible protein B compare
Pf1N1B4_969 -0.9 -8.6 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf1N1B4_3880 -0.9 -6.1 hypothetical protein compare
Pf1N1B4_448 -0.9 -1.5 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf1N1B4_1566 -0.9 -4.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf1N1B4_4961 -0.9 -2.4 FIG00441227: hypothetical protein compare
Pf1N1B4_3168 -0.9 -2.1 AmpG permease compare
Pf1N1B4_1060 -0.9 -1.7 FIG137478: Hypothetical protein YbgI compare
Pf1N1B4_3241 -0.9 -1.7 hypothetical protein compare
Pf1N1B4_2270 -0.9 -2.3 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Pf1N1B4_4992 -0.9 -2.5 Dienelactone hydrolase and related enzymes compare
Pf1N1B4_1399 -0.9 -2.5 FIG003573: hypothetical protein compare
Pf1N1B4_1334 -0.9 -1.5 FIG00955840: hypothetical protein compare
Pf1N1B4_3234 -0.9 -2.2 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf1N1B4_4343 -0.9 -2.2 hypothetical protein compare
Pf1N1B4_2322 -0.9 -1.8 FIG015547: peptidase, M16 family compare
Pf1N1B4_1067 -0.9 -2.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf1N1B4_1845 -0.9 -2.1 FIG00954395: hypothetical protein compare
Pf1N1B4_5870 -0.9 -2.0 VgrG protein compare
Pf1N1B4_1034 -0.9 -2.5 hypothetical protein compare
Pf1N1B4_4594 -0.9 -1.8 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) compare
Pf1N1B4_309 -0.9 -2.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_32 -0.9 -2.3 Transcriptional regulator, TetR family compare
Pf1N1B4_5814 -0.9 -2.3 putative membrane protein compare
Pf1N1B4_3800 -0.9 -1.6 Enoyl-CoA hydratase/isomerase family protein compare
Pf1N1B4_5498 -0.9 -0.9 hypothetical protein compare
Pf1N1B4_3872 -0.9 -4.7 Putative analog of CcoH, COG3198 compare
Pf1N1B4_3264 -0.9 -1.5 Methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_4670 -0.9 -2.9 Sensory box/GGDEF family protein compare
Pf1N1B4_3518 -0.9 -1.8 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
Pf1N1B4_996 -0.9 -2.1 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf1N1B4_4671 -0.9 -1.9 Short-chain dehydrogenase/reductase SDR compare
Pf1N1B4_1375 -0.9 -4.9 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
Pf1N1B4_373 -0.9 -1.9 5-methylaminomethyl-2-thiouridine-forming enzyme mnmC compare
Pf1N1B4_4563 -0.9 -1.7 Sulfate transporter compare
Pf1N1B4_4429 -0.9 -1.4 No significant database matches compare
Pf1N1B4_630 -0.8 -3.1 TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain compare
Pf1N1B4_324 -0.8 -1.5 Glycosyl transferase, group 2 family protein compare
Pf1N1B4_1573 -0.8 -3.0 Glucans biosynthesis protein G precursor compare
Pf1N1B4_1474 -0.8 -2.9 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) compare
Pf1N1B4_846 -0.8 -1.0 hypothetical protein compare
Pf1N1B4_2491 -0.8 -2.3 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_2433 -0.8 -1.9 FIG00953108: hypothetical protein compare
Pf1N1B4_3812 -0.8 -4.0 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
Pf1N1B4_4957 -0.8 -1.7 Transcriptional regulator, TetR family compare
Pf1N1B4_5493 -0.8 -3.5 hypothetical protein compare
Pf1N1B4_4238 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_438 -0.8 -2.8 hypothetical protein compare
Pf1N1B4_678 -0.8 -4.0 Pyruvate kinase (EC 2.7.1.40) compare
Pf1N1B4_5652 -0.8 -1.9 ChlI component of cobalt chelatase involved in B12 biosynthesis compare
Pf1N1B4_3876 -0.8 -4.2 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf1N1B4_980 -0.8 -1.4 hypothetical protein compare
Pf1N1B4_5329 -0.8 -2.0 hypothetical protein compare
Pf1N1B4_4177 -0.8 -1.3 transcriptional regulator, Crp/Fnr family compare
Pf1N1B4_5151 -0.8 -1.7 FIG002283: Isochorismatase family protein compare
Pf1N1B4_176 -0.8 -2.6 Acetylpolyamine aminohydrolase compare
Pf1N1B4_5261 -0.8 -1.5 hypothetical protein compare
Pf1N1B4_1762 -0.8 -2.3 FIG00957387: hypothetical protein compare
Pf1N1B4_2534 -0.8 -1.2 DnaJ-like protein DjlA compare
Pf1N1B4_2035 -0.8 -3.1 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf1N1B4_5823 -0.8 -1.2 Na(+) H(+) antiporter subunit C compare
Pf1N1B4_3585 -0.8 -2.0 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) compare
Pf1N1B4_5645 -0.8 -1.9 Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2) compare
Pf1N1B4_2912 -0.8 -1.3 GTP-binding and nucleic acid-binding protein YchF compare
Pf1N1B4_485 -0.8 -1.4 L-lysine permease compare
Pf1N1B4_3078 -0.8 -1.5 FIG138056: a glutathione-dependent thiol reductase compare
Pf1N1B4_3595 -0.8 -1.4 Flagellin protein FlaG compare
Pf1N1B4_4336 -0.8 -1.9 FMN-dependent NADH-azoreductase compare
Pf1N1B4_2549 -0.8 -3.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf1N1B4_4818 -0.8 -1.5 RNA polymerase sigma-70 factor, ECF subfamily compare
Pf1N1B4_5051 -0.8 -1.6 Sensor protein DegS compare
Pf1N1B4_5015 -0.8 -2.3 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
Pf1N1B4_4872 -0.8 -1.7 Short-chain dehydrogenase/reductase SDR compare
Pf1N1B4_3527 -0.8 -2.6 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit compare
Pf1N1B4_4381 -0.8 -1.8 Transcriptional regulator, LysR family compare
Pf1N1B4_4143 -0.8 -2.1 hypothetical protein compare
Pf1N1B4_2163 -0.7 -1.2 hypothetical protein compare
Pf1N1B4_4255 -0.7 -2.0 Putative phosphatase YfbT compare
Pf1N1B4_5004 -0.7 -2.6 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf1N1B4_4029 -0.7 -1.9 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
Pf1N1B4_710 -0.7 -1.7 Transporter, LysE family compare
Pf1N1B4_4295 -0.7 -1.3 FIG00954434: hypothetical protein compare
Pf1N1B4_210 -0.7 -4.6 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) compare
Pf1N1B4_2695 -0.7 -1.1 Rare lipoprotein A precursor compare
Pf1N1B4_2949 -0.7 -1.0 FIG00956396: hypothetical protein compare
Pf1N1B4_6031 -0.7 -2.4 Ribokinase (EC 2.7.1.15) (from data) compare
Pf1N1B4_867 -0.7 -2.1 Serine acetyltransferase (EC 2.3.1.30) compare
Pf1N1B4_117 -0.7 -2.5 Iron siderophore sensor protein compare
Pf1N1B4_45 -0.7 -3.1 Copper resistance protein B compare
Pf1N1B4_5107 -0.7 -2.0 Putative collagenase compare
Pf1N1B4_4921 -0.7 -1.7 Haloacid dehalogenase, type II compare
Pf1N1B4_3497 -0.7 -2.2 Heat shock protein compare
Pf1N1B4_4208 -0.7 -1.4 organophosphate pesticide hydrolase compare
Pf1N1B4_3745 -0.7 -1.8 Thiamin ABC transporter, transmembrane component compare
Pf1N1B4_2047 -0.7 -1.9 Chorismate--pyruvate lyase (EC 4.1.3.40) compare
Pf1N1B4_4039 -0.7 -3.0 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
Pf1N1B4_4817 -0.7 -2.2 Fe2+-dicitrate sensor, membrane component compare
Pf1N1B4_3878 -0.7 -3.4 Cytochrome c oxidase subunit CcoO (EC 1.9.3.1) compare
Pf1N1B4_1569 -0.7 -4.9 Twin-arginine translocation protein TatC compare
Pf1N1B4_971 -0.7 -5.2 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf1N1B4_4392 -0.7 -2.1 MocE compare
Pf1N1B4_3143 -0.7 -1.5 RecA protein compare
Pf1N1B4_1301 -0.7 -1.6 secreted protein Hcp compare
Pf1N1B4_3751 -0.7 -1.2 FIG00953060: hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N1B4

For stress copper (II) chloride dihydrate across organisms